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Tetrabenazine (TBZ), which increases degradation of dopamine, effectively suppresses chorea in Huntington Disease when administered long-term, but observed increases in parkinsonism and dysphagia side effects require further monitoring.
Contrary to common belief, evidence from the literature suggests brief passive psychoeducational interventions for depression, anxiety and psychological distress can improve symptoms and are inexpensive and easy to implement, although the effect depends on the quality of psychoeducation administered.
An age-standardised motor function test, NUBU, aids differentiation between ADHD and bipolar disorder (BD) in children, which is often difficult because ongoing neural development causes similar symptoms in both disorders.
Rats made to exercise on a treadmill after spinal transection show improved stepping ability and this is associated with increasing BDNF accumulation in two cell types and changes of innervation indicated by a region-specific increase of presynaptic markers.
According to the literature, the combined use of cannabidiol and delta-9-tetrahydrocannabinol extracts in multiple sclerosis often results in patients reporting symptom relief, although there is no significant improvement to spasticity as a result of this therapy.
