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Volume 4 (2010) - August 2010

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Research article   Open Access Highly Accessed

Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis

Carola Huthmacher, Andreas Hoppe, Sascha Bulik, Hermann-Georg Holzhütter BMC Systems Biology 2010, 4:120 (31 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Ultrasensitive Responses and Specificity in Cell Signaling

Seth Haney, Lee Bardwell, Qing Nie BMC Systems Biology 2010, 4:119 (25 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Systems approach to investigating host-pathogen interactions in infections with the biothreat agent Francisella. Constraints-based model of Francisella tularensis

Anu Raghunathan, Sookil Shin, Simon Daefler BMC Systems Biology 2010, 4:118 (23 August 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Curating the innate immunity interactome

David J Lynn, Calvin Chan, Misbah Naseer, Melissa Yau, Raymond Lo, Anastasia Sribnaia, Giselle Ring, Jaimmie Que, Kathleen Wee, Geoffrey L Winsor, Matthew R Laird, Karin Breuer, Amir K Foroushani, Fiona SL Brinkman, Robert EW Hancock BMC Systems Biology 2010, 4:117 (20 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Integrative inference of gene-regulatory networks in Escherichia coli using information theoretic concepts and sequence analysis

Christoph Kaleta, Anna Göhler, Stefan Schuster, Knut Jahreis, Reinhard Guthke, Swetlana Nikolajewa BMC Systems Biology 2010, 4:116 (18 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Validation of a constraint-based model of Pichia pastoris metabolism under data scarcity

Marta Tortajada, Francisco Llaneras, Jesús Picó BMC Systems Biology 2010, 4:115 (17 August 2010)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Integration of metabolic databases for the reconstruction of genome-scale metabolic networks

Karin Radrich, Yoshimasa Tsuruoka, Paul Dobson, Albert Gevorgyan, Neil Swainston, Gino Baart, Jean-Marc Schwartz BMC Systems Biology 2010, 4:114 (16 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Optimization strategies for metabolic networks

Alexandre Domingues, Susana Vinga, João M Lemos BMC Systems Biology 2010, 4:113 (13 August 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Systems analysis of iron metabolism: the network of iron pools and fluxes

Tiago JS Lopes, Tatyana Luganskaja, Maja Vujić Spasić, Matthias W Hentze, Martina U Muckenthaler, Klaus Schümann, Jens G Reich BMC Systems Biology 2010, 4:112 (13 August 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Modeling the global effect of the basic-leucine zipper transcription factor 1 (bZIP1) on nitrogen and light regulation in Arabidopsis

Mariana Obertello, Gabriel Krouk, Manpreet S Katari, Suzan J Runko, Gloria M Coruzzi BMC Systems Biology 2010, 4:111 (12 August 2010)

Abstract | Full text | PDF | PubMed | F1000 Biology

Methodology article   Open Access

Simulation methods with extended stability for stiff biochemical Kinetics

Pau Rué, Jordi Villà-Freixa, Kevin Burrage BMC Systems Biology 2010, 4:110 (11 August 2010)

Abstract | Full text | PDF | PubMed

Software   Open Access

DBSolve Optimum: a software package for kinetic modeling which allows dynamic visualization of simulation results

Nail M Gizzatkulov, Igor I Goryanin, Eugeny A Metelkin, Ekaterina A Mogilevskaya, Kirill V Peskov, Oleg V Demin BMC Systems Biology 2010, 4:109 (10 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Bridging time scales in cellular decision making with a stochastic bistable switch

Steffen Waldherr, Jingbo Wu, Frank Allgöwer BMC Systems Biology 2010, 4:108 (9 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access

Integrative multicellular biological modeling: a case study of 3D epidermal development using GPU algorithms

Scott Christley, Briana Lee, Xing Dai, Qing Nie BMC Systems Biology 2010, 4:107 (9 August 2010)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Model-based extension of high-throughput to high-content data

Andrea C Pfeifer, Daniel Kaschek, Julie Bachmann, Ursula Klingmüller, Jens Timmer BMC Systems Biology 2010, 4:106 (5 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Integrative analysis of large scale expression profiles reveals core transcriptional response and coordination between multiple cellular processes in a cyanobacterium

Abhay K Singh, Thanura Elvitigala, Jeffrey C Cameron, Bijoy K Ghosh, Maitrayee Bhattacharyya-Pakrasi, Himadri B Pakrasi BMC Systems Biology 2010, 4:105 (2 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central


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