Welcome to BioMed Central's Endocrinology Gateway, featuring articles from our journals within this field as well as useful resources and news items.
This study examined 18 genes associated with human monogenic diabetes, and tested whether they are also associated with diabetes in 17 different dog breeds. Six variants from five genes were associated with diabetes in some breeds, including two variants in ZFP57 associated with diabetes in two different breeds.
Delphine Fradin and Pierre Bougnères discuss the limitations of a study revealing palmitate-induced epigenetic alterations in pancreatic cells, but emphasize that the findings pave the way for future research into obesity-induced metabolic changes.
Exposing pancreatic islet cells to the free fatty acid palmitate results in differential gene expression and epigenetic modifications, which may influence type 2 diabetes risk through impaired insulin secretion in these treated cells.
In this video Q&A, we interview George Chrousos on the impact of stress on chronic non-communicable disorders, and discuss the physiological and economic factors that affect stress, as well as how it can be prevented.
Five serum proteins can distinguish between serum from women with breast cancer and healthy control subjects with high sensitivity and specificity and can significantly predict recurrence-free survival in women with estrogen receptor negative tumors.
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