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Immunotherapy against cancer and immune disorders

Edited by Dr John T. Kung

This article collection, published in Journal of Biomedical Science, is dedicated to reviewing studies that use various different approaches that target activation of distinct immune cell pathways to therapeutically treat cancer and immune disorders.

This series of articles has not been sponsored. All articles have undergone the journal's standard peer review process overseen by the Guest Editor. The Guest Editor declares no competing interests.

  1. Immune checkpoints or coinhibitory receptors, such as cytotoxic T lymphocyte antigen (CTLA)-4 and programmed death (PD)-1, play important roles in regulating T cell responses, and they were proven to be effect...

    Authors: Hwei-Fang Tsai and Ping-Ning Hsu
    Citation: Journal of Biomedical Science 2017 24:35
  2. Immunotherapy has recently emerged as the fourth pillar of cancer treatment, joining surgery, radiation, and chemotherapy. While early immunotherapies focused on accelerating T-cell activity, current immune-ch...

    Authors: Yoshiko Iwai, Junzo Hamanishi, Kenji Chamoto and Tasuku Honjo
    Citation: Journal of Biomedical Science 2017 24:26
  3. Immune interferon (IFN), also known as IFN-γ, promotes not only immunomodulation but also antimicrobial and anticancer activity. After IFN-γ binds to the complex of IFN-γ receptor (IFNGR) 1-IFNGR2 and subseque...

    Authors: Chiou-Feng Lin, Chih-Ming Lin, Kang-Yun Lee, Szu-Yuan Wu, Po-Hao Feng, Kuan-Yuan Chen, Hsiao-Chi Chuang, Chia-Ling Chen, Yu-Chih Wang, Po-Chun Tseng and Tsung-Ting Tsai
    Citation: Journal of Biomedical Science 2017 24:10
  4. Human mesenchymal stem cells (MSCs) are multilineage somatic progenitor/stem cells that have been shown to possess immunomodulatory properties in recent years. Initially met with much skepticism, MSC immunomod...

    Authors: Li-Tzu Wang, Chiao-Hsuan Ting, Men-Luh Yen, Ko-Jiunn Liu, Huey-Kang Sytwu, Kenneth K. Wu and B. Linju Yen
    Citation: Journal of Biomedical Science 2016 23:76
  5. Human papillomavirus (HPV) infections and associated diseases remain a serious burden worldwide. It is now clear that HPV serves as the etiological factor and biologic carcinogen for HPV-associated lesions and...

    Authors: Andrew Yang, Emily Farmer, T. C. Wu and Chien-Fu Hung
    Citation: Journal of Biomedical Science 2016 23:75
  6. To better evaluate and improve the efficacy of dendritic cell (DC)-based cancer immunotherapy, we conducted a clinical study of patients with advanced colorectal cancer using carcinoembryonic antigen (CEA)-pul...

    Authors: Ko-Jiunn Liu, Tsu-Yi Chao, Jang-Yang Chang, Ann-Lii Cheng, Hui-Ju Ch’ang, Woei-Yau Kao, Yu-Chen Wu, Wei-Lan Yu, Tsai-Rong Chung and Jacqueline Whang-Peng
    Citation: Journal of Biomedical Science 2016 23:64