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	1. 1026 Accesses	Research article Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G Colten D Bracken, Amber M Neighbor, Kenneth K Lamlenn, Geoffrey C Thomas, Heidi L Schubert, Frank G Whitby, Bruce R Howard BMC Structural Biology 2011, 11:23 (10 May 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The archaebacterial isoform of malate synthase shares a beta 8/alpha 8 (TIM) barrel structure and a conserved catalytic mechanism with isoforms A and G, although it is found in trimer/hexamer equilibrium and displays N- and C-terminal truncations.
	2. 710 Accesses	Research article Thermostability in endoglucanases is fold-specific Ragothaman M Yennamalli, Andrew J Rader, Jeffrey D Wolt, Taner Z Sen BMC Structural Biology 2011, 11:10 (3 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	3. 709 Accesses	Research article Crystal structure of putative CbiT from Methanocaldococcus jannaschii: an intermediate enzyme activity in cobalamin (vitamin B₁₂) biosynthesis Balasundaram Padmanabhan, Shigeyuki Yokoyama, Yoshitaka Bessho BMC Structural Biology 2013, 13:10 (20 May 2013) Abstract \| Full text \| PDF \| PubMed
	4. 698 Accesses	Research article The role of hydrophobic interactions in positioning of peripheral proteins in membranes Andrei L Lomize, Irina D Pogozheva, Mikhail A Lomize, Henry I Mosberg BMC Structural Biology 2007, 7:44 (29 June 2007) Abstract \| Full text \| PDF \| PubMed
	5. 695 Accesses	Research article Mechanisms underlying dioxygen reduction in laccases. Structural and modelling studies focusing on proton transfer Isabel Bento, Catarina S Silva, Zhenjia Chen, Lígia O Martins, Peter F Lindley, Cláudio M Soares BMC Structural Biology 2010, 10:28 (7 September 2010) Abstract \| Full text \| PDF \| PubMed
	6. 672 Accesses	Research article The structure of pyogenecin immunity protein, a novel bacteriocin-like immunity protein from Streptococcus pyogenes Changsoo Chang, Penny Coggill, Alex Bateman, Robert D Finn, Marcin Cymborowski, Zbyszek Otwinowski, Wladek Minor, Lour Volkart, Andrzej Joachimiak BMC Structural Biology 2009, 9:75 (17 December 2009) Abstract \| Full text \| PDF \| PubMed
	7. 627 Accesses	Research article Prediction of protein-protein interactions in dengue virus coat proteins guided by low resolution cryoEM structures Rupali A Gadkari, Narayanaswamy Srinivasan BMC Structural Biology 2010, 10:17 (16 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	8. 626 Accesses	Research article Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domain Jane A Potter, Richard E Randall, Garry L Taylor BMC Structural Biology 2008, 8:11 (28 February 2008) Abstract \| Full text \| PDF \| PubMed
	9. 626 Accesses	Software LIGSITE^csc: predicting ligand binding sites using the Connolly surface and degree of conservation Bingding Huang, Michael Schroeder BMC Structural Biology 2006, 6:19 (24 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	10. 541 Accesses	Research article Types of inter-atomic interactions at the MHC-peptide interface: Identifying commonality from accumulated data Png Adrian, Ganapathy Rajaseger, Venkatarajan Mathura, Meena Sakharkar, Pandjassarame Kangueane BMC Structural Biology 2002, 2:2 (13 May 2002) Abstract \| Full text \| PDF \| PubMed
	11. 534 Accesses	Research article The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the β-clamp processivity factor Atif A Patoli, Jody A Winter, Karen A Bunting BMC Structural Biology 2013, 13:12 (4 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	12. 517 Accesses	Research article Molecular dynamics simulations on the Tre1 G protein-coupled receptor: exploring the role of the arginine of the NRY motif in Tre1 structure Margaret M Pruitt, Monica H Lamm, Clark R Coffman BMC Structural Biology 2013, 13:15 (18 September 2013) Abstract \| Full text \| PDF \| PubMed
	13. 503 Accesses	Research article The Ramachandran plots of glycine and pre-proline Bosco K Ho, Robert Brasseur BMC Structural Biology 2005, 5:14 (16 August 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	14. 392 Accesses	Research article Energetics of the protein-DNA-water interaction Francesca Spyrakis, Pietro Cozzini, Chiara Bertoli, Anna Marabotti, Glen E Kellogg, Andrea Mozzarelli BMC Structural Biology 2007, 7:4 (10 January 2007) Abstract \| Full text \| PDF \| PubMed
	15. 373 Accesses	Research article A structural role for the PHP domain in E. coli DNA polymerase III Tiago Barros, Joel Guenther, Brian Kelch, Jordan Anaya, Arjun Prabhakar, Mike O’Donnell, John Kuriyan, Meindert H Lamers BMC Structural Biology 2013, 13:8 (14 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Metal binding can be restored to E. coli polymerase III PHP domain with only three point mutations, demonstrating that the domain structure is highly conserved and is a major structural element of this bacterial replicative polymerase.
	16. 348 Accesses	Research article Structural insights into the substrate tunnel of Saccharomyces cerevisiae carbonic anhydrase Nce103 Yan-Bin Teng, Yong-Liang Jiang, Yong-Xing He, Wei-Wei He, Fu-Ming Lian, Yuxing Chen, Cong-Zhao Zhou BMC Structural Biology 2009, 9:67 (24 October 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17. 351 Accesses	Research article Crosslinking and mass spectrometry suggest that the isolated NTD domain dimer of Moloney murine leukemia virus integrase adopts a parallel arrangement in solution Daniel R Henriquez, Caifeng Zhao, Haiyan Zheng, José J Arbildua, Mónica L Acevedo, Monica J Roth, Oscar Leon BMC Structural Biology 2013, 13:14 (11 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	18. 337 Accesses	Research article Dependence of α-helical and β-sheet amino acid propensities on the overall protein fold type Kazuo Fujiwara, Hiromi Toda, Masamichi Ikeguchi BMC Structural Biology 2012, 12:18 (2 August 2012) Abstract \| Full text \| PDF \| PubMed
	19. 306 Accesses	Research article Antibody-protein interactions: benchmark datasets and prediction tools evaluation Julia V Ponomarenko, Philip E Bourne BMC Structural Biology 2007, 7:64 (2 October 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	20. 273 Accesses	Research article Structural and functional studies of S-adenosyl-L-methionine binding proteins: a ligand-centric approach Rajaram Gana, Shruti Rao, Hongzhan Huang, Cathy Wu, Sona Vasudevan BMC Structural Biology 2013, 13:6 (25 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A new systematic approach for grouping protein structures based upon the type and conformation of the ligand they bind to reveals some unexpected findings and extends the existing structural classification of S-adenosyl-L-13 methionine (SAM) binding proteins
	21. 266 Accesses	Research article Natural history of S-adenosylmethionine-binding proteins Piotr Z Kozbial, Arcady R Mushegian BMC Structural Biology 2005, 5:19 (14 October 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Analysis of the phyletic distribution and structural similarities of S-adenosylmethionine-binding proteins indicate that two widespread folds, the Rossman fold and TIM barrel, have repeatedly evolved for diverse types of reactions that require S-adenosylmethionine.
	22. 231 Accesses	Research article Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment Joanne E Nettleship, Jingshan Ren, David J Scott, Nahid Rahman, Deborah Hatherley, Yuguang Zhao, David I Stuart, A Barclay, Raymond J Owens BMC Structural Biology 2013, 13:13 (4 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Crystallisation of signal regulatory protein SIRPgamma complexed with the Fab fragment of the OX117 antibody reveals conservation of binding domains between members of the SIRP family and dimerization specific to the crystal structure.
	23. 229 Accesses	Research article Statistical analysis of the Bacterial Carbohydrate Structure Data Base (BCSDB): Characteristics and diversity of bacterial carbohydrates in comparison with mammalian glycans Stephan Herget, Philip V Toukach, René Ranzinger, William E Hull, Yuriy A Knirel, Claus-Wilhelm von der Lieth BMC Structural Biology 2008, 8:35 (11 August 2008) Abstract \| Full text \| PDF \| PubMed
	24. 220 Accesses	Research article Crystal structural analysis of human serum albumin complexed with hemin and fatty acid Patricia A Zunszain, Jamie Ghuman, Teruyuki Komatsu, Eishun Tsuchida, Stephen Curry BMC Structural Biology 2003, 3:6 (7 July 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The structure of a human serum albumin-hemin-myristate complex reveals a new conformation plus key polar and hydrophobic interactions that should be useful in designing HSA-heme complexes with modified oxygen-binding properties.
	25. 204 Accesses	Software K2D2: Estimation of protein secondary structure from circular dichroism spectra Carolina Perez-Iratxeta, Miguel A Andrade-Navarro BMC Structural Biology 2008, 8:25 (13 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Predicting the secondary structure of proteins can be facilitated by the K2D2 method, which compares circular dichroism (CD) spectra of unknown protein structures to a self-organizing map of CD spectra for known structures.