Bozdech - Spellman co-coexpression analysis

36 cluster pairs

Cluster Pair #0: 4 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PFL2440w ?
DNA repair protein rhp16, putative

repairosome ?
ubiquitin ligase complex (IEA) ?
nucleic acid binding (IEA) ?
DNA binding (IEA) ?
helicase activity (IEA) ?
ubiquitin-protein ligase activity (IEA) ?
ATP binding ?
nucleus (IEA) ?
nucleotide-excision repair ?
ATP-dependent helicase activity ?
zinc ion binding (IEA) ?
protein ubiquitination (IEA) ?
YBR114W ?
repairosome ?
nucleotide excision repair factor 4 complex ?
nucleotide-excision repair, DNA damage recognition ?
damaged DNA binding ?
DNA-dependent ATPase activity ?
0

BLAST
PF10_0310 ?
hypothetical protein

YHR156C ?
chromatin ?
protein binding ?
nucleus ?
snRNP U5 ?
4e-09

BLAST
PFA0580c ?
TatD-like deoxyribonuclease, putative

deoxyribonuclease activity ?
DNA metabolism ?
apicoplast ?
YBL055C ?
endonuclease activity ?
cytoplasm ?
DNA fragmentation during apoptosis ?
response to oxidative stress ?
3'-5'-exodeoxyribonuclease activity ?
6e-38

BLAST
PFC0785c ?
proteasome regulatory protein, putative

protein binding (IEA) ?
proteasome regulatory particle (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
YIL007C ?
cytoplasm ?
ubiquitin-dependent protein catabolism ?
2e-14

BLAST

Cluster Pair #1: 10 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF14_0663 ?
hypothetical protein

metalloendopeptidase activity (IEA) ?
proteolysis and peptidolysis (IEA) ?
pathogenesis (IEA) ?
metal ion binding (IEA) ?
YDL167C ?
cytoplasm ?
ribosome biogenesis and assembly ?
3e-05

BLAST
PFI1060w ?
hypothetical protein

YDL189W ?
cytoplasm ?
galactose metabolism ?
0.016

BLAST
PF13_0278 ?
hypothetical protein

nucleic acid binding (IEA) ?
YDL167C ?
cytoplasm ?
ribosome biogenesis and assembly ?
5e-05

BLAST
MAL8P1.67 ?
hypothetical protein, conserved

YDR339C ?
nucleolus ?
35S primary transcript processing ?
mitochondrion organization and biogenesis ?
0

BLAST
PF10_0123 ?
GMP synthetase

catalytic activity (IEA) ?
GMP synthase activity ?
GMP synthase (glutamine-hydrolyzing) activity (IEA) ?
ATP binding (IEA) ?
purine nucleotide biosynthesis ?
GMP biosynthesis (IEA) ?
glutamine metabolism (IEA) ?
YMR217W ?
GMP synthase (glutamine-hydrolyzing) activity ?
GMP metabolism ?
0

BLAST
PFI0415c ?
ribosomal RNA methyltransferase, putative

YBR061C ?
cytoplasm ?
protein biosynthesis ?
tRNA methyltransferase activity ?
tRNA methylation ?
6.00036e-42

BLAST
PFE0885w ?
eukaryotic translation initiation factor 3 subunit, putative

nucleic acid binding (IEA) ?
YOR361C ?
translation initiation factor activity ?
cytoplasm ?
eukaryotic translation initiation factor 3 complex ?
translational initiation ?
0

BLAST
PFB0375w ?
hypothetical protein

metalloendopeptidase activity (IEA) ?
proteolysis and peptidolysis (IEA) ?
pathogenesis (IEA) ?
membrane ?
metal ion binding (IEA) ?
YDL167C ?
cytoplasm ?
ribosome biogenesis and assembly ?
0.0004

BLAST
PF10_0197 ?
hypothetical protein

apicoplast ?
YNL022C ?
nucleus ?
ribosome biogenesis and assembly ?
9e-06

BLAST
PFL0335c ?
eukaryotic translation initiation factor 5, putative

translation initiation factor activity ?
translational initiation (IEA) ?
regulation of translational initiation ?
YPR041W ?
translation initiation factor activity ?
GTPase activator activity ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
regulation of translational initiation ?
mature ribosome assembly ?
6e-33

BLAST

Cluster Pair #2: 9 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF10_0300 ?
hypothetical protein, conserved

RNA binding (IEA) ?
RNA processing (IEA) ?
RNA methyltransferase activity (IEA) ?
YDL112W ?
cytoplasm ?
tRNA (guanosine) methyltransferase activity ?
tRNA methylation ?
0.002

BLAST
MAL13P1.170 ?
hypothetical protein

nucleic acid binding (IEA) ?
nucleotidyltransferase activity (IEA) ?
YNL299W ?
DNA-directed DNA polymerase activity ?
polynucleotide adenylyltransferase activity ?
nucleus ?
nucleolus ?
mitotic sister chromatid cohesion ?
rRNA catabolism ?
snRNA catabolism ?
snoRNA catabolism ?
5e-19

BLAST
PF11_0316 ?
hypothetical protein

YOL125W ?
nucleus ?
cytoplasm ?
tRNA methyltransferase activity ?
tRNA methylation ?
2e-06

BLAST
PFA0480w ?
phenylalanyl-tRNA synthetase beta chain, putative

tRNA ligase activity (IEA) ?
phenylalanine-tRNA ligase activity ?
ATP binding (IEA) ?
cytoplasm (IEA) ?
tRNA aminoacylation for protein translation (IEA) ?
phenylalanyl-tRNA aminoacylation ?
phenylalanine-tRNA ligase complex ?
YFL022C ?
phenylalanine-tRNA ligase activity ?
cytoplasm ?
phenylalanyl-tRNA aminoacylation ?
phenylalanine-tRNA ligase complex ?
0

BLAST
PFI0700c ?
Met-10+ like protein, putative

apicoplast ?
YHR070W ?
nucleus ?
cytoplasm ?
tRNA (guanine) methyltransferase activity ?
tRNA methylation ?
ribosome biogenesis and assembly ?
1e-19

BLAST
MAL13P1.36 ?
hypothetical protein, conserved

nucleic acid binding (IEA) ?
YOL142W ?
3'-5'-exoribonuclease activity ?
nuclear exosome (RNase complex) ?
cytoplasmic exosome (RNase complex) ?
RNA binding ?
35S primary transcript processing ?
mRNA catabolism ?
ribosome assembly ?
3e-11

BLAST
PF13_0354 ?
alanine--tRNA ligase, putative

alanine-tRNA ligase activity ?
ATP binding (IEA) ?
alanyl-tRNA aminoacylation ?
apicoplast ?
YOR335C ?
alanine-tRNA ligase activity ?
cytoplasm ?
mitochondrion ?
alanyl-tRNA aminoacylation ?
0

BLAST
PF14_0620 ?
hypothetical protein

YKR079C ?
nucleus ?
cytoplasm ?
mitochondrion ?
purine nucleotide binding ?
removal of tRNA 3'-trailer sequence ?
3'-tRNA processing endoribonuclease activity ?
9e-23

BLAST
MAL7P1.28 ?
hypothetical protein

tRNA 5'-leader removal (IEA) ?
ribonuclease P activity (IEA) ?
YNL221C ?
ribonuclease MRP activity ?
ribonuclease MRP complex ?
ribonuclease P activity ?
nucleolar ribonuclease P complex ?
rRNA processing ?
tRNA processing ?
0.014

BLAST

Cluster Pair #3: 8 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF11_0445 ?
DNA-directed RNA polymerase I, putative

DNA binding (IEA) ?
DNA-directed RNA polymerase activity (IEA) ?
transcription (IEA) ?
protein dimerization activity (IEA) ?
YPR110C ?
DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase III complex ?
DNA-directed RNA polymerase I complex ?
transcription from RNA polymerase I promoter ?
transcription from RNA polymerase III promoter ?
ribosome biogenesis and assembly ?
9.94922e-44

BLAST
PF11_0439 ?
hypothetical protein

YPL239W ?
cytoplasm ?
response to osmotic stress ?
response to oxidative stress ?
ribosomal small subunit biogenesis ?
0.003

BLAST
PF14_0072 ?
hypothetical protein, conserved

YNR046W ?
tRNA (guanine-N2-)-methyltransferase activity ?
nucleus ?
nucleolus ?
cytoplasm ?
zinc ion binding ?
tRNA methylation ?
2e-09

BLAST
PFI1235w ?
hypothetical protein

YDR083W ?
telomere maintenance ?
nucleolus ?
rRNA processing ?
methyltransferase activity ?
ribosome biogenesis and assembly ?
6e-24

BLAST
PF10_0209 ?
RNA helicase, putative

nucleic acid binding (IEA) ?
RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YGL171W ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
ATPase activity ?
2e-36

BLAST
PFB0826c ?
hypothetical protein

** also with: YPL146C, clust.pair #3
YPR143W ?
nucleus ?
nucleolus ?
processing of 27S pre-rRNA ?
ribosome biogenesis and assembly ?
0.029

BLAST
PFB0826c ?
hypothetical protein

** also with: YPR143W, clust.pair #3
YPL146C ?
ribosomal large subunit-nucleus export ?
nucleus ?
nucleolus ?
rRNA binding ?
processing of 27S pre-rRNA ?
ribosome biogenesis and assembly ?
0.05

BLAST
PF08_0123 ?
hypothetical protein

YPL212C ?
nucleus ?
tRNA modification ?
tRNA-pseudouridine synthase activity ?
ribosome biogenesis and assembly ?
2e-17

BLAST

Cluster Pair #4: 8 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF14_0207 ?
RNA polymerase subunit, putative

DNA binding (IEA) ?
DNA-directed RNA polymerase activity ?
nucleus (IEA) ?
transcription (IEA) ?
regulation of transcription, DNA-dependent ?
membrane ?
YNR003C ?
DNA-directed RNA polymerase activity ?
nucleus ?
DNA-directed RNA polymerase III complex ?
cytoplasm ?
transcription from RNA polymerase III promoter ?
ribosome biogenesis and assembly ?
3e-11

BLAST
PF10_0150 ?
methionine aminopeptidase, putative

methionyl aminopeptidase activity ?
regulation of protein biosynthesis ?
regulation of translation ?
protein modification ?
proteolysis and peptidolysis ?
metalloexopeptidase activity (IEA) ?
YLR244C ?
methionyl aminopeptidase activity ?
cytosolic ribosome (sensu Eukaryota) ?
proteolysis and peptidolysis ?
0

BLAST
PFE0730c ?
ribose 5-phosphate epimerase, putative

ribose-5-phosphate isomerase activity ?
pentose-phosphate shunt, non-oxidative branch ?
YOR095C ?
ribose-5-phosphate isomerase activity ?
nucleus ?
cytoplasm ?
pentose-phosphate shunt ?
pyridoxine biosynthesis ?
ribosome biogenesis and assembly ?
2e-25

BLAST
PF11_0101 ?
hypothetical protein

YBR155W ?
cytoplasm ?
protein folding ?
Hsp70 protein binding ?
0.025

BLAST
PFC0350c ?
T-complex protein eta subunit, putative

protein binding (IEA) ?
ATP binding (IEA) ?
chaperonin-containing T-complex ?
protein folding ?
cellular protein metabolism (IEA) ?
unfolded protein binding ?
YJL111W ?
cytoplasm ?
chaperonin-containing T-complex ?
cytoskeleton ?
protein folding ?
cytoskeleton organization and biogenesis ?
unfolded protein binding ?
0

BLAST
PFE1370w ?
hsp70 interacting protein, putative

YBR155W ?
cytoplasm ?
protein folding ?
Hsp70 protein binding ?
1e-06

BLAST
PF13_0205 ?
tryptophan--tRNA ligase, putative

tRNA ligase activity (IEA) ?
tryptophan-tRNA ligase activity ?
ATP binding (IEA) ?
tRNA aminoacylation for protein translation (IEA) ?
tryptophanyl-tRNA aminoacylation ?
apicoplast ?
YOL097C ?
tryptophan-tRNA ligase activity ?
cytoplasm ?
tryptophanyl-tRNA aminoacylation ?
0

BLAST
PFL2150c ?
hypothetical protein, conserved

YOR091W ?
cytoplasm ?
ribosome ?
ribosome biogenesis and assembly ?
3e-36

BLAST

Cluster Pair #5: 9 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PFL0670c ?
Bi-functional aminoacyl-tRNA synthetase, putative

tRNA ligase activity (IEA) ?
glutamate-tRNA ligase activity ?
proline-tRNA ligase activity ?
ATP binding (IEA) ?
cytoplasm (IEA) ?
protein biosynthesis (IEA) ?
tRNA aminoacylation for protein translation ?
prolyl-tRNA aminoacylation (IEA) ?
YHR020W ?
proline-tRNA ligase activity ?
ribosome ?
tRNA aminoacylation for protein translation ?
0

BLAST
PF14_0486 ?
elongation factor 2

translation elongation factor activity ?
GTP binding ?
protein biosynthesis (IEA) ?
translational elongation ?
** also with: YOR133W, clust.pair #5
YDR385W ?
translation elongation factor activity ?
ribosome ?
translational elongation ?
0

BLAST
PF14_0486 ?
elongation factor 2

translation elongation factor activity ?
GTP binding ?
protein biosynthesis (IEA) ?
translational elongation ?
** also with: YDR385W, clust.pair #5
YOR133W ?
translation elongation factor activity ?
ribosome ?
translational elongation ?
0

BLAST
PF14_0028 ?
hypothetical protein, conserved

nucleic acid binding (IEA) ?
RNA binding (IEA) ?
RNA processing (IEA) ?
ATP biosynthesis (IEA) ?
ATP synthesis coupled proton transport (IEA) ?
proton-transporting two-sector ATPase complex (IEA) ?
hydrogen-transporting ATP synthase activity, rotational mechanism (IEA) ?
hydrogen-transporting ATPase activity, rotational mechanism (IEA) ?
YER165W ?
nucleus ?
cytoplasm ?
ribosome ?
regulation of translational initiation ?
poly(A) binding ?
6e-06

BLAST
PF11_0116 ?
hypothetical protein

YBL024W ?
nucleus ?
tRNA (cytosine-5-)-methyltransferase activity ?
tRNA methylation ?
ribosome biogenesis and assembly ?
2e-09

BLAST
PFB0550w ?
peptide chain release factor subunit 1, putative

translation release factor activity ?
cytoplasm (IEA) ?
translational termination (IEA) ?
regulation of translational termination ?
translation release factor activity, codon specific (IEA) ?
YBR143C ?
cytokinesis ?
cytosol ?
translational termination ?
translation release factor activity, codon specific ?
translation release factor complex ?
0

BLAST
PFE0845c ?
60S ribosomal subunit protein L8, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
YIL018W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
response to drug ?
0

BLAST
PF07_0015 ?
hypothetical protein

metalloendopeptidase activity (IEA) ?
proteolysis and peptidolysis (IEA) ?
pathogenesis (IEA) ?
metal ion binding (IEA) ?
YBL024W ?
nucleus ?
tRNA (cytosine-5-)-methyltransferase activity ?
tRNA methylation ?
ribosome biogenesis and assembly ?
3e-39

BLAST
PF14_0198 ?
glycine -- tRNA ligase, putative

tRNA ligase activity (IEA) ?
glycine-tRNA ligase activity ?
ATP binding (IEA) ?
protein biosynthesis (IEA) ?
tRNA aminoacylation for protein translation (IEA) ?
glycyl-tRNA aminoacylation ?
apicoplast ?
YBR121C ?
glycine-tRNA ligase activity ?
cytoplasm ?
mitochondrion ?
transcription termination ?
glycyl-tRNA aminoacylation ?
0

BLAST

Cluster Pair #6: 7 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
MAL8P1.142 ?
proteasome beta-subunit

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism (IEA) ?
YFR050C ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
proteasome core complex, beta-subunit complex (sensu Eukaryota) ?
5e-26

BLAST
PFC0520w ?
26S proteasome regulatory subunit S14, putative

proteasome regulatory particle (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
YFR052W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, lid subcomplex (sensu Eukaryota) ?
4e-14

BLAST
PF14_0178 ?
hypothetical protein

ubiquitin-dependent protein catabolism (IEA) ?
membrane ?
YGR048W ?
protein binding ?
endoplasmic reticulum ?
mRNA processing ?
ubiquitin-dependent protein catabolism ?
protein transport ?
7e-34

BLAST
PF14_0025 ?
proteosome subunit, putative

endopeptidase activity ?
proteasome regulatory particle (sensu Eukaryota) ?
proteolysis and peptidolysis ?
YDL097C ?
structural molecule activity ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, lid subcomplex (sensu Eukaryota) ?
8e-21

BLAST
PF08_0071 ?
Fe-superoxide dismutase

superoxide dismutase activity (IEA) ?
superoxide metabolism ?
response to oxidative stress ?
iron superoxide dismutase activity ?
metal ion binding (IEA) ?
YHR008C ?
replicative cell aging ?
age-dependent response to reactive oxygen species during chronological cell aging ?
age-dependent response to oxidative stress during chronological cell aging ?
mitochondrion ?
mitochondrial matrix ?
oxygen and reactive oxygen species metabolism ?
manganese superoxide dismutase activity ?
6e-30

BLAST
PFL2415w ?
Hbeta58%2FVps26 protein homolog, putative

intracellular protein transport (IEA) ?
retrograde transport, endosome to Golgi ?
YJL053W ?
endosome ?
protein transporter activity ?
retromer complex ?
retrograde transport, endosome to Golgi ?
protein retention in Golgi ?
0

BLAST
MAL8P1.128 ?
proteasome subunit alpha, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
YGL011C ?
endopeptidase activity ?
mitochondrion ?
ubiquitin-dependent protein catabolism ?
proteasome core complex, alpha-subunit complex (sensu Eukaryota) ?
1e-34

BLAST

Cluster Pair #7: 5 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF13_0182 ?
hypothetical protein

catalytic activity (IEA) ?
ubiquitin activating enzyme activity (IEA) ?
protein modification (IEA) ?
ubiquitin cycle (IEA) ?
small protein activating enzyme activity (IEA) ?
membrane ?
apicoplast ?
YKL210W ?
ubiquitin activating enzyme activity ?
nucleus ?
cytoplasm ?
ubiquitin cycle ?
9e-20

BLAST
PFA0400c ?
beta3 proteasome subunit, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
YER094C ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
proteasome core complex, beta-subunit complex (sensu Eukaryota) ?
0

BLAST
PF07_0112 ?
proteasome subunit alpha type 5, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex (sensu Eukaryota) (IEA) ?
ubiquitin-dependent protein catabolism ?
proteasome core complex, alpha-subunit complex (sensu Eukaryota) ?
YGR253C ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
response to stress ?
proteasome core complex, alpha-subunit complex (sensu Eukaryota) ?
sporulation (sensu Fungi) ?
0

BLAST
PFE0915c ?
proteasome subunit beta type 1

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
YBL041W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
proteasome core complex, beta-subunit complex (sensu Eukaryota) ?
9e-35

BLAST
PF13_0282 ?
proteasome subunit, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
YGR135W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
proteasome core complex, alpha-subunit complex (sensu Eukaryota) ?
filamentous growth ?
0

BLAST

Cluster Pair #8: 6 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PFI0155c ?
ras family GTP-ase, putative

GTP binding (IEA) ?
intracellular protein transport (IEA) ?
small GTPase mediated signal transduction (IEA) ?
protein transport (IEA) ?
YML001W ?
vacuole inheritance ?
telomere maintenance ?
GTPase activity ?
mitochondrial outer membrane ?
vacuole ?
Golgi to vacuole transport ?
endocytosis ?
vesicle-mediated transport ?
vacuole fusion, non-autophagic ?
0

BLAST
PF10_0174 ?
26s proteasome subunit p55, putative

endopeptidase activity ?
proteasome regulatory particle (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
YDL147W ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, lid subcomplex (sensu Eukaryota) ?
0

BLAST
PF14_0493 ?
sortilin, putative

lipid transporter activity ?
intracellular protein transport (IEA) ?
endocytosis ?
protein transporter activity (IEA) ?
membrane ?
YNR065C ?
0

BLAST
PFC0745c ?
proteasome component C8, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
YOR362C ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
proteasome core complex, alpha-subunit complex (sensu Eukaryota) ?
1e-32

BLAST
PF11_0184 ?
DNA mismatch repair protein MLH1, putative

ATP binding ?
mismatch repair ?
ATPase activity ?
YMR167W ?
meiotic mismatch repair ?
DNA binding ?
ATP binding ?
nucleus ?
mitochondrion ?
meiotic recombination ?
ATPase activity ?
0

BLAST
PFC0845c ?
ubiquitin--protein ligase, putative

ubiquitin ligase complex ?
ubiquitin-protein ligase activity ?
ubiquitin-dependent protein catabolism ?
zinc ion binding (IEA) ?
protein ubiquitination (IEA) ?
apicoplast ?
YOL133W ?
G1/S transition of mitotic cell cycle ?
G2/M transition of mitotic cell cycle ?
nuclear ubiquitin ligase complex ?
ubiquitin-protein ligase activity ?
protein binding ?
nucleus ?
cytoplasm ?
protein ubiquitination ?
SCF ubiquitin ligase complex ?
SCF-dependent proteasomal ubiquitin-dependent protein catabolism ?
9e-34

BLAST

Cluster Pair #9: 4 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF10_0081 ?
26S proteasome regulatory subunit 4, putative

nucleotide binding (IEA) ?
endopeptidase activity ?
ATP binding (IEA) ?
nucleus (IEA) ?
cytoplasm (IEA) ?
proteasome regulatory particle (sensu Eukaryota) ?
proteolysis and peptidolysis ?
hydrolase activity (IEA) ?
ATPase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
protein catabolism (IEA) ?
YDL007W ?
endopeptidase activity ?
nucleus ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, base subcomplex (sensu Eukaryota) ?
ATPase activity ?
0

BLAST
PF11_0314 ?
26S protease subunit regulatory subunit 6a, putative

nucleotide binding (IEA) ?
proteasome complex (sensu Eukaryota) ?
endopeptidase activity ?
ATP binding (IEA) ?
nucleus (IEA) ?
cytoplasm (IEA) ?
proteolysis and peptidolysis ?
hydrolase activity (IEA) ?
ATPase activity ?
nucleoside-triphosphatase activity (IEA) ?
protein catabolism (IEA) ?
YOR117W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, base subcomplex (sensu Eukaryota) ?
ATPase activity ?
0

BLAST
PF14_0632 ?
26S proteasome subunit, putative

regulation of progression through cell cycle (IEA) ?
endopeptidase activity ?
proteasome regulatory particle (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
YIL075C ?
endopeptidase activity ?
nucleus ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, base subcomplex (sensu Eukaryota) ?
protein binding, bridging ?
0

BLAST
MAL13P1.343 ?
proteasome regulatory subunit, putative

proteasome regulatory particle (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
YFR004W ?
endopeptidase activity ?
nucleus ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, lid subcomplex (sensu Eukaryota) ?
0

BLAST

Cluster Pair #10: 4 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PFD0665c ?
26s proteasome aaa-ATPase subunit Rpt3, putative

nucleotide binding (IEA) ?
ATP binding (IEA) ?
nucleus (IEA) ?
cytoplasm (IEA) ?
proteasome regulatory particle (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
hydrolase activity (IEA) ?
ATPase activity ?
nucleoside-triphosphatase activity (IEA) ?
protein catabolism (IEA) ?
YDR394W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, base subcomplex (sensu Eukaryota) ?
ATPase activity ?
0

BLAST
PF08_0109 ?
hypothetical protein

YHR200W ?
proteasome complex (sensu Eukaryota) ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, base subcomplex (sensu Eukaryota) ?
2e-29

BLAST
PF13_0063 ?
26S proteasome regulatory subunit 7, putative

nucleotide binding (IEA) ?
endopeptidase activity ?
ATP binding (IEA) ?
nucleus (IEA) ?
cytoplasm (IEA) ?
proteasome regulatory particle (sensu Eukaryota) ?
ubiquitin-dependent protein catabolism ?
hydrolase activity (IEA) ?
ATPase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
protein catabolism (IEA) ?
YKL145W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, base subcomplex (sensu Eukaryota) ?
ATPase activity ?
0

BLAST
PFL2345c ?
tat-binding protein homolog

nucleotide binding (IEA) ?
proteasome complex (sensu Eukaryota) ?
transcription cofactor activity ?
ATP binding (IEA) ?
nucleus (IEA) ?
cytoplasm (IEA) ?
ubiquitin-dependent protein catabolism ?
hydrolase activity (IEA) ?
ATPase activity ?
nucleoside-triphosphatase activity (IEA) ?
nucleotide kinase activity (IEA) ?
protein catabolism (IEA) ?
YGL048C ?
endopeptidase activity ?
nucleus ?
ubiquitin-dependent protein catabolism ?
proteasome regulatory particle, base subcomplex (sensu Eukaryota) ?
ATPase activity ?
0

BLAST

Cluster Pair #11: 5 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF11_0105 ?
hypothetical protein

YBR247C ?
nucleus ?
nucleolus ?
rRNA processing ?
35S primary transcript processing ?
snoRNA binding ?
nucleolar preribosome, small subunit precursor ?
ribosome biogenesis and assembly ?
1e-37

BLAST
PF14_0136 ?
hypothetical protein, conserved

YIL103W ?
cytoplasm ?
peptidyl-diphthamide biosynthesis from peptidyl-histidine ?
0

BLAST
PF14_0183 ?
RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YJL033W ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
0

BLAST
PFI0815c ?
hypothetical protein, conserved

S-adenosylmethionine-dependent methyltransferase activity (IEA) ?
YIL064W ?
cytoplasm ?
S-adenosylmethionine-dependent methyltransferase activity ?
ribosome biogenesis and assembly ?
1e-16

BLAST
PF08_0041 ?
ribosome biogenesis protein nep1 homologue, putative

nucleus (IEA) ?
ribosome biogenesis ?
ribosome biogenesis and assembly (IEA) ?
YLR186W ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
cytoplasm ?
nuclear microtubule ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
ribosomal small subunit biogenesis ?
3e-32

BLAST

Cluster Pair #12: 4 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF11_0284 ?
methyltransferase, putative

methyltransferase activity ?
S-adenosylmethionine-dependent methyltransferase activity (IEA) ?
membrane ?
YDL201W ?
protein binding ?
nucleus ?
tRNA (guanine-N7-)-methyltransferase activity ?
tRNA methylation ?
ribosome biogenesis and assembly ?
5.60519e-45

BLAST
PFE1335c ?
hypothetical protein

YGR162W ?
translation initiation factor activity ?
mitochondrion ?
ribosome ?
translational initiation ?
eukaryotic translation initiation factor 4F complex ?
ribosome biogenesis and assembly ?
0.004

BLAST
MAL13P1.344 ?
RNAse L inhibitor protein, putative

nucleotide binding (IEA) ?
iron ion binding (IEA) ?
ATP binding (IEA) ?
electron transport (IEA) ?
electron carrier activity (IEA) ?
ATPase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
YDR091C ?
ribosome-nucleus export ?
iron ion binding ?
nucleus ?
cytoplasm ?
cytosolic ribosome (sensu Eukaryota) ?
translational initiation ?
ATPase activity ?
ribosomal large subunit biogenesis ?
0

BLAST
PFL0310c ?
eukaryotic translation initiation factor 3 subunit 8, putative

translation initiation factor activity ?
eukaryotic translation initiation factor 3 complex ?
translational initiation (IEA) ?
regulation of translational initiation ?
YMR309C ?
translation initiation factor activity ?
cytoplasm ?
eukaryotic translation initiation factor 3 complex ?
translational initiation ?
ribosome biogenesis and assembly ?
9.99995e-41

BLAST

Cluster Pair #13: 4 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
MAL7P1.122 ?
conserved GTP-binding protein, putative

GTP binding ?
signal transduction ?
YBR025C ?
cytoplasm ?
0

BLAST
PFE0545c ?
histamine-releasing factor, putative

cytoplasm (IEA) ?
YKL056C ?
cytoplasm ?
mitochondrion ?
cytosol ?
ribosome ?
protein biosynthesis ?
response to oxidative stress ?
9e-23

BLAST
PF13_0179 ?
isoleucine--tRNA ligase, putative

tRNA ligase activity (IEA) ?
isoleucine-tRNA ligase activity (IEA) ?
ATP binding (IEA) ?
tRNA aminoacylation for protein translation (IEA) ?
isoleucyl-tRNA aminoacylation (IEA) ?
YBL076C ?
isoleucine-tRNA ligase activity ?
cytosol ?
protein biosynthesis ?
0

BLAST
PF11_0447 ?
translation initiation factor eIF-1A, putative

nucleic acid binding (IEA) ?
RNA binding (IEA) ?
translation initiation factor activity ?
translational initiation ?
eukaryotic 43S preinitiation complex ?
YMR260C ?
translation initiation factor activity ?
ribosome ?
translational initiation ?
2.00386e-43

BLAST

Cluster Pair #14: 7 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF14_0656 ?
U2 snRNP auxiliary factor, putative

nuclear mRNA splicing, via spliceosome ?
nucleic acid binding (IEA) ?
RNA binding ?
nucleus (IEA) ?
mRNA processing (IEA) ?
YGL044C ?
RNA binding ?
mRNA cleavage factor complex ?
mRNA polyadenylylation ?
mRNA cleavage ?
protein heterodimerization activity ?
3e-07

BLAST
PFD0835c ?
hypothetical protein

apicoplast ?
YOL027C ?
mitochondrion ?
mitochondrial inner membrane ?
potassium ion transport ?
mitochondrion organization and biogenesis ?
potassium ion homeostasis ?
protein insertion into mitochondrial membrane ?
4e-27

BLAST
PFE0595w ?
hypothetical protein

YLR200W ?
cytoplasm ?
protein folding ?
tubulin folding ?
tubulin binding ?
prefoldin complex ?
0.001

BLAST
PF14_0022 ?
exopolyphosphatase, putative

exopolyphosphatase activity ?
polyphosphate metabolism ?
membrane ?
YHR201C ?
exopolyphosphatase activity ?
cytoplasm ?
mitochondrial matrix ?
cytosol ?
plasma membrane ?
polyphosphate metabolism ?
1e-16

BLAST
PF07_0115 ?
integral membrane protein, putative

metalloendopeptidase activity (IEA) ?
ATP binding (IEA) ?
proteolysis and peptidolysis (IEA) ?
cation transport (IEA) ?
pathogenesis (IEA) ?
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism (IEA) ?
membrane (IEA) ?
integral to membrane ?
apicoplast ?
metal ion binding (IEA) ?
YEL031W ?
mitochondrion ?
endoplasmic reticulum membrane ?
protein amino acid glycosylation ?
calcium ion homeostasis ?
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism ?
5e-29

BLAST
PFA0500w ?
human hepatopoietin-like protein, putative

cell proliferation ?
** also with: YGR029W, clust.pair #14
YPR037C ?
microsome ?
protein thiol-disulfide exchange ?
thiol oxidase activity ?
8e-15

BLAST
PFA0500w ?
human hepatopoietin-like protein, putative

cell proliferation ?
** also with: YPR037C, clust.pair #14
YGR029W ?
mitochondrion ?
mitochondrial intermembrane space ?
iron ion homeostasis ?
response to oxidative stress ?
flavin-linked sulfhydryl oxidase activity ?
thiol oxidase activity ?
mitochondrial intermembrane space protein import ?
4e-14

BLAST

Cluster Pair #15: 6 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF14_0378 ?
triose-phosphate isomerase

triose-phosphate isomerase activity ?
gluconeogenesis ?
glycolysis ?
pentose-phosphate shunt ?
fatty acid biosynthesis ?
metabolism (IEA) ?
YDR050C ?
triose-phosphate isomerase activity ?
cytoplasm ?
glycolysis ?
0

BLAST
PFI1105w ?
Phosphoglycerate kinase

phosphoglycerate kinase activity (IEA) ?
glycolysis (IEA) ?
YCR012W ?
phosphoglycerate kinase activity ?
cytoplasm ?
mitochondrion ?
gluconeogenesis ?
glycolysis ?
0

BLAST
PF14_0598 ?
glyceraldehyde-3-phosphate dehydrogenase

glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity ?
mitochondrion ?
glucose metabolism (IEA) ?
gluconeogenesis ?
glycolysis ?
glyceraldehyde-3-phosphate dehydrogenase activity (IEA) ?
NAD binding (IEA) ?
** also with: YGR192C, clust.pair #15 ** also with: YJR009C, clust.pair #15
YJL052W ?
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity ?
cytoplasm ?
lipid particle ?
gluconeogenesis ?
glycolysis ?
cell wall (sensu Fungi) ?
0

BLAST
PF14_0598 ?
glyceraldehyde-3-phosphate dehydrogenase

glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity ?
mitochondrion ?
glucose metabolism (IEA) ?
gluconeogenesis ?
glycolysis ?
glyceraldehyde-3-phosphate dehydrogenase activity (IEA) ?
NAD binding (IEA) ?
** also with: YJL052W, clust.pair #15 ** also with: YJR009C, clust.pair #15
YGR192C ?
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity ?
cytoplasm ?
mitochondrion ?
lipid particle ?
gluconeogenesis ?
glycolysis ?
cell wall (sensu Fungi) ?
0

BLAST
PF14_0598 ?
glyceraldehyde-3-phosphate dehydrogenase

glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity ?
mitochondrion ?
glucose metabolism (IEA) ?
gluconeogenesis ?
glycolysis ?
glyceraldehyde-3-phosphate dehydrogenase activity (IEA) ?
NAD binding (IEA) ?
** also with: YJL052W, clust.pair #15 ** also with: YGR192C, clust.pair #15
YJR009C ?
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity ?
cytoplasm ?
lipid particle ?
gluconeogenesis ?
glycolysis ?
cell wall (sensu Fungi) ?
0

BLAST
PFL0210c ?
eukaryotic initiation factor 5a, putative

nucleic acid binding (IEA) ?
translation initiation factor activity ?
translational initiation ?
YEL034W ?
translation initiation factor activity ?
protein binding ?
cytoplasm ?
mitochondrion ?
ribosome ?
translational initiation ?
0

BLAST

Cluster Pair #16: 14 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF13_0224 ?
60S ribosomal subunit protein L18, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YMR242C, clust.pair #20
YOR312C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
ribosome biogenesis and assembly ?
4e-34

BLAST
PFD1055w ?
ribosomal protein S19s, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome ?
protein biosynthesis ?
** also with: YOL121C, clust.pair #16
YNL302C ?
ribosomal small subunit-nucleus export ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
rRNA processing ?
protein biosynthesis ?
ribosomal small subunit biogenesis ?
3e-20

BLAST
PFD1055w ?
ribosomal protein S19s, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome ?
protein biosynthesis ?
** also with: YNL302C, clust.pair #16
YOL121C ?
ribosomal small subunit-nucleus export ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
rRNA processing ?
protein biosynthesis ?
ribosomal small subunit biogenesis ?
3e-20

BLAST
PFC0300c ?
60S ribosomal protein L7, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
large ribosomal subunit (IEA) ?
transcription regulator activity (IEA) ?
** also with: YGL076C, clust.pair #19
YPL198W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
1.00053e-42

BLAST
PFE0185c ?
60S ribosomal subunit protein L31, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
** also with: YLR406C, clust.pair #18
YDL075W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
9e-21

BLAST
PF13_0171 ?
60S ribosomal protein L23, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis (IEA) ?
** also with: YER117W, clust.pair #20
YBL087C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PFL2055w ?
40S ribosomal protein S17, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YDR447C ?
ribosomal small subunit assembly and maintenance ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
4e-33

BLAST
PF11_0438 ?
Ribosomal protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
** also with: YPL143W, clust.pair #16
YOR234C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
1e-30

BLAST
PF11_0438 ?
Ribosomal protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
** also with: YOR234C, clust.pair #16
YPL143W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
1e-30

BLAST
PF13_0228 ?
40S ribosomal subunit protein S6, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YPL090C, clust.pair #18
YBR181C ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytoplasm ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF13_0268 ?
ribosomal protein L17, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
large ribosomal subunit (IEA) ?
** also with: YJL177W, clust.pair #19
YKL180W ?
structural constituent of ribosome ?
cytoplasm ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
4.00001e-40

BLAST
PFC0735w ?
40S ribosomal protein S15A, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YJL190C, clust.pair #18
YLR367W ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PFC0775w ?
40S ribosomal protein S11, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YDR025W, clust.pair #16
YBR048W ?
ribosomal small subunit assembly and maintenance ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
regulation of translational fidelity ?
0

BLAST
PFC0775w ?
40S ribosomal protein S11, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YBR048W, clust.pair #16
YDR025W ?
ribosomal small subunit assembly and maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
regulation of translational fidelity ?
0

BLAST

Cluster Pair #17: 9 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF14_0027 ?
ribosomal S27a, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis (IEA) ?
protein modification (IEA) ?
YLR167W ?
ribosomal small subunit assembly and maintenance ?
structural constituent of ribosome ?
cytoplasm ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
protein ubiquitination ?
protein tag ?
ribosome biogenesis and assembly ?
1e-12

BLAST
PF13_0132 ?
60S ribosomal protein L23a, putative

structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
rRNA binding ?
YOL127W ?
ribosomal large subunit assembly and maintenance ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
2e-21

BLAST
PFB0830w ?
Ribosomal protein S26e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YGL189C, clust.pair #17
YER131W ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
2e-26

BLAST
PFB0830w ?
Ribosomal protein S26e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YER131W, clust.pair #17
YGL189C ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
2e-26

BLAST
PF07_0080 ?
40S ribosomal protein S10, putative

structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YOR293W ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
2e-20

BLAST
PF14_0579 ?
ribosomal protein L27, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YDR471W, clust.pair #20
YHR010W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
1e-16

BLAST
MAL13P1.92 ?
40S ribosomal protein S15, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
small ribosomal subunit (IEA) ?
YOL040C ?
ribosomal small subunit-nucleus export ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
5e-36

BLAST
PFC0535w ?
60S ribosomal protein L26, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
large ribosomal subunit (IEA) ?
** also with: YGR034W, clust.pair #19
YLR344W ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
1e-28

BLAST
PFC1020c ?
40S ribosomal protein S3A, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YML063W, clust.pair #19
YLR441C ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST

Cluster Pair #18: 8 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF13_0014 ?
40S ribosomal protein S7 homologue, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YNL096C, clust.pair #20
YOR096W ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
6e-29

BLAST
PFE0810c ?
40S ribosomal subunit protein S14, putative

RNA binding ?
structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YJL191W, clust.pair #20
YCR031C ?
ribosomal small subunit assembly and maintenance ?
telomere maintenance ?
RNA binding ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
processing of 20S pre-rRNA ?
5.60519e-45

BLAST
PFE0185c ?
60S ribosomal subunit protein L31, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
** also with: YDL075W, clust.pair #16
YLR406C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
5e-21

BLAST
PF11_0272 ?
ribosomal protein S18, putative

RNA binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
small ribosomal subunit ?
YDR450W ?
telomere maintenance ?
structural constituent of ribosome ?
mitochondrion ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF08_0076 ?
40S ribosomal protein S16, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YDL083C ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
9.80909e-45

BLAST
PF14_0240 ?
ribosomal protein L21e, putative

structural constituent of ribosome ?
mitochondrion ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YPL079W, clust.pair #19
YBR191W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
4e-28

BLAST
PF13_0228 ?
40S ribosomal subunit protein S6, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YBR181C, clust.pair #16
YPL090C ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PFC0735w ?
40S ribosomal protein S15A, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YLR367W, clust.pair #16
YJL190C ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST

Cluster Pair #19: 9 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF10_0038 ?
ribosomal protein S20e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
small ribosomal subunit (IEA) ?
YHL015W ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
3e-25

BLAST
PF13_0213 ?
60S ribosomal subunit protein L6e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YLR448W ?
ribosomal large subunit assembly and maintenance ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
7e-16

BLAST
PF10_0187 ?
ribosomal protein L30e, putative

structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YGL030W ?
structural constituent of ribosome ?
cytoplasm ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
rRNA processing ?
protein biosynthesis ?
negative regulation of protein biosynthesis ?
negative regulation of nuclear mRNA splicing, via spliceosome ?
2e-26

BLAST
PFC0300c ?
60S ribosomal protein L7, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
large ribosomal subunit (IEA) ?
transcription regulator activity (IEA) ?
** also with: YPL198W, clust.pair #16
YGL076C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
1.00053e-42

BLAST
PF13_0045 ?
40S ribosomal protein S27, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YHR021C, clust.pair #20
YKL156W ?
structural constituent of ribosome ?
cytoplasm ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
5e-27

BLAST
PF14_0240 ?
ribosomal protein L21e, putative

structural constituent of ribosome ?
mitochondrion ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YBR191W, clust.pair #18
YPL079W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
5e-28

BLAST
PFC0535w ?
60S ribosomal protein L26, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
large ribosomal subunit (IEA) ?
** also with: YLR344W, clust.pair #17
YGR034W ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
2e-28

BLAST
PF13_0268 ?
ribosomal protein L17, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
large ribosomal subunit (IEA) ?
** also with: YKL180W, clust.pair #16
YJL177W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
3e-40

BLAST
PFC1020c ?
40S ribosomal protein S3A, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YLR441C, clust.pair #17
YML063W ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST

Cluster Pair #20: 13 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF13_0014 ?
40S ribosomal protein S7 homologue, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YOR096W, clust.pair #18
YNL096C ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
5e-31

BLAST
PF13_0224 ?
60S ribosomal subunit protein L18, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YOR312C, clust.pair #16
YMR242C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
4e-34

BLAST
PFE0810c ?
40S ribosomal subunit protein S14, putative

RNA binding ?
structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YCR031C, clust.pair #18
YJL191W ?
ribosomal small subunit assembly and maintenance ?
RNA binding ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
processing of 20S pre-rRNA ?
5.60519e-45

BLAST
PFI0190w ?
ribosomal protein L32, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis (IEA) ?
YBL092W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
6e-22

BLAST
PFB0455w ?
ribosomal L37ae protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YPR043W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
9e-26

BLAST
PFC0295c ?
40S ribosomal protein S12, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YOR369C ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
9e-19

BLAST
PF13_0045 ?
40S ribosomal protein S27, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YKL156W, clust.pair #19
YHR021C ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
5e-27

BLAST
PF13_0171 ?
60S ribosomal protein L23, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis (IEA) ?
** also with: YBL087C, clust.pair #16
YER117W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
response to drug ?
0

BLAST
PF14_0231 ?
ribosomal protein L7a, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
ribonucleoprotein complex (IEA) ?
ribosome biogenesis and assembly (IEA) ?
** also with: YLL045C, clust.pair #20
YHL033C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
2.00386e-43

BLAST
PF14_0231 ?
ribosomal protein L7a, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
ribonucleoprotein complex (IEA) ?
ribosome biogenesis and assembly (IEA) ?
** also with: YHL033C, clust.pair #20
YLL045C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
2.99878e-43

BLAST
PF14_0579 ?
ribosomal protein L27, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YHR010W, clust.pair #17
YDR471W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
5e-16

BLAST
PF14_0655 ?
RNA helicase-1, putative

RNA cap binding ?
nucleic acid binding (IEA) ?
mRNA binding ?
translation initiation factor activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
regulation of translational initiation ?
ATP-dependent helicase activity ?
eukaryotic translation initiation factor 4F complex ?
** also with: YKR059W, clust.pair #20
YJL138C ?
RNA helicase activity ?
translation initiation factor activity ?
cytoplasm ?
ribosome ?
translational initiation ?
regulation of translational initiation ?
eukaryotic translation initiation factor 4F complex ?
0

BLAST
PF14_0655 ?
RNA helicase-1, putative

RNA cap binding ?
nucleic acid binding (IEA) ?
mRNA binding ?
translation initiation factor activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
regulation of translational initiation ?
ATP-dependent helicase activity ?
eukaryotic translation initiation factor 4F complex ?
** also with: YJL138C, clust.pair #20
YKR059W ?
telomere maintenance ?
translation initiation factor activity ?
ATP-dependent RNA helicase activity ?
ribosome ?
translational initiation ?
eukaryotic translation initiation factor 4F complex ?
0

BLAST

Cluster Pair #21: 24 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PFL1820w ?
hypothetical protein

YLR196W ?
nucleus ?
nucleolus ?
cytoplasm ?
rRNA processing ?
3e-15

BLAST
PFL1470c ?
hypothetical protein

** also with: YCR057C, clust.pair #22
YLR222C ?
small nucleolar ribonucleoprotein complex ?
processing of 20S pre-rRNA ?
snoRNA binding ?
0.012

BLAST
PF14_0185 ?
ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
** also with: YHR065C, clust.pair #22 ** also with: YGL078C, clust.pair #22 ** also with: YJL033W, clust.pair #22 ** also with: YFL002C, clust.pair #23
YMR290C ?
RNA binding ?
ATP-dependent RNA helicase activity ?
nuclear membrane ?
nucleolus ?
rRNA processing ?
RNA-dependent ATPase activity ?
ribosome biogenesis and assembly ?
5e-10

BLAST
PF14_0584 ?
ribosomal protein S4, putative

RNA binding (IEA) ?
structural constituent of ribosome ?
mitochondrial small ribosomal subunit ?
protein biosynthesis ?
YHR148W ?
rRNA modification ?
small nucleolar ribonucleoprotein complex ?
35S primary transcript processing ?
processing of 20S pre-rRNA ?
snoRNA binding ?
ribosome biogenesis and assembly ?
1e-35

BLAST
PF14_0274 ?
hypothetical protein, conserved

YKL191W ?
cytoplasm ?
peptidyl-diphthamide biosynthesis from peptidyl-histidine ?
ribosome biogenesis and assembly ?
8e-14

BLAST
PF13_0177 ?
ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
** also with: YHR065C, clust.pair #22
YHR169W ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
0

BLAST
PF10_0278 ?
hypothetical protein, conserved

YKR081C ?
ribosomal large subunit assembly and maintenance ?
nucleolus ?
5S rRNA binding ?
7S RNA binding ?
rRNA binding ?
processing of 27S pre-rRNA ?
ribosome biogenesis and assembly ?
2e-05

BLAST
PF11_0275 ?
hypothetical protein

YLR409C ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
35S primary transcript processing ?
snoRNA binding ?
ribosome biogenesis and assembly ?
0.083

BLAST
PF11_0274 ?
hypothetical protein

YFR001W ?
mRNA binding ?
nucleus ?
intracellular mRNA localization ?
ribosomal large subunit biogenesis ?
0.002

BLAST
PF07_0083 ?
hypothetical protein, conserved

YNR054C ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
cytoplasm ?
35S primary transcript processing ?
transcription regulator activity ?
ribosome biogenesis and assembly ?
6e-15

BLAST
MAL7P1.24 ?
hypothetical protein, conserved

intracellular (IEA) ?
YER126C ?
nucleus ?
ribosome biogenesis and assembly ?
ribosomal large subunit biogenesis ?
0

BLAST
PF13_0309 ?
hypothetical protein

YLR409C ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
35S primary transcript processing ?
snoRNA binding ?
ribosome biogenesis and assembly ?
1e-17

BLAST
PFI0625c ?
hypothetical protein

translation initiation factor activity (IEA) ?
regulation of translational initiation (IEA) ?
YNL062C ?
tRNA binding ?
nucleus ?
translational initiation ?
tRNA (adenine-N1-)-methyltransferase activity ?
tRNA methylation ?
ribosome biogenesis and assembly ?
5e-07

BLAST
PF07_0121 ?
hypothetical protein, conserved

YHR170W ?
ribosomal large subunit assembly and maintenance ?
ribosomal large subunit-nucleus export ?
RNA binding ?
protein binding ?
cytosol ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
ribosome biogenesis and assembly ?
2.94273e-44

BLAST
PF13_0184 ?
hypothetical protein

metalloendopeptidase activity (IEA) ?
cytoplasm (IEA) ?
proteolysis and peptidolysis (IEA) ?
phosphate transport (IEA) ?
pathogenesis (IEA) ?
membrane ?
metal ion binding (IEA) ?
YDR324C ?
small nucleolar ribonucleoprotein complex ?
processing of 20S pre-rRNA ?
snoRNA binding ?
ribosome biogenesis and assembly ?
2e-07

BLAST
PFL1345c ?
hypothetical protein, conserved

catalytic activity (IEA) ?
iron ion binding (IEA) ?
membrane ?
YPL086C ?
histone acetyltransferase activity ?
nucleus ?
cytoplasm ?
regulation of transcription from RNA polymerase II promoter ?
tRNA modification ?
transcription elongation factor complex ?
0

BLAST
PF14_0635 ?
hypothetical protein, conserved

RNA binding (IEA) ?
YPL211W ?
ribosomal large subunit assembly and maintenance ?
nucleolus ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
rRNA processing ?
ribosome biogenesis and assembly ?
ribosomal large subunit biogenesis ?
2e-35

BLAST
PF10_0200 ?
hypothetical protein, conserved

YNL132W ?
nucleolus ?
ribosome biogenesis and assembly ?
2e-39

BLAST
MAL7P1.113 ?
DEAD box helicase, putative

nucleic acid binding (IEA) ?
RNA binding ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding ?
ATP-dependent helicase activity (IEA) ?
RNA metabolism ?
** also with: YMR290C, clust.pair #21
YKR024C ?
ribosomal large subunit assembly and maintenance ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
5e-26

BLAST
MAL7P1.113 ?
DEAD box helicase, putative

nucleic acid binding (IEA) ?
RNA binding ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding ?
ATP-dependent helicase activity (IEA) ?
RNA metabolism ?
** also with: YKR024C, clust.pair #21
YMR290C ?
RNA binding ?
ATP-dependent RNA helicase activity ?
nuclear membrane ?
nucleolus ?
rRNA processing ?
RNA-dependent ATPase activity ?
ribosome biogenesis and assembly ?
1e-24

BLAST
PF14_0494 ?
hypothetical protein, conserved

mitochondrion ?
YDL060W ?
nucleolus ?
cytoplasm ?
rRNA processing ?
ribosome biogenesis and assembly ?
ribonucleoprotein binding ?
2e-18

BLAST
PF13_0109 ?
N2,N2-dimethylguanosine tRNA methyltransferase, putative

RNA binding (IEA) ?
tRNA (guanine-N2-)-methyltransferase activity ?
tRNA modification ?
tRNA processing (IEA) ?
apicoplast ?
YDR120C ?
tRNA (guanine-N2-)-methyltransferase activity ?
nuclear membrane ?
nuclear inner membrane ?
mitochondrion ?
tRNA methylation ?
ribosome biogenesis and assembly ?
3e-13

BLAST
PF14_0221 ?
hypothetical protein, conserved

GTP binding (IEA) ?
YNR053C ?
ribosomal large subunit-nucleus export ?
GTPase activity ?
nucleus ?
nucleoplasm ?
nucleolus ?
ribosome biogenesis and assembly ?
ribosome assembly ?
0

BLAST
PF08_0065 ?
hypothetical protein, conserved

YMR131C ?
nucleolus ?
ribosome biogenesis and assembly ?
5e-33

BLAST

Cluster Pair #22: 28 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PFD0515w ?
exosome complex exonuclease rrp4, putative

3'-5'-exoribonuclease activity ?
exosome (RNase complex) ?
nucleic acid binding (IEA) ?
RNA binding (IEA) ?
rRNA processing ?
YHR069C ?
3'-5'-exoribonuclease activity ?
nuclear exosome (RNase complex) ?
cytoplasmic exosome (RNase complex) ?
RNA binding ?
35S primary transcript processing ?
mRNA catabolism ?
4e-33

BLAST
PFL2010c ?
DEAD%2FDEAH box helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
RNA metabolism ?
YLR276C ?
ribosomal large subunit assembly and maintenance ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
3e-25

BLAST
PFL1470c ?
hypothetical protein

** also with: YLR222C, clust.pair #21
YCR057C ?
cytokinesis ?
small nucleolar ribonucleoprotein complex ?
cytoplasm ?
35S primary transcript processing ?
establishment of cell polarity (sensu Fungi) ?
processing of 20S pre-rRNA ?
snoRNA binding ?
90S preribosome ?
ribosome biogenesis and assembly ?
0.012

BLAST
PFL1230w ?
hypothetical protein

YLR186W ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
cytoplasm ?
nuclear microtubule ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
ribosomal small subunit biogenesis ?
3e-12

BLAST
PFL2295w ?
hypothetical protein

rRNA processing (IEA) ?
ribonucleoprotein complex (IEA) ?
YKL099C ?
small nucleolar ribonucleoprotein complex ?
processing of 20S pre-rRNA ?
snoRNA binding ?
ribosome biogenesis and assembly ?
0.095

BLAST
MAL13P1.14 ?
ATP-dependent DEAD box helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YMR128W ?
RNA helicase activity ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
mitochondrion ?
processing of 20S pre-rRNA ?
ribosome biogenesis and assembly ?
9.94922e-44

BLAST
PF14_0185 ?
ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
** also with: YMR290C, clust.pair #21 ** also with: YGL078C, clust.pair #22 ** also with: YJL033W, clust.pair #22 ** also with: YFL002C, clust.pair #23
YHR065C ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
1e-09

BLAST
PF14_0185 ?
ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
** also with: YMR290C, clust.pair #21 ** also with: YHR065C, clust.pair #22 ** also with: YJL033W, clust.pair #22 ** also with: YFL002C, clust.pair #23
YGL078C ?
ribosomal large subunit assembly and maintenance ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
2e-08

BLAST
PF14_0185 ?
ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
** also with: YMR290C, clust.pair #21 ** also with: YHR065C, clust.pair #22 ** also with: YGL078C, clust.pair #22 ** also with: YFL002C, clust.pair #23
YJL033W ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
2e-08

BLAST
PFI0860c ?
ATP-dependant RNA helicase, putative

nucleic acid binding (IEA) ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YGL120C ?
U2-type spliceosome disassembly ?
ATP-dependent RNA helicase activity ?
spliceosome complex ?
mitochondrion ?
rRNA processing ?
35S primary transcript processing ?
processing of 27S pre-rRNA ?
processing of 20S pre-rRNA ?
RNA splicing factor activity, transesterification mechanism ?
ribosome biogenesis and assembly ?
ribosomal large subunit biogenesis ?
0

BLAST
PF13_0261 ?
ATP binding protein, putative

ATP binding ?
YOR262W ?
cytoplasm ?
4e-22

BLAST
PF14_0292 ?
hypothetical protein, conserved

GTP binding (IEA) ?
YGL099W ?
ribosome-nucleus export ?
conjugation with cellular fusion ?
GTPase activity ?
cytoplasm ?
sporulation (sensu Fungi) ?
ribosome biogenesis and assembly ?
2e-30

BLAST
PF13_0177 ?
ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
** also with: YHR169W, clust.pair #21
YHR065C ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
0

BLAST
PF14_0456 ?
hypothetical protein, conserved

YLR129W ?
small nucleolar ribonucleoprotein complex ?
processing of 20S pre-rRNA ?
snoRNA binding ?
ribosome biogenesis and assembly ?
5.04467e-44

BLAST
MAL13P1.341 ?
hypothetical protein, conserved

YKL009W ?
telomere maintenance ?
nucleus ?
nucleolus ?
rRNA processing ?
mRNA catabolism ?
ribosome biogenesis and assembly ?
ribosomal large subunit biogenesis ?
4e-06

BLAST
PF14_0157 ?
hypothetical protein

YHR040W ?
nucleic acid binding ?
nucleus ?
cytoplasm ?
snoRNA metabolism ?
0.006

BLAST
PF10_0087 ?
diphthine synthase

diphthine synthase activity ?
metabolism (IEA) ?
methyltransferase activity (IEA) ?
peptidyl-diphthamide biosynthesis from peptidyl-histidine (IEA) ?
YLR172C ?
diphthine synthase activity ?
cytoplasm ?
peptidyl-diphthamide biosynthesis from peptidyl-histidine ?
0

BLAST
PFI0920c ?
hypothetical protein, conserved

tRNA processing (IEA) ?
oxidoreductase activity (IEA) ?
apicoplast ?
FAD binding (IEA) ?
YML080W ?
nucleus ?
tRNA modification ?
tRNA dihydrouridine synthase activity ?
9e-10

BLAST
PFB0860c ?
RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YHR065C ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
0

BLAST
PFE1310c ?
hypothetical protein

** also with: YCR057C, clust.pair #22 ** also with: YPR169W, clust.pair #23
YLR129W ?
small nucleolar ribonucleoprotein complex ?
processing of 20S pre-rRNA ?
snoRNA binding ?
ribosome biogenesis and assembly ?
0.0006

BLAST
PFE1310c ?
hypothetical protein

** also with: YLR129W, clust.pair #22 ** also with: YPR169W, clust.pair #23
YCR057C ?
cytokinesis ?
small nucleolar ribonucleoprotein complex ?
cytoplasm ?
35S primary transcript processing ?
establishment of cell polarity (sensu Fungi) ?
processing of 20S pre-rRNA ?
snoRNA binding ?
90S preribosome ?
ribosome biogenesis and assembly ?
0.001

BLAST
PF11_0471 ?
hypothetical protein

YCR072C ?
ribosomal large subunit assembly and maintenance ?
nucleolus ?
ribosome ?
ribosome biogenesis and assembly ?
2.8026e-45

BLAST
PF14_0068 ?
fibrillarin, putative

RNA binding (IEA) ?
nucleus (IEA) ?
small nucleolar ribonucleoprotein complex ?
mitochondrion ?
rRNA processing ?
YDL014W ?
ribosomal large subunit assembly and maintenance ?
rRNA modification ?
RNA methylation ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
ribosome ?
35S primary transcript processing ?
methyltransferase activity ?
processing of 20S pre-rRNA ?
snoRNA 3'-end processing ?
ribosome biogenesis and assembly ?
0

BLAST
PF08_0130 ?
wd repeat protein, putative

YCR057C ?
cytokinesis ?
small nucleolar ribonucleoprotein complex ?
cytoplasm ?
35S primary transcript processing ?
establishment of cell polarity (sensu Fungi) ?
processing of 20S pre-rRNA ?
snoRNA binding ?
90S preribosome ?
ribosome biogenesis and assembly ?
0

BLAST
PFE1115c ?
s-adenosylmethionine-dependent methyltransferase, putative

S-adenosylmethionine-dependent methyltransferase activity ?
YCR047C ?
bud site selection ?
nucleus ?
cytoplasm ?
S-adenosylmethionine-dependent methyltransferase activity ?
0

BLAST
PF07_0067 ?
hypothetical protein

YGR245C ?
nucleus ?
traversing start control point of mitotic cell cycle ?
actin cytoskeleton organization and biogenesis ?
ribosome biogenesis and assembly ?
ribosome assembly ?
1e-09

BLAST
PF14_0156 ?
dimethyladenosine transferase, putative

rRNA modification ?
rRNA (adenine-N6,N6-)-dimethyltransferase activity (IEA) ?
mitochondrion ?
rRNA processing (IEA) ?
rRNA methyltransferase activity ?
S-adenosylmethionine-dependent methyltransferase activity (IEA) ?
rRNA (adenine) methyltransferase activity (IEA) ?
YPL266W ?
rRNA modification ?
rRNA (adenine-N6,N6-)-dimethyltransferase activity ?
nucleolus ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
0

BLAST
PF13_0219 ?
hypothetical protein

YOR206W ?
ribosome-nucleus export ?
nucleus ?
mitochondrion ?
Noc1p-Noc2p complex ?
Noc2p-Noc3p complex ?
ribosome biogenesis and assembly ?
ribosome assembly ?
0.074

BLAST

Cluster Pair #23: 18 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF14_0661 ?
hypothetical protein, conserved

nucleic acid binding (IEA) ?
YOR145C ?
nucleus ?
nucleolus ?
rRNA processing ?
35S primary transcript processing ?
protein complex assembly ?
ribosome biogenesis and assembly ?
unfolded protein binding ?
0

BLAST
PF07_0122 ?
hypothetical protein, conserved

YOL077C ?
ribosomal large subunit assembly and maintenance ?
nucleolus ?
5S rRNA binding ?
rRNA primary transcript binding ?
ribosome biogenesis and assembly ?
1e-35

BLAST
PF14_0150 ?
RNA polymerase small subunit, putative

DNA binding (IEA) ?
DNA-directed RNA polymerase activity ?
transcription ?
protein dimerization activity (IEA) ?
YNL113W ?
DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase III complex ?
DNA-directed RNA polymerase I complex ?
transcription from RNA polymerase I promoter ?
transcription from RNA polymerase III promoter ?
ribosome biogenesis and assembly ?
1e-18

BLAST
PF10_0194 ?
hypothetical protein

nucleic acid binding (IEA) ?
YOL041C ?
RNA binding ?
nucleolus ?
rRNA metabolism ?
1e-13

BLAST
PF14_0185 ?
ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
** also with: YMR290C, clust.pair #21 ** also with: YHR065C, clust.pair #22 ** also with: YGL078C, clust.pair #22 ** also with: YJL033W, clust.pair #22
YFL002C ?
ribosomal large subunit assembly and maintenance ?
ATP-dependent RNA helicase activity ?
nucleolus ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
6e-10

BLAST
PF13_0286 ?
methyltransferase, putative

rRNA processing ?
RNA methyltransferase activity ?
YCL054W ?
nucleus ?
nucleolus ?
rRNA (uridine-2'-O-)-methyltransferase activity ?
rRNA (guanine) methyltransferase activity ?
processing of 27S pre-rRNA ?
rRNA methylation ?
0

BLAST
PF07_0027 ?
DNA-directed RNA polymerase 2 8.2 kDa polypeptide, putative

DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase II, core complex ?
transcription (IEA) ?
transcription from RNA polymerase II promoter ?
YOR210W ?
DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase II, core complex ?
DNA-directed RNA polymerase III complex ?
DNA-directed RNA polymerase I complex ?
transcription from RNA polymerase I promoter ?
transcription from RNA polymerase II promoter ?
transcription from RNA polymerase III promoter ?
2e-17

BLAST
PFB0175c ?
hypothetical protein

YAL025C ?
nucleolus ?
processing of 27S pre-rRNA ?
ribosome biogenesis and assembly ?
ribosomal large subunit biogenesis ?
1e-25

BLAST
PF10_0277 ?
hypothetical protein, conserved

YKL172W ?
nuclear division ?
nucleolus ?
rRNA processing ?
ribosome biogenesis and assembly ?
2e-07

BLAST
PFB0290c ?
transcription factor, putative

DNA binding (IEA) ?
transcription factor activity ?
DNA-directed RNA polymerase III complex ?
RNA elongation (IEA) ?
regulation of transcription, DNA-dependent (IEA) ?
transcription from RNA polymerase III promoter ?
YDR045C ?
DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase III complex ?
transcription from RNA polymerase III promoter ?
7e-15

BLAST
PFB0370c ?
RNA-binding protein, putative

YCL059C ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
rRNA processing ?
35S primary transcript processing ?
ribosome biogenesis and assembly ?
0

BLAST
PF13_0035 ?
hypothetical protein

YDR449C ?
small nucleolar ribonucleoprotein complex ?
processing of 20S pre-rRNA ?
snoRNA binding ?
ribosome biogenesis and assembly ?
4e-07

BLAST
PFE0515w ?
hypothetical protein

YOL022C ?
cytoplasm ?
0.005

BLAST
PFE1310c ?
hypothetical protein

** also with: YLR129W, clust.pair #22 ** also with: YCR057C, clust.pair #22
YPR169W ?
nucleus ?
nucleolus ?
protein monoubiquitination ?
0.0001

BLAST
PFI1070c ?
hypothetical protein

YHR088W ?
ribosomal large subunit assembly and maintenance ?
nucleolus ?
processing of 27S pre-rRNA ?
rRNA primary transcript binding ?
ribosome biogenesis and assembly ?
5e-18

BLAST
PFE1435c ?
hypothetical protein

YER006W ?
GTPase activity ?
nucleus ?
nucleolus ?
rRNA processing ?
ribosome biogenesis and assembly ?
4e-09

BLAST
PF11_0191 ?
hypothetical protein

YLR197W ?
rRNA modification ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
35S primary transcript processing ?
processing of 20S pre-rRNA ?
box C/D snoRNP complex ?
ribosome biogenesis and assembly ?
0

BLAST
PF14_0174 ?
hypothetical protein, conserved

RNA binding (IEA) ?
pseudouridylate synthase activity (IEA) ?
RNA processing (IEA) ?
YLR175W ?
pseudouridylate synthase activity ?
nucleolus ?
35S primary transcript processing ?
rRNA pseudouridine synthesis ?
box H/ACA snoRNP complex ?
ribosome biogenesis and assembly ?
0

BLAST

Cluster Pair #24: 4 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PFD0455w ?
ribosomal processing protein, putative

rRNA modification ?
small nucleolar ribonucleoprotein complex ?
YLL011W ?
rRNA modification ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
35S primary transcript processing ?
processing of 20S pre-rRNA ?
snoRNA binding ?
small nuclear ribonucleoprotein complex ?
0

BLAST
PFL0830w ?
hypothetical protein

nucleic acid binding (IEA) ?
YPR112C ?
nucleolus ?
35S primary transcript processing ?
snoRNA binding ?
rRNA primary transcript binding ?
1.4013e-45

BLAST
PF10_0266 ?
hypothetical protein

YJR002W ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
35S primary transcript processing ?
processing of 20S pre-rRNA ?
ribosome biogenesis and assembly ?
2e-10

BLAST
PFD0975w ?
ROI kinase-like protein

YNL207W ?
protein kinase activity ?
nucleocytoplasmic transporter activity ?
nucleus ?
cytoplasm ?
cytosol ?
processing of 20S pre-rRNA ?
0

BLAST

Cluster Pair #25: 9 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PFI0685w ?
pseudouridylate synthase, putative

RNA binding (IEA) ?
RNA processing (IEA) ?
pseudouridine synthase activity (IEA) ?
apicoplast ?
YOL066C ?
pseudouridylate synthase activity ?
cytoplasm ?
riboflavin biosynthesis ?
tRNA-pseudouridine synthase activity ?
DRAP deaminase activity ?
tRNA pseudouridine synthesis ?
2e-23

BLAST
PF13_0042 ?
fork head domain protein, putative

protein binding ?
nucleus ?
YLR016C ?
nuclear mRNA splicing, via spliceosome ?
nucleus ?
cytoplasm ?
mRNA-nucleus export ?
1e-13

BLAST
PFB0635w ?
T-complex protein 1, putative

protein binding (IEA) ?
ATP binding (IEA) ?
protein folding ?
ATPase activity, coupled ?
cellular protein metabolism (IEA) ?
unfolded protein binding (IEA) ?
YJL008C ?
cytoplasm ?
chaperonin-containing T-complex ?
cytoskeleton ?
protein folding ?
cytoskeleton organization and biogenesis ?
unfolded protein binding ?
0

BLAST
PFE1040c ?
hypothetical protein

YLR418C ?
telomere maintenance ?
nucleus ?
DNA recombination ?
RNA elongation from RNA polymerase II promoter ?
transcription elongation factor complex ?
histone methylation ?
Cdc73/Paf1 complex ?
RNA polymerase II transcription elongation factor activity ?
4e-06

BLAST
PFC0270w ?
hypothetical protein

YNL281W ?
telomere maintenance ?
ATPase stimulator activity ?
nucleus ?
cytoplasm ?
protein folding ?
response to stress ?
chaperone activator activity ?
chaperone binding ?
2e-06

BLAST
PF11_0258 ?
co-chaperone GrpE, putative

adenyl-nucleotide exchange factor activity (IEA) ?
protein binding (IEA) ?
mitochondrion ?
mitochondrial matrix ?
protein folding (IEA) ?
mitochondrial matrix protein import ?
protein homodimerization activity (IEA) ?
unfolded protein binding ?
chaperone binding (IEA) ?
YOR232W ?
presequence translocase-associated import motor ?
mitochondrion ?
mitochondrial matrix ?
mitochondrial matrix protein import ?
unfolded protein binding ?
1e-26

BLAST
PF14_0599 ?
hypothetical protein

YPR173C ?
cytoplasm ?
endoplasmic reticulum ?
sterol metabolism ?
ATPase activity ?
protein retention in Golgi ?
late endosome to vacuole transport ?
0.007

BLAST
PF13_0143 ?
phosphoribosylpyrophosphate synthetase

ribose phosphate diphosphokinase activity ?
pentose-phosphate shunt ?
purine ribonucleoside salvage ?
nucleoside metabolism (IEA) ?
nucleotide biosynthesis (IEA) ?
YER099C ?
histidine biosynthesis ?
tryptophan biosynthesis ?
ribose phosphate diphosphokinase activity ?
cytoplasm ?
purine ribonucleoside salvage ?
'de novo' IMP biosynthesis ?
'de novo' pyrimidine base biosynthesis ?
0

BLAST
PFA0145c ?
aspartyl-tRNA synthetase

nucleic acid binding (IEA) ?
tRNA ligase activity (IEA) ?
aspartate-tRNA ligase activity ?
ATP binding (IEA) ?
cytoplasm (IEA) ?
tRNA aminoacylation for protein translation (IEA) ?
aspartyl-tRNA aminoacylation ?
YLL018C ?
RNA binding ?
aspartate-tRNA ligase activity ?
cytoplasm ?
protein biosynthesis ?
0

BLAST

Cluster Pair #26: 3 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
MAL7P1.147 ?
ubiquitin carboxyl-terminal hydrolase, putative

cysteine-type endopeptidase activity (IEA) ?
ubiquitin thiolesterase activity ?
ubiquitin-dependent protein catabolism (IEA) ?
protein deubiquitination ?
YMR304W ?
ubiquitin-specific protease activity ?
cytoplasm ?
protein deubiquitination ?
0

BLAST
PF14_0276 ?
ribosomal protein L15, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
mitochondrial large ribosomal subunit ?
ribosome (IEA) ?
protein biosynthesis ?
YNL284C ?
structural constituent of ribosome ?
mitochondrion ?
mitochondrial large ribosomal subunit ?
protein biosynthesis ?
5e-10

BLAST
PF11_0408 ?
hypothetical protein

YNL306W ?
structural constituent of ribosome ?
mitochondrion ?
mitochondrial small ribosomal subunit ?
protein biosynthesis ?
0.047

BLAST

Cluster Pair #27: 7 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF07_0023 ?
DNA replication licensing factor mcm7 homologue, putative

nucleotide binding (IEA) ?
nucleic acid binding (IEA) ?
DNA binding (IEA) ?
ATP binding (IEA) ?
nucleus (IEA) ?
DNA replication initiation ?
DNA-dependent ATPase activity ?
photosynthesis (IEA) ?
chlorophyll biosynthesis (IEA) ?
magnesium chelatase activity (IEA) ?
ATPase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
YBR202W ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
ATP binding ?
nucleus ?
pre-replicative complex ?
cytoplasm ?
pre-replicative complex formation and maintenance ?
DNA unwinding ?
DNA replication initiation ?
MCM complex ?
0

BLAST
PF13_0291 ?
replication licensing factor, putative

nucleic acid binding (IEA) ?
DNA binding ?
ATP binding (IEA) ?
nucleus (IEA) ?
DNA replication initiation ?
DNA-dependent ATPase activity ?
ATPase activity (IEA) ?
YGL201C ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
nucleus ?
pre-replicative complex ?
cytoplasm ?
DNA unwinding ?
DNA replication initiation ?
MCM complex ?
0

BLAST
PFE1345c ?
minichromosome maintenance protein 3, putative

nucleotide binding (IEA) ?
nucleic acid binding (IEA) ?
DNA binding (IEA) ?
ATP binding (IEA) ?
nucleus (IEA) ?
DNA replication initiation (IEA) ?
DNA-dependent ATPase activity (IEA) ?
photosynthesis (IEA) ?
chlorophyll biosynthesis (IEA) ?
magnesium chelatase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
YEL032W ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
nucleus ?
pre-replicative complex ?
cytoplasm ?
pre-replicative complex formation and maintenance ?
DNA unwinding ?
DNA replication initiation ?
MCM complex ?
0

BLAST
PFL0560c ?
minichromosome maintenance protein, putative

nucleic acid binding (IEA) ?
DNA binding (IEA) ?
ATP-dependent DNA helicase activity ?
ATP binding ?
pre-replicative complex ?
DNA replication initiation ?
DNA strand elongation ?
DNA-dependent ATPase activity ?
** also with: YLR274W, clust.pair #27
YBL023C ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
nucleus ?
pre-replicative complex ?
cytoplasm ?
pre-replicative complex formation and maintenance ?
DNA unwinding ?
DNA replication initiation ?
MCM complex ?
2e-37

BLAST
PFL0560c ?
minichromosome maintenance protein, putative

nucleic acid binding (IEA) ?
DNA binding (IEA) ?
ATP-dependent DNA helicase activity ?
ATP binding ?
pre-replicative complex ?
DNA replication initiation ?
DNA strand elongation ?
DNA-dependent ATPase activity ?
** also with: YBL023C, clust.pair #27
YLR274W ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
pre-replicative complex ?
replication fork ?
cytoplasm ?
pre-replicative complex formation and maintenance ?
DNA unwinding ?
DNA replication initiation ?
establishment of chromatin silencing ?
MCM complex ?
1e-33

BLAST
PFL1370w ?
NIMA-related protein kinase %28Pfnek-1%29

protein kinase activity (IEA) ?
protein serine/threonine kinase activity ?
protein-tyrosine kinase activity (IEA) ?
ATP binding (IEA) ?
protein amino acid phosphorylation ?
mitosis ?
YAR018C ?
protein kinase activity ?
chromosome segregation ?
1e-38

BLAST
PFL0580w ?
DNA replication licensing factor mcm5, putative

nucleic acid binding (IEA) ?
DNA binding (IEA) ?
ATP-dependent DNA helicase activity ?
ATP binding ?
nucleus (IEA) ?
pre-replicative complex ?
DNA replication initiation ?
DNA strand elongation ?
DNA-dependent ATPase activity ?
YLR274W ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
pre-replicative complex ?
replication fork ?
cytoplasm ?
pre-replicative complex formation and maintenance ?
DNA unwinding ?
DNA replication initiation ?
establishment of chromatin silencing ?
MCM complex ?
0

BLAST

Cluster Pair #28: 9 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF11_0488 ?
hypothetical protein

protein kinase activity (IEA) ?
protein serine/threonine kinase activity (IEA) ?
protein-tyrosine kinase activity (IEA) ?
ATP binding (IEA) ?
protein amino acid phosphorylation (IEA) ?
YPL153C ?
DNA replication origin binding ?
protein threonine/tyrosine kinase activity ?
nucleus ?
nucleobase, nucleoside, nucleotide and nucleic acid metabolism ?
DNA replication initiation ?
DNA repair ?
deoxyribonucleoside triphosphate biosynthesis ?
2e-14

BLAST
PFI0530c ?
DNA primase, large subunit, putative

DNA primase activity (IEA) ?
alpha DNA polymerase:primase complex (IEA) ?
DNA replication, synthesis of RNA primer (IEA) ?
YKL045W ?
DNA synthesis during DNA repair ?
DNA primase activity ?
nucleus ?
nuclear membrane ?
alpha DNA polymerase:primase complex ?
DNA replication ?
DNA replication, synthesis of RNA primer ?
DNA replication initiation ?
lagging strand elongation ?
9.80909e-45

BLAST
PF14_0254 ?
DNA mismatch repair protein Msh2p, putative

damaged DNA binding ?
ATP binding (IEA) ?
DNA metabolism (IEA) ?
mismatch repair ?
YOL090W ?
nuclear chromosome ?
meiotic mismatch repair ?
removal of nonhomologous ends ?
ATP binding ?
nucleus ?
mismatch repair ?
DNA recombination ?
meiotic gene conversion ?
mitotic recombination ?
ATPase activity ?
chromatin silencing at silent mating-type cassette ?
0

BLAST
PFD0470c ?
replication factor a protein, putative

nucleic acid binding (IEA) ?
DNA replication factor A complex ?
DNA replication ?
DNA-dependent DNA replication ?
YAR007C ?
double-strand break repair via homologous recombination ?
chromosome, telomeric region ?
damaged DNA binding ?
single-stranded DNA binding ?
nucleus ?
DNA replication factor A complex ?
cytoplasm ?
DNA unwinding ?
DNA replication, synthesis of RNA primer ?
DNA strand elongation ?
nucleotide-excision repair ?
postreplication repair ?
DNA recombination ?
9.94922e-44

BLAST
PFI0235w ?
replication factor A-related protein, putative

nucleic acid binding (IEA) ?
YAR007C ?
double-strand break repair via homologous recombination ?
chromosome, telomeric region ?
damaged DNA binding ?
single-stranded DNA binding ?
nucleus ?
DNA replication factor A complex ?
cytoplasm ?
DNA unwinding ?
DNA replication, synthesis of RNA primer ?
DNA strand elongation ?
nucleotide-excision repair ?
postreplication repair ?
DNA recombination ?
1e-28

BLAST
PF07_0012 ?
hypothetical protein

YAR003W ?
telomere maintenance ?
chromatin silencing at telomere ?
regulation of transcription, DNA-dependent ?
histone methylation ?
histone lysine N-methyltransferase activity (H3-K4 specific) ?
COMPASS complex ?
8e-06

BLAST
MAL13P1.326 ?
ferrochelatase, putative

ferrochelatase activity ?
heme biosynthesis ?
ferrous iron binding ?
YOR176W ?
ferrochelatase activity ?
mitochondrion ?
mitochondrial inner membrane ?
heme biosynthesis ?
8e-13

BLAST
PF13_0328 ?
proliferating cell nuclear antigen

DNA binding (IEA) ?
nucleus (IEA) ?
DNA replication factor C complex (IEA) ?
regulation of DNA replication (IEA) ?
DNA polymerase processivity factor activity (IEA) ?
YBR088C ?
nucleus ?
replication fork ?
leading strand elongation ?
lagging strand elongation ?
mutagenesis ?
base-excision repair ?
nucleotide-excision repair ?
mismatch repair ?
postreplication repair ?
chromatin silencing at telomere ?
DNA polymerase processivity factor activity ?
chromatin silencing at silent mating-type cassette ?
2e-37

BLAST
PFE0270c ?
DNA repair protein, putative

damaged DNA binding ?
ATP binding (IEA) ?
DNA metabolism (IEA) ?
DNA repair ?
mismatch repair (IEA) ?
YDR097C ?
meiotic mismatch repair ?
ATP binding ?
nucleus ?
mismatch repair ?
ATPase activity ?
0

BLAST

Cluster Pair #29: 7 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF13_0316 ?
40S ribosomal protein S13

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YDR064W ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF14_0296 ?
ribosomal protein L14, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
apicoplast ?
** also with: YKL006W, clust.pair #33
YHL001W ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0.006

BLAST
PFC0200w ?
60S Ribosomal protein L44, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YHR141C, clust.pair #33
YNL162W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
6e-30

BLAST
PFC0290w ?
40S ribosomal protein S23, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
small ribosomal subunit (IEA) ?
** also with: YGR118W, clust.pair #32
YPR132W ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
regulation of translational fidelity ?
0

BLAST
PF11_0260 ?
ribosomal protein L35, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
** also with: YDL136W, clust.pair #31
YDL191W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
3e-08

BLAST
MAL13P1.209 ?
60S ribosomal subunit porotein L18, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YNL301C, clust.pair #33
YOL120C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
8.00001e-42

BLAST
PF11_0065 ?
ribosomal protein S4, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
protein biosynthesis ?
small ribosomal subunit ?
** also with: YHR203C, clust.pair #32
YJR145C ?
telomere maintenance ?
structural constituent of ribosome ?
cytoplasm ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
processing of 20S pre-rRNA ?
0

BLAST

Cluster Pair #30: 7 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF14_0083 ?
ribosomal protein S8e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YBL072C, clust.pair #31
YER102W ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF07_0043 ?
60S ribosomal protein L34-a, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis (IEA) ?
** also with: YIL052C, clust.pair #32
YER056C-A ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
1e-30

BLAST
PFD0770c ?
ribosomal protein l15, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome ?
protein biosynthesis ?
** also with: YMR121C, clust.pair #33
YLR029C ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF08_0039 ?
ribosomal protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YLR061W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
1e-07

BLAST
PFB0885w ?
40S ribosomal protein S30, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YOR182C ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
4e-13

BLAST
PF13_0049 ?
60S ribosomal protein L24, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YGL031C, clust.pair #30
YGR148C ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
3e-10

BLAST
PF13_0049 ?
60S ribosomal protein L24, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YGR148C, clust.pair #30
YGL031C ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
4e-10

BLAST

Cluster Pair #31: 15 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF11_0043 ?
60S acidic ribosomal protein p1, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
translational elongation (IEA) ?
large ribosomal subunit ?
** also with: YDL130W, clust.pair #31
YDL081C ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
translational elongation ?
2e-06

BLAST
PF11_0043 ?
60S acidic ribosomal protein p1, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
translational elongation (IEA) ?
large ribosomal subunit ?
** also with: YDL081C, clust.pair #31
YDL130W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
translational elongation ?
2e-05

BLAST
PF08_0019 ?
guanine nucleotide-binding protein, putative

protein kinase C binding ?
heterotrimeric G-protein complex ?
G-protein coupled receptor protein signaling pathway ?
YMR116C ?
telomere maintenance ?
cytoplasm ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
negative regulation of protein biosynthesis ?
0

BLAST
PF14_0083 ?
ribosomal protein S8e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YER102W, clust.pair #30
YBL072C ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF14_0391 ?
ribosomal protein L1, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YPL220W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF10_0264 ?
40S ribosomal protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
small ribosomal subunit (IEA) ?
** also with: YGR214W, clust.pair #33
YLR048W ?
ribosomal small subunit assembly and maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PFE1005w ?
40S ribosomal subunit protein S9, putative

RNA binding (IEA) ?
structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis (IEA) ?
small ribosomal subunit (IEA) ?
** also with: YPL081W, clust.pair #32
YBR189W ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
regulation of translational fidelity ?
0

BLAST
PF11_0260 ?
ribosomal protein L35, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
** also with: YDL191W, clust.pair #29
YDL136W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
3e-08

BLAST
PF11_0313 ?
ribosomal phosphoprotein P0

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
translational elongation (IEA) ?
ribosome biogenesis and assembly (IEA) ?
YLR340W ?
ribosomal large subunit assembly and maintenance ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
translational elongation ?
0

BLAST
PF14_0585 ?
ribosomal protein S28e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YLR264W, clust.pair #33
YOR167C ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
5e-12

BLAST
PF13_0304 ?
elongation factor 1 alpha

translation elongation factor activity ?
GTP binding (IEA) ?
cytoplasm (IEA) ?
eukaryotic translation elongation factor 1 complex ?
protein biosynthesis (IEA) ?
translational elongation ?
** also with: YPR080W, clust.pair #32
YBR118W ?
translation elongation factor activity ?
ribosome ?
eukaryotic translation elongation factor 1 complex ?
tRNA-nucleus export ?
translational elongation ?
0

BLAST
PFC0870w ?
elongation factor 1 %28EF-1%29, putative

translation elongation factor activity ?
eukaryotic translation elongation factor 1 complex ?
translational elongation ?
YAL003W ?
translation elongation factor activity ?
ribosome ?
eukaryotic translation elongation factor 1 complex ?
translational elongation ?
3e-15

BLAST
PFC0400w ?
60S Acidic ribosomal protein P2

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
translational elongation ?
large ribosomal subunit ?
** also with: YOL039W, clust.pair #33
YDR382W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
translational elongation ?
9e-11

BLAST
PFE0350c ?
60S ribosomal subunit protein L4%2FL1, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
** also with: YDR012W, clust.pair #31
YBR031W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PFE0350c ?
60S ribosomal subunit protein L4%2FL1, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
** also with: YBR031W, clust.pair #31
YDR012W ?
structural constituent of ribosome ?
cytoplasm ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST

Cluster Pair #32: 14 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF14_0448 ?
ribosomal protein S2, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
small ribosomal subunit (IEA) ?
YGL123W ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
regulation of translational fidelity ?
0

BLAST
PF13_0214 ?
elongation factor 1-gamma, putative

translation elongation factor activity ?
glutathione transferase activity ?
eukaryotic translation elongation factor 1 complex ?
translational elongation ?
YKL081W ?
translation elongation factor activity ?
mitochondrion ?
ribosome ?
eukaryotic translation elongation factor 1 complex ?
translational elongation ?
4e-24

BLAST
PF07_0043 ?
60S ribosomal protein L34-a, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis (IEA) ?
** also with: YER056C-A, clust.pair #30
YIL052C ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
1e-30

BLAST
PF10_0103 ?
eukaryotic translation initiation factor 2, beta, putative

RNA binding ?
translation initiation factor activity ?
eukaryotic translation initiation factor 2 complex ?
translational initiation ?
YPL237W ?
translation initiation factor activity ?
ribosome ?
eukaryotic translation initiation factor 2 complex ?
translational initiation ?
6e-32

BLAST
PF10_0043 ?
ribosomal protein L13, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
large ribosomal subunit (IEA) ?
** also with: YNL069C, clust.pair #33
YIL133C ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PFC0290w ?
40S ribosomal protein S23, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
small ribosomal subunit (IEA) ?
** also with: YPR132W, clust.pair #29
YGR118W ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
regulation of translational fidelity ?
0

BLAST
PFE1005w ?
40S ribosomal subunit protein S9, putative

RNA binding (IEA) ?
structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis (IEA) ?
small ribosomal subunit (IEA) ?
** also with: YBR189W, clust.pair #31
YPL081W ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytoplasm ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
regulation of translational fidelity ?
0

BLAST
PF14_0141 ?
ribosomal protein L10, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YLR075W ?
ribosomal large subunit assembly and maintenance ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF13_0304 ?
elongation factor 1 alpha

translation elongation factor activity ?
GTP binding (IEA) ?
cytoplasm (IEA) ?
eukaryotic translation elongation factor 1 complex ?
protein biosynthesis (IEA) ?
translational elongation ?
** also with: YBR118W, clust.pair #31
YPR080W ?
translation elongation factor activity ?
ribosome ?
eukaryotic translation elongation factor 1 complex ?
tRNA-nucleus export ?
translational elongation ?
0

BLAST
PF13_0129 ?
ribosomal protein L6 homologue, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
** also with: YNL067W, clust.pair #32
YGL147C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
9.99995e-41

BLAST
PF13_0129 ?
ribosomal protein L6 homologue, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis ?
large ribosomal subunit ?
** also with: YGL147C, clust.pair #32
YNL067W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
9.99995e-41

BLAST
PF11_0065 ?
ribosomal protein S4, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
protein biosynthesis ?
small ribosomal subunit ?
** also with: YJR145C, clust.pair #29
YHR203C ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF07_0079 ?
60S ribosomal protein L11a, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YPR102C, clust.pair #32
YGR085C ?
ribosomal large subunit assembly and maintenance ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF07_0079 ?
60S ribosomal protein L11a, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YGR085C, clust.pair #32
YPR102C ?
ribosomal large subunit assembly and maintenance ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST

Cluster Pair #33: 22 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF14_0125 ?
deoxyhypusine synthase

protein biosynthesis ?
hypusine biosynthesis from peptidyl-lysine ?
membrane ?
spermidine catabolism to deoxyhypusine, using deoxyhypusine synthase ?
YHR068W ?
cytoplasm ?
hypusine biosynthesis from peptidyl-lysine ?
transferase activity, transferring alkyl or aryl (other than methyl) groups ?
9.80909e-45

BLAST
PFD1070w ?
eukaryotic initiation factor, putative

nucleic acid binding (IEA) ?
translation initiation factor activity ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
regulation of translational initiation ?
ATP-dependent helicase activity (IEA) ?
eukaryotic translation initiation factor 4F complex ?
** also with: YKR059W, clust.pair #33
YJL138C ?
RNA helicase activity ?
translation initiation factor activity ?
cytoplasm ?
ribosome ?
translational initiation ?
regulation of translational initiation ?
eukaryotic translation initiation factor 4F complex ?
0

BLAST
PFD1070w ?
eukaryotic initiation factor, putative

nucleic acid binding (IEA) ?
translation initiation factor activity ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
regulation of translational initiation ?
ATP-dependent helicase activity (IEA) ?
eukaryotic translation initiation factor 4F complex ?
** also with: YJL138C, clust.pair #33
YKR059W ?
telomere maintenance ?
translation initiation factor activity ?
ATP-dependent RNA helicase activity ?
ribosome ?
translational initiation ?
eukaryotic translation initiation factor 4F complex ?
0

BLAST
PFD0770c ?
ribosomal protein l15, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome ?
protein biosynthesis ?
** also with: YLR029C, clust.pair #30
YMR121C ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF14_0296 ?
ribosomal protein L14, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
apicoplast ?
** also with: YHL001W, clust.pair #29
YKL006W ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0.004

BLAST
MAL8P1.40 ?
RNA-binding protein, putative

nucleic acid binding (IEA) ?
RNA binding ?
regulation of protein biosynthesis ?
regulation of translation ?
YER165W ?
nucleus ?
cytoplasm ?
ribosome ?
regulation of translational initiation ?
poly(A) binding ?
4e-13

BLAST
PF08_0075 ?
60S ribosomal protein L13, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YDL082W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
3e-18

BLAST
PFC0200w ?
60S Ribosomal protein L44, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YNL162W, clust.pair #29
YHR141C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
6e-30

BLAST
PF10_0264 ?
40S ribosomal protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
small ribosomal subunit (IEA) ?
** also with: YLR048W, clust.pair #31
YGR214W ?
ribosomal small subunit assembly and maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF10_0043 ?
ribosomal protein L13, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
large ribosomal subunit (IEA) ?
** also with: YIL133C, clust.pair #32
YNL069C ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF10_0272 ?
ribosomal protein L3, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
YOR063W ?
ribosomal large subunit assembly and maintenance ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PFE0975c ?
40S ribosomal subunit protein S24, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis (IEA) ?
** also with: YIL069C, clust.pair #33
YER074W ?
structural constituent of ribosome ?
mitochondrion ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
3e-33

BLAST
PFE0975c ?
40S ribosomal subunit protein S24, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis (IEA) ?
** also with: YER074W, clust.pair #33
YIL069C ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
3e-33

BLAST
PF14_0230 ?
Ribosomal protein family L5, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
5S rRNA binding (IEA) ?
YPL131W ?
ribosomal large subunit assembly and maintenance ?
RNA binding ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PF14_0627 ?
ribosomal protein S3, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
small ribosomal subunit (IEA) ?
YNL178W ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
response to DNA damage stimulus ?
nucleolar preribosome, small subunit precursor ?
0

BLAST
PF14_0585 ?
ribosomal protein S28e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YOR167C, clust.pair #31
YLR264W ?
telomere maintenance ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
5e-12

BLAST
MAL13P1.209 ?
60S ribosomal subunit porotein L18, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
** also with: YOL120C, clust.pair #29
YNL301C ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
8.00001e-42

BLAST
PF07_0088 ?
40S ribosomal protein S5, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
small ribosomal subunit (IEA) ?
YJR123W ?
structural constituent of ribosome ?
cytosolic small ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
0

BLAST
PFL1745c ?
clustered-asparagine-rich protein

nucleic acid binding (IEA) ?
RNA binding ?
YER165W ?
nucleus ?
cytoplasm ?
ribosome ?
regulation of translational initiation ?
poly(A) binding ?
4e-08

BLAST
PFL0665c ?
RNA polymerase subunit 8c, putative

nucleic acid binding (IEA) ?
DNA-directed RNA polymerase activity ?
transcription (IEA) ?
transcription initiation ?
YOR224C ?
DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase II, core complex ?
DNA-directed RNA polymerase III complex ?
DNA-directed RNA polymerase I complex ?
transcription from RNA polymerase I promoter ?
transcription from RNA polymerase II promoter ?
transcription from RNA polymerase III promoter ?
1e-14

BLAST
PFC0400w ?
60S Acidic ribosomal protein P2

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
translational elongation ?
large ribosomal subunit ?
** also with: YDR382W, clust.pair #31
YOL039W ?
structural constituent of ribosome ?
cytosolic large ribosomal subunit (sensu Eukaryota) ?
protein biosynthesis ?
translational elongation ?
2e-09

BLAST
PFL0900c ?
arginyl-tRNA synthetase, putative

arginine-tRNA ligase activity ?
ATP binding (IEA) ?
arginyl-tRNA aminoacylation ?
apicoplast ?
YDR341C ?
arginine-tRNA ligase activity ?
cytoplasm ?
mitochondrion ?
protein biosynthesis ?
3.9937e-43

BLAST

Cluster Pair #34: 8 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF13_0349 ?
nucleoside diphosphate kinase b%3B putative

nucleoside diphosphate kinase activity ?
ATP binding ?
GTP biosynthesis ?
UTP biosynthesis ?
CTP biosynthesis ?
YKL067W ?
nucleoside diphosphate kinase activity ?
mitochondrion ?
mitochondrial intermembrane space ?
cytosol ?
purine nucleotide biosynthesis ?
nucleoside diphosphate phosphorylation ?
DNA metabolism ?
nucleotide metabolism ?
nucleoside triphosphate biosynthesis ?
RNA metabolism ?
0

BLAST
PF08_0038 ?
hypothetical protein

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
protein biosynthesis (IEA) ?
YJL115W ?
chromatin assembly complex ?
DNA replication-dependent nucleosome assembly ?
DNA replication-independent nucleosome assembly ?
nucleosome disassembly ?
chromatin silencing at telomere ?
histone acetylation ?
chromatin silencing at silent mating-type cassette ?
histone binding ?
0.032

BLAST
PF08_0125 ?
tubulin gamma chain

microtubule cytoskeleton organization and biogenesis ?
GTPase activity (IEA) ?
structural molecule activity (IEA) ?
structural constituent of cytoskeleton ?
GTP binding (IEA) ?
microtubule organizing center ?
microtubule (IEA) ?
microtubule-based movement (IEA) ?
protein complex (IEA) ?
protein polymerization (IEA) ?
YLR212C ?
gamma-tubulin complex (sensu Saccharomyces) ?
structural constituent of cytoskeleton ?
inner plaque of spindle pole body ?
outer plaque of spindle pole body ?
microtubule nucleation ?
mitotic spindle organization and biogenesis in nucleus ?
0

BLAST
PF11_0117 ?
replication factor C subunit 5, putative

DNA binding (IEA) ?
DNA replication factor C complex ?
DNA replication ?
DNA strand elongation ?
protein complex (IEA) ?
YBR087W ?
DNA clamp loader activity ?
DNA replication factor C complex ?
leading strand elongation ?
mismatch repair ?
sister chromatid cohesion ?
1e-38

BLAST
PFD0685c ?
chromosome associated protein, putative

nuclear chromosome ?
protein binding (IEA) ?
ATP binding ?
chromosome (IEA) ?
chromosome organization and biogenesis (sensu Eukaryota) ?
ATPase activity (IEA) ?
chromosome organization and biogenesis (IEA) ?
YJL074C ?
nuclear cohesin complex ?
nucleus ?
mitotic sister chromatid cohesion ?
synaptonemal complex formation ?
ATPase activity ?
sporulation (sensu Fungi) ?
0

BLAST
PF14_0602 ?
DNA polymerase alpha subunit, putative

DNA binding (IEA) ?
DNA-directed DNA polymerase activity (IEA) ?
alpha DNA polymerase activity ?
nucleus (IEA) ?
alpha DNA polymerase:primase complex ?
DNA replication (IEA) ?
DNA replication, synthesis of RNA primer ?
YBL035C ?
alpha DNA polymerase activity ?
nucleus ?
nuclear membrane ?
alpha DNA polymerase:primase complex ?
DNA replication initiation ?
lagging strand elongation ?
telomere capping ?
2e-16

BLAST
MAL8P1.18 ?
hypothetical protein

nucleic acid binding (IEA) ?
RNA binding (IEA) ?
apicoplast ?
YJL074C ?
nuclear cohesin complex ?
nucleus ?
mitotic sister chromatid cohesion ?
synaptonemal complex formation ?
ATPase activity ?
sporulation (sensu Fungi) ?
0.012

BLAST
PF11_0087 ?
Rad51 homolog, putative

recombinase activity ?
nucleotide binding (IEA) ?
DNA binding ?
damaged DNA binding ?
ATP binding ?
nucleus ?
DNA metabolism (IEA) ?
DNA repair ?
DNA recombination ?
DNA-dependent ATPase activity ?
nucleoside-triphosphatase activity (IEA) ?
YER095W ?
recombinase activity ?
nuclear chromosome ?
meiotic joint molecule formation ?
telomerase-independent telomere maintenance ?
condensed nuclear chromosome ?
meiotic recombination ?
DNA-dependent ATPase activity ?
heteroduplex formation ?
strand invasion ?
double-strand break repair via single-strand annealing ?
0

BLAST

Cluster Pair #35: 4 gene pairs.

P.falciparumS.cerevisiaeBlast evalue
PF14_0451 ?
mitochondrial ribosomal protein S14 precursor, putative

structural constituent of ribosome ?
mitochondrial small ribosomal subunit ?
protein biosynthesis ?
YPR166C ?
structural constituent of ribosome ?
mitochondrion ?
mitochondrial small ribosomal subunit ?
protein biosynthesis ?
5e-06

BLAST
MAL13P1.281 ?
glutamate--tRNA ligase, putative

tRNA ligase activity (IEA) ?
glutamate-tRNA ligase activity ?
ATP binding (IEA) ?
cytoplasm (IEA) ?
protein biosynthesis (IEA) ?
glutamyl-tRNA aminoacylation ?
aminoacyl-tRNA synthetase multienzyme complex (IEA) ?
apicoplast ?
YOL033W ?
glutamate-tRNA ligase activity ?
mitochondrion ?
protein biosynthesis ?
glutamyl-tRNA aminoacylation ?
0

BLAST
PFL1590c ?
elongation factor g, putative

translation elongation factor activity ?
GTP binding ?
mitochondrion ?
protein biosynthesis (IEA) ?
translational elongation ?
YLR069C ?
translation elongation factor activity ?
mitochondrion ?
translational elongation ?
0

BLAST
PFL2180w ?
50S ribosomal protein L3, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrial large ribosomal subunit ?
ribosome (IEA) ?
protein biosynthesis ?
YGR220C ?
ribosomal large subunit assembly and maintenance ?
peptidyltransferase activity ?
structural constituent of ribosome ?
mitochondrion ?
mitochondrial large ribosomal subunit ?
protein biosynthesis ?
3e-25

BLAST