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		Research article Conservation and divergence between cytoplasmic and muscle-specific actin capping proteins: insights from the crystal structure of cytoplasmic Cap32/34 from Dictyostelium discoideum Christian Eckert, Agnieszka Goretzki, Maria Faberova, Martin Kollmar BMC Structural Biology 2012, 12:12 (1 June 2012) Abstract \| Provisional PDF
		Research article Functional region prediction with a set of appropriate homologous sequences-an index for sequence selection by integrating structure and sequence information with spatial statistics Wataru Nemoto, Hiroyuki Toh BMC Structural Biology 2012, 12:11 (29 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Modeling holo-ACP:DH and holo-ACP:KR complexes of modular polyketide synthases: a docking and molecular dynamics study Swadha Anand, Debasisa Mohanty BMC Structural Biology 2012, 12:10 (28 May 2012) Abstract \| Provisional PDF \| PubMed
		Commentary Reliable structural interpretation of small-angle scattering data from bio-molecules in solution - the importance of quality control and a standard reporting framework David A Jacques, Jules M Guss, Jill Trewhella BMC Structural Biology 2012, 12:9 (17 May 2012) Abstract \| Provisional PDF \| PubMed \| 1 comment \| Editor’s summary Jill Trewhella and colleagues describe the rationale behind guidelines recently issued by The International Union of Crystallography for the reporting of biomolecular structures derived from Small-Angle Scattering (SAS) data.
		Research article Are different stoichiometries feasible for complexes between lymphotoxin-alpha and tumor necrosis factor receptor 1? Nahren M Mascarenhas, Johannes Kästner BMC Structural Biology 2012, 12:8 (8 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking sub-site C6 Lalitha Venkatramani, Eric S Johnson, Gundarao Kolavi, Gillian M Air, Wayne J Brouillette, Blaine HM Mooers BMC Structural Biology 2012, 12:7 (6 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary The crystal structure of a novel benzoic acid inhibitor of influenza neuraminidase reveals an increased number of contacts compared to previous inhibitors, due to a tilt in the position of the benzene ring that maximizes these interactions.
		Research article Comparison of tertiary structures of proteins in protein-protein complexes with unbound forms suggests prevalence of allostery in signalling proteins Lakshmipuram S Swapna, Swapnil Mahajan, Alexandre de Brevern, Narayanaswamy Srinivasan BMC Structural Biology 2012, 12:6 (3 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Exploring functionally related enzymes using radially distributed properties of active sites around the reacting points of bound ligands Keisuke Ueno, Katsuhiko Mineta, Kimihito Ito, Toshinori Endo BMC Structural Biology 2012, 12:5 (26 April 2012) Abstract \| Provisional PDF \| PubMed
		Correction Correction: Prediction and analysis of the modular structure of cytochrome P450 monooxygenases Demet Sirim, Michael Widmann, Florian Wagner, Jurgen Pleiss BMC Structural Biology 2012, 12:4 (25 April 2012) Abstract \| Provisional PDF \| PubMed
		Research article A structural model of the E. coli PhoB Dimer in the transcription initiation complex Chang-Shung Tung, Benjamin H McMahon BMC Structural Biology 2012, 12:3 (20 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Crystal structures from the Plasmodium peroxiredoxins: new insights into oligomerization and product binding Wei Qiu, Aiping Dong, Juan C Pizarro, Alexei Botchkarsev, Jinrong Min, Amy K Wernimont, Tanya Hills, Raymond Hui, Jennifer D Artz BMC Structural Biology 2012, 12:2 (19 March 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Structural characterization of peroxiredoxins from Plasmodium species identifies the novel toroid octameric oligomer of PyTrx-Px1 and confirms that PvTrx-Px1 is a hydrogen peroxide-sensitive peroxiredoxin, which may aid targeting of these antioxidant enzymes in drug design
		Research article A transcriptional-switch model for Slr1738-controlled gene expression in the cyanobacterium Synechocystis Paul Garcin, Olivier Delalande, Ju-Yuan Zhang, Corinne Cassier-Chauvat, Franck Chauvat, Yves Boulard BMC Structural Biology 2012, 12:1 (30 January 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A 3D structure of the complex between the PerR-like regulator Slr1738 and its target DNA, which controls metal and oxidative stress response in the cyanobaterium Synechocystis, provides insight into stability and recognition in protein-DNA interactions
		Research article Structural adaptation of extreme halophilic proteins through decrease of conserved hydrophobic contact surface Alessandro Siglioccolo, Alessandro Paiardini, Maria Piscitelli, Stefano Pascarella BMC Structural Biology 2011, 11:50 (22 December 2011) Abstract \| Full text \| PDF \| PubMed
		Research article The Host-Pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains Sara MØ Solbak, Victor Wray, Ole Horvli, Arnt J Raae, Marte I Flydal, Petra Henklein, Peter Henklein, Manfred Nimtz, Ulrich Schubert, Torgils Fossen BMC Structural Biology 2011, 11:49 (20 December 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Identification of a region of HIV-1 Vpr which binds specifically to the host cellular factor CypA with similar affinity to full-length Vpr is the first such binding domain described that involves no proline residues.
		Research article Structural comparison of tRNA m¹A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions Amandine Guelorget, Pierre Barraud, Carine Tisné, Béatrice Golinelli-Pimpaneau BMC Structural Biology 2011, 11:48 (14 December 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosis RS Anand, Sulochana Somasundaram, Mukesh Doble, CN Paramasivan BMC Structural Biology 2011, 11:47 (12 December 2011) Abstract \| Full text \| PDF \| PubMed
		Methodology article The redundancy of NMR restraints can be used to accelerate the unfolding behavior of an SH3 domain during molecular dynamics simulations Nathalie Duclert-Savatier, Leandro Martínez, Michael Nilges, Thérèse E Malliavin BMC Structural Biology 2011, 11:46 (24 November 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Benchmarks for flexible and rigid transcription factor-DNA docking RyangGuk Kim, Rosario I Corona, Bo Hong, Jun-tao Guo BMC Structural Biology 2011, 11:45 (1 November 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Hydration studies on the archaeal protein Sso7d using NMR measurements and MD simulations Andrea Bernini, Ottavia Spiga, Roberto Consonni, Ivana Arosio, Paola Fusi, Simone Cirri, Annamaria Guagliardi, Neri Niccolai BMC Structural Biology 2011, 11:44 (21 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Computational analysis of a novel mutation in ETFDH gene highlights its long-range effects on the FAD-binding motif Tze-Kiong Er, Chih-Chieh Chen, Yen-Yi Liu, Hui-Chiu Chang, Yin-Hsiu Chien, Jan-Gowth Chang, Jenn-Kang Hwang, Yuh-Jyh Jong BMC Structural Biology 2011, 11:43 (21 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Comparative void-volume analysis of psychrophilic and mesophilic enzymes: Structural bioinformatics of psychrophilic enzymes reveals sources of core flexibility Diana I Paredes, Kyle Watters, Derek J Pitman, Christopher Bystroff, Jonathan S Dordick BMC Structural Biology 2011, 11:42 (20 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Hydration sites of unpaired RNA bases: a statistical analysis of the PDB structures Svetlana Kirillova, Oliviero Carugo BMC Structural Biology 2011, 11:41 (19 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Central domain deletions affect the SAXS solution structure and function of Yeast Hsp40 proteins Sis1 and Ydj1 Julio C Silva, Julio C Borges, Douglas M Cyr, Carlos HI Ramos, Iris L Torriani BMC Structural Biology 2011, 11:40 (19 October 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Deletion of the central ZFLR-CTDI domain in the Hsp40 protein Ydj1 changes the relative position of the J-domain, suggesting that interactions between these domains are important in determining the unique quaternary structure of Type I Hsp40s
		Research article Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis Thomas E Edwards, Ariel B Abramov, Eric R Smith, Ruth O Baydo, Jess T Leonard, David J Leibly, Kaitlin B Thompkins, Matthew C Clifton, Anna S Gardberg, Bart L Staker, Wesley C Van Voorhis, Peter J Myler, Lance J Stewart BMC Structural Biology 2011, 11:39 (13 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research article A conformation ensemble approach to protein residue-residue contact Jesse Eickholt, Zheng Wang, Jianlin Cheng BMC Structural Biology 2011, 11:38 (12 October 2011) Abstract \| Full text \| PDF \| PubMed

	All
		Research article Conservation and divergence between cytoplasmic and muscle-specific actin capping proteins: insights from the crystal structure of cytoplasmic Cap32/34 from Dictyostelium discoideum Christian Eckert, Agnieszka Goretzki, Maria Faberova, Martin Kollmar BMC Structural Biology 2012, 12:12 (1 June 2012) Abstract \| Provisional PDF
		Research article Functional region prediction with a set of appropriate homologous sequences-an index for sequence selection by integrating structure and sequence information with spatial statistics Wataru Nemoto, Hiroyuki Toh BMC Structural Biology 2012, 12:11 (29 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Modeling holo-ACP:DH and holo-ACP:KR complexes of modular polyketide synthases: a docking and molecular dynamics study Swadha Anand, Debasisa Mohanty BMC Structural Biology 2012, 12:10 (28 May 2012) Abstract \| Provisional PDF \| PubMed
		Commentary Reliable structural interpretation of small-angle scattering data from bio-molecules in solution - the importance of quality control and a standard reporting framework David A Jacques, Jules M Guss, Jill Trewhella BMC Structural Biology 2012, 12:9 (17 May 2012) Abstract \| Provisional PDF \| PubMed \| 1 comment \| Editor’s summary Jill Trewhella and colleagues describe the rationale behind guidelines recently issued by The International Union of Crystallography for the reporting of biomolecular structures derived from Small-Angle Scattering (SAS) data.
		Research article Are different stoichiometries feasible for complexes between lymphotoxin-alpha and tumor necrosis factor receptor 1? Nahren M Mascarenhas, Johannes Kästner BMC Structural Biology 2012, 12:8 (8 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking sub-site C6 Lalitha Venkatramani, Eric S Johnson, Gundarao Kolavi, Gillian M Air, Wayne J Brouillette, Blaine HM Mooers BMC Structural Biology 2012, 12:7 (6 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary The crystal structure of a novel benzoic acid inhibitor of influenza neuraminidase reveals an increased number of contacts compared to previous inhibitors, due to a tilt in the position of the benzene ring that maximizes these interactions.
		Research article Comparison of tertiary structures of proteins in protein-protein complexes with unbound forms suggests prevalence of allostery in signalling proteins Lakshmipuram S Swapna, Swapnil Mahajan, Alexandre de Brevern, Narayanaswamy Srinivasan BMC Structural Biology 2012, 12:6 (3 May 2012) Abstract \| Provisional PDF \| PubMed
		Research article Exploring functionally related enzymes using radially distributed properties of active sites around the reacting points of bound ligands Keisuke Ueno, Katsuhiko Mineta, Kimihito Ito, Toshinori Endo BMC Structural Biology 2012, 12:5 (26 April 2012) Abstract \| Provisional PDF \| PubMed
		Correction Correction: Prediction and analysis of the modular structure of cytochrome P450 monooxygenases Demet Sirim, Michael Widmann, Florian Wagner, Jurgen Pleiss BMC Structural Biology 2012, 12:4 (25 April 2012) Abstract \| Provisional PDF \| PubMed
		Research article A structural model of the E. coli PhoB Dimer in the transcription initiation complex Chang-Shung Tung, Benjamin H McMahon BMC Structural Biology 2012, 12:3 (20 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Crystal structures from the Plasmodium peroxiredoxins: new insights into oligomerization and product binding Wei Qiu, Aiping Dong, Juan C Pizarro, Alexei Botchkarsev, Jinrong Min, Amy K Wernimont, Tanya Hills, Raymond Hui, Jennifer D Artz BMC Structural Biology 2012, 12:2 (19 March 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Structural characterization of peroxiredoxins from Plasmodium species identifies the novel toroid octameric oligomer of PyTrx-Px1 and confirms that PvTrx-Px1 is a hydrogen peroxide-sensitive peroxiredoxin, which may aid targeting of these antioxidant enzymes in drug design
		Research article A transcriptional-switch model for Slr1738-controlled gene expression in the cyanobacterium Synechocystis Paul Garcin, Olivier Delalande, Ju-Yuan Zhang, Corinne Cassier-Chauvat, Franck Chauvat, Yves Boulard BMC Structural Biology 2012, 12:1 (30 January 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A 3D structure of the complex between the PerR-like regulator Slr1738 and its target DNA, which controls metal and oxidative stress response in the cyanobaterium Synechocystis, provides insight into stability and recognition in protein-DNA interactions
		Research article Structural adaptation of extreme halophilic proteins through decrease of conserved hydrophobic contact surface Alessandro Siglioccolo, Alessandro Paiardini, Maria Piscitelli, Stefano Pascarella BMC Structural Biology 2011, 11:50 (22 December 2011) Abstract \| Full text \| PDF \| PubMed
		Research article The Host-Pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains Sara MØ Solbak, Victor Wray, Ole Horvli, Arnt J Raae, Marte I Flydal, Petra Henklein, Peter Henklein, Manfred Nimtz, Ulrich Schubert, Torgils Fossen BMC Structural Biology 2011, 11:49 (20 December 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Identification of a region of HIV-1 Vpr which binds specifically to the host cellular factor CypA with similar affinity to full-length Vpr is the first such binding domain described that involves no proline residues.
		Research article Structural comparison of tRNA m¹A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions Amandine Guelorget, Pierre Barraud, Carine Tisné, Béatrice Golinelli-Pimpaneau BMC Structural Biology 2011, 11:48 (14 December 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosis RS Anand, Sulochana Somasundaram, Mukesh Doble, CN Paramasivan BMC Structural Biology 2011, 11:47 (12 December 2011) Abstract \| Full text \| PDF \| PubMed
		Methodology article The redundancy of NMR restraints can be used to accelerate the unfolding behavior of an SH3 domain during molecular dynamics simulations Nathalie Duclert-Savatier, Leandro Martínez, Michael Nilges, Thérèse E Malliavin BMC Structural Biology 2011, 11:46 (24 November 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Benchmarks for flexible and rigid transcription factor-DNA docking RyangGuk Kim, Rosario I Corona, Bo Hong, Jun-tao Guo BMC Structural Biology 2011, 11:45 (1 November 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Hydration studies on the archaeal protein Sso7d using NMR measurements and MD simulations Andrea Bernini, Ottavia Spiga, Roberto Consonni, Ivana Arosio, Paola Fusi, Simone Cirri, Annamaria Guagliardi, Neri Niccolai BMC Structural Biology 2011, 11:44 (21 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Computational analysis of a novel mutation in ETFDH gene highlights its long-range effects on the FAD-binding motif Tze-Kiong Er, Chih-Chieh Chen, Yen-Yi Liu, Hui-Chiu Chang, Yin-Hsiu Chien, Jan-Gowth Chang, Jenn-Kang Hwang, Yuh-Jyh Jong BMC Structural Biology 2011, 11:43 (21 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Comparative void-volume analysis of psychrophilic and mesophilic enzymes: Structural bioinformatics of psychrophilic enzymes reveals sources of core flexibility Diana I Paredes, Kyle Watters, Derek J Pitman, Christopher Bystroff, Jonathan S Dordick BMC Structural Biology 2011, 11:42 (20 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Hydration sites of unpaired RNA bases: a statistical analysis of the PDB structures Svetlana Kirillova, Oliviero Carugo BMC Structural Biology 2011, 11:41 (19 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Central domain deletions affect the SAXS solution structure and function of Yeast Hsp40 proteins Sis1 and Ydj1 Julio C Silva, Julio C Borges, Douglas M Cyr, Carlos HI Ramos, Iris L Torriani BMC Structural Biology 2011, 11:40 (19 October 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Deletion of the central ZFLR-CTDI domain in the Hsp40 protein Ydj1 changes the relative position of the J-domain, suggesting that interactions between these domains are important in determining the unique quaternary structure of Type I Hsp40s
		Research article Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis Thomas E Edwards, Ariel B Abramov, Eric R Smith, Ruth O Baydo, Jess T Leonard, David J Leibly, Kaitlin B Thompkins, Matthew C Clifton, Anna S Gardberg, Bart L Staker, Wesley C Van Voorhis, Peter J Myler, Lance J Stewart BMC Structural Biology 2011, 11:39 (13 October 2011) Abstract \| Full text \| PDF \| PubMed
		Research article A conformation ensemble approach to protein residue-residue contact Jesse Eickholt, Zheng Wang, Jianlin Cheng BMC Structural Biology 2011, 11:38 (12 October 2011) Abstract \| Full text \| PDF \| PubMed