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Current Opinion in Drug Discovery & Development, Volume 11, Issue 4 (July 2008)        [more info]

 
Current Opinion in Drug Discovery & Development is published bimonthly and focuses on the chemical aspects of drug discovery and development.

Access to the full text or PDF of articles from Current Opinion in Drug Discovery & Development requires a subscription to the journal.


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Paper alert
Paper alert
P Norman, DP Rotella, B Sherborne
Current Opinion in Drug Discovery and Development 2008, 11:407-420 (30June2008)
[PDF]

Patent alert
Patent alert
Reuters Current Awareness Analysts Thomson
Current Opinion in Drug Discovery and Development 2008, 11:421-433 (30June2008)
[PDF]

Web alert
Web alert
TDY Chung
Current Opinion in Drug Discovery and Development 2008, 11:434-435 (30June2008)
[PDF]

Review
Rediscovering the role of natural products in drug discovery
MC Desai, S Chackalamannil
Current Opinion in Drug Discovery and Development 2008, 11:436-437 (30June2008)
[PDF] [PubMed] [Related articles]

Review
Agonists of the serotonin 5-HT2C receptor: Preclinical and clinical progression in multiple diseases
DA Wacker, KJ Miller
Current Opinion in Drug Discovery and Development 2008, 11:438-445 (30June2008)
[PDF] [PubMed] [Related articles]

Review
Recent progress in the discovery of selective, non-peptide ligands of somatostatin receptors
SE Wolkenberg, CJ Thut
Current Opinion in Drug Discovery and Development 2008, 11:446-457 (30June2008)
[PDF] [PubMed] [Related articles]

Review
Improving non-nucleoside reverse transcriptase inhibitors for first-line treatment of HIV infection: The development pipeline and recent clinical data
ZK Sweeney, K Klumpp
Current Opinion in Drug Discovery and Development 2008, 11:458-470 (30June2008)
[PDF] [PubMed] [Related articles]

Review
Integrase inhibitors for the treatment of HIV infection
P Pace, M Rowley
Current Opinion in Drug Discovery and Development 2008, 11:471-479 (30June2008)
[PDF] [PubMed] [Related articles]

Review
TAFIa inhibitors in the treatment of thrombosis
ME Bunnage, DR Owen
Current Opinion in Drug Discovery and Development 2008, 11:480-486 (30June2008)
[PDF] [PubMed] [Related articles]

Review
Targeting myostatin for therapies against muscle-wasting disorders
K Tsuchida
Current Opinion in Drug Discovery and Development 2008, 11:487-494 (30June2008)
[PDF] [PubMed] [Related articles]

Review
Recent advances in the discovery of 11b-HSD1 inhibitors
CD Boyle
Current Opinion in Drug Discovery and Development 2008, 11:495-511 (30June2008)
[PDF] [PubMed] [Related articles]

Review
From the bench to the bedside: Dipeptidyl peptidase IV inhibitors, a new class of oral antihyperglycemic agents
Z Pei
Current Opinion in Drug Discovery and Development 2008, 11:512-532 (30June2008)
[PDF] [PubMed] [Related articles]

Review
Glycogen synthase kinase-3 (GSK-3) inhibitors reach the clinic
M Medina, A Castro
Current Opinion in Drug Discovery and Development 2008, 11:533-543 (30June2008)
[PDF] [PubMed] [Related articles]

Review
Conformationally based design of macrocycles as antitumor agents
EK Singh, RP Sellers, LD Alexander, SR McAlpine
Current Opinion in Drug Discovery and Development 2008, 11:544-552 (30June2008)
[PDF] [PubMed] [Related articles]

Review
The impact of diversity-based, high-throughput screening on drug discovery: "Chance favours the prepared mind"
M Snowden, DVS Green
Current Opinion in Drug Discovery and Development 2008, 11:553-558 (30June2008)
[PDF] [PubMed] [Related articles]

Review
From virtuality to reality Virtual screening in lead discovery and lead optimization: A medicinal chemistry perspective
U Rester
Current Opinion in Drug Discovery and Development 2008, 11:559-568 (30June2008)
[PDF] [PubMed] [Related articles]

Review
Exploiting QSAR models in lead optimization
P Gedeck, RA Lewis
Current Opinion in Drug Discovery and Development 2008, 11:569-575 (30June2008)
[PDF] [PubMed] [Related articles]

 

 

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