bcr677 BCJ Oral presentation <p>Clinical breast cancer and estrogen</p> Chew HK

UC Davis Cancer Center, Sacramento, California, USA

 Breast Cancer Res <p>24<sup>th </sup>Congress of the International Association for Breast Cancer Research. Advances in human breast cancer research: preclinical models</p> Meeting abstracts <p>24<sup>th </sup>Congress of the International Association for Breast Cancer Research. Advances in human breast cancer research: preclinical models</p> Sacramento, USA 1-5 November 2003 1465-5411 2003 5 Suppl 1 18 10.1186/bcr677 31 10 2003

Endocrine therapy, targeting estrogen production or the estrogen receptor, is a crucial component in the treatment of breast cancer. This has been recognized for over a century. Ovarian ablation is the oldest form of endocrine therapy, first used in 1896. This presentation will review: the history of endocrine therapy in the treatment of breast cancer; endocrine strategies in premenopausal and postmenopausal women; data on the use of endocrine therapy in early breast cancer; new directions in the endocrine therapy of metastatic breast cancer; and clinical implications of HER2-neu status and endocrine therapy.