Bioinformatics and Genomics Gateway

Welcome to the BioMed Central Bioinformatics and Genomics gateway, highlighting the latest news and information from BioMed Central and from across the web, on Bioinformatics and Genomics.

Articles

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Research article

Efficacy of alogliptin in type 2 diabetes treatment: a meta-analysis of randomized double-blind controlled studies

Berhan A and Berhan Y BMC Endocrine Disorders 2013, 13:9 (1 March 2013)
Research article

Guava leaf extracts promote glucose metabolism in SHRSP.Z-Leprfa/Izm rats by improving insulin resistance in skeletal muscle

Guo X, Yoshitomi H, Gao M, Qin L, Duan Y, Sun W, Xu T, Xie P et al. BMC Complementary and Alternative Medicine 2013, 13:52 (1 March 2013)
Study protocol

Comparison of prasugrel and clopidogrel reloading on high platelet reactivity in clopidogrel-loaded patients undergoing percutaneous coronary intervention (PRAISE-HPR): a study protocol for a prospective randomized controlled clinical trial

Lee DH, Kim MH, Park TH, Park JS, Park K, Zhang HZ, Seo JM and Lee MS Trials 2013, 14:62 (28 February 2013)
Research article

Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study

Cahn A, Hodgson S, Wilson R, Robertson J, Watson J, Beerahee M, Hughes SC, Young G et al. BMC Pharmacology and Toxicology 2013, 14:14 (28 February 2013)
Research article

Bioenergetic study of murine hepatic tissue treated in vitro with atorvastatin

Alfazari AS, Al-Dabbagh B, Almarzooqi S, Albawardi A and Souid AK BMC Pharmacology and Toxicology 2013, 14:15 (28 February 2013)

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News from around the web

01 March 2013: Reprogramming adult cells to stem cells works better with one gene turned off

01 March 2013: 'Defective' virus surprisingly plays major role in spread of disease

01 March 2013: Mechanisms regulating inflammation associated with type 2 diabetes, cancer identified

News and events

Human Genomics has now launched and is accepting submissions

Previously published by Henry Stewart Publications, Human Genomics has now launched and is accepting submissions under BioMed Central's open access platform. Edited by Prof. Vasilis Vasiliou, the journal aims to facilitate rapid publication and stimulate discussion within the human genomic field. The journal welcomes manuscripts relating to the application of genomic analysis in the understanding, treatment and diagnosis of complex and Mendelian diseases, as well as reports of the genomic analysis of adverse drug reactions, drug efficacy and safety.

Submit your manuscript online, and receive updates on this innovative journal's activities and publications by signing up for alerts.

Hot topics

Cancer biomarkers

Unraveling the 'TGF-β paradox' one metastamir at a time

Welch DR and Hurst DR

Breast Cancer Research 2013, 15:305

Metagenomics

Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study

Murri M, Leiva I, Gomez-Zumaquero JM, Cardona F, Soriguer F, Tinahones FJ and Queipo-Ortuno MI

BMC Medicine 2013, 11:46

Clinical proteomics

Proteomics: improving biomarker translation to modern medicine?

Guest PC, Gottschalk MG and Bahn S

Genome Medicine 2013, 5:17

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Bioinformatics and Genomics Gateway

Articles

Efficacy of alogliptin in type 2 diabetes treatment: a meta-analysis of randomized double-blind controlled studies

Guava leaf extracts promote glucose metabolism in SHRSP.Z-Leprfa/Izm rats by improving insulin resistance in skeletal muscle

Comparison of prasugrel and clopidogrel reloading on high platelet reactivity in clopidogrel-loaded patients undergoing percutaneous coronary intervention (PRAISE-HPR): a study protocol for a prospective randomized controlled clinical trial

Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study

Bioenergetic study of murine hepatic tissue treated in vitro with atorvastatin