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Current Opinion in Drug Discovery & Development

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BMC  Current Opinion in Drug Discovery & Development, Volume 12


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Paper alert
P Norman, DP Rotella, B Sherborne
Current Opinion in Drug Discovery and Development 2009, 12:1-15 (15January2009)
[Abstract] [Full text] [PDF]


Patent alert
Reuters Current Awareness Analysts Thomson
Current Opinion in Drug Discovery and Development 2009, 12:16-23 (15January2009)
[Abstract] [Full text] [PDF]


Web alert
TDY Chung
Current Opinion in Drug Discovery and Development 2009, 12:24-26 (15January2009)
[Abstract] [Full text] [PDF]


Pharmacogenomics and adverse drug reactions; prospective screening for risk identification
DE Johnson, DA Smith, BK Park
Current Opinion in Drug Discovery and Development 2009, 12:27-30 (15January2009)
[Abstract] [Full text] [PDF]


The role of binding kinetics in therapeutically useful drug action
DC Swinney
Current Opinion in Drug Discovery and Development 2009, 12:31-39 (15January2009)
[Abstract] [Full text] [PDF]


Metabolomics in pharmaceutical research and development: Metabolites, mechanisms and pathways
EY Xu, WH Schaefer, Q Xu
Current Opinion in Drug Discovery and Development 2009, 12:40-52 (15January2009)
[Abstract] [Full text] [PDF]


Current HIV therapeutics: Mechanistic and chemical determinants of toxicity
S Chiao, DL Romero, DE Johnson
Current Opinion in Drug Discovery and Development 2009, 12:53-60 (15January2009)
[Abstract] [Full text] [PDF]


Does human pharmacokinetic prediction add significant value to compound selection in drug discovery research?
K Beaumont, DA Smith
Current Opinion in Drug Discovery and Development 2009, 12:61-71 (15January2009)
[Abstract] [Full text] [PDF]


Novel genomic methods for drug discovery and mechanism-based toxicological assessment
TW Gant, S-D Zhang, EL Taylor
Current Opinion in Drug Discovery and Development 2009, 12:72-80 (15January2009)
[Abstract] [Full text] [PDF]


Predicting drug-drug interactions from in vitro drug metabolism data: Challenges and recent advances
RS Obach
Current Opinion in Drug Discovery and Development 2009, 12:81-89 (15January2009)
[Abstract] [Full text] [PDF]


Early toxicity screening strategies
N Greene, R Naven
Current Opinion in Drug Discovery and Development 2009, 12:90-97 (15January2009)
[Abstract] [Full text] [PDF]


Clustering and its application in multi-target prediction
W Liu, DE Johnson
Current Opinion in Drug Discovery and Development 2009, 12:98-107 (15January2009)
[Abstract] [Full text] [PDF]


CYP2C9 polymorphisms: Considerations in NSAID therapy
ZK Ali, RJ Kim, FM Ysla
Current Opinion in Drug Discovery and Development 2009, 12:108-114 (15January2009)
[Abstract] [Full text] [PDF]


Current in vitro and in silico models of blood-brain barrier penetration: A practical view
M Vastag, GM Keser
Current Opinion in Drug Discovery and Development 2009, 12:115-124 (15January2009)
[Abstract] [Full text] [PDF]


The role of bioactivation in the pharmacology and toxicology of the artemisinin-based antimalarials
AE Mercer
Current Opinion in Drug Discovery and Development 2009, 12:125-132 (15January2009)
[Abstract] [Full text] [PDF]


Cardiomyocytes derived from human embryonic stem cells characteristics and utility for drug discovery
D Steel, J Hyllner, P Sartipy
Current Opinion in Drug Discovery and Development 2009, 12:133-140 (15January2009)
[Abstract] [Full text] [PDF]


Chemical and molecular basis of the carcinogenicity of Aristolochia plants
HH Schmeiser, M Stiborov, VM Arlt
Current Opinion in Drug Discovery and Development 2009, 12:141-148 (15January2009)
[Abstract] [Full text] [PDF]


The ABCs of human alternative splicing: A review of ATP-binding cassette transporter splicing
S Srinivasan, JL Bingham, D Johnson
Current Opinion in Drug Discovery and Development 2009, 12:149-158 (15January2009)
[Abstract] [Full text] [PDF]


Paper alert
P Norman, DP Rotella, B Sherborne
Current Opinion in Drug Discovery and Development 2009, 12:159-173 (2March2009)
[Abstract] [Full text] [PDF]


Patent alert
Reuters Current Awareness Analysts Thomson
Current Opinion in Drug Discovery and Development 2009, 12:174-181 (2March2009)
[Abstract] [Full text] [PDF]



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