Crystal structure of the DNA polymerase III
β subunit ( β-clamp) from the extremophile Deinococcus radiodurans
Laila Niiranen, Kjersti Lian, Kenneth A Johnson, Elin Moe
BMC Structural Biology 2015, 15:5 (27 February 2015)
The crystal structure of the DNA polymerase III beta subunit from
Deinococcus radiodurans sheds light on the mechanisms of efficient DNA metabolism that enable this bacterium to survive high doses of radiation.
High-resolution structure of a type IV pilin from the metal-reducing bacterium
Manuela Gorgel, Jakob Ulstrup, Andreas Bøggild, Nykola C Jones, Søren V Hoffmann, Poul Nissen, Thomas Boesen
BMC Structural Biology 2015, 15:4 (27 February 2015)
Crystal structure and biophysical characterization of the nucleoside diphosphate kinase from
Plínio Vieira, Priscila de Giuseppe, Mario Murakami, Arthur de Oliveira
BMC Structural Biology 2015, 15:2 (3 February 2015)
The crystal structure of nucleoside diphosphate kinase from the parasite
L. braziliensis provides reveals a partially unfolded C-terminus that could serve as a potential target for drug therapies.
Structural insights into
Escherichia coli polymyxin B resistance protein D with X-ray crystallography and small-angle X-ray scattering
Hunho Jo, Eui Jeong, Jinseong Jeon, Changill Ban
BMC Structural Biology 2014, 14:24 (5 December 2014)
The structure of polymyxin B resistance protein D from
E. coli reveals distinct features differing from those of closely related species that may help determine its mechanisms of antibiotic resistance.
Structure and functional characterization of pyruvate decarboxylase from
Leonardo J van Zyl, Wolf-Dieter Schubert, Marla I Tuffin, Don A Cowan
BMC Structural Biology 2014, 14:21 (5 November 2014)
Gluconacetobacter diazotrophicus enzyme responsible for breaking down pyruvate into acetaldehyde and carbon dioxide, an important intermediate step in the production of ethanol, is structurally similar to pyruvate decarboxylases from other bacterial species.
Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3
Catherine N Leettola, Mary Knight, Duilio Cascio, Sigrid Hoffman, James U Bowie
BMC Structural Biology 2014, 14:17 (7 July 2014)
Structural characterization of the ANKS3-SAM/ANKS6-SAM complex reveals that a R823W point mutation causes destabilization of the SAM domain, a mechanism which is implicated in the pathogenesis of polycystic kidney disease.
High-resolution crystal structure of spin labelled (T21R1) azurin from
Pseudomonas aeruginosa: a challenging structural benchmark for in silico spin labelling algorithms
Nicole Florin, Olav Schiemann, Gregor Hagelueken
BMC Structural Biology 2014, 14:16 (29 May 2014)
Crystal packing of the spin labelled crystal structure of azurin provides a useful input model for evaluating two popular
in silico spin labelling programs, highlighting potential limitations of the algorithms.
High resolution structure of cleaved Serpin 42 Da from
Andrew M Ellisdon, Qingwei Zhang, Michelle A Henstridge, Travis K Johnson, Coral G Warr, Ruby HP Law, James C Whisstock
BMC Structural Biology 2014, 14:14 (24 April 2014)
Crystal structure of an engineered YopM-InlB hybrid protein
Dennis Breitsprecher, Ermanno Gherardi, Willem M Bleymüller, Hartmut H Niemann
BMC Structural Biology 2014, 14:12 (27 March 2014)
Structure-based protein engineering creates a hybrid protein of two bacterial virulence factors, the Yersinia enterocolitica type III secretion protein YopM and the Listeria mono-cytogenes invasion protein InB, to investigate MET signaling.
Structural insights into Noonan/LEOPARD syndrome-related mutants of protein-tyrosine phosphatase SHP2 (
Wei Qiu, Xiaonan Wang, Vladimir Romanov, Ashley Hutchinson, Andrés Lin, Maxim Ruzanov, Kevin P Battaile, Emil F Pai, Benjamin G Neel, Nickolay Y Chirgadze
BMC Structural Biology 2014, 14:10 (14 March 2014)