Muscle protein metabolism in neonatal alloxan-administered rats: effects of continuous and intermittent swimming training.

In response to glucose overload, rats that had received swimming training were better able to generate an insulin secretory response. Additionally, rats that received continuous training also had an improved glucose tolerance.

Therapeutic ultrasound as a potential male contraceptive: power, frequency and temperature required to deplete rat testes of meiotic cells and epididymides of sperm determined using a commercially available system

Ultrasound has been used in rats to produce a Sperm Count Index of zero. The non-invasive and reversible nature of this treatment makes it a promising candidate for a male contraceptive.

Reversal of type 1 diabetes via islet beta cell regeneration following immune modulation by cord blood-derived multipotent stem cells

The safe reversal of Type 1 diabetes is possible with Stem Cell Educator therapy which uses stem cells from cord blood to re-educate a diabetic's own T cells, restarts pancreatic function, and reduces the need for insulin.

Successful disease-specific induced pluripotent stem cell generation from patients with kidney transplantation

Disease-specific induced pluripotent stem cells (iPSCs) have been generated from kidney transplant recipients, providing opportunities to study patient-specific disease pathogenesis in vitro and demonstrating potential for autologous kidney replacement therapy.

Pharmacogenetics in type 2 diabetes: potential implications for clinical practice

Chunmei Huang and Jose Florez review recent insights into type 2 diabetes that are emerging from pharmacogenetic and pharmacogenomic studies, and discuss the potential for clinical translation.