biomedcentral.com/bmcsystbiol/article
Bottom,Top,Right1
  • Welcome Stanford University
  • Log on
  •   BioMed Central
  • Journals
  • Gateways
BMC Systems Biology
official impact factor 2.98
Search for
Advanced search
  • Home
  • Articles
  • Authors
  • Reviewers
  • About this journal
  • My BMC Systems Biology

Submit a manuscript Register Sign up for article alerts Contact us Follow us on Twitter

Explore BMC Systems Biology

  •  Editorial Board
  •  Instructions for authors
  •  FAQ
Advertisement

Articles

  • All articles RSS
  • Sections
  • Most viewed RSS
  • Archive
  • Supplements
Synthetic biology Section edited by Sang Yup Lee

This section covers the application of systems biology, biotechnology and an engineering approach to the design and construction of novel biological functions, and in particular those with industrial or biomedical importance.

Page 1 of 3

1 2 3  Next

 Display/download options Articles per page: 25 | 50 | 100

Display options
Download optionsHelp icon

1.

Research article   Open Access Highly Accessed

Inferring ancient metabolism using ancestral core metabolic models of enterobacteria

David J Baumler, Bing Ma, Jennifer L Reed, Nicole T Perna BMC Systems Biology 2013, 7:46 (11 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

2.

Methodology article   Open Access Highly Accessed

Modular, rule-based modeling for the design of eukaryotic synthetic gene circuits

Mario Marchisio, Moreno Colaiacovo, Ellis Whitehead, Jörg Stelling BMC Systems Biology 2013, 7:42 (27 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

3.

Research article   Open Access Highly Accessed

Probabilistic strain optimization under constraint uncertainty

Mona Yousofshahi, Michael Orshansky, Kyongbum Lee, Soha Hassoun BMC Systems Biology 2013, 7:29 (29 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

Research article   Open Access

Mapping global effects of the anti-sigma factor MucA in Pseudomonas fluorescens SBW25 through genome-scale metabolic modeling

Sven EF Borgos, Sergio Bordel, Håvard Sletta, Helga Ertesvåg, Øyvind Jakobsen, Per Bruheim, Trond E Ellingsen, Jens Nielsen, Svein Valla BMC Systems Biology 2013, 7:19 (11 March 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Genome-scale metabolic modelling and chemostat experiments identify the genomic features in Pseudomonas fluorescens necessary to develop highly productive strains and optimal conditions for the industrial production of the important polysaccharide gel alginate, currently produced from seaweed.

5.

Research article   Open Access

Glucose-methanol co-utilization in Pichia pastoris studied by metabolomics and instationary 13C flux analysis

Joel Jordà, Camilo Suarez, Marc Carnicer, Angela ten Pierick, Joseph J Heijnen, Walter van Gulik, Pau Ferrer, Joan Albiol, Aljoscha Wahl BMC Systems Biology 2013, 7:17 (28 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

6.

Methodology article   Open Access Highly Accessed

Computational codon optimization of synthetic gene for protein expression

Bevan Chung, Dong-Yup Lee BMC Systems Biology 2012, 6:134 (20 October 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A novel method for codon usage optimization in artificial gene synthesis, optimizing use of both individual codon usage and codon context approaches, is predicted to lead to improved in vitro heterologous protein expression in biotechnology applications.

7.

Research article   Open Access

Gene autoregulation via intronic microRNAs and its functions

Carla Bosia, Matteo Osella, Mariama Baroudi, Davide Corà, Michele Caselle BMC Systems Biology 2012, 6:131 (10 October 2012)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access Highly Accessed

Comparative multi-goal tradeoffs in systems engineering of microbial metabolism

David Byrne, Alexandra Dumitriu, Daniel Segrè BMC Systems Biology 2012, 6:127 (26 September 2012)

Abstract | Full text | PDF | PubMed

9.

Research article   Open Access Highly Accessed

A reconfigurable NAND/NOR genetic logic gate

Angel Goñi-Moreno, Martyn Amos BMC Systems Biology 2012, 6:126 (18 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A novel genetic circuit is proposed and computationally tested that can be dynamically reconfigured to serve as either a NAND or NOR genetic logic gate in either single cells or cell populations.

10.

Methodology article   Open Access

Designing optimal cell factories: integer programming couples elementary mode analysis with regulation

Christian Jungreuthmayer, Jürgen Zanghellini BMC Systems Biology 2012, 6:103 (16 August 2012)

Abstract | Full text | PDF | PubMed

Page 1 of 3

1 2 3  Next


  • Terms and Conditions
  • Privacy statement
  • Press
  • Information for advertisers
  • Jobs at BMC
  • Support
  • Contact us

© 2013 BioMed Central Ltd unless otherwise stated. Part of Springer Science+Business Media.