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Prebiotics are believed to favor beneficial gut bacteria, but mice fed 10% fructo-oligosaccharide or xylo-saccharide prior to oral challenge with Salmonella acquired higher levels of this pathogen in their internal organs than mice fed only cornstarch.
An extract of broccoli sprouts enriched with selenium inhibits proliferation, induces apoptosis and decreases prostate-specific antigen secretion in human prostate cancer cell lines, showing potential of this nutriceutical for prostate cancer management.
Essential genes of the bacterium Wolbachia have been predicted using computational methods, identifying potential new targets for drugs to treat lymphatic filiariasis caused by the Wolbachia-harboring nematode Brugia malayi.
Different social contact patterns between school holidays and term time and between weekdays and weekends result in a 20% decrease of secondary infections during holiday periods, suggesting that closing schools could reduce infection spread during a pandemic.
HIV causes immunodeficiency by deleting activated CD4 T lymphocytes, but paradoxically also causes general immune activation. Kassiotis and colleagues have mimicked this effect by using genetic engineering to delete activated T cells in mice, and show that in the mice it is due to loss of regulatory T cells.
