Leroch - Spellman co-coexpression analysis

33 cluster pairs

Cluster Pair #0: 11 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF14_0254 ?
DNA mismatch repair protein Msh2p, putative

damaged DNA binding ?
ATP binding (IEA) ?
DNA metabolic process (IEA) ?
mismatch repair ?
YOL090W ?
nuclear chromosome ?
four-way junction DNA binding ?
Y-form DNA binding ?
loop DNA binding ?
double-strand/single-strand DNA junction binding ?
meiotic mismatch repair ?
removal of nonhomologous ends ?
ATP binding ?
nucleus ?
mismatch repair ?
DNA recombination ?
meiotic gene conversion ?
mitotic recombination ?
ATPase activity ?
chromatin silencing at silent mating-type cassette ?
DNA insertion or deletion binding ?
guanine/thymine mispair binding ?
single base insertion or deletion binding ?
0

BLAST
PF13_0328 ?
proliferating cell nuclear antigen

DNA binding (IEA) ?
nucleus (IEA) ?
DNA replication factor C complex (IEA) ?
regulation of DNA replication (IEA) ?
DNA polymerase processivity factor activity (IEA) ?
PCNA complex (IEA) ?
YBR088C ?
nucleus ?
replication fork ?
leading strand elongation ?
lagging strand elongation ?
mutagenesis ?
base-excision repair ?
nucleotide-excision repair ?
mismatch repair ?
postreplication repair ?
chromatin silencing at telomere ?
DNA polymerase processivity factor activity ?
chromatin silencing at silent mating-type cassette ?
PCNA complex ?
2e-37

BLAST
PFE0270c ?
DNA repair protein, putative

damaged DNA binding ?
ATP binding (IEA) ?
DNA metabolic process (IEA) ?
DNA repair ?
mismatch repair (IEA) ?
YDR097C ?
four-way junction DNA binding ?
meiotic mismatch repair ?
ATP binding ?
nucleus ?
mismatch repair ?
ATPase activity ?
guanine/thymine mispair binding ?
single base insertion or deletion binding ?
0

BLAST
PF08_0125 ?
tubulin gamma chain

microtubule cytoskeleton organization and biogenesis ?
GTPase activity (IEA) ?
structural molecule activity (IEA) ?
structural constituent of cytoskeleton ?
GTP binding (IEA) ?
microtubule organizing center ?
microtubule (IEA) ?
microtubule-based movement (IEA) ?
protein complex (IEA) ?
protein polymerization (IEA) ?
YLR212C ?
gamma-tubulin small complex, spindle pole body ?
structural constituent of cytoskeleton ?
inner plaque of spindle pole body ?
outer plaque of spindle pole body ?
microtubule nucleation ?
mitotic spindle organization and biogenesis in nucleus ?
0

BLAST
PFI0235w ?
replication factor A-related protein, putative

nucleic acid binding (IEA) ?
YAR007C ?
double-strand break repair via homologous recombination ?
chromosome, telomeric region ?
damaged DNA binding ?
single-stranded DNA binding ?
nucleus ?
DNA replication factor A complex ?
cytoplasm ?
DNA unwinding during replication ?
DNA replication, synthesis of RNA primer ?
DNA strand elongation during DNA replication ?
nucleotide-excision repair ?
postreplication repair ?
DNA recombination ?
1e-28

BLAST
PFI0530c ?
DNA primase, large subunit, putative

DNA primase activity (IEA) ?
alpha DNA polymerase:primase complex (IEA) ?
DNA replication, synthesis of RNA primer (IEA) ?
YKL045W ?
DNA synthesis during DNA repair ?
DNA primase activity ?
nucleus ?
nuclear envelope ?
alpha DNA polymerase:primase complex ?
DNA replication ?
DNA replication, synthesis of RNA primer ?
DNA replication initiation ?
lagging strand elongation ?
9.80909e-45

BLAST
PFL2330w ?
hypothetical protein

membrane ?
apicoplast ?
YCL024W ?
septin checkpoint ?
septin ring assembly ?
protein kinase activity ?
cellular bud neck ?
protein amino acid phosphorylation ?
budding cell bud growth ?
axial cellular bud site selection ?
0.28

BLAST
PFD0470c ?
replication factor a protein, putative

nucleic acid binding (IEA) ?
DNA replication factor A complex ?
DNA replication ?
DNA-dependent DNA replication ?
YAR007C ?
double-strand break repair via homologous recombination ?
chromosome, telomeric region ?
damaged DNA binding ?
single-stranded DNA binding ?
nucleus ?
DNA replication factor A complex ?
cytoplasm ?
DNA unwinding during replication ?
DNA replication, synthesis of RNA primer ?
DNA strand elongation during DNA replication ?
nucleotide-excision repair ?
postreplication repair ?
DNA recombination ?
9.94922e-44

BLAST
PF14_0680 ?
hypothetical protein

membrane ?
YGR221C ?
cellular bud tip ?
cellular bud neck ?
budding cell bud growth ?
3.2

BLAST
PF11_0249 ?
hypothetical protein

ATP binding (IEA) ?
chromosome (IEA) ?
chromosome organization and biogenesis (IEA) ?
YOL034W ?
nucleus ?
DNA repair ?
cell proliferation ?
Smc5-Smc6 complex ?
1e-14

BLAST
PFE1255w ?
hypothetical protein

ATP binding (IEA) ?
chromosome (IEA) ?
chromosome organization and biogenesis (IEA) ?
YLR383W ?
nucleus ?
mitochondrion ?
DNA repair ?
cell proliferation ?
Smc5-Smc6 complex ?
3e-11

BLAST

Cluster Pair #1: 13 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFF1070c ?
hypothetical protein, conserved

catalytic activity (IEA) ?
iron ion binding (IEA) ?
YBR142W ?
ribosomal large subunit assembly and maintenance ?
ATP-dependent RNA helicase activity ?
nucleolus ?
rRNA processing ?
ribosome biogenesis and assembly ?
2.8

BLAST
PF14_0473 ?
3%27-5%27 exonuclease, putative

nucleic acid binding (IEA) ?
intracellular (IEA) ?
3'-5' exonuclease activity (IEA) ?
YOR001W ?
3'-5'-exoribonuclease activity ?
nuclear exosome (RNase complex) ?
mRNA catabolic process ?
ribosome biogenesis and assembly ?
polyadenylation-dependent ncRNA catabolic process ?
1e-12

BLAST
MAL13P1.93 ?
hypothetical protein

YPR144C ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
Noc4p-Nop14p complex ?
ribosome biogenesis and assembly ?
ribosomal small subunit biogenesis and assembly ?
0.009

BLAST
PF11_0353 ?
hypothetical protein

YNL227C ?
ATPase activator activity ?
cytoplasm ?
mitochondrion ?
cytosol ?
endocytosis ?
regulation of cell size ?
Hsp70/Hsc70 protein regulator activity ?
ribosomal large subunit biogenesis and assembly ?
0.038

BLAST
PFE1240w ?
hypothetical protein, conserved

catalytic activity (IEA) ?
iron ion binding (IEA) ?
YPL207W ?
endoplasmic reticulum ?
0

BLAST
PFF1500c ?
DEAD%2FDEAH box ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
RNA metabolic process ?
YMR290C ?
RNA binding ?
ATP-dependent RNA helicase activity ?
nuclear envelope ?
nucleolus ?
rRNA processing ?
RNA-dependent ATPase activity ?
ribosome biogenesis and assembly ?
0

BLAST
PF13_0109 ?
N2,N2-dimethylguanosine tRNA methyltransferase, putative

RNA binding (IEA) ?
tRNA (guanine-N2-)-methyltransferase activity ?
tRNA modification ?
tRNA processing (IEA) ?
apicoplast ?
YDR120C ?
tRNA (guanine-N2-)-methyltransferase activity ?
nuclear envelope ?
nuclear inner membrane ?
mitochondrion ?
tRNA methylation ?
ribosome biogenesis and assembly ?
3e-13

BLAST
PF07_0121 ?
hypothetical protein, conserved

YHR170W ?
ribosomal large subunit assembly and maintenance ?
ribosomal large subunit export from nucleus ?
RNA binding ?
protein binding ?
cytosol ?
ribosome biogenesis and assembly ?
2.94273e-44

BLAST
PF10_0200 ?
hypothetical protein, conserved

YNL132W ?
nucleolus ?
ribosome biogenesis and assembly ?
2e-39

BLAST
PF14_0185 ?
ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
also with YHR065C, clust.pair #2
YMR290C ?
RNA binding ?
ATP-dependent RNA helicase activity ?
nuclear envelope ?
nucleolus ?
rRNA processing ?
RNA-dependent ATPase activity ?
ribosome biogenesis and assembly ?
5e-10

BLAST
PF13_0177 ?
ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YHR169W ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
0

BLAST
PF14_0055 ?
hypothetical protein, conserved

YMR049C ?
nucleus ?
nucleolus ?
rRNA processing ?
2e-24

BLAST
PF10_0278 ?
hypothetical protein, conserved

YKR081C ?
ribosomal large subunit assembly and maintenance ?
nucleolus ?
5S rRNA binding ?
7S RNA binding ?
rRNA binding ?
processing of 27S pre-rRNA ?
ribosome biogenesis and assembly ?
2e-05

BLAST

Cluster Pair #2: 11 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFB0860c ?
RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YHR065C ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
0

BLAST
PF11_0471 ?
hypothetical protein

YCR072C ?
ribosomal large subunit assembly and maintenance ?
nucleolus ?
ribosome ?
ribosome biogenesis and assembly ?
2.8026e-45

BLAST
PF14_0185 ?
ATP-dependent RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
also with YMR290C, clust.pair #1
YHR065C ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
1e-09

BLAST
PF11_0090 ?
hypothetical protein

intracellular (IEA) ?
nucleolus (IEA) ?
cell proliferation (IEA) ?
YGR103W ?
nucleus ?
nucleolus ?
cell cycle ?
cell proliferation ?
maturation of SSU-rRNA ?
ribosome biogenesis and assembly ?
ribosomal large subunit biogenesis and assembly ?
0

BLAST
MAL8P1.19 ?
hypothetical protein, conserved

nucleic acid binding (IEA) ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
apicoplast ?
YLL008W ?
ribosomal large subunit assembly and maintenance ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
7e-32

BLAST
MAL8P1.92 ?
ATPase, putative

nucleotide binding (IEA) ?
ATP binding (IEA) ?
ATPase activity ?
nucleoside-triphosphatase activity (IEA) ?
YLL034C ?
ribosomal large subunit export from nucleus ?
nucleus ?
nucleolus ?
ATPase activity ?
0

BLAST
PF14_0661 ?
hypothetical protein, conserved

nucleic acid binding (IEA) ?
YOR145C ?
nucleus ?
nucleolus ?
rRNA processing ?
protein complex assembly ?
ribosome biogenesis and assembly ?
unfolded protein binding ?
0

BLAST
PF14_0183 ?
RNA helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YJL033W ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
0

BLAST
PF14_0072 ?
hypothetical protein, conserved

YNR046W ?
tRNA (guanine-N2-)-methyltransferase activity ?
nucleus ?
nucleolus ?
cytoplasm ?
zinc ion binding ?
tRNA methylation ?
2e-09

BLAST
PFI0635c ?
hypothetical protein

YML093W ?
small nucleolar ribonucleoprotein complex ?
maturation of SSU-rRNA ?
snoRNA binding ?
ribosome biogenesis and assembly ?
0.01

BLAST
MAL13P1.334 ?
hypothetical protein

YJR002W ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
maturation of SSU-rRNA ?
small subunit processome ?
ribosome biogenesis and assembly ?
0.082

BLAST

Cluster Pair #3: 4 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF11_0189 ?
hypothetical protein

YOL098C ?
cytoplasm ?
6.02558e-44

BLAST
PF11_0225 ?
PfGCN20

nucleotide binding (IEA) ?
ATP binding ?
regulation of translation ?
transport ?
membrane ?
ATPase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
ATPase activity, coupled to transmembrane movement of substances ?
YFR009W ?
cytosol ?
regulation of translational elongation ?
ATPase activity ?
0

BLAST
PF13_0261 ?
ATP binding protein, putative

ATP binding ?
YLR243W ?
signal sequence binding ?
2e-24

BLAST
PFE1320w ?
hypothetical protein

intracellular (IEA) ?
RNA processing (IEA) ?
YMR061W ?
RNA binding ?
nucleus ?
mitochondrion ?
mRNA cleavage factor complex ?
mRNA polyadenylation ?
mRNA cleavage ?
protein heterodimerization activity ?
6e-05

BLAST

Cluster Pair #4: 11 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF14_0716 ?
Proteosome subunit alpha type 1, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex ?
ubiquitin-dependent protein catabolic process ?
YMR314W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolic process ?
proteasome core complex, alpha-subunit complex ?
3.00018e-42

BLAST
PF13_0033 ?
26S proteasome regulatory subunit, putative

nucleotide binding (IEA) ?
nucleic acid binding (IEA) ?
endopeptidase activity ?
ATP binding (IEA) ?
nucleus (IEA) ?
cytoplasm (IEA) ?
proteasome regulatory particle ?
ubiquitin-dependent protein catabolic process ?
hydrolase activity (IEA) ?
ATPase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
protein catabolic process (IEA) ?
YOR259C ?
endopeptidase activity ?
nucleus ?
ubiquitin-dependent protein catabolic process ?
proteasome regulatory particle, base subcomplex ?
ATPase activity ?
0

BLAST
MAL8P1.142 ?
proteasome beta-subunit

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex ?
ubiquitin-dependent protein catabolic process (IEA) ?
YFR050C ?
endopeptidase activity ?
ubiquitin-dependent protein catabolic process ?
proteasome core complex, beta-subunit complex ?
5e-26

BLAST
PF13_0063 ?
26S proteasome regulatory subunit 7, putative

nucleotide binding (IEA) ?
endopeptidase activity ?
ATP binding (IEA) ?
nucleus (IEA) ?
cytoplasm (IEA) ?
proteasome regulatory particle ?
ubiquitin-dependent protein catabolic process ?
hydrolase activity (IEA) ?
ATPase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
protein catabolic process (IEA) ?
YKL145W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolic process ?
proteasome regulatory particle, base subcomplex ?
ATPase activity ?
0

BLAST
PF14_0025 ?
proteosome subunit, putative

endopeptidase activity ?
proteasome regulatory particle ?
proteolysis ?
YDL097C ?
structural molecule activity ?
ubiquitin-dependent protein catabolic process ?
proteasome regulatory particle, lid subcomplex ?
8e-21

BLAST
PF07_0113 ?
hypothetical protein

apicoplast ?
YJL036W ?
pre-autophagosomal structure ?
cytoplasm ?
protein targeting to vacuole ?
lipid binding ?
phosphatidylinositol 3-phosphate binding ?
0.008

BLAST
MAL13P1.270 ?
proteasome subunit, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex ?
ubiquitin-dependent protein catabolic process ?
YOL038W ?
endopeptidase activity ?
mitochondrion ?
cytosol ?
ubiquitin-dependent protein catabolic process ?
proteasome core complex, alpha-subunit complex ?
0

BLAST
MAL13P1.190 ?
proteasome regulatory component, putative

endopeptidase activity ?
proteasome regulatory particle ?
ubiquitin-dependent protein catabolic process ?
YER021W ?
ubiquitin-dependent protein catabolic process ?
proteasome regulatory particle, lid subcomplex ?
0

BLAST
PFC0520w ?
26S proteasome regulatory subunit S14, putative

proteasome regulatory particle ?
ubiquitin-dependent protein catabolic process ?
YFR052W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolic process ?
proteasome regulatory particle, lid subcomplex ?
4e-14

BLAST
MAL8P1.128 ?
proteasome subunit alpha, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex ?
ubiquitin-dependent protein catabolic process ?
YGL011C ?
endopeptidase activity ?
mitochondrion ?
ubiquitin-dependent protein catabolic process ?
proteasome core complex, alpha-subunit complex ?
1e-34

BLAST
PF11_0303 ?
26S proteasome regulatory complex subunit, putative

proteasome complex ?
endopeptidase activity ?
proteolysis ?
YPR108W ?
structural molecule activity ?
ubiquitin-dependent protein catabolic process ?
proteasome regulatory particle, lid subcomplex ?
0

BLAST

Cluster Pair #5: 12 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFF0940c ?
cell division cycle protein 48 homologue, putative

nucleotide binding (IEA) ?
ATP-dependent peptidase activity (IEA) ?
serine-type endopeptidase activity (IEA) ?
ATP binding (IEA) ?
microsome ?
proteolysis (IEA) ?
hydrolase activity (IEA) ?
ATPase activity ?
nucleoside-triphosphatase activity (IEA) ?
YDL126C ?
nucleus ?
endoplasmic reticulum membrane ?
microsome ?
cytosol ?
ubiquitin-dependent protein catabolic process ?
vesicle fusion ?
apoptosis ?
cell cycle ?
protein transport ?
ATPase activity ?
ER-associated protein catabolic process ?
0

BLAST
PF13_0282 ?
proteasome subunit, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex ?
ubiquitin-dependent protein catabolic process ?
YGR135W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolic process ?
proteasome core complex, alpha-subunit complex ?
filamentous growth ?
0

BLAST
PFE0915c ?
proteasome subunit beta type 1

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex ?
ubiquitin-dependent protein catabolic process ?
YBL041W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolic process ?
proteasome core complex, beta-subunit complex ?
9e-35

BLAST
PF07_0112 ?
proteasome subunit alpha type 5, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex (IEA) ?
ubiquitin-dependent protein catabolic process ?
proteasome core complex, alpha-subunit complex ?
YGR253C ?
endopeptidase activity ?
ubiquitin-dependent protein catabolic process ?
response to stress ?
proteasome core complex, alpha-subunit complex ?
ascospore formation ?
0

BLAST
PFE0150c ?
4-diphosphocytidyl-2c-methyl-D-erythritol kinase %28CMK%29, putative

ATP binding (IEA) ?
isoprenoid biosynthetic process ?
kinase activity (IEA) ?
phosphorylation (IEA) ?
apicoplast ?
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity ?
YLR149C ?
0.086

BLAST
PFL1300c ?
hypothetical protein

YEL052W ?
mitochondrion ?
ATPase activity ?
0.23

BLAST
MAL13P1.343 ?
proteasome regulatory subunit, putative

proteasome regulatory particle ?
ubiquitin-dependent protein catabolic process ?
YFR004W ?
endopeptidase activity ?
nucleus ?
ubiquitin-dependent protein catabolic process ?
proteasome regulatory particle, lid subcomplex ?
0

BLAST
PFA0450c ?
mRNA cleavage factor-like protein, putative

YNL173C ?
pheromone-dependent signal transduction during conjugation with cellular fusion ?
plasma membrane ?
0.017

BLAST
PF14_0632 ?
26S proteasome subunit, putative

endopeptidase activity ?
proteasome regulatory particle ?
ubiquitin-dependent protein catabolic process ?
YIL075C ?
endopeptidase activity ?
nucleus ?
ubiquitin-dependent protein catabolic process ?
proteasome regulatory particle, base subcomplex ?
protein binding, bridging ?
0

BLAST
PFL1245w ?
ubiquitin-activating enzyme e1, putative

catalytic activity (IEA) ?
ubiquitin activating enzyme activity ?
protein modification process (IEA) ?
ubiquitin cycle ?
small protein activating enzyme activity (IEA) ?
YKL210W ?
ubiquitin activating enzyme activity ?
nucleus ?
cytoplasm ?
ubiquitin cycle ?
0

BLAST
PFA0400c ?
beta3 proteasome subunit, putative

endopeptidase activity ?
threonine endopeptidase activity (IEA) ?
proteasome core complex ?
ubiquitin-dependent protein catabolic process ?
YER094C ?
endopeptidase activity ?
ubiquitin-dependent protein catabolic process ?
proteasome core complex, beta-subunit complex ?
0

BLAST
PF11_0314 ?
26S protease subunit regulatory subunit 6a, putative

nucleotide binding (IEA) ?
proteasome complex ?
endopeptidase activity ?
ATP binding (IEA) ?
nucleus (IEA) ?
cytoplasm (IEA) ?
proteolysis ?
hydrolase activity (IEA) ?
ATPase activity ?
nucleoside-triphosphatase activity (IEA) ?
protein catabolic process (IEA) ?
YOR117W ?
endopeptidase activity ?
ubiquitin-dependent protein catabolic process ?
proteasome regulatory particle, base subcomplex ?
ATPase activity ?
0

BLAST

Cluster Pair #6: 6 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFB0175c ?
hypothetical protein

YAL025C ?
nucleolus ?
processing of 27S pre-rRNA ?
ribosome biogenesis and assembly ?
ribosomal large subunit biogenesis and assembly ?
1e-25

BLAST
PF11_0445 ?
DNA-directed RNA polymerase I, putative

DNA binding (IEA) ?
DNA-directed RNA polymerase activity (IEA) ?
transcription (IEA) ?
protein dimerization activity (IEA) ?
YPR110C ?
DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase III complex ?
DNA-directed RNA polymerase I complex ?
transcription from RNA polymerase I promoter ?
transcription from RNA polymerase III promoter ?
ribosome biogenesis and assembly ?
9.94922e-44

BLAST
PFE1310c ?
hypothetical protein

YPR169W ?
nucleus ?
nucleolus ?
protein monoubiquitination ?
0.0001

BLAST
PF13_0136 ?
hypothetical protein

YDR361C ?
ribosomal large subunit export from nucleus ?
nucleus ?
cytoplasm ?
protein export from nucleus ?
0.28

BLAST
PF07_0027 ?
DNA-directed RNA polymerase 2 8.2 kDa polypeptide, putative

DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase II, core complex ?
transcription (IEA) ?
transcription from RNA polymerase II promoter ?
YOR210W ?
DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase II, core complex ?
DNA-directed RNA polymerase III complex ?
DNA-directed RNA polymerase I complex ?
transcription from RNA polymerase I promoter ?
transcription from RNA polymerase II promoter ?
transcription from RNA polymerase III promoter ?
2e-17

BLAST
PFI0475w ?
small nuclear ribonucleoprotein %28snRNP%29, putative

nucleus (IEA) ?
small nucleolar ribonucleoprotein complex (IEA) ?
mRNA processing (IEA) ?
ribonucleoprotein complex (IEA) ?
YLR147C ?
commitment complex ?
nuclear mRNA splicing, via spliceosome ?
mRNA binding ?
snRNP U5 ?
snRNP U1 ?
RNA splicing factor activity, transesterification mechanism ?
U4/U6 x U5 tri-snRNP complex ?
4e-16

BLAST

Cluster Pair #7: 18 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
MAL7P1.24 ?
hypothetical protein, conserved

intracellular (IEA) ?
YER126C ?
nucleus ?
ribosome biogenesis and assembly ?
ribosomal large subunit biogenesis and assembly ?
0

BLAST
PF14_0429 ?
RNA helicase, putative

nucleic acid binding (IEA) ?
helicase activity ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
also with YMR290C, clust.pair #7 also with YLL008W, clust.pair #8 also with YJL033W, clust.pair #8 also with YHR065C, clust.pair #8
YHR169W ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
3e-29

BLAST
PF14_0429 ?
RNA helicase, putative

nucleic acid binding (IEA) ?
helicase activity ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
also with YHR169W, clust.pair #7 also with YLL008W, clust.pair #8 also with YJL033W, clust.pair #8 also with YHR065C, clust.pair #8
YMR290C ?
RNA binding ?
ATP-dependent RNA helicase activity ?
nuclear envelope ?
nucleolus ?
rRNA processing ?
RNA-dependent ATPase activity ?
ribosome biogenesis and assembly ?
8e-29

BLAST
PF14_0100 ?
cytidine triphosphate synthetase

catalytic activity (IEA) ?
CTP synthase activity ?
pyrimidine base metabolic process ?
pyrimidine nucleotide biosynthetic process (IEA) ?
YBL039C ?
CTP synthase activity ?
cytosol ?
CTP biosynthetic process ?
phospholipid biosynthetic process ?
pyrimidine base biosynthetic process ?
0

BLAST
PF13_0309 ?
hypothetical protein

YLR409C ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
snoRNA binding ?
ribosome biogenesis and assembly ?
1e-17

BLAST
PFL1345c ?
hypothetical protein, conserved

catalytic activity (IEA) ?
iron ion binding (IEA) ?
membrane ?
YPL086C ?
histone acetyltransferase activity ?
nucleus ?
cytoplasm ?
regulation of transcription from RNA polymerase II promoter ?
tRNA modification ?
transcription elongation factor complex ?
0

BLAST
PF08_0065 ?
hypothetical protein, conserved

YMR131C ?
nucleolus ?
ribosome biogenesis and assembly ?
5e-33

BLAST
PF14_0436 ?
helicase, truncated, putative

nucleic acid binding (IEA) ?
helicase activity ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YNL112W ?
mRNA catabolic process, nonsense-mediated decay ?
RNA helicase activity ?
nucleus ?
cytoplasm ?
mitochondrion ?
0

BLAST
PF13_0310 ?
hypothetical protein

YDL153C ?
nucleus ?
small nucleolar ribonucleoprotein complex ?
establishment and/or maintenance of chromatin architecture ?
maturation of SSU-rRNA ?
snoRNA binding ?
ribosome biogenesis and assembly ?
2e-06

BLAST
PF14_0221 ?
hypothetical protein, conserved

GTP binding (IEA) ?
YNR053C ?
ribosomal large subunit export from nucleus ?
GTPase activity ?
nucleus ?
nucleoplasm ?
nucleolus ?
ribosome biogenesis and assembly ?
ribosome assembly ?
0

BLAST
PF10_0054 ?
hypothetical protein

YIL091C ?
RNA helicase activity ?
nucleus ?
nucleolus ?
2e-19

BLAST
PF11_0275 ?
hypothetical protein

YLR409C ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
snoRNA binding ?
ribosome biogenesis and assembly ?
0.083

BLAST
PFE1390w ?
RNA helicase-1

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YNL112W ?
mRNA catabolic process, nonsense-mediated decay ?
RNA helicase activity ?
nucleus ?
cytoplasm ?
mitochondrion ?
0

BLAST
PF14_0494 ?
hypothetical protein, conserved

mitochondrion ?
YDL060W ?
nucleolus ?
cytoplasm ?
rRNA processing ?
ribosome biogenesis and assembly ?
ribonucleoprotein binding ?
2e-18

BLAST
PFL1175w ?
hypothetical protein

YJL069C ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
ribosome biogenesis and assembly ?
7e-05

BLAST
PF10_0197 ?
hypothetical protein

apicoplast ?
YNL061W ?
nucleolus ?
rRNA processing ?
RNA methyltransferase activity ?
S-adenosylmethionine-dependent methyltransferase activity ?
ribosome biogenesis and assembly ?
1e-06

BLAST
MAL7P1.113 ?
DEAD box helicase, putative

nucleic acid binding (IEA) ?
RNA binding ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding ?
ATP-dependent helicase activity (IEA) ?
RNA metabolic process ?
also with YMR290C, clust.pair #7
YKR024C ?
ribosomal large subunit assembly and maintenance ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
5e-26

BLAST
MAL7P1.113 ?
DEAD box helicase, putative

nucleic acid binding (IEA) ?
RNA binding ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding ?
ATP-dependent helicase activity (IEA) ?
RNA metabolic process ?
also with YKR024C, clust.pair #7
YMR290C ?
RNA binding ?
ATP-dependent RNA helicase activity ?
nuclear envelope ?
nucleolus ?
rRNA processing ?
RNA-dependent ATPase activity ?
ribosome biogenesis and assembly ?
1e-24

BLAST

Cluster Pair #8: 17 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF07_0067 ?
hypothetical protein

YGR245C ?
nucleus ?
traversing start control point of mitotic cell cycle ?
actin cytoskeleton organization and biogenesis ?
ribosome biogenesis and assembly ?
ribosome assembly ?
1e-09

BLAST
PFL2475w ?
DEAD%2FDEAH box helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
RNA metabolic process ?
YLL008W ?
ribosomal large subunit assembly and maintenance ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
0

BLAST
PF14_0068 ?
fibrillarin, putative

RNA binding (IEA) ?
nucleus (IEA) ?
small nucleolar ribonucleoprotein complex ?
mitochondrion ?
rRNA processing ?
YDL014W ?
ribosomal large subunit assembly and maintenance ?
rRNA modification ?
RNA methylation ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
ribosome ?
methyltransferase activity ?
maturation of SSU-rRNA ?
snoRNA 3'-end processing ?
ribosome biogenesis and assembly ?
0

BLAST
PF14_0429 ?
RNA helicase, putative

nucleic acid binding (IEA) ?
helicase activity ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
also with YHR169W, clust.pair #7 also with YMR290C, clust.pair #7 also with YJL033W, clust.pair #8 also with YHR065C, clust.pair #8
YLL008W ?
ribosomal large subunit assembly and maintenance ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
4e-30

BLAST
PF14_0429 ?
RNA helicase, putative

nucleic acid binding (IEA) ?
helicase activity ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
also with YHR169W, clust.pair #7 also with YMR290C, clust.pair #7 also with YLL008W, clust.pair #8 also with YHR065C, clust.pair #8
YJL033W ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
2e-29

BLAST
PF14_0429 ?
RNA helicase, putative

nucleic acid binding (IEA) ?
helicase activity ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
also with YHR169W, clust.pair #7 also with YMR290C, clust.pair #7 also with YLL008W, clust.pair #8 also with YJL033W, clust.pair #8
YHR065C ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
1e-28

BLAST
PFF1030w ?
hypothetical protein, conserved

RNA binding (IEA) ?
YDR496C ?
mRNA binding ?
nucleus ?
nucleolus ?
regulation of transcription, mating-type specific ?
specific transcriptional repressor activity ?
ribosome biogenesis and assembly ?
0.0006

BLAST
PF14_0456 ?
hypothetical protein, conserved

YLR129W ?
small nucleolar ribonucleoprotein complex ?
maturation of SSU-rRNA ?
snoRNA binding ?
ribosome biogenesis and assembly ?
5.04467e-44

BLAST
PFE1115c ?
s-adenosylmethionine-dependent methyltransferase, putative

S-adenosylmethionine-dependent methyltransferase activity ?
YCR047C ?
cellular bud site selection ?
nucleus ?
cytoplasm ?
S-adenosylmethionine-dependent methyltransferase activity ?
0

BLAST
PFI1235w ?
hypothetical protein

YDR083W ?
telomere maintenance ?
nucleolus ?
rRNA processing ?
methyltransferase activity ?
ribosome biogenesis and assembly ?
6e-24

BLAST
PF14_0292 ?
hypothetical protein, conserved

GTP binding (IEA) ?
YGL099W ?
ribosome export from nucleus ?
conjugation with cellular fusion ?
GTPase activity ?
cytoplasm ?
ascospore formation ?
ribosome biogenesis and assembly ?
2e-30

BLAST
PF14_0174 ?
hypothetical protein, conserved

RNA binding (IEA) ?
pseudouridylate synthase activity (IEA) ?
RNA processing (IEA) ?
YLR175W ?
pseudouridylate synthase activity ?
nucleolus ?
rRNA pseudouridine synthesis ?
box H/ACA snoRNP complex ?
ribosome biogenesis and assembly ?
0

BLAST
MAL13P1.341 ?
hypothetical protein, conserved

YKL009W ?
telomere maintenance ?
nucleus ?
nucleolus ?
rRNA processing ?
mRNA catabolic process ?
ribosome biogenesis and assembly ?
ribosomal large subunit biogenesis and assembly ?
4e-06

BLAST
MAL13P1.14 ?
ATP-dependent DEAD box helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YMR128W ?
RNA helicase activity ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
mitochondrion ?
maturation of SSU-rRNA ?
ribosome biogenesis and assembly ?
9.94922e-44

BLAST
PF14_0150 ?
RNA polymerase small subunit, putative

DNA binding (IEA) ?
DNA-directed RNA polymerase activity ?
transcription ?
protein dimerization activity (IEA) ?
YNL113W ?
DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase III complex ?
DNA-directed RNA polymerase I complex ?
transcription from RNA polymerase I promoter ?
transcription from RNA polymerase III promoter ?
ribosome biogenesis and assembly ?
1e-18

BLAST
PFL2010c ?
DEAD%2FDEAH box helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
RNA metabolic process ?
YLR276C ?
ribosomal large subunit assembly and maintenance ?
ATP-dependent RNA helicase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
3e-25

BLAST
PF14_0156 ?
dimethyladenosine transferase, putative

rRNA modification ?
rRNA (adenine-N6,N6-)-dimethyltransferase activity (IEA) ?
mitochondrion ?
rRNA processing (IEA) ?
rRNA methyltransferase activity ?
S-adenosylmethionine-dependent methyltransferase activity (IEA) ?
rRNA (adenine) methyltransferase activity (IEA) ?
YPL266W ?
rRNA modification ?
rRNA (adenine-N6,N6-)-dimethyltransferase activity ?
nucleolus ?
ribosome biogenesis and assembly ?
0

BLAST

Cluster Pair #9: 5 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF14_0282 ?
hypothetical protein, conserved

acid phosphatase activity (IEA) ?
YLR410W ?
cytoplasm ?
actin cytoskeleton organization and biogenesis ?
0

BLAST
PF07_0053 ?
hypothetical protein

metalloendopeptidase activity (IEA) ?
proteolysis (IEA) ?
pathogenesis (IEA) ?
metal ion binding (IEA) ?
YDL035C ?
replicative cell aging ?
G-protein coupled receptor activity ?
plasma membrane ?
pseudohyphal growth ?
G-protein coupled receptor protein signaling pathway ?
5e-06

BLAST
PF10_0314 ?
asparagine-rich antigen

YDL035C ?
replicative cell aging ?
G-protein coupled receptor activity ?
plasma membrane ?
pseudohyphal growth ?
G-protein coupled receptor protein signaling pathway ?
0.004

BLAST
PF14_0127 ?
N-myristoyltransferase

glycylpeptide N-tetradecanoyltransferase activity ?
N-terminal protein myristoylation ?
YLR195C ?
glycylpeptide N-tetradecanoyltransferase activity ?
cytosol ?
N-terminal peptidyl-glycine N-myristoylation ?
0

BLAST
PFF0320c ?
polypyrimidine tract binding protein, putative

nucleic acid binding (IEA) ?
poly-pyrimidine tract binding ?
RNA splicing ?
YOR319W ?
nuclear mRNA splicing, via spliceosome ?
RNA binding ?
snRNP U2 ?
5e-05

BLAST

Cluster Pair #10: 6 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF14_0177 ?
DNA replication licensing factor MCM2

nucleotide binding (IEA) ?
nucleic acid binding (IEA) ?
DNA binding (IEA) ?
ATP binding (IEA) ?
nucleus (IEA) ?
DNA replication ?
DNA replication initiation (IEA) ?
DNA-dependent ATPase activity (IEA) ?
photosynthesis (IEA) ?
chlorophyll biosynthetic process (IEA) ?
magnesium chelatase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
YBL023C ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
nucleus ?
pre-replicative complex ?
cytoplasm ?
pre-replicative complex assembly ?
DNA unwinding during replication ?
DNA replication initiation ?
MCM complex ?
0

BLAST
PFL0580w ?
DNA replication licensing factor mcm5, putative

nucleic acid binding (IEA) ?
DNA binding (IEA) ?
ATP-dependent DNA helicase activity ?
ATP binding ?
nucleus (IEA) ?
pre-replicative complex ?
DNA replication initiation ?
DNA strand elongation during DNA replication ?
DNA-dependent ATPase activity ?
YLR274W ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
pre-replicative complex ?
replication fork ?
cytoplasm ?
pre-replicative complex assembly ?
DNA unwinding during replication ?
DNA replication initiation ?
establishment of chromatin silencing ?
MCM complex ?
0

BLAST
PF13_0095 ?
DNA replication licensing factor mcm4-related

nucleic acid binding (IEA) ?
DNA binding (IEA) ?
ATP binding (IEA) ?
nucleus (IEA) ?
DNA unwinding during replication ?
DNA replication initiation ?
DNA-dependent ATPase activity (IEA) ?
YPR019W ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
nucleus ?
pre-replicative complex ?
cytoplasm ?
pre-replicative complex assembly ?
DNA unwinding during replication ?
DNA replication initiation ?
MCM complex ?
0

BLAST
PFE1345c ?
minichromosome maintenance protein 3, putative

nucleotide binding (IEA) ?
nucleic acid binding (IEA) ?
DNA binding (IEA) ?
ATP binding (IEA) ?
nucleus (IEA) ?
DNA replication initiation (IEA) ?
DNA-dependent ATPase activity (IEA) ?
photosynthesis (IEA) ?
chlorophyll biosynthetic process (IEA) ?
magnesium chelatase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
YEL032W ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
nucleus ?
pre-replicative complex ?
cytoplasm ?
pre-replicative complex assembly ?
DNA unwinding during replication ?
DNA replication initiation ?
MCM complex ?
0

BLAST
PFL1370w ?
NIMA-related protein kinase %28Pfnek-1%29

protein kinase activity (IEA) ?
protein serine/threonine kinase activity ?
protein-tyrosine kinase activity (IEA) ?
ATP binding (IEA) ?
protein amino acid phosphorylation ?
mitosis ?
YAR018C ?
protein kinase activity ?
chromosome segregation ?
1e-38

BLAST
PF07_0023 ?
DNA replication licensing factor mcm7 homologue, putative

nucleotide binding (IEA) ?
nucleic acid binding (IEA) ?
DNA binding (IEA) ?
ATP binding (IEA) ?
nucleus (IEA) ?
DNA replication initiation ?
DNA-dependent ATPase activity ?
photosynthesis (IEA) ?
chlorophyll biosynthetic process (IEA) ?
magnesium chelatase activity (IEA) ?
ATPase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
YBR202W ?
chromatin binding ?
ATP-dependent DNA helicase activity ?
ATP binding ?
nucleus ?
pre-replicative complex ?
cytoplasm ?
pre-replicative complex assembly ?
DNA unwinding during replication ?
DNA replication initiation ?
MCM complex ?
0

BLAST

Cluster Pair #11: 11 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF10_0348 ?
hypothetical protein

receptor activity (IEA) ?
pathogenesis (IEA) ?
integral to membrane (IEA) ?
YDL058W ?
soluble fraction ?
protein complex assembly ?
ER to Golgi vesicle-mediated transport ?
0.052

BLAST
PFD1130w ?
hypothetical protein

YBR163W ?
mitochondrion ?
0.014

BLAST
PFI1475w ?
merozoite surface protein 1, precursor

pathogenesis (IEA) ?
membrane (IEA) ?
YDL058W ?
soluble fraction ?
protein complex assembly ?
ER to Golgi vesicle-mediated transport ?
4e-05

BLAST
PF14_0172 ?
hypothetical protein

metalloendopeptidase activity (IEA) ?
proteolysis (IEA) ?
pathogenesis (IEA) ?
metal ion binding (IEA) ?
YDL058W ?
soluble fraction ?
protein complex assembly ?
ER to Golgi vesicle-mediated transport ?
4e-05

BLAST
PF13_0233 ?
myosin a

motor activity ?
actin binding ?
ATP binding ?
plasma membrane ?
myosin complex ?
pellicle ?
YAL029C ?
microfilament motor activity ?
mitochondrion ?
cellular bud ?
gene conversion at mating-type locus ?
intracellular mRNA localization ?
myosin V complex ?
filamentous actin ?
endoplasmic reticulum inheritance ?
actin filament binding ?
0

BLAST
PFL1090w ?
hypothetical protein

YDL058W ?
soluble fraction ?
protein complex assembly ?
ER to Golgi vesicle-mediated transport ?
0.45

BLAST
PF13_0173 ?
hypothetical protein

YBR215W ?
G1/S-specific transcription in mitotic cell cycle ?
HIR complex ?
nucleus ?
DNA replication-independent nucleosome assembly ?
RNA elongation from RNA polymerase II promoter ?
transcription regulator activity ?
0.13

BLAST
PF11_0477 ?
CCAAT-box DNA binding protein subunit B

DNA binding ?
nucleus (IEA) ?
regulation of transcription, DNA-dependent ?
YBL021C ?
nucleus ?
regulation of carbohydrate metabolic process ?
transcription ?
transcription activator activity ?
CCAAT-binding factor complex ?
3e-25

BLAST
PF11_0278 ?
hypothetical protein

membrane ?
apicoplast ?
YDL058W ?
soluble fraction ?
protein complex assembly ?
ER to Golgi vesicle-mediated transport ?
0.001

BLAST
PFL1340c ?
hypothetical protein

YDL058W ?
soluble fraction ?
protein complex assembly ?
ER to Golgi vesicle-mediated transport ?
0.0008

BLAST
PFB0670c ?
hypothetical protein

membrane ?
YDL058W ?
soluble fraction ?
protein complex assembly ?
ER to Golgi vesicle-mediated transport ?
2e-10

BLAST

Cluster Pair #12: 4 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF11_0331 ?
t-complex protein 1, alpha subunit, putative

protein binding (IEA) ?
ATP binding ?
chaperonin-containing T-complex ?
protein folding ?
cytoskeleton organization and biogenesis ?
cellular protein metabolic process (IEA) ?
unfolded protein binding ?
YDR212W ?
cytoplasm ?
chaperonin-containing T-complex ?
cytoskeleton ?
protein folding ?
cytoskeleton organization and biogenesis ?
unfolded protein binding ?
0

BLAST
PFB0245c ?
DNA-directed RNA polymerase II 16 kDa subunit, putative

DNA-directed RNA polymerase activity ?
transcription (IEA) ?
transcription from RNA polymerase II promoter ?
YJL140W ?
mRNA catabolic process, deadenylation-dependent decay ?
telomere maintenance ?
cytoplasmic mRNA processing body ?
DNA-directed RNA polymerase activity ?
nucleus ?
DNA-directed RNA polymerase II, core complex ?
cytoplasm ?
transcription from RNA polymerase II promoter ?
mRNA export from nucleus ?
0.0003

BLAST
PFI1130c ?
DNA-directed RNA polymerase II, putative

DNA binding (IEA) ?
DNA-directed RNA polymerase activity (IEA) ?
transcription (IEA) ?
protein dimerization activity (IEA) ?
YIL021W ?
DNA-directed RNA polymerase activity ?
DNA-directed RNA polymerase II, core complex ?
transcription from RNA polymerase II promoter ?
2e-22

BLAST
PF08_0028 ?
hypothetical protein

YGL112C ?
G1-specific transcription in mitotic cell cycle ?
SAGA complex ?
transcription factor TFIID complex ?
establishment and/or maintenance of chromatin architecture ?
transcription initiation from RNA polymerase II promoter ?
protein amino acid acetylation ?
general RNA polymerase II transcription factor activity ?
chromatin modification ?
histone acetylation ?
SLIK (SAGA-like) complex ?
0.1

BLAST

Cluster Pair #13: 5 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF14_0324 ?
hypothetical protein, conserved

YOR027W ?
cytoplasm ?
protein folding ?
chaperone activator activity ?
chaperone inhibitor activity ?
Hsp70 protein binding ?
Hsp90 protein binding ?
0

BLAST
PF10_0153 ?
hsp60

protein binding (IEA) ?
ATP binding (IEA) ?
mitochondrion ?
protein folding ?
protein targeting to mitochondrion ?
response to unfolded protein ?
ATPase activity, coupled ?
cellular protein metabolic process (IEA) ?
unfolded protein binding (IEA) ?
YLR259C ?
single-stranded DNA binding ?
mitochondrion ?
protein folding ?
protein import into mitochondrial matrix ?
mitochondrial nucleoid ?
0

BLAST
PF07_0029 ?
heat shock protein 86

ATP binding (IEA) ?
protein folding (IEA) ?
response to unfolded protein ?
response to heat ?
unfolded protein binding (IEA) ?
also with YPL240C, clust.pair #13
YMR186W ?
telomere maintenance ?
cytoplasm ?
mitochondrion ?
protein folding ?
'de novo' protein folding ?
response to stress ?
protein refolding ?
ATPase activity, coupled ?
proteasome assembly ?
unfolded protein binding ?
0

BLAST
PF07_0029 ?
heat shock protein 86

ATP binding (IEA) ?
protein folding (IEA) ?
response to unfolded protein ?
response to heat ?
unfolded protein binding (IEA) ?
also with YMR186W, clust.pair #13
YPL240C ?
cytoplasm ?
'de novo' protein folding ?
response to stress ?
response to osmotic stress ?
protein refolding ?
ATPase activity, coupled ?
proteasome assembly ?
unfolded protein binding ?
0

BLAST
PFB0953w ?
hypothetical protein

membrane ?
YBR169C ?
adenyl-nucleotide exchange factor activity ?
cytoplasm ?
protein folding ?
protein refolding ?
0.059

BLAST

Cluster Pair #14: 5 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFE0975c ?
40S ribosomal subunit protein S24, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translation (IEA) ?
also with YIL069C, clust.pair #14
YER074W ?
structural constituent of ribosome ?
mitochondrion ?
translation ?
3e-33

BLAST
PFE0975c ?
40S ribosomal subunit protein S24, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translation (IEA) ?
also with YER074W, clust.pair #14
YIL069C ?
structural constituent of ribosome ?
translation ?
3e-33

BLAST
PF14_0627 ?
ribosomal protein S3, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
small ribosomal subunit (IEA) ?
YNL178W ?
structural constituent of ribosome ?
translation ?
response to DNA damage stimulus ?
nucleolar preribosome, small subunit precursor ?
0

BLAST
MAL7P1.122 ?
conserved GTP-binding protein, putative

GTP binding ?
signal transduction ?
YBR025C ?
cytoplasm ?
0

BLAST
PFE0630c ?
orotate phosphoribosyltransferase, putative

orotate phosphoribosyltransferase activity ?
nucleoside metabolic process (IEA) ?
YML106W ?
orotate phosphoribosyltransferase activity ?
nucleus ?
cytoplasm ?
'de novo' pyrimidine base biosynthetic process ?
3e-16

BLAST

Cluster Pair #15: 4 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFC0300c ?
60S ribosomal protein L7, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit (IEA) ?
transcription regulator activity (IEA) ?
YPL198W ?
structural constituent of ribosome ?
translation ?
1.00053e-42

BLAST
PFD1055w ?
ribosomal protein S19s, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome ?
translation ?
also with YOL121C, clust.pair #15
YNL302C ?
ribosomal small subunit export from nucleus ?
structural constituent of ribosome ?
rRNA processing ?
translation ?
ribosomal small subunit biogenesis and assembly ?
3e-20

BLAST
PFD1055w ?
ribosomal protein S19s, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome ?
translation ?
also with YNL302C, clust.pair #15
YOL121C ?
ribosomal small subunit export from nucleus ?
telomere maintenance ?
structural constituent of ribosome ?
rRNA processing ?
translation ?
ribosomal small subunit biogenesis and assembly ?
3e-20

BLAST
PFC0200w ?
60S Ribosomal protein L44, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
YNL162W ?
structural constituent of ribosome ?
translation ?
6e-30

BLAST

Cluster Pair #16: 4 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF07_0117 ?
eukaryotic translation initiation factor 2 alpha subunit, putative

nucleic acid binding (IEA) ?
RNA binding (IEA) ?
translation initiation factor activity ?
eukaryotic translation initiation factor 2 complex ?
translation (IEA) ?
translational initiation ?
YJR007W ?
translation initiation factor activity ?
cytoplasm ?
ribosome ?
eukaryotic translation initiation factor 2 complex ?
translational initiation ?
multi-eIF complex ?
0

BLAST
MAL13P1.344 ?
RNAse L inhibitor protein, putative

nucleotide binding (IEA) ?
iron ion binding (IEA) ?
ATP binding (IEA) ?
electron transport (IEA) ?
electron carrier activity (IEA) ?
ATPase activity (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
YDR091C ?
ribosome export from nucleus ?
iron ion binding ?
nucleus ?
cytoplasm ?
translational initiation ?
ATPase activity ?
ribosomal large subunit biogenesis and assembly ?
0

BLAST
PF14_0411 ?
small nuclear ribonuclear protein, putative

nucleus (IEA) ?
small nucleolar ribonucleoprotein complex ?
mRNA processing (IEA) ?
RNA splicing ?
ribonucleoprotein complex (IEA) ?
YER146W ?
nuclear mRNA splicing, via spliceosome ?
RNA binding ?
snRNP U6 ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
mRNA catabolic process ?
RNA splicing factor activity, transesterification mechanism ?
U4/U6 x U5 tri-snRNP complex ?
2e-08

BLAST
PFL2105c ?
hypothetical protein

YKL018W ?
telomere maintenance ?
mRNA cleavage and polyadenylation specificity factor complex ?
histone methylation ?
termination of RNA polymerase II transcription, poly(A)-coupled ?
termination of RNA polymerase II transcription, poly(A)-independent ?
mRNA 3'-end processing ?
snoRNA 3'-end processing ?
histone lysine N-methyltransferase activity (H3-K4 specific) ?
COMPASS complex ?
3e-14

BLAST

Cluster Pair #17: 3 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFL0960w ?
D-ribulose-5-phosphate 3-epimerase, putative

ribulose-phosphate 3-epimerase activity ?
carbohydrate metabolic process (IEA) ?
pentose-phosphate shunt, non-oxidative branch ?
YJL121C ?
ribulose-phosphate 3-epimerase activity ?
cytosol ?
pentose-phosphate shunt ?
0

BLAST
PF11_0198 ?
hypothetical protein, conserved

RNA binding (IEA) ?
tRNA processing (IEA) ?
tRNA methyltransferase activity (IEA) ?
YOL093W ?
nucleus ?
cytoplasm ?
tRNA (guanine) methyltransferase activity ?
tRNA methylation ?
5e-17

BLAST
PF07_0011 ?
hypothetical protein, conserved

YHR122W ?
nucleus ?
cytoplasm ?
transcription ?
1e-23

BLAST

Cluster Pair #18: 11 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
MAL13P1.209 ?
60S ribosomal subunit porotein L18, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YNL301C, clust.pair #23
YOL120C ?
structural constituent of ribosome ?
translation ?
8.00001e-42

BLAST
PF11_0065 ?
ribosomal protein S4, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
small ribosomal subunit ?
also with YHR203C, clust.pair #22
YJR145C ?
telomere maintenance ?
structural constituent of ribosome ?
cytoplasm ?
translation ?
maturation of SSU-rRNA ?
0

BLAST
PF13_0268 ?
ribosomal protein L17, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit (IEA) ?
also with YJL177W, clust.pair #22
YKL180W ?
structural constituent of ribosome ?
cytoplasm ?
translation ?
4.00001e-40

BLAST
PFC0290w ?
40S ribosomal protein S23, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
small ribosomal subunit (IEA) ?
also with YGR118W, clust.pair #22
YPR132W ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
regulation of translational fidelity ?
0

BLAST
PFF0700c ?
60S ribosomal protein L19, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YBR084C-A, clust.pair #18
YBL027W ?
structural constituent of ribosome ?
translation ?
7e-39

BLAST
PFF0700c ?
60S ribosomal protein L19, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YBL027W, clust.pair #18
YBR084C-A ?
structural constituent of ribosome ?
translation ?
7e-39

BLAST
PFE0185c ?
60S ribosomal subunit protein L31, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit ?
also with YLR406C, clust.pair #21
YDL075W ?
structural constituent of ribosome ?
translation ?
9e-21

BLAST
PFL2055w ?
40S ribosomal protein S17, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
YDR447C ?
ribosomal small subunit assembly and maintenance ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
4e-33

BLAST
PF13_0228 ?
40S ribosomal subunit protein S6, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YPL090C, clust.pair #21
YBR181C ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytoplasm ?
translation ?
0

BLAST
PFC0735w ?
40S ribosomal protein S15A, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YJL190C, clust.pair #21
YLR367W ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF14_0296 ?
ribosomal protein L14, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
apicoplast ?
also with YKL006W, clust.pair #22
YHL001W ?
RNA binding ?
structural constituent of ribosome ?
translation ?
0.006

BLAST

Cluster Pair #19: 13 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF11_0208 ?
phosphoglycerate mutase, putative

phosphoglycerate mutase activity ?
cytosol ?
glycolysis ?
intramolecular transferase activity, phosphotransferases (IEA) ?
YKL152C ?
phosphoglycerate mutase activity ?
mitochondrion ?
cytosol ?
gluconeogenesis ?
glycolysis ?
0

BLAST
PF14_0083 ?
ribosomal protein S8e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
translation ?
also with YBL072C, clust.pair #21
YER102W ?
structural constituent of ribosome ?
translation ?
0

BLAST
PFB0885w ?
40S ribosomal protein S30, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
YOR182C ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
4e-13

BLAST
PFC1020c ?
40S ribosomal protein S3A, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YML063W, clust.pair #22
YLR441C ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF14_0579 ?
ribosomal protein L27, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YDR471W, clust.pair #23
YHR010W ?
structural constituent of ribosome ?
translation ?
1e-16

BLAST
PFD0770c ?
ribosomal protein l15, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome ?
translation ?
also with YMR121C, clust.pair #23
YLR029C ?
RNA binding ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF08_0076 ?
40S ribosomal protein S16, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
YDL083C ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
9.80909e-45

BLAST
PF14_0027 ?
ribosomal S27a, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation (IEA) ?
protein modification process (IEA) ?
YLR167W ?
ribosomal small subunit assembly and maintenance ?
structural constituent of ribosome ?
cytoplasm ?
translation ?
protein ubiquitination ?
protein tag ?
ribosome biogenesis and assembly ?
1e-12

BLAST
MAL13P1.92 ?
40S ribosomal protein S15, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
small ribosomal subunit (IEA) ?
YOL040C ?
ribosomal small subunit export from nucleus ?
structural constituent of ribosome ?
translation ?
5e-36

BLAST
PF08_0039 ?
ribosomal protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
YLR061W ?
structural constituent of ribosome ?
translation ?
1e-07

BLAST
PF07_0043 ?
60S ribosomal protein L34-a, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translation (IEA) ?
also with YIL052C, clust.pair #22
YER056C-A ?
structural constituent of ribosome ?
translation ?
1e-30

BLAST
PF13_0049 ?
60S ribosomal protein L24, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YGL031C, clust.pair #19
YGR148C ?
RNA binding ?
structural constituent of ribosome ?
translation ?
3e-10

BLAST
PF13_0049 ?
60S ribosomal protein L24, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YGR148C, clust.pair #19
YGL031C ?
RNA binding ?
structural constituent of ribosome ?
translation ?
4e-10

BLAST

Cluster Pair #20: 7 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF14_0104 ?
eukaryotic translation initiation factor 2 gamma subunit, putative

GTP binding ?
eukaryotic translation initiation factor 2 complex ?
translation (IEA) ?
translational initiation ?
YER025W ?
translation initiation factor activity ?
ribosome ?
eukaryotic translation initiation factor 2 complex ?
translational initiation ?
multi-eIF complex ?
0

BLAST
PF13_0157 ?
ribose-phosphate pyrophosphokinase, putative

histidine biosynthetic process ?
tryptophan biosynthetic process ?
ribose phosphate diphosphokinase activity ?
nucleoside metabolic process ?
nucleotide biosynthetic process (IEA) ?
apicoplast ?
YKL181W ?
histidine biosynthetic process ?
tryptophan biosynthetic process ?
ribose phosphate diphosphokinase activity ?
cytoplasm ?
purine ribonucleoside salvage ?
'de novo' IMP biosynthetic process ?
'de novo' pyrimidine base biosynthetic process ?
1e-35

BLAST
PFL0310c ?
eukaryotic translation initiation factor 3 subunit 8, putative

translation initiation factor activity ?
eukaryotic translation initiation factor 3 complex ?
translational initiation (IEA) ?
regulation of translational initiation ?
YMR309C ?
translation initiation factor activity ?
cytoplasm ?
eukaryotic translation initiation factor 3 complex ?
translational initiation ?
ribosome biogenesis and assembly ?
multi-eIF complex ?
9.99995e-41

BLAST
PF10_0225 ?
orotidine-monophosphate-decarboxylase, putative

orotidine-5'-phosphate decarboxylase activity ?
'de novo' pyrimidine base biosynthetic process ?
pyrimidine nucleotide biosynthetic process (IEA) ?
YGR090W ?
nucleus ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
snoRNA binding ?
1.1

BLAST
PFF0345w ?
translation initiation factor IF-2, putative

translation initiation factor activity ?
GTP binding (IEA) ?
translation (IEA) ?
translational initiation ?
YAL035W ?
translation initiation factor activity ?
GTPase activity ?
mitochondrion ?
translational initiation ?
0

BLAST
PFE1335c ?
hypothetical protein

YGR162W ?
translation initiation factor activity ?
mitochondrion ?
ribosome ?
translational initiation ?
eukaryotic translation initiation factor 4F complex ?
ribosome biogenesis and assembly ?
0.004

BLAST
PFE1140c ?
G10 protein, putative

nucleus (IEA) ?
YCR063W ?
cellular bud site selection ?
nucleus ?
RNA splicing ?
9.94922e-44

BLAST

Cluster Pair #21: 18 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF08_0019 ?
guanine nucleotide-binding protein, putative

protein kinase C binding ?
heterotrimeric G-protein complex ?
G-protein coupled receptor protein signaling pathway ?
YMR116C ?
telomere maintenance ?
cytoplasm ?
negative regulation of translation ?
0

BLAST
PF10_0264 ?
40S ribosomal protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
small ribosomal subunit (IEA) ?
also with YGR214W, clust.pair #23
YLR048W ?
ribosomal small subunit assembly and maintenance ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF11_0313 ?
ribosomal phosphoprotein P0

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
translational elongation (IEA) ?
ribosome biogenesis and assembly (IEA) ?
YLR340W ?
ribosomal large subunit assembly and maintenance ?
structural constituent of ribosome ?
translation ?
translational elongation ?
0

BLAST
PF14_0240 ?
ribosomal protein L21e, putative

structural constituent of ribosome ?
mitochondrion ?
translation ?
also with YPL079W, clust.pair #22
YBR191W ?
structural constituent of ribosome ?
translation ?
4e-28

BLAST
PF14_0083 ?
ribosomal protein S8e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
translation ?
also with YER102W, clust.pair #19
YBL072C ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF14_0391 ?
ribosomal protein L1, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YGL135W, clust.pair #23
YPL220W ?
structural constituent of ribosome ?
translation ?
0

BLAST
PFE0350c ?
60S ribosomal subunit protein L4%2FL1, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit ?
also with YDR012W, clust.pair #21
YBR031W ?
structural constituent of ribosome ?
translation ?
0

BLAST
PFE0350c ?
60S ribosomal subunit protein L4%2FL1, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit ?
also with YBR031W, clust.pair #21
YDR012W ?
structural constituent of ribosome ?
cytoplasm ?
translation ?
0

BLAST
PF11_0272 ?
ribosomal protein S18, putative

RNA binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
small ribosomal subunit ?
YDR450W ?
telomere maintenance ?
structural constituent of ribosome ?
mitochondrion ?
translation ?
0

BLAST
PF11_0043 ?
60S acidic ribosomal protein p1, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
translational elongation (IEA) ?
large ribosomal subunit ?
YDL081C ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
translational elongation ?
2e-06

BLAST
PFE0185c ?
60S ribosomal subunit protein L31, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit ?
also with YDL075W, clust.pair #18
YLR406C ?
structural constituent of ribosome ?
translation ?
5e-21

BLAST
PFI0645w ?
EF-1B

translation elongation factor activity (IEA) ?
eukaryotic translation elongation factor 1 complex (IEA) ?
translational elongation (IEA) ?
YAL003W ?
translation elongation factor activity ?
ribosome ?
eukaryotic translation elongation factor 1 complex ?
translational elongation ?
7e-06

BLAST
PF13_0304 ?
elongation factor 1 alpha

translation elongation factor activity ?
GTP binding (IEA) ?
cytoplasm (IEA) ?
eukaryotic translation elongation factor 1 complex ?
translation (IEA) ?
translational elongation ?
also with YPR080W, clust.pair #26
YBR118W ?
translation elongation factor activity ?
ribosome ?
eukaryotic translation elongation factor 1 complex ?
tRNA export from nucleus ?
translational elongation ?
0

BLAST
PF13_0228 ?
40S ribosomal subunit protein S6, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YBR181C, clust.pair #18
YPL090C ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
translation ?
0

BLAST
PFC0735w ?
40S ribosomal protein S15A, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YLR367W, clust.pair #18
YJL190C ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
0

BLAST
PFE1005w ?
40S ribosomal subunit protein S9, putative

RNA binding (IEA) ?
structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translation (IEA) ?
small ribosomal subunit (IEA) ?
also with YPL081W, clust.pair #22
YBR189W ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
translation ?
regulation of translational fidelity ?
0

BLAST
PF14_0585 ?
ribosomal protein S28e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YLR264W, clust.pair #23
YOR167C ?
structural constituent of ribosome ?
translation ?
5e-12

BLAST
PFC0400w ?
60S Acidic ribosomal protein P2

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translational elongation ?
large ribosomal subunit ?
YDR382W ?
structural constituent of ribosome ?
translation ?
translational elongation ?
9e-11

BLAST

Cluster Pair #22: 23 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF13_0214 ?
elongation factor 1-gamma, putative

translation elongation factor activity ?
glutathione transferase activity ?
eukaryotic translation elongation factor 1 complex ?
translational elongation ?
YKL081W ?
translation elongation factor activity ?
mitochondrion ?
ribosome ?
eukaryotic translation elongation factor 1 complex ?
translational elongation ?
4e-24

BLAST
PF11_0270 ?
threonine -- tRNA ligase, putative

aminoacyl-tRNA ligase activity (IEA) ?
threonine-tRNA ligase activity ?
ATP binding ?
mitochondrion ?
translation (IEA) ?
tRNA aminoacylation for protein translation (IEA) ?
threonyl-tRNA aminoacylation ?
apicoplast ?
YIL078W ?
threonine-tRNA ligase activity ?
cytoplasm ?
mitochondrion ?
translation ?
0

BLAST
PF14_0240 ?
ribosomal protein L21e, putative

structural constituent of ribosome ?
mitochondrion ?
translation ?
also with YBR191W, clust.pair #21
YPL079W ?
structural constituent of ribosome ?
translation ?
5e-28

BLAST
PF14_0141 ?
ribosomal protein L10, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
YLR075W ?
ribosomal large subunit assembly and maintenance ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF11_0065 ?
ribosomal protein S4, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
small ribosomal subunit ?
also with YJR145C, clust.pair #18
YHR203C ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF10_0272 ?
ribosomal protein L3, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
YOR063W ?
ribosomal large subunit assembly and maintenance ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF13_0268 ?
ribosomal protein L17, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit (IEA) ?
also with YKL180W, clust.pair #18
YJL177W ?
structural constituent of ribosome ?
translation ?
3e-40

BLAST
PFC1020c ?
40S ribosomal protein S3A, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YLR441C, clust.pair #19
YML063W ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF11_0051 ?
phenylalanine -- tRNA ligase, putative

phenylalanine-tRNA ligase activity ?
ATP binding (IEA) ?
cytoplasm (IEA) ?
phenylalanyl-tRNA aminoacylation ?
phenylalanine-tRNA ligase complex ?
YLR060W ?
phenylalanine-tRNA ligase activity ?
cytoplasm ?
phenylalanyl-tRNA aminoacylation ?
phenylalanine-tRNA ligase complex ?
0

BLAST
PFC0290w ?
40S ribosomal protein S23, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
small ribosomal subunit (IEA) ?
also with YPR132W, clust.pair #18
YGR118W ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
regulation of translational fidelity ?
0

BLAST
PF13_0213 ?
60S ribosomal subunit protein L6e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YML073C, clust.pair #22
YLR448W ?
ribosomal large subunit assembly and maintenance ?
RNA binding ?
structural constituent of ribosome ?
translation ?
7e-16

BLAST
PF13_0213 ?
60S ribosomal subunit protein L6e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YLR448W, clust.pair #22
YML073C ?
ribosomal large subunit assembly and maintenance ?
RNA binding ?
structural constituent of ribosome ?
translation ?
1e-14

BLAST
PF10_0043 ?
ribosomal protein L13, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit (IEA) ?
also with YNL069C, clust.pair #23
YIL133C ?
RNA binding ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF10_0187 ?
ribosomal protein L30e, putative

structural constituent of ribosome ?
translation ?
YGL030W ?
structural constituent of ribosome ?
cytoplasm ?
rRNA processing ?
translation ?
negative regulation of translation ?
negative regulation of nuclear mRNA splicing, via spliceosome ?
2e-26

BLAST
PF13_0129 ?
ribosomal protein L6 homologue, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit ?
also with YNL067W, clust.pair #22
YGL147C ?
structural constituent of ribosome ?
translation ?
9.99995e-41

BLAST
PF13_0129 ?
ribosomal protein L6 homologue, putative

RNA binding ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit ?
also with YGL147C, clust.pair #22
YNL067W ?
structural constituent of ribosome ?
translation ?
9.99995e-41

BLAST
PF10_0103 ?
eukaryotic translation initiation factor 2, beta, putative

RNA binding ?
translation initiation factor activity ?
eukaryotic translation initiation factor 2 complex ?
translational initiation ?
YPL237W ?
translation initiation factor activity ?
ribosome ?
eukaryotic translation initiation factor 2 complex ?
translational initiation ?
multi-eIF complex ?
6e-32

BLAST
PF14_0448 ?
ribosomal protein S2, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
small ribosomal subunit (IEA) ?
YGL123W ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
translation ?
regulation of translational fidelity ?
0

BLAST
PF13_0014 ?
40S ribosomal protein S7 homologue, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
YNL096C ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
translation ?
5e-31

BLAST
PFE1005w ?
40S ribosomal subunit protein S9, putative

RNA binding (IEA) ?
structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translation (IEA) ?
small ribosomal subunit (IEA) ?
also with YBR189W, clust.pair #21
YPL081W ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
cytoplasm ?
translation ?
regulation of translational fidelity ?
0

BLAST
PF14_0296 ?
ribosomal protein L14, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
apicoplast ?
also with YHL001W, clust.pair #18
YKL006W ?
RNA binding ?
structural constituent of ribosome ?
translation ?
0.004

BLAST
PF07_0043 ?
60S ribosomal protein L34-a, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translation (IEA) ?
also with YER056C-A, clust.pair #19
YIL052C ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
1e-30

BLAST
PF11_0312 ?
ribosomal protein L38e

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
YLR325C ?
structural constituent of ribosome ?
translation ?
0.11

BLAST

Cluster Pair #23: 30 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF14_0486 ?
elongation factor 2

translation elongation factor activity ?
GTP binding ?
translation (IEA) ?
translational elongation ?
also with YOR133W, clust.pair #23
YDR385W ?
translation elongation factor activity ?
ribosome ?
translational elongation ?
0

BLAST
PF14_0486 ?
elongation factor 2

translation elongation factor activity ?
GTP binding ?
translation (IEA) ?
translational elongation ?
also with YDR385W, clust.pair #23
YOR133W ?
translation elongation factor activity ?
ribosome ?
translational elongation ?
0

BLAST
PFE0660c ?
uridine phosphorylase, putative

catalytic activity (IEA) ?
uridine phosphorylase activity ?
nucleoside metabolic process (IEA) ?
also with YNL209W, clust.pair #23
YDL229W ?
soluble fraction ?
polysome ?
translation ?
regulation of translational fidelity ?
ATPase activity ?
unfolded protein binding ?
'de novo' cotranslational protein folding ?
1.3

BLAST
PFE0660c ?
uridine phosphorylase, putative

catalytic activity (IEA) ?
uridine phosphorylase activity ?
nucleoside metabolic process (IEA) ?
also with YDL229W, clust.pair #23
YNL209W ?
cytoplasm ?
polysome ?
translation ?
regulation of translational fidelity ?
ATPase activity ?
unfolded protein binding ?
'de novo' cotranslational protein folding ?
1.3

BLAST
PF10_0264 ?
40S ribosomal protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
small ribosomal subunit (IEA) ?
also with YLR048W, clust.pair #21
YGR214W ?
ribosomal small subunit assembly and maintenance ?
structural constituent of ribosome ?
translation ?
0

BLAST
MAL13P1.209 ?
60S ribosomal subunit porotein L18, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YOL120C, clust.pair #18
YNL301C ?
structural constituent of ribosome ?
translation ?
8.00001e-42

BLAST
PF13_0143 ?
phosphoribosylpyrophosphate synthetase

ribose phosphate diphosphokinase activity ?
pentose-phosphate shunt ?
purine ribonucleoside salvage ?
nucleoside metabolic process (IEA) ?
nucleotide biosynthetic process (IEA) ?
YBL068W ?
histidine biosynthetic process ?
tryptophan biosynthetic process ?
ribose phosphate diphosphokinase activity ?
cytoplasm ?
purine ribonucleoside salvage ?
'de novo' IMP biosynthetic process ?
'de novo' pyrimidine base biosynthetic process ?
ribosome biogenesis and assembly ?
0

BLAST
PFL0900c ?
arginyl-tRNA synthetase, putative

arginine-tRNA ligase activity ?
ATP binding (IEA) ?
arginyl-tRNA aminoacylation ?
apicoplast ?
YDR341C ?
arginine-tRNA ligase activity ?
cytoplasm ?
mitochondrion ?
translation ?
3.9937e-43

BLAST
PFL1745c ?
clustered-asparagine-rich protein

nucleic acid binding (IEA) ?
RNA binding ?
YER165W ?
nucleus ?
cytoplasm ?
ribosome ?
regulation of translational initiation ?
poly(A) binding ?
4e-08

BLAST
PF14_0391 ?
ribosomal protein L1, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YPL220W, clust.pair #21
YGL135W ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF14_0230 ?
Ribosomal protein family L5, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
5S rRNA binding (IEA) ?
YPL131W ?
ribosomal large subunit assembly and maintenance ?
RNA binding ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF07_0088 ?
40S ribosomal protein S5, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
small ribosomal subunit (IEA) ?
YJR123W ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF14_0579 ?
ribosomal protein L27, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YHR010W, clust.pair #19
YDR471W ?
structural constituent of ribosome ?
translation ?
5e-16

BLAST
PFD0770c ?
ribosomal protein l15, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome ?
translation ?
also with YLR029C, clust.pair #19
YMR121C ?
RNA binding ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF13_0179 ?
isoleucine--tRNA ligase, putative

aminoacyl-tRNA ligase activity (IEA) ?
isoleucine-tRNA ligase activity (IEA) ?
ATP binding (IEA) ?
tRNA aminoacylation for protein translation (IEA) ?
isoleucyl-tRNA aminoacylation (IEA) ?
YBL076C ?
isoleucine-tRNA ligase activity ?
cytosol ?
translation ?
0

BLAST
PF14_0028 ?
hypothetical protein, conserved

nucleic acid binding (IEA) ?
RNA binding (IEA) ?
RNA processing (IEA) ?
ATP biosynthetic process (IEA) ?
ATP synthesis coupled proton transport (IEA) ?
proton-transporting two-sector ATPase complex (IEA) ?
hydrogen ion transporting ATP synthase activity, rotational mechanism (IEA) ?
hydrogen ion transporting ATPase activity, rotational mechanism (IEA) ?
YER165W ?
nucleus ?
cytoplasm ?
ribosome ?
regulation of translational initiation ?
poly(A) binding ?
6e-06

BLAST
PF13_0354 ?
alanine--tRNA ligase, putative

alanine-tRNA ligase activity ?
ATP binding (IEA) ?
alanyl-tRNA aminoacylation ?
apicoplast ?
YOR335C ?
alanine-tRNA ligase activity ?
cytoplasm ?
mitochondrion ?
alanyl-tRNA aminoacylation ?
0

BLAST
PFB0445c ?
helicase, putative

nucleic acid binding (IEA) ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
ATP-dependent helicase activity (IEA) ?
YDL084W ?
transcription export complex ?
U2-type nuclear mRNA branch site recognition ?
nuclear mRNA splicing, via spliceosome ?
chromosome, telomeric region ?
RNA binding ?
ATP-dependent RNA helicase activity ?
protein binding ?
nucleus ?
spliceosome ?
chromatin silencing at telomere ?
mRNA export from nucleus ?
RNA splicing factor activity, transesterification mechanism ?
0

BLAST
PF08_0075 ?
60S ribosomal protein L13, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
YDL082W ?
structural constituent of ribosome ?
translation ?
3e-18

BLAST
PF11_0200 ?
U2 snRNP auxiliary factor, small subunit, putative

nuclear mRNA splicing, via spliceosome ?
nucleic acid binding (IEA) ?
RNA binding ?
nucleus (IEA) ?
snRNP U2 ?
YER165W ?
nucleus ?
cytoplasm ?
ribosome ?
regulation of translational initiation ?
poly(A) binding ?
0.024

BLAST
PFL0670c ?
Bi-functional aminoacyl-tRNA synthetase, putative

aminoacyl-tRNA ligase activity (IEA) ?
glutamate-tRNA ligase activity ?
proline-tRNA ligase activity ?
ATP binding (IEA) ?
cytoplasm (IEA) ?
translation (IEA) ?
tRNA aminoacylation for protein translation ?
prolyl-tRNA aminoacylation (IEA) ?
YHR020W ?
proline-tRNA ligase activity ?
ribosome ?
tRNA aminoacylation for protein translation ?
0

BLAST
PFD1070w ?
eukaryotic initiation factor, putative

nucleic acid binding (IEA) ?
translation initiation factor activity ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
regulation of translational initiation ?
ATP-dependent helicase activity (IEA) ?
eukaryotic translation initiation factor 4F complex ?
also with YKR059W, clust.pair #23
YJL138C ?
RNA helicase activity ?
translation initiation factor activity ?
cytoplasm ?
ribosome ?
translational initiation ?
regulation of translational initiation ?
eukaryotic translation initiation factor 4F complex ?
0

BLAST
PFD1070w ?
eukaryotic initiation factor, putative

nucleic acid binding (IEA) ?
translation initiation factor activity ?
ATP-dependent RNA helicase activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
regulation of translational initiation ?
ATP-dependent helicase activity (IEA) ?
eukaryotic translation initiation factor 4F complex ?
also with YJL138C, clust.pair #23
YKR059W ?
telomere maintenance ?
translation initiation factor activity ?
ATP-dependent RNA helicase activity ?
ribosome ?
translational initiation ?
eukaryotic translation initiation factor 4F complex ?
0

BLAST
PF10_0043 ?
ribosomal protein L13, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit (IEA) ?
also with YIL133C, clust.pair #22
YNL069C ?
RNA binding ?
structural constituent of ribosome ?
translation ?
0

BLAST
PFI0190w ?
ribosomal protein L32, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translation (IEA) ?
YBL092W ?
structural constituent of ribosome ?
translation ?
6e-22

BLAST
PF14_0125 ?
deoxyhypusine synthase

translation ?
peptidyl-lysine modification to hypusine ?
membrane ?
spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase ?
YHR068W ?
cytoplasm ?
peptidyl-lysine modification to hypusine ?
transferase activity, transferring alkyl or aryl (other than methyl) groups ?
9.80909e-45

BLAST
PF14_0231 ?
ribosomal protein L7a, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
ribonucleoprotein complex (IEA) ?
ribosome biogenesis and assembly (IEA) ?
also with YLL045C, clust.pair #23
YHL033C ?
structural constituent of ribosome ?
translation ?
2.00386e-43

BLAST
PF14_0231 ?
ribosomal protein L7a, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
ribonucleoprotein complex (IEA) ?
ribosome biogenesis and assembly (IEA) ?
also with YHL033C, clust.pair #23
YLL045C ?
structural constituent of ribosome ?
translation ?
2.99878e-43

BLAST
PF11_0250 ?
high mobility group-like protein NHP2, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
nucleus ?
ribosome (IEA) ?
translation (IEA) ?
ribonucleoprotein complex (IEA) ?
ribosome biogenesis and assembly (IEA) ?
YEL026W ?
nuclear mRNA splicing, via spliceosome ?
RNA binding ?
nucleolus ?
small nucleolar ribonucleoprotein complex ?
maturation of SSU-rRNA ?
RNA splicing factor activity, transesterification mechanism ?
ribosome biogenesis and assembly ?
U4/U6 x U5 tri-snRNP complex ?
3e-39

BLAST
PF14_0585 ?
ribosomal protein S28e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YOR167C, clust.pair #21
YLR264W ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
5e-12

BLAST

Cluster Pair #24: 7 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF13_0224 ?
60S ribosomal subunit protein L18, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YMR242C, clust.pair #27
YOR312C ?
structural constituent of ribosome ?
translation ?
ribosome biogenesis and assembly ?
4e-34

BLAST
PF11_0454 ?
Ribosomal protein, 40S subunit, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YJL136C, clust.pair #26
YKR057W ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
4e-17

BLAST
PFC0775w ?
40S ribosomal protein S11, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YDR025W, clust.pair #24
YBR048W ?
ribosomal small subunit assembly and maintenance ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
regulation of translational fidelity ?
0

BLAST
PFC0775w ?
40S ribosomal protein S11, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YBR048W, clust.pair #24
YDR025W ?
ribosomal small subunit assembly and maintenance ?
structural constituent of ribosome ?
translation ?
regulation of translational fidelity ?
0

BLAST
PF11_0438 ?
Ribosomal protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit ?
also with YPL143W, clust.pair #24
YOR234C ?
structural constituent of ribosome ?
translation ?
1e-30

BLAST
PF11_0438 ?
Ribosomal protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit ?
also with YOR234C, clust.pair #24
YPL143W ?
structural constituent of ribosome ?
translation ?
1e-30

BLAST
PF13_0171 ?
60S ribosomal protein L23, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translation (IEA) ?
also with YER117W, clust.pair #27
YBL087C ?
structural constituent of ribosome ?
translation ?
0

BLAST

Cluster Pair #25: 4 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFB0830w ?
Ribosomal protein S26e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
also with YGL189C, clust.pair #25
YER131W ?
structural constituent of ribosome ?
translation ?
2e-26

BLAST
PFB0830w ?
Ribosomal protein S26e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
also with YER131W, clust.pair #25
YGL189C ?
structural constituent of ribosome ?
translation ?
2e-26

BLAST
PF07_0080 ?
40S ribosomal protein S10, putative

structural constituent of ribosome ?
translation ?
YOR293W ?
structural constituent of ribosome ?
translation ?
2e-20

BLAST
PFC0535w ?
60S ribosomal protein L26, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit (IEA) ?
also with YGR034W, clust.pair #26
YLR344W ?
RNA binding ?
structural constituent of ribosome ?
translation ?
1e-28

BLAST

Cluster Pair #26: 8 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFE0845c ?
60S ribosomal subunit protein L8, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit ?
also with YIL018W, clust.pair #27
YFR031C-A ?
structural constituent of ribosome ?
translation ?
0

BLAST
PF13_0305 ?
elongation factor 1 alpha

translation elongation factor activity ?
GTP binding (IEA) ?
cytoplasm (IEA) ?
eukaryotic translation elongation factor 1 complex ?
translation (IEA) ?
translational elongation ?
YPR080W ?
translation elongation factor activity ?
ribosome ?
eukaryotic translation elongation factor 1 complex ?
tRNA export from nucleus ?
translational elongation ?
0

BLAST
PF13_0304 ?
elongation factor 1 alpha

translation elongation factor activity ?
GTP binding (IEA) ?
cytoplasm (IEA) ?
eukaryotic translation elongation factor 1 complex ?
translation (IEA) ?
translational elongation ?
also with YBR118W, clust.pair #21
YPR080W ?
translation elongation factor activity ?
ribosome ?
eukaryotic translation elongation factor 1 complex ?
tRNA export from nucleus ?
translational elongation ?
0

BLAST
PF11_0454 ?
Ribosomal protein, 40S subunit, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YKR057W, clust.pair #24
YJL136C ?
structural constituent of ribosome ?
translation ?
6e-17

BLAST
PF13_0045 ?
40S ribosomal protein S27, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YKL156W, clust.pair #26
YHR021C ?
telomere maintenance ?
structural constituent of ribosome ?
translation ?
5e-27

BLAST
PF13_0045 ?
40S ribosomal protein S27, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YHR021C, clust.pair #26
YKL156W ?
structural constituent of ribosome ?
cytoplasm ?
translation ?
5e-27

BLAST
PF10_0038 ?
ribosomal protein S20e, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
small ribosomal subunit (IEA) ?
YHL015W ?
structural constituent of ribosome ?
translation ?
3e-25

BLAST
PFC0535w ?
60S ribosomal protein L26, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit (IEA) ?
also with YLR344W, clust.pair #25
YGR034W ?
RNA binding ?
structural constituent of ribosome ?
translation ?
2e-28

BLAST

Cluster Pair #27: 7 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFE0845c ?
60S ribosomal subunit protein L8, putative

nucleic acid binding (IEA) ?
structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
large ribosomal subunit ?
also with YFR031C-A, clust.pair #26
YIL018W ?
structural constituent of ribosome ?
translation ?
response to drug ?
0

BLAST
PF14_0655 ?
RNA helicase-1, putative

RNA cap binding ?
nucleic acid binding (IEA) ?
mRNA binding ?
translation initiation factor activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
regulation of translational initiation ?
ATP-dependent helicase activity ?
eukaryotic translation initiation factor 4F complex ?
also with YKR059W, clust.pair #27
YJL138C ?
RNA helicase activity ?
translation initiation factor activity ?
cytoplasm ?
ribosome ?
translational initiation ?
regulation of translational initiation ?
eukaryotic translation initiation factor 4F complex ?
0

BLAST
PF14_0655 ?
RNA helicase-1, putative

RNA cap binding ?
nucleic acid binding (IEA) ?
mRNA binding ?
translation initiation factor activity ?
helicase activity (IEA) ?
ATP binding (IEA) ?
regulation of translational initiation ?
ATP-dependent helicase activity ?
eukaryotic translation initiation factor 4F complex ?
also with YJL138C, clust.pair #27
YKR059W ?
telomere maintenance ?
translation initiation factor activity ?
ATP-dependent RNA helicase activity ?
ribosome ?
translational initiation ?
eukaryotic translation initiation factor 4F complex ?
0

BLAST
PF13_0224 ?
60S ribosomal subunit protein L18, putative

structural constituent of ribosome ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
also with YOR312C, clust.pair #24
YMR242C ?
structural constituent of ribosome ?
translation ?
4e-34

BLAST
PFE0810c ?
40S ribosomal subunit protein S14, putative

RNA binding ?
structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translation ?
YJL191W ?
ribosomal small subunit assembly and maintenance ?
RNA binding ?
structural constituent of ribosome ?
small nucleolar ribonucleoprotein complex ?
translation ?
maturation of SSU-rRNA ?
5.60519e-45

BLAST
PFB0455w ?
ribosomal L37ae protein, putative

structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
YPR043W ?
structural constituent of ribosome ?
translation ?
9e-26

BLAST
PF13_0171 ?
60S ribosomal protein L23, putative

structural constituent of ribosome (IEA) ?
intracellular (IEA) ?
ribosome (IEA) ?
translation (IEA) ?
also with YBL087C, clust.pair #24
YER117W ?
structural constituent of ribosome ?
translation ?
response to drug ?
0

BLAST

Cluster Pair #28: 6 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF10_0155 ?
enolase

phosphopyruvate hydratase complex ?
phosphopyruvate hydratase activity ?
gluconeogenesis ?
glycolysis ?
YHR174W ?
phosphopyruvate hydratase complex ?
phosphopyruvate hydratase activity ?
soluble fraction ?
gluconeogenesis ?
glycolysis ?
0

BLAST
PF14_0378 ?
triose-phosphate isomerase

triose-phosphate isomerase activity ?
gluconeogenesis ?
glycolysis ?
pentose-phosphate shunt ?
fatty acid biosynthetic process ?
metabolic process (IEA) ?
YDR050C ?
triose-phosphate isomerase activity ?
cytoplasm ?
glycolysis ?
0

BLAST
PFL0210c ?
eukaryotic initiation factor 5a, putative

nucleic acid binding (IEA) ?
translation initiation factor activity ?
translational initiation ?
YEL034W ?
translation initiation factor activity ?
protein binding ?
cytoplasm ?
mitochondrion ?
ribosome ?
translational initiation ?
0

BLAST
PF14_0023 ?
hypothetical protein, conserved

membrane ?
YDR380W ?
pyruvate decarboxylase activity ?
cytoplasm ?
leucine catabolic process ?
L-phenylalanine catabolic process ?
carboxy-lyase activity ?
phenylpyruvate decarboxylase activity ?
1.7

BLAST
PF14_0520 ?
6-phosphogluconate dehydrogenase, decarboxylating, putative

phosphogluconate dehydrogenase (decarboxylating) activity ?
pentose-phosphate shunt ?
YHR183W ?
phosphogluconate dehydrogenase (decarboxylating) activity ?
cytoplasm ?
mitochondrion ?
response to oxidative stress ?
pentose-phosphate shunt, oxidative branch ?
0

BLAST
PFL0705c ?
adrenodoxin-type ferredoxin, putative

iron ion binding (IEA) ?
mitochondrion ?
electron transport ?
electron carrier activity ?
membrane ?
YPL252C ?
mitochondrial matrix ?
heme a biosynthetic process ?
oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor ?
2e-33

BLAST

Cluster Pair #29: 6 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFD0305c ?
vacuolar ATP synthase subunit b

ATP binding (IEA) ?
cytoplasm (IEA) ?
ATP biosynthetic process (IEA) ?
vacuolar acidification ?
hydrogen-exporting ATPase activity, phosphorylative mechanism (IEA) ?
ATP synthesis coupled proton transport (IEA) ?
energy coupled proton transport, against electrochemical gradient (IEA) ?
proton-transporting two-sector ATPase complex (IEA) ?
hydrogen ion transporting ATP synthase activity, rotational mechanism (IEA) ?
hydrogen ion transporting ATPase activity, rotational mechanism ?
YBR127C ?
vacuolar proton-transporting V-type ATPase, V1 domain ?
cytoplasm ?
cellular calcium ion homeostasis ?
vacuolar acidification ?
hydrogen ion transporting ATPase activity, rotational mechanism ?
0

BLAST
PF10_0086 ?
adenylate kinase, putative

adenylate kinase activity ?
ATP binding (IEA) ?
mitochondrion ?
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (IEA) ?
phosphotransferase activity, phosphate group as acceptor (IEA) ?
nucleotide kinase activity (IEA) ?
YDR226W ?
adenylate kinase activity ?
cytoplasm ?
mitochondrion ?
mitochondrial intermembrane space ?
ADP biosynthetic process ?
nucleotide metabolic process ?
0

BLAST
PFE0285c ?
ubiquitin-like protein, putative

protein modification process (IEA) ?
ubiquitin cycle ?
modification-dependent protein catabolic process ?
protein ubiquitination during ubiquitin-dependent protein catabolic process ?
YDR510W ?
nucleus ?
septin ring ?
protein sumoylation ?
protein tag ?
1e-18

BLAST
MAL13P1.185 ?
CDK-related protein kinase 6

YLR113W ?
MAP kinase activity ?
nucleus ?
cytoplasm ?
protein amino acid phosphorylation ?
hyperosmotic response ?
osmosensory signaling pathway ?
positive regulation of transcription from RNA polymerase II promoter ?
negative regulation of transcription from RNA polymerase II promoter by pheromones ?
response to arsenic ?
6.02558e-44

BLAST
PFA0300c ?
vacuolar ATP synthase, putative

ATP binding (IEA) ?
mitochondrial proton-transporting ATP synthase complex ?
ATP synthesis coupled proton transport ?
proton-transporting two-sector ATPase complex (IEA) ?
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances (IEA) ?
hydrogen ion transporting ATPase activity, rotational mechanism ?
YKL080W ?
vacuolar proton-transporting V-type ATPase, V1 domain ?
membrane of vacuole with cell cycle-correlated morphology ?
vacuolar acidification ?
hydrogen ion transporting ATPase activity, rotational mechanism ?
9e-19

BLAST
PF11_0203 ?
hypothetical protein

nucleotide binding (IEA) ?
metalloendopeptidase activity (IEA) ?
ATP binding (IEA) ?
proteolysis (IEA) ?
zinc ion binding (IEA) ?
membrane ?
integral to membrane (IEA) ?
nucleoside-triphosphatase activity (IEA) ?
protein catabolic process (IEA) ?
YMR089C ?
cytoplasm ?
mitochondrion ?
mitochondrial inner membrane ?
m-AAA complex ?
translation ?
protein complex assembly ?
signal peptide processing ?
proteolysis ?
metallopeptidase activity ?
ATPase activity ?
protein import into mitochondrial intermembrane space ?
0

BLAST

Cluster Pair #30: 7 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PF13_0164 ?
hypothetical protein, conserved

YDR255C ?
cytosol ?
negative regulation of gluconeogenesis ?
0.004

BLAST
PF10_0186 ?
hypothetical protein

nucleic acid binding (IEA) ?
metalloendopeptidase activity (IEA) ?
proteolysis (IEA) ?
pathogenesis (IEA) ?
apicoplast ?
metal ion binding (IEA) ?
YMR173W ?
GTPase activity ?
cytoplasm ?
DNA repair ?
ATPase activity ?
5e-05

BLAST
MAL7P1.155 ?
hypothetical protein

ubiquitin ligase complex (IEA) ?
ubiquitin-protein ligase activity (IEA) ?
zinc ion binding (IEA) ?
protein ubiquitination (IEA) ?
YDR255C ?
cytosol ?
negative regulation of gluconeogenesis ?
2e-08

BLAST
PF10_0311 ?
hypothetical protein, conserved

YFR003C ?
protein phosphatase inhibitor activity ?
nucleus ?
glycogen metabolic process ?
protein amino acid dephosphorylation ?
2e-07

BLAST
PFI1680w ?
hypothetical protein

YDL091C ?
cytoplasm ?
3e-06

BLAST
PFF1280w ?
hypothetical protein

YMR173W ?
GTPase activity ?
cytoplasm ?
DNA repair ?
ATPase activity ?
4e-08

BLAST
PFF1275c ?
3-oxoacyl-%28acyl-carrier-protein%29 synthase i%2Fii

catalytic activity (IEA) ?
fatty-acid synthase activity ?
3-oxoacyl-[acyl-carrier-protein] synthase activity ?
fatty acid biosynthetic process (IEA) ?
apicoplast ?
YER061C ?
fatty-acid synthase activity ?
mitochondrion ?
fatty acid biosynthetic process ?
0

BLAST

Cluster Pair #31: 5 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFL1655c ?
hypothetical protein

DNA binding (IEA) ?
DNA-directed DNA polymerase activity (IEA) ?
nucleus (IEA) ?
DNA replication (IEA) ?
YPR175W ?
nucleus ?
replication fork ?
cytoplasm ?
leading strand elongation ?
lagging strand elongation ?
nucleotide-excision repair ?
mismatch repair ?
epsilon DNA polymerase complex ?
1e-09

BLAST
PFF0520w ?
calcium-dependent protein kinase

protein kinase activity (IEA) ?
protein serine/threonine kinase activity (IEA) ?
protein-tyrosine kinase activity (IEA) ?
calcium ion binding (IEA) ?
calmodulin binding (IEA) ?
ATP binding (IEA) ?
phosphorylase kinase complex (IEA) ?
glycogen biosynthetic process (IEA) ?
protein amino acid phosphorylation ?
also with YDL101C, clust.pair #31
YPL153C ?
DNA replication origin binding ?
protein serine/threonine/tyrosine kinase activity ?
nucleus ?
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process ?
DNA replication initiation ?
DNA repair ?
deoxyribonucleoside triphosphate biosynthetic process ?
0

BLAST
PFF0520w ?
calcium-dependent protein kinase

protein kinase activity (IEA) ?
protein serine/threonine kinase activity (IEA) ?
protein-tyrosine kinase activity (IEA) ?
calcium ion binding (IEA) ?
calmodulin binding (IEA) ?
ATP binding (IEA) ?
phosphorylase kinase complex (IEA) ?
glycogen biosynthetic process (IEA) ?
protein amino acid phosphorylation ?
also with YPL153C, clust.pair #31
YDL101C ?
cell cycle checkpoint ?
DNA damage checkpoint ?
telomere maintenance ?
protein kinase activity ?
nucleus ?
protein amino acid phosphorylation ?
0

BLAST
PF14_0602 ?
DNA polymerase alpha subunit, putative

DNA binding (IEA) ?
DNA-directed DNA polymerase activity (IEA) ?
nucleus (IEA) ?
alpha DNA polymerase:primase complex ?
DNA replication (IEA) ?
DNA replication, synthesis of RNA primer ?
YBL035C ?
nucleus ?
nuclear envelope ?
alpha DNA polymerase:primase complex ?
DNA replication initiation ?
lagging strand elongation ?
telomere capping ?
2e-16

BLAST
PFD0830w ?
bifunctional dihydrofolate reductase-thymidylate synthase

dihydrofolate reductase activity ?
thymidylate synthase activity ?
dTMP biosynthetic process ?
glycine biosynthetic process ?
nucleotide biosynthetic process ?
YOR074C ?
thymidylate synthase activity ?
nucleus ?
dTMP biosynthetic process ?
DNA-dependent DNA replication ?
0

BLAST

Cluster Pair #32: 13 gene pairs.

P. falciparumS. cerevisiaeBlast evalue
PFL2115c ?
glucose inhibited division protein A homologue, putative

membrane ?
apicoplast ?
YGL236C ?
mitochondrion ?
tRNA modification ?
translation ?
response to drug ?
0

BLAST
PFF0115c ?
elongation factor G, putative

translation elongation factor activity ?
GTP binding (IEA) ?
translation (IEA) ?
translational elongation ?
apicoplast ?
YLR069C ?
translation elongation factor activity ?
mitochondrion ?
translational elongation ?
0

BLAST
PF07_0062 ?
GTP-binding translation elongation factor tu family protein, putative

translation elongation factor activity ?
GTP binding ?
translation (IEA) ?
translational elongation ?
YLR069C ?
translation elongation factor activity ?
mitochondrion ?
translational elongation ?
5e-21

BLAST
PFI1625c ?
organelle processing peptidase, putative

YLR163C ?
mitochondrial processing peptidase activity ?
mitochondrion ?
mitochondrial protein processing during import ?
mitochondrial processing peptidase complex ?
0

BLAST
PFL1590c ?
elongation factor g, putative

translation elongation factor activity ?
GTP binding ?
mitochondrion ?
translation (IEA) ?
translational elongation ?
YLR069C ?
translation elongation factor activity ?
mitochondrion ?
translational elongation ?
0

BLAST
PF08_0071 ?
Fe-superoxide dismutase

superoxide dismutase activity (IEA) ?
superoxide metabolic process ?
response to oxidative stress ?
metal ion binding (IEA) ?
YHR008C ?
replicative cell aging ?
age-dependent response to reactive oxygen species during chronological cell aging ?
age-dependent response to oxidative stress during chronological cell aging ?
mitochondrion ?
mitochondrial matrix ?
oxygen and reactive oxygen species metabolic process ?
6e-30

BLAST
PFF0155w ?
bcs1-like protein, putative

nucleotide binding (IEA) ?
ATP binding (IEA) ?
mitochondrial inner membrane ?
protein complex assembly ?
ATPase activity ?
nucleoside-triphosphatase activity (IEA) ?
YDR375C ?
mitochondrion ?
mitochondrial inner membrane ?
aerobic respiration ?
ATPase activity ?
chaperone-mediated protein complex assembly ?
0

BLAST
PFI0570w ?
GTP-binding protein, putative

GTP binding (IEA) ?
translation (IEA) ?
small GTPase mediated signal transduction (IEA) ?
apicoplast ?
YLR289W ?
GTPase activity ?
mitochondrion ?
0

BLAST
MAL8P1.14 ?
hypothetical protein

integral to membrane (IEA) ?
protein insertion into membrane (IEA) ?
YER154W ?
mitochondrion ?
mitochondrial inner membrane ?
protein transporter activity ?
protein import into mitochondrial inner membrane ?
5e-05

BLAST
PF14_0451 ?
mitochondrial ribosomal protein S14 precursor, putative

structural constituent of ribosome ?
mitochondrial small ribosomal subunit ?
translation ?
YPR166C ?
structural constituent of ribosome ?
mitochondrion ?
mitochondrial small ribosomal subunit ?
translation ?
5e-06

BLAST
PF14_0289 ?
ribosomal protein L17, putative

organellar large ribosomal subunit ?
structural constituent of ribosome ?
intracellular (IEA) ?
mitochondrion ?
ribosome (IEA) ?
translation ?
YJL063C ?
mitochondrial genome maintenance ?
structural constituent of ribosome ?
mitochondrion ?
mitochondrial large ribosomal subunit ?
translation ?
4e-06

BLAST
PF10_0252 ?
hypothetical protein

copper ion binding (IEA) ?
mitochondrial intermembrane space (IEA) ?
copper ion transport (IEA) ?
copper chaperone activity (IEA) ?
YLL009C ?
mitochondrion ?
mitochondrial intermembrane space ?
cytosol ?
thioredoxin peroxidase activity ?
respiratory chain complex IV assembly ?
intracellular copper ion transport ?
copper chaperone activity ?
3e-07

BLAST
PFL0490c ?
hypothetical protein, conserved

YNL315C ?
mitochondrion ?
mitochondrial matrix ?
protein complex assembly ?
unfolded protein binding ?
0.003

BLAST