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Volume 4 (2010) - March 2010

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Research article   Open Access

An integrated machine learning approach for predicting DosR-regulated genes in Mycobacterium tuberculosis

Yi Zhang, Kim A Hatch, Joanna Bacon, Lorenz Wernisch BMC Systems Biology 2010, 4:37 (31 March 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Building and analyzing protein interactome networks by cross-species comparisons

Amy M Wiles, Mark Doderer, Jianhua Ruan, Ting-Ting Gu, Dashnamoorthy Ravi, Barron Blackman, Alexander JR Bishop BMC Systems Biology 2010, 4:36 (30 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access Highly Accessed

Prediction of novel synthetic pathways for the production of desired chemicals

Ayoun Cho, Hongseok Yun, Jin Park, Sang Lee, Sunwon Park BMC Systems Biology 2010, 4:35 (28 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Stochastic and deterministic multiscale models for systems biology: an auxin-transport case study

Jamie Twycross, Leah R Band, Malcolm J Bennett, John R King, Natalio Krasnogor BMC Systems Biology 2010, 4:34 (26 March 2010)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

Automated characterization of cell shape changes during amoeboid motility by skeletonization

Yuan Xiong, Cathryn Kabacoff, Jonathan Franca-Koh, Peter N Devreotes, Douglas N Robinson, Pablo A Iglesias BMC Systems Biology 2010, 4:33 (24 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Linking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans

Suresh Swain, Jodie F Wren, Stephen R Stürzenbaum, Peter Kille, A John Morgan, Tjalling Jager, Martijs J Jonker, Peter K Hankard, Claus Svendsen, Jenifer Owen, B Ann Hedley, Mark Blaxter, David J Spurgeon BMC Systems Biology 2010, 4:32 (23 March 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Genome-scale metabolic analysis of Clostridium thermocellum for bioethanol production

Seth B Roberts, Christopher M Gowen, J Paul Brooks, Stephen S Fong BMC Systems Biology 2010, 4:31 (22 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Genotype networks in metabolic reaction spaces

Areejit Samal, João F Matias Rodrigues, Jürgen Jost, Olivier C Martin, Andreas Wagner BMC Systems Biology 2010, 4:30 (19 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

A novel approach to investigate tissue-specific trinucleotide repeat instability

Jong-Min Lee, Jie Zhang, Andrew I Su, John R Walker, Tim Wiltshire, Kihwa Kang, Ella Dragileva, Tammy Gillis, Edith T Lopez, Marie-Josee Boily, Michel Cyr, Isaac Kohane, James F Gusella, Marcy E MacDonald, Vanessa C Wheeler BMC Systems Biology 2010, 4:29 (19 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

Methodology article   Open Access

Zooming of states and parameters using a lumping approach including back-translation

Mikael Sunnåker, Henning Schmidt, Mats Jirstrand, Gunnar Cedersund BMC Systems Biology 2010, 4:28 (18 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

A predictive computational model of the kinetic mechanism of stimulus-induced transducer methylation and feedback regulation through CheY in archaeal phototaxis and chemotaxis

Stefan Streif, Dieter Oesterhelt, Wolfgang Marwan BMC Systems Biology 2010, 4:27 (18 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

The internal state of medium spiny neurons varies in response to different input signals

Zhen Qi, Gary W Miller, Eberhard O Voit BMC Systems Biology 2010, 4:26 (17 March 2010)

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Research article   Open Access

Brownian diffusion of AMPA receptors is sufficient to explain fast onset of LTP

Dominic P Tolle, Nicolas Le Novère BMC Systems Biology 2010, 4:25 (16 March 2010)

Abstract | Full text | PDF | PubMed

Software   Open Access

Meredys, a multi-compartment reaction-diffusion simulator using multistate realistic molecular complexes

Dominic P Tolle, Nicolas Le Novère BMC Systems Biology 2010, 4:24 (16 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Two additive mechanisms impair the differentiation of 'substrate-selective' p38 inhibitors from classical p38 inhibitors in vitro

Bart S Hendriks, Kelly M Seidl, Jeffrey R Chabot BMC Systems Biology 2010, 4:23 (15 March 2010)

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Correspondence   Open Access Highly Accessed

So what do we really mean when we say that systems biology is holistic?

Derek Gatherer BMC Systems Biology 2010, 4:22 (12 March 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Parameter estimation and inference for stochastic reaction-diffusion systems: application to morphogenesis in D. melanogaster

Michael A Dewar, Visakan Kadirkamanathan, Manfred Opper, Guido Sanguinetti BMC Systems Biology 2010, 4:21 (10 March 2010)

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Research article   Open Access Highly Accessed

Integrated cellular network of transcription regulations and protein-protein interactions

Yu-Chao Wang, Bor-Sen Chen BMC Systems Biology 2010, 4:20 (8 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Probability distributed time delays: integrating spatial effects into temporal models

Tatiana T Marquez-Lago, André Leier, Kevin Burrage BMC Systems Biology 2010, 4:19 (4 March 2010)

Abstract | Full text | PDF | PubMed | 1 comment

Research article   Open Access Highly Accessed

Statistical model comparison applied to common network motifs

Núria Domedel-Puig, Iosifina Pournara, Lorenz Wernisch BMC Systems Biology 2010, 4:18 (3 March 2010)

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Research article   Open Access Highly Accessed

Reverse engineering a gene network using an asynchronous parallel evolution strategy

Luke Jostins, Johannes Jaeger BMC Systems Biology 2010, 4:17 (2 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central


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