Clinic of Anaesthesiology and Intensive Care, University of Tartu, Puusepa, Tartu 51014, Estonia
Department of Anaesthesiology and Intensive Care, East Tallinn Central Hospital, Ravi, Tallinn 10138, Estonia
Clinic of Anaesthesiology and Intensive Care, Tartu University Hospital, Puusepa, Tartu 51014, Estonia
Klinik für Anästhesiologie und Intensivmedizin, DRK Kliniken Berlin Köpenick, Salvador-Allende-Straße, Berlin 12559, Germany
Following the publication of our article
Admission and outcome parameters of study patients
IAH
FI
Admission parameters
Total
Absent
Present
Absent
Present
Number of patients [%]
264 [100.0]
192 [72.3]
72 [27.3]
110 [41.7]
154 [58.3]
Male sex (
166 [62.9]
117 [60.9]
49 [68.1]
0.178
60 [54.5]
106 [68.8]
0.013
Age (years)
53.8 ± 20.0
52.3 ± 21.0
57.8 ± 16.8
0.047
48.6 ± 21.0
57.5 ± 18.5
< 0.001
Diabetes (
35 [13.3]
26 [13.5]
9 [12.5]
0.502
11 [10.0]
24 [15.6]
0.128
Readmission (
8 [3.0]
6 [3.1]
2 [2.8]
0.622
2 [1.8]
6 [3.9]
0.287
Sedation (
243 [92.0]
174 [90.6]
69 [95.8]
0.125
98 [89.1]
145 [94.2]
0.103
Vasoactive/inotrope (
200 [75.8]
136 [70.8]
64 [88.9]
0.001
67 [60.9]
133 [86.4]
< 0.001
Surgical profile (
175 [66.3]
122 [63.5]
53 [73.7]
0.080
67 [60.9]
108 [70.1]
0.077
Laparatomy (
60 [23.3]
21 [15.6]
31 [43.7]
< 0.001
9 [8.4]
51 [34.0]
< 0.001
Enteral feeding (
49 [18.6]
42 [21.9]
7 [9.7]
0.015
25 [22.7]
24 [15.6]
0.095
APACHE II score (points)
14.2 ± 7.7
13.5 ± 7.6
16.0 ± 7.7
0.016
11.8 ± 7.3
15.8 ± 7.6
< 0.001
BMI (kg/m2)
27.6 ± 13.1
25.4 ± 4.6
33.1 ± 22.2
< 0.001
25.8 ± 5.6
28.9 ± 16.4
0.080
SOFA score (points)
7.0 ± 4.2
6.3 ± 4.2
8.9 ± 3.6
< 0.001
5.3 ± 4.2
8.2 ± 3.8
< 0.001
Fluid gain in first 24 hours (l)
2.4 ± 3.6
2.0 ± 2.4
3.6 ± 5.5
0.001
1.7 ± 2.4
2.9 ± 4.2
0.007
MAP (mmHg)
81.5 ± 15.9
82.1 ± 16.4
80.5 ± 15.0
0.512
82.1 ± 15.8
81.3 ± 16.1
0.758
IAP (mmHg)
8.5 ± 4.7
6.5 ± 3.8
12.1 ± 4.0
< 0.001
6.3 ± 4.0
9.5 ± 4.6
< 0.001
CVP (mmHg)
11.6 ± 5.7
10.3 ± 4.9
14.3 ± 6.3
< 0.001
10.4 ± 5.1
12.2 ± 5.9
0.031
PIP (cmH2O)
23.9 ± 6.2
22.6 ± 6.0
27.2 ± 5.2
< 0.001
22.5 ± 6.5
24.8 ± 5.7
0.006
PEEP (cmH2O)
9.2 ± 4.2
8.5 ± 4.1
11.2 ± 3.7
< 0.001
7.8 ± 4.1
10.2 ± 3.9
< 0.001
Lactate (mmol/l)
4.6 ± 5.4
4.4 ± 4.6
4.9 ± 6.9
0.519
4.4 ± 4.9
4.7 ± 5.7
0.741
FI (
124 [47.0]
69 [35.9]
55 [76.4]
< 0.001
-
-
IAH (
42 [15.9]
-
-
3 [2.7]
39 [25.3]
< 0.001
Gastrointestinal failure (FI+IAH;
36 [13.6]
-
36 [50.0]
-
36 [23.4]
Outcome parameters
MV (days)
7.4 ± 11.9
4.3 ± 6.1
15.5 ± 18.0
< 0.001
3.6 ± 5.9
10.0 ± 14.1
< 0.001
ICU stay (days)
8.8 ± 12.8
5.6 ± 7.3
17.5 ± 19.0
< 0.001
4.8 ± 6.9
11.7 ± 15.1
< 0.001
ICU mortality (
39 [14.8]
21 [10.9]
18 [25.0]
0.005
7 [6.4]
32 [20.8]
0.001
28-day mortality (
54 [20.5]
36 [18.8]
18 [25.0]
0.171
13 [11.8]
41 [26.6]
< 0.001
90-day mortality (
75 [28.4]
48 [25.0]
27 [37.5]
0.033
17 [15.5]
58 [37.7]
0.002
The values are presented as mean ± standard deviation, if not stated otherwise. APACHE, Acute Physiology and Chronic Health Evaluation; BMI, body mass index; CVP, central venous pressure; FI, food intolerance; IAH, intra-abdominal hypertension; IAP, intra-abdominal pressure; ICU, intensive care unit; MAP, mean arterial pressure; MV, mechanical ventilation; PEEP, positive end-expiratory pressure; PIP, peak inspiratory pressure; SOFA, Sequential Organ Failure Assessment.
Table
Competing interests
The authors declare that they have no competing interests.