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Editor-in-Chief Melissa Norton, MD Biology Editor Penelope Webb, PhD In-house Editor Tim Sands PhD
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| | BMC Systems Biology, Volume 3 | | Software
    DASMiner: discovering and integrating data from DAS sources Diogo F T Veiga, Helena F Deus, Caner Akdemir, Ana Tereza R Vasconcelos, Jonas S Almeida BMC Systems Biology 2009, 3:109 (17 November 2009) [Abstract] [Provisional PDF] [PubMed] [Related articles] Research article
    Network analysis of the transcriptional pattern of young and old cells of Escherichia coli during lag phase Carmen Pin, Matthew D Rolfe, Marina Mu oz-Cuevas, Jay CD Hinton, Michael W Peck, Nicholas J Walton, J zsef Baranyi BMC Systems Biology 2009, 3:108 (16 November 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Long-term prediction of fish growth under varying ambient temperatures using a multiscale dynamic model Nadav S Bar, Nicole Radde BMC Systems Biology 2009, 3:107 (10 November 2009) [Abstract] [Provisional PDF] [PubMed] [Related articles] Methodology article
    Using the ratio of means as the effect size measure in combining results of microarray experiments Pingzhao Hu, Celia MT Greenwood, Joseph Beyene BMC Systems Biology 2009, 3:106 (5 November 2009) [Abstract] [Provisional PDF] [PubMed] [Related articles] Research article
    A model invalidation-based approach for elucidating biological signalling pathways, applied to the chemotaxis pathway in R. sphaeroides Mark AJ Roberts, Elias August, Abdullah Hamadeh, Philip K Maini, Patrick E McSharry, Judith P Armitage, Antonis Papachristodoulou BMC Systems Biology 2009, 3:105 (31 October 2009) [Abstract] [Provisional PDF] [PubMed] [Related articles] Research article
    13C-metabolic flux ratio and novel carbon path analyses confirmed that Trichoderma reesei uses primarily the respirative pathway also on the preferred carbon source glucose Paula Jouhten, Esa Pitk nen, Tiina Pakula, Markku Saloheimo, Merja Penttil , Hannu Maaheimo BMC Systems Biology 2009, 3:104 (29 October 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Methodology article
     Inferring branching pathways in genome-scale metabolic networks Esa Pitkanen, Paula Jouhten, Juho Rousu BMC Systems Biology 2009, 3:103 (29 October 2009) [Abstract] [Provisional PDF] [PubMed] [Related articles] [Cited on BioMed Central] Research article
     How to identify essential genes from molecular networks? Gabriel del Rio, Dirk Kosch tzki, Gerardo Coello BMC Systems Biology 2009, 3:102 (13 October 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Investigating the robustness of the classical enzyme kinetic equations in small intracellular compartments Ramon Grima BMC Systems Biology 2009, 3:101 (8 October 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway Richard J Orton, Michiel E Adriaens, Amelie Gormand, Oliver E Sturm, Walter Kolch, David R Gilbert BMC Systems Biology 2009, 3:100 (5 October 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Software
     An editor for pathway drawing and data visualization in the Biopathways Workbench Robert W Byrnes, Dawn Cotter, Andreia Maer, Joshua Li, David Nadeau, Shankar Subramaniam BMC Systems Biology 2009, 3:99 (2 October 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Methodology article
     Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling Dominik M Wittmann, Jan Krumsiek, Julio Saez-Rodriguez, Douglas A Lauffenburger, Steffen Klamt, Fabian J Theis BMC Systems Biology 2009, 3:98 (28 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Modeling system states in liver cells: Survival, apoptosis and their modifications in response to viral infection Nicole Philippi, Dorothee Walter, Rebekka Schlatter, Karine Ferreira, Michael Ederer, Oliver Sawodny, Jens Timmer, Christoph Borner, Thomas Dandekar BMC Systems Biology 2009, 3:97 (22 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    The capacity for multistability in small gene regulatory networks Dan Siegal-Gaskins, Erich Grotewold, Gregory D Smith BMC Systems Biology 2009, 3:96 (21 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    A method for determining the robustness of bio-molecular oscillator models Reza Ghaemi, Jing Sun, Pablo A Iglesias, Domitilla Del Vecchio BMC Systems Biology 2009, 3:95 (21 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Inferring Drosophila gap gene regulatory network: a parameter sensitivity and perturbation analysis Yves Fomekong-Nanfack, Marten Postma, Jaap A Kaandorp BMC Systems Biology 2009, 3:94 (21 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Dissecting the fission yeast regulatory network reveals phase-specific control elements of its cell cycle Pierre R Bushel, Nicholas A Heard, Roee Gutman, Liwen Liu, Shyamal D Peddada, Saumyadipta Pyne BMC Systems Biology 2009, 3:93 (16 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     A systems biology framework for modeling metabolic enzyme inhibition of Mycobacterium tuberculosis Xin Fang, Anders Wallqvist, Jaques Reifman BMC Systems Biology 2009, 3:92 (15 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Metabolism as means for hypoxia adaptation: metabolic profiling and flux balance analysis Jacob D Feala, Laurence Coquin, Dan Zhou, Gabriel G Haddad, Giovanni Paternostro, Andrew D McCulloch BMC Systems Biology 2009, 3:91 (9 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     The smallest chemical reaction system with bistability Thomas Wilhelm BMC Systems Biology 2009, 3:90 (8 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Hybrid stochastic simplifications for multiscale gene networks Alina Crudu, Arnaud Debussche, Ovidiu Radulescu BMC Systems Biology 2009, 3:89 (7 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     The crosstalk between EGF, IGF, and Insulin cell signaling pathways - computational and experimental analysis Rafal Zielinski, Pawel F Przytycki, Jie Zheng, David Zhang, Teresa M Przytycka, Jacek Capala BMC Systems Biology 2009, 3:88 (4 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    The genotype-phenotype relationship in multicellular pattern-generating models - the neglected role of pattern descriptors Harald Martens, Siren R Veflingstad, Erik Plahte, Magni Martens, Dominique Bertrand, Stig W Omholt BMC Systems Biology 2009, 3:87 (4 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Large-scale analysis of Arabidopsis transcription reveals a basal co-regulation network Osnat Atias, Benny Chor, Daniel A Chamovitz BMC Systems Biology 2009, 3:86 (3 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     From gene expression to gene regulatory networks in Arabidopsis thaliana Chris J Needham, Iain W Manfield, Andrew J Bulpitt, Philip M Gilmartin, David R Westhead BMC Systems Biology 2009, 3:85 (3 September 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Specialized or flexible feed-forward loop motifs: a question of topology Javier Mac a, Stefanie Widder, Ricard Sol BMC Systems Biology 2009, 3:84 (31 August 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Monte Carlo analysis of an ODE Model of the Sea Urchin Endomesoderm Network Clemens K hn, Christoph Wierling, Alexander K hn, Edda Klipp, Georgia Panopoulou, Hans Lehrach, Albert J Poustka BMC Systems Biology 2009, 3:83 (23 August 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Software
     Visualizing post genomics data-sets on customized pathway maps by ProMeTra aeration-dependent gene expression and metabolism of Corynebacterium glutamicum as an example Heiko Neuweger, Marcus Persicke, Stefan P Albaum, Thomas Bekel, Michael Dondrup, Andrea T H ser, J rn Winnebald, Jessica Schneider, J rn Kalinowski, Alexander Goesmann BMC Systems Biology 2009, 3:82 (23 August 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Optimal drug combinations and minimal hitting sets Alexei Vazquez BMC Systems Biology 2009, 3:81 (6 August 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Knowledge based identification of essential signaling from genome-scale siRNA experiments Armand Bankhead III, Iliana Sach, Chester Ni, Nolwenn LeMeur, Mark Kruger, Marc Ferrer, Robert Gentleman, Carol Rohl BMC Systems Biology 2009, 3:80 (5 August 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Methodology article
     A possibilistic framework for constraint-based metabolic flux analysis Francisco Llaneras, Antonio Sala, Jes s Pic BMC Systems Biology 2009, 3:79 (31 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     A dynamic network of transcription in LPS-treated human subjects Junhee Seok, Wenzhong Xiao, Lyle L Moldawer, Ronald W Davis, Markus W Covert BMC Systems Biology 2009, 3:78 (28 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Adapted Boolean network models for extracellular matrix formation Johannes Wollbold, Ren Huber, Dirk Pohlers, Dirk Koczan, Reinhard Guthke, Raimund W Kinne, Ulrike Gausmann BMC Systems Biology 2009, 3:77 (21 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Hierarchical coordination of periodic genes in the cell cycle of Saccharomyces cerevisiae Frank Emmert-Streib, Matthias Dehmer BMC Systems Biology 2009, 3:76 (20 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Hypothesis
    Calculation of the relative metastabilities of proteins in subcellular compartments of Saccharomyces cerevisiae Jeffrey M Dick BMC Systems Biology 2009, 3:75 (18 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions Roland A Pache, M Madan Babu, Patrick Aloy BMC Systems Biology 2009, 3:74 (18 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules Huaxia Qin, Michael WY Chan, Sandya Liyanarachchi, Curtis Balch, Dustin Potter, Irene J Souriraj, Alfred SL Cheng, Francisco J Agosto-Perez, Elena V Nikonova, Pearlly S Yan, Huey-Jen Lin, Kenneth P Nephew, Joel H Saltz, Louise C Showe, Tim HM Huang, Ramana V Davuluri BMC Systems Biology 2009, 3:73 (17 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Cascading signaling pathways improve the fidelity of a stochastically and deterministically simulated molecular RS latch Evan Mills, Kevin Truong BMC Systems Biology 2009, 3:72 (17 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Mechanism of PP2A-mediated IKK dephosphorylation: a systems biological approach Johannes Witt, Sandra Barisic, Eva Schumann, Frank Allg wer, Oliver Sawodny, Thomas Sauter, Dagmar Kulms BMC Systems Biology 2009, 3:71 (16 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Deterministic mathematical models of the cAMP pathway in Saccharomyces cerevisiae Thomas Williamson, Jean-Marc Schwartz, Douglas B Kell, Lubomira Stateva BMC Systems Biology 2009, 3:70 (16 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Interactome and Gene Ontology provide congruent yet subtly different views of a eukaryotic cell Antonio Marco, Ignacio Mar n BMC Systems Biology 2009, 3:69 (15 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Computing phenomenologic Adair-Klotz constants from microscopic MWC parameters Melanie I Stefan, Stuart J Edelstein, Nicolas Le Nov re BMC Systems Biology 2009, 3:68 (14 July 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Methodology article
     BowTieBuilder: modeling signal transduction pathways Jochen Supper, Luc a Spangenberg, Hannes Planatscher, Andreas Dr ger, Adrian Schr der, Andreas Zell BMC Systems Biology 2009, 3:67 (30 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     A systematic design method for robust synthetic biology to satisfy design specifications Bor-Sen Chen, Chih-Hung Wu BMC Systems Biology 2009, 3:66 (30 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Clustered microRNAs' coordination in regulating protein-protein interaction network Xiongying Yuan, Changning Liu, Pengcheng Yang, Shunmin He, Qi Liao, Shuli Kang, Yi Zhao BMC Systems Biology 2009, 3:65 (26 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Stochastic simulation and analysis of biomolecular reaction networks John M Frazier, Yaroslav Chushak, Brent Foy BMC Systems Biology 2009, 3:64 (17 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     The Symbiosis Interactome: a computational approach reveals novel components, functional interactions and modules in Sinorhizobium meliloti Ignacio Rodriguez-Llorente, Miguel A Caviedes, Mohammed Dary, Antonio J Palomares, Francisco M C novas, Jos M Peregr n-Alvarez BMC Systems Biology 2009, 3:63 (16 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Serial evolutionary networks of within-patient HIV-1 sequences reveal patterns of evolution of X4 strains Patricia Buendia, Giri Narasimhan BMC Systems Biology 2009, 3:62 (16 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Intervention in gene regulatory networks via greedy control policies based on long-run behavior Xiaoning Qian, Ivan Ivanov, Noushin Ghaffari, Edward R Dougherty BMC Systems Biology 2009, 3:61 (15 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     The mathematics of tanning Josef Thingnes, Leiv yehaug, Eivind Hovig, Stig W Omholt BMC Systems Biology 2009, 3:60 (9 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     A system biology approach highlights a hormonal enhancer effect on regulation of genes in a nitrate responsive "biomodule" Damion Nero, Gabriel Krouk, Daniel Tranchina, Gloria M Coruzzi BMC Systems Biology 2009, 3:59 (6 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] [1 comment] Software
     ChemChains: a platform for simulation and analysis of biochemical networks aimed to laboratory scientists Tom Helikar, Jim A Rogers BMC Systems Biology 2009, 3:58 (6 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Database
     LeishCyc: a biochemical pathways database for Leishmania major Maria A Doyle, James I MacRae, David P De Souza, Eleanor C Saunders, Malcolm J McConville, Vladimir A Liki BMC Systems Biology 2009, 3:57 (5 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Commentary
     Computational disease modeling fact or fiction? Jesper N Tegn r, Albert Compte, Charles Auffray, Gary An, Gunnar Cedersund, Gilles Clermont, Boris Gutkin, Zolt n N Oltvai, Klaas Enno Stephan, Randy Thomas, Pablo Villoslada BMC Systems Biology 2009, 3:56 (4 June 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Methodology article
     A graphical model approach for inferring large-scale networks integrating gene expression and genetic polymorphism Jen-hwa Chu, Scott T Weiss, Vincent J Carey, Benjamin A Raby BMC Systems Biology 2009, 3:55 (27 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Inference of gene pathways using mixture Bayesian networks Younhee Ko, ChengXiang Zhai, Sandra Rodriguez-Zas BMC Systems Biology 2009, 3:54 (19 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Methodology article
     An approach to evaluate the topological significance of motifs and other patterns in regulatory networks Bj rn Goemann, Edgar Wingender, Anatolij P Potapov BMC Systems Biology 2009, 3:53 (19 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Proteomic and network analysis characterize stage-specific metabolism in Trypanosoma cruzi Seth B Roberts, Jennifer L Robichaux, Arvind K Chavali, Patricio A Manque, Vladimir Lee, Ana M Lara, Jason A Papin, Gregory A Buck BMC Systems Biology 2009, 3:52 (16 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    On the functional diversity of dynamical behaviour in genetic and metabolic feedback systems Lan K Nguyen, Don Kulasiri BMC Systems Biology 2009, 3:51 (11 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Systematic identifiability testing for unambiguous mechanistic modeling application to JAK-STAT, MAP kinase, and NF- B signaling pathway models Tom Quaiser, Martin M nnigmann BMC Systems Biology 2009, 3:50 (9 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Comparative analysis of module-based versus direct methods for reverse-engineering transcriptional regulatory networks Tom Michoel, Riet De Smet, Anagha Joshi, Yves Van de Peer, Kathleen Marchal BMC Systems Biology 2009, 3:49 (7 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Information flow during gene activation by signaling molecules: ethylene transduction in Arabidopsis cells as a study system Jos D az, Elena R Alvarez-Buylla BMC Systems Biology 2009, 3:48 (5 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Identification of neutral biochemical network models from time series data Marco Vilela, Susana Vinga, Marco A Grivet Mattoso Maia, Eberhard O Voit, Jonas S Almeida BMC Systems Biology 2009, 3:47 (5 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Genetic and environmental pathways to complex diseases Julia M Gohlke, Reuben Thomas, Yonqing Zhang, Michael C Rosenstein, Allan P Davis, Cynthia Murphy, Kevin G Becker, Carolyn J Mattingly, Christopher J Portier BMC Systems Biology 2009, 3:46 (5 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     miRNA-regulated dynamics in circadian oscillator models Amitabha Nandi, Candida Vaz, Alok Bhattacharya, Ramakrishna Ramaswamy BMC Systems Biology 2009, 3:45 (5 May 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Using in silico models to simulate dual perturbation experiments: procedure development and interpretation of outcomes Neema Jamshidi, Bernhard O Palsson BMC Systems Biology 2009, 3:44 (30 April 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    A combinatorial approach to determine the context-dependent role in transcriptional and posttranscriptional regulation in Arabidopsis thaliana Le Lu, Jinming Li BMC Systems Biology 2009, 3:43 (28 April 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Simulation-based model checking approach to cell fate specification during Caenorhabditis elegans vulval development by hybrid functional Petri net with extension Chen Li, Masao Nagasaki, Kazuko Ueno, Satoru Miyano BMC Systems Biology 2009, 3:42 (27 April 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Methodology article
     Recursive regularization for inferring gene networks from time-course gene expression profiles Teppei Shimamura, Seiya Imoto, Rui Yamaguchi, Andr Fujita, Masao Nagasaki, Satoru Miyano BMC Systems Biology 2009, 3:41 (22 April 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Narrative-based computational modelling of the Gp130/JAK/STAT signalling pathway Maria Luisa Guerriero, Anna Dudka, Nicholas Underhill-Day, John K Heath, Corrado Priami BMC Systems Biology 2009, 3:40 (15 April 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Reconstruction of Escherichia coli transcriptional regulatory networks via regulon-based associations Hossein Zare, Dipen Sangurdekar, Poonam Srivastava, Mostafa Kaveh, Arkady Khodursky BMC Systems Biology 2009, 3:39 (14 April 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Constraint-based analysis of metabolic capacity of Salmonella typhimurium during host-pathogen interaction Anu Raghunathan, Jennifer Reed, Sookil Shin, Bernhard Palsson, Simon Daefler BMC Systems Biology 2009, 3:38 (8 April 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Connecting extracellular metabolomic measurements to intracellular flux states in yeast Monica L Mo, Bernhard Palsson, Markus J Herrg rd BMC Systems Biology 2009, 3:37 (25 March 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central] Research article
     Identifying disease-specific genes based on their topological significance in protein networks Zolt n Dezs , Yuri Nikolsky, Tatiana Nikolskaya, Jeremy Miller, David Cherba, Craig Webb, Andrej Bugrim BMC Systems Biology 2009, 3:36 (23 March 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] [F1000 Biology] Research article
     Information processing in the transcriptional regulatory network of yeast: Functional robustness Frank Emmert-Streib, Matthias Dehmer BMC Systems Biology 2009, 3:35 (19 March 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central] Methodology article
    Version control of pathway models using XML patches Peter Saffrey, Richard Orton BMC Systems Biology 2009, 3:34 (17 March 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Reconstruction of metabolic pathways for the cattle genome Seongwon Seo, Harris A Lewin BMC Systems Biology 2009, 3:33 (12 March 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central] Research article
     Topological and organizational properties of the products of house-keeping and tissue-specific genes in protein-protein interaction networks Wen-hsien Lin, Wei-chung Liu, Ming-jing Hwang BMC Systems Biology 2009, 3:32 (11 March 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo Jesse J Smith, Ren e Deehan Kenney, David J Gagne, Brian P Frushour, William Ladd, Heidi L Galonek, Kristine Israelian, Jeffrey Song, Giedre Razvadauskaite, Amy V Lynch, David P Carney, Robin J Johnson, Siva Lavu, Andre Iffland, Peter J Elliott, Philip D Lambert, Keith O Elliston, Michael R Jirousek, Jill C Milne, Olivier Boss BMC Systems Biology 2009, 3:31 (10 March 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Methodology article
     Decomposing complex reaction networks using random sampling, principal component analysis and basis rotation Christian L Barrett, Markus J Herrgard, Bernhard Palsson BMC Systems Biology 2009, 3:30 (6 March 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Simple molecular networks that respond optimally to time-periodic stimulation Axel Cournac, Jacques-Alexandre Sepulchre BMC Systems Biology 2009, 3:29 (3 March 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Protein-protein interaction as a predictor of subcellular location Chang Jin Shin, Simon Wong, Melissa J Davis, Mark A Ragan BMC Systems Biology 2009, 3:28 (25 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Correspondence
     A framework for evolutionary systems biology Laurence Loewe BMC Systems Biology 2009, 3:27 (24 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Software
    FORG3D: Force-directed 3D graph editor for visualization of integrated genome scale data Jussi Paananen, Garry Wong BMC Systems Biology 2009, 3:26 (24 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Efficient, sparse biological network determination Elias August, Antonis Papachristodoulou BMC Systems Biology 2009, 3:25 (23 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central] Research article
    A fragile metabolic network adapted for cooperation in the symbiotic bacterium Buchnera aphidicola Gavin H Thomas, Jeremy Zucker, Sandy J Macdonald, Anatoly Sorokin, Igor Goryanin, Angela E Douglas BMC Systems Biology 2009, 3:24 (21 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Evolution of multiple phosphodiesterase isoforms in stickleback involved in cAMP signal transduction pathway Yukuto Sato, Yasuyuki Hashiguchi, Mutsumi Nishida BMC Systems Biology 2009, 3:23 (20 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central] Research article
    Roles of the creatine kinase system and myoglobin in maintaining energetic state in the working heart Fan Wu, Daniel A Beard BMC Systems Biology 2009, 3:22 (19 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
     Protein evolution on a human signaling network Qinghua Cui, Enrico O Purisima, Edwin Wang BMC Systems Biology 2009, 3:21 (18 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Using cell fate attractors to uncover transcriptional regulation of HL60 neutrophil differentiation Albert C Huang, Limei Hu, Stuart A Kauffman, Wei Zhang, Ilya Shmulevich BMC Systems Biology 2009, 3:20 (18 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    A module-based analytical strategy to identify novel disease-associated genes shows an inhibitory role for interleukin 7 Receptor in allergic inflammation Reza Mobini, Bengt A Andersson, Jonas Erjef lt, Mirjana Hahn-Zoric, Michael A Langston, Andy D Perkins, Lars Olaf Cardell, Mikael Benson BMC Systems Biology 2009, 3:19 (12 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central] Research article
    mRNA stability and the unfolding of gene expression in the long-period yeast metabolic cycle Nicola Soranzo, Mattia Zampieri, Lorenzo Farina, Claudio Altafini BMC Systems Biology 2009, 3:18 (6 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3 Donatella Cimini, Kiran R Patil, Chiara Schiraldi, Jens Nielsen BMC Systems Biology 2009, 3:17 (6 February 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Correspondence
    On gene dosage balance in protein complexes: a comment on Semple JI, Vavouri T, Lehner B. A simple principle concerning the robustness of protein complex activity to changes in gene expression. Reiner A Veitia BMC Systems Biology 2009, 3:16 (30 January 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Genome-scale constraint-based modeling of Geobacter metallireducens Jun Sun, Bahareh Sayyar, Jessica E Butler, Priti Pharkya, Tom R Fahland, Iman Famili, Christophe H Schilling, Derek R Lovley, Radhakrishnan Mahadevan BMC Systems Biology 2009, 3:15 (28 January 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Coordinations between gene modules control the operation of plant amino acid metabolic networks Hadar Less, Gad Galili BMC Systems Biology 2009, 3:14 (26 January 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting Amina A Qutub, Aleksander S Popel BMC Systems Biology 2009, 3:13 (26 January 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    Bifurcation analysis informs Bayesian inference in the Hes1 feedback loop Catherine F Higham BMC Systems Biology 2009, 3:12 (26 January 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Research article
    A Drosophila systems model of pentylenetetrazole induced locomotor plasticity responsive to antiepileptic drugs Farhan Mohammad, Priyanka Singh, Abhay Sharma BMC Systems Biology 2009, 3:11 (21 January 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles] Software
    SNAVI: Desktop application for analysis and visualization of large-scale signaling networks Avi Ma'ayan, Sherry L Jenkins, Ryan L Webb, Seth I Berger, Sudarshan P Purushothaman, Noura S Abul-Husn, Jeremy M Posner, Tony Flores, Ravi Iyengar BMC Systems Biology 2009, 3:10 (20 January 2009) [Abstract] [Full text] [PDF] [PubMed] [Related articles]
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