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				<html:span style="font-weight:bold">This is an RSS newsfeed from BioMed Central</html:span>
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		<title>Current Opinion in Investigational Drugs - Most viewed articles</title>
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		<description>Most viewed articles in last 30 days from Current Opinion in Investigational Drugs (ISSN 1472-4472) published by 
				
				Current Drugs Limited.
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            <title>Apixaban, an oral, direct inhibitor of activated Factor Xa</title>
			<description></description>
			<link>http://www.biomedcentral.com/1472-4472/9/1020</link>		
			<dc:creator>E Shantsila and GYH Lip</dc:creator>
			<dc:source>Current Opinion in Investigational Drugs 2008, 9:1020-1033</dc:source>
			<dc:subject>Number of accesses: 71</dc:subject>
			<dc:date>2008-08-22</dc:date>
			<dc:identifier>doi:10.1186/cd-937523</dc:identifier>
			
			
							
					<prism:publicationName>Current Opinion in Investigational Drugs</prism:publicationName>
					
			
							
					<prism:issn>1472-4472</prism:issn>
					
			
							
					<prism:volume>9</prism:volume>
					
			
							
					<prism:startingPage>1020</prism:startingPage>
					
			
							
					<prism:publicationDate>2008-08-22</prism:publicationDate>
					

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		<item rdf:about="http://www.biomedcentral.com/1472-4472/9/950">
            
            <title>HDL: Still a target for new therapies?</title>
			<description></description>
			<link>http://www.biomedcentral.com/1472-4472/9/950</link>		
			<dc:creator>SJ Nicholls</dc:creator>
			<dc:source>Current Opinion in Investigational Drugs 2008, 9:950-956</dc:source>
			<dc:subject>Number of accesses: 57</dc:subject>
			<dc:date>2008-08-22</dc:date>
			<dc:identifier>doi:10.1186/cd-937508</dc:identifier>
			
			
							
					<prism:publicationName>Current Opinion in Investigational Drugs</prism:publicationName>
					
			
							
					<prism:issn>1472-4472</prism:issn>
					
			
							
					<prism:volume>9</prism:volume>
					
			
							
					<prism:startingPage>950</prism:startingPage>
					
			
							
					<prism:publicationDate>2008-08-22</prism:publicationDate>
					

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		<item rdf:about="http://www.biomedcentral.com/1472-4472/9/402">
            
            <title>Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes</title>
			<description></description>
			<link>http://www.biomedcentral.com/1472-4472/9/402</link>		
			<dc:creator>CF Deacon</dc:creator>
			<dc:source>Current Opinion in Investigational Drugs 2008, 9:402-413</dc:source>
			<dc:subject>Number of accesses: 56</dc:subject>
			<dc:date>2008-04-04</dc:date>
			<dc:identifier>doi:10.1186/cd-893178</dc:identifier>
			
			
							
					<prism:publicationName>Current Opinion in Investigational Drugs</prism:publicationName>
					
			
							
					<prism:issn>1472-4472</prism:issn>
					
			
							
					<prism:volume>9</prism:volume>
					
			
							
					<prism:startingPage>402</prism:startingPage>
					
			
							
					<prism:publicationDate>2008-04-04</prism:publicationDate>
					

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            <title>Non-nucleoside inhibitors of the HCV NS5B polymerase: Progress in the discovery and development of novel agents for the treatment of HCV infections</title>
			<description></description>
			<link>http://www.biomedcentral.com/1472-4472/8/614</link>		
			<dc:creator>PL Beaulieu</dc:creator>
			<dc:source>Current Opinion in Investigational Drugs 2007, 8:614-634</dc:source>
			<dc:subject>Number of accesses: 50</dc:subject>
			<dc:date>2007-07-31</dc:date>
			<dc:identifier>doi:10.1186/cd-817342</dc:identifier>
			
			
							
					<prism:publicationName>Current Opinion in Investigational Drugs</prism:publicationName>
					
			
							
					<prism:issn>1472-4472</prism:issn>
					
			
							
					<prism:volume>8</prism:volume>
					
			
							
					<prism:startingPage>614</prism:startingPage>
					
			
							
					<prism:publicationDate>2007-07-31</prism:publicationDate>
					

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		<item rdf:about="http://www.biomedcentral.com/1472-4472/9/515">
            
            <title>ABT-874, a fully human monoclonal anti-IL-12/IL-23 antibody for
the potential treatment of autoimmune diseases</title>
			<description>ABT-874, a fully human mAb that blocks the binding of IL-12 and IL-23 to their shared IL-12 receptor &#206;&#178;1, is currently being developed by Abbott Laboratories for the potential treatment of Crohn's disease and psoriasis. The compound is currently in phase III clinical trials for psoriasis and phase II trials for Crohn's disease. ABT-87 was previously being developed for the potential treatment of multiple sclerosis; however, by May 2007, development for this indication was discontinued.</description>
			<link>http://www.biomedcentral.com/1472-4472/9/515</link>		
			<dc:creator>C Ding, J Xu and J Li</dc:creator>
			<dc:source>Current Opinion in Investigational Drugs 2008, 9:515-522</dc:source>
			<dc:subject>Number of accesses: 46</dc:subject>
			<dc:date>2008-04-25</dc:date>
			<dc:identifier>doi:10.1186/cd-899624</dc:identifier>
			
			
							
					<prism:publicationName>Current Opinion in Investigational Drugs</prism:publicationName>
					
			
							
					<prism:issn>1472-4472</prism:issn>
					
			
							
					<prism:volume>9</prism:volume>
					
			
							
					<prism:startingPage>515</prism:startingPage>
					
			
							
					<prism:publicationDate>2008-04-25</prism:publicationDate>
					

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            <title>Pulmonary arterial hypertension: On the way to a manageable disease</title>
			<description></description>
			<link>http://www.biomedcentral.com/1472-4472/9/957</link>		
			<dc:creator>HAM Mucke</dc:creator>
			<dc:source>Current Opinion in Investigational Drugs 2008, 9:957-962</dc:source>
			<dc:subject>Number of accesses: 45</dc:subject>
			<dc:date>2008-08-22</dc:date>
			<dc:identifier>doi:10.1186/cd-937509</dc:identifier>
			
			
							
					<prism:publicationName>Current Opinion in Investigational Drugs</prism:publicationName>
					
			
							
					<prism:issn>1472-4472</prism:issn>
					
			
							
					<prism:volume>9</prism:volume>
					
			
							
					<prism:startingPage>957</prism:startingPage>
					
			
							
					<prism:publicationDate>2008-08-22</prism:publicationDate>
					

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		<item rdf:about="http://www.biomedcentral.com/1472-4472/9/945">
            
            <title>The development of novel anti-hyperlipidemic drugs: A tough business gets tougher</title>
			<description></description>
			<link>http://www.biomedcentral.com/1472-4472/9/945</link>		
			<dc:creator>BR Krause</dc:creator>
			<dc:source>Current Opinion in Investigational Drugs 2008, 9:945-949</dc:source>
			<dc:subject>Number of accesses: 37</dc:subject>
			<dc:date>2008-08-22</dc:date>
			<dc:identifier>doi:10.1186/cd-937507</dc:identifier>
			
			
							
					<prism:publicationName>Current Opinion in Investigational Drugs</prism:publicationName>
					
			
							
					<prism:issn>1472-4472</prism:issn>
					
			
							
					<prism:volume>9</prism:volume>
					
			
							
					<prism:startingPage>945</prism:startingPage>
					
			
							
					<prism:publicationDate>2008-08-22</prism:publicationDate>
					

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		<item rdf:about="http://www.biomedcentral.com/1472-4472/9/614">
            
            <title>Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors</title>
			<description></description>
			<link>http://www.biomedcentral.com/1472-4472/9/614</link>		
			<dc:creator>JA McCubrey, M Milella, A Tafuri, AM Martelli, P Lunghi, A Bonati, M Cervello, JT Lee and LS Steelman</dc:creator>
			<dc:source>Current Opinion in Investigational Drugs 2008, 9:614-630</dc:source>
			<dc:subject>Number of accesses: 34</dc:subject>
			<dc:date>2008-05-28</dc:date>
			<dc:identifier>doi:10.1186/cd-910547</dc:identifier>
			
			
							
					<prism:publicationName>Current Opinion in Investigational Drugs</prism:publicationName>
					
			
							
					<prism:issn>1472-4472</prism:issn>
					
			
							
					<prism:volume>9</prism:volume>
					
			
							
					<prism:startingPage>614</prism:startingPage>
					
			
							
					<prism:publicationDate>2008-05-28</prism:publicationDate>
					

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		<item rdf:about="http://www.biomedcentral.com/1472-4472/9/885">
            
            <title>Raltegravir, an HIV-1 integrase inhibitor for HIV infection</title>
			<description></description>
			<link>http://www.biomedcentral.com/1472-4472/9/885</link>		
			<dc:creator>C Cabrera</dc:creator>
			<dc:source>Current Opinion in Investigational Drugs 2008, 9:885-898</dc:source>
			<dc:subject>Number of accesses: 29</dc:subject>
			<dc:date>2008-07-25</dc:date>
			<dc:identifier>doi:10.1186/cd-928098</dc:identifier>
			
			
							
					<prism:publicationName>Current Opinion in Investigational Drugs</prism:publicationName>
					
			
							
					<prism:issn>1472-4472</prism:issn>
					
			
							
					<prism:volume>9</prism:volume>
					
			
							
					<prism:startingPage>885</prism:startingPage>
					
			
							
					<prism:publicationDate>2008-07-25</prism:publicationDate>
					

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		<item rdf:about="http://www.biomedcentral.com/1472-4472/9/371">
            
            <title>Sirtuins: Novel targets for metabolic disease</title>
			<description></description>
			<link>http://www.biomedcentral.com/1472-4472/9/371</link>		
			<dc:creator>PJ Elliott and M Jirousek</dc:creator>
			<dc:source>Current Opinion in Investigational Drugs 2008, 9:371-378</dc:source>
			<dc:subject>Number of accesses: 28</dc:subject>
			<dc:date>2008-04-04</dc:date>
			<dc:identifier>doi:10.1186/cd-893173</dc:identifier>
			
			
							
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					<prism:volume>9</prism:volume>
					
			
							
					<prism:startingPage>371</prism:startingPage>
					
			
							
					<prism:publicationDate>2008-04-04</prism:publicationDate>
					

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