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		Research article Short tandem repeats in the inhibitory domain of the mineralocorticoid receptor: prediction of a beta-solenoid structure Metaxia Vlassi, Katharina Brauns, Miguel A Andrade-Navarro BMC Structural Biology 2013, 13:17 (2 October 2013) Abstract \| Provisional PDF
		Research article Detection of persistent organic pollutants binding modes with androgen receptor ligand binding domain by docking and molecular dynamics Xian Xu, Ji Su, Anna Bizzarri, Salvatore Cannistraro, Ming Liu, Yi Zeng, Wei Chen, Cun Wang BMC Structural Biology 2013, 13:16 (22 September 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Molecular dynamics simulations on the Tre1 G protein-coupled receptor: exploring the role of the arginine of the NRY motif in Tre1 structure Margaret M Pruitt, Monica H Lamm, Clark R Coffman BMC Structural Biology 2013, 13:15 (18 September 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Crosslinking and mass spectrometry suggest that the isolated NTD domain dimer of Moloney murine leukemia virus integrase adopts a parallel arrangement in solution Daniel R Henriquez, Caifeng Zhao, Haiyan Zheng, José J Arbildua, Mónica L Acevedo, Monica J Roth, Oscar Leon BMC Structural Biology 2013, 13:14 (11 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment Joanne E Nettleship, Jingshan Ren, David J Scott, Nahid Rahman, Deborah Hatherley, Yuguang Zhao, David I Stuart, A Barclay, Raymond J Owens BMC Structural Biology 2013, 13:13 (4 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Crystallisation of signal regulatory protein SIRPgamma complexed with the Fab fragment of the OX117 antibody reveals conservation of binding domains between members of the SIRP family and dimerization specific to the crystal structure.
		Research article The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the β-clamp processivity factor Atif A Patoli, Jody A Winter, Karen A Bunting BMC Structural Biology 2013, 13:12 (4 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article Crystal structure of the C-terminal globular domain of the third paralog of the Archaeoglobus fulgidus oligosaccharyltransferases Shunsuke Matsumoto, Atsushi Shimada, Daisuke Kohda BMC Structural Biology 2013, 13:11 (1 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article Crystal structure of putative CbiT from Methanocaldococcus jannaschii: an intermediate enzyme activity in cobalamin (vitamin B₁₂) biosynthesis Balasundaram Padmanabhan, Shigeyuki Yokoyama, Yoshitaka Bessho BMC Structural Biology 2013, 13:10 (20 May 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Helical ambivalency induced by point mutations Nicholus Bhattacharjee, Parbati Biswas BMC Structural Biology 2013, 13:9 (15 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article A structural role for the PHP domain in E. coli DNA polymerase III Tiago Barros, Joel Guenther, Brian Kelch, Jordan Anaya, Arjun Prabhakar, Mike O’Donnell, John Kuriyan, Meindert H Lamers BMC Structural Biology 2013, 13:8 (14 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Metal binding can be restored to E. coli polymerase III PHP domain with only three point mutations, demonstrating that the domain structure is highly conserved and is a major structural element of this bacterial replicative polymerase.
		Research article Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2′-deoxyuridine-5′-monophosphate on ABCC11 in silico models Mylène Honorat, Raphaël Terreux, Pierre Falson, Attilio Di Pietro, Charles Dumontet, Lea Payen BMC Structural Biology 2013, 13:7 (6 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article Structural and functional studies of S-adenosyl-L-methionine binding proteins: a ligand-centric approach Rajaram Gana, Shruti Rao, Hongzhan Huang, Cathy Wu, Sona Vasudevan BMC Structural Biology 2013, 13:6 (25 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A new systematic approach for grouping protein structures based upon the type and conformation of the ligand they bind to reveals some unexpected findings and extends the existing structural classification of S-adenosyl-L-13 methionine (SAM) binding proteins
		Research article Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC Jungwook Kim, Steven C Almo BMC Structural Biology 2013, 13:5 (24 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article Disturbance of DNA conformation by the binding of testosterone-based platinum drugs via groove-face and intercalative interactions: a molecular dynamics simulation study Shanshan Cui, Yan Wang, Guangju Chen BMC Structural Biology 2013, 13:4 (22 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article The role of Cysteine 6.47 in class A GPCRs Mireia Olivella, Gianluigi Caltabiano, Arnau Cordomí BMC Structural Biology 2013, 13:3 (15 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Analysis of G protein-coupled receptor (GPCR) crystal structures and molecular dynamics simulations of model peptides suggests Cys6.47 is the gate keeper of a hydrogen bond network involving residues known to be crucial to receptor activation.
		Research article Designing and benchmarking the MULTICOM protein structure prediction system Jilong Li, Xin Deng, Jesse Eickholt, Jianlin Cheng BMC Structural Biology 2013, 13:2 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
		Reviewer acknowledgement Annual acknowledgement of manuscript reviewers Simon Harold BMC Structural Biology 2013, 13:1 (19 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them Volodymyr O Kitam, Oksana V Maksymchuk, Mykola O Chashchyn BMC Structural Biology 2012, 12:33 (17 December 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme’s active site closure Jaeok Park, Yih-Shyan Lin, Joris W De Schutter, Youla S Tsantrizos, Albert M Berghuis BMC Structural Biology 2012, 12:32 (12 December 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Three crystal structures of human farnesyl pyrophosphate synthase (FPPS) in ternary complex with a novel bisphosphonate inhibitor reveal mechanistic insight of the conformational change in the C-terminal tail closure that is essential for catalysis.
		Software Protein Nano-Object Integrator (ProNOI) for generating atomic style objects for molecular modeling Nicholas Smith, Brandon Campbell, Lin Li, Chuan Li, Emil Alexov BMC Structural Biology 2012, 12:31 (5 December 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Protein Nano-Object Integrator (ProNOI) is a novel software tool for generating atomic-style nano shapes in conjunction with biological macromolecules, allowing users to manipulate shape, dimension and position, and charge objects with user-specified charge density.
		Research article Theoretical investigation on structural, functional and epitope of a 12 kDa excretory-secretory protein from Toxoplasma gondii Yap Boon Wooi Tommy, Theam Soon Lim, Rahmah Noordin, Geita Saadatnia, Yee Siew Choong BMC Structural Biology 2012, 12:30 (27 November 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The 3D structure of the 12 kDa excretory-secretory protein of Toxoplasma gondii reveals a thioredoxin-like backbone and three potential epitopes functioning as a single antibody binding site, aiding the development of an antigen detection test for toxoplasmosis.
		Methodology article MTMDAT-HADDOCK: High-throughput, protein complex structure modeling based on limited proteolysis and mass spectrometry Janosch Hennig, Sjoerd J de Vries, Klaus DM Hennig, Leah Randles, Kylie J Walters, Maria Sunnerhagen, Alexandre MJJ Bonvin BMC Structural Biology 2012, 12:29 (15 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Structural and molecular basis of interaction of HCV non-structural protein 5A with human casein kinase 1α and PKR Govindarajan Sudha, Subburaj Yamunadevi, Nidhi Tyagi, Saumitra Das, Narayanaswamy Srinivasan BMC Structural Biology 2012, 12:28 (13 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Evolutionarily consistent families in SCOP: sequence, structure and function Ralph B Pethica, Michael Levitt, Julian Gough BMC Structural Biology 2012, 12:27 (18 October 2012) Abstract \| Full text \| PDF \| PubMed
		Software Structure Motivator: A tool for exploring small three-dimensional elements in proteins David P Leader, E Milner-White BMC Structural Biology 2012, 12:26 (16 October 2012) Abstract \| Full text \| PDF \| PubMed

	All
		Research article Short tandem repeats in the inhibitory domain of the mineralocorticoid receptor: prediction of a beta-solenoid structure Metaxia Vlassi, Katharina Brauns, Miguel A Andrade-Navarro BMC Structural Biology 2013, 13:17 (2 October 2013) Abstract \| Provisional PDF
		Research article Detection of persistent organic pollutants binding modes with androgen receptor ligand binding domain by docking and molecular dynamics Xian Xu, Ji Su, Anna Bizzarri, Salvatore Cannistraro, Ming Liu, Yi Zeng, Wei Chen, Cun Wang BMC Structural Biology 2013, 13:16 (22 September 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Molecular dynamics simulations on the Tre1 G protein-coupled receptor: exploring the role of the arginine of the NRY motif in Tre1 structure Margaret M Pruitt, Monica H Lamm, Clark R Coffman BMC Structural Biology 2013, 13:15 (18 September 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Crosslinking and mass spectrometry suggest that the isolated NTD domain dimer of Moloney murine leukemia virus integrase adopts a parallel arrangement in solution Daniel R Henriquez, Caifeng Zhao, Haiyan Zheng, José J Arbildua, Mónica L Acevedo, Monica J Roth, Oscar Leon BMC Structural Biology 2013, 13:14 (11 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment Joanne E Nettleship, Jingshan Ren, David J Scott, Nahid Rahman, Deborah Hatherley, Yuguang Zhao, David I Stuart, A Barclay, Raymond J Owens BMC Structural Biology 2013, 13:13 (4 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Crystallisation of signal regulatory protein SIRPgamma complexed with the Fab fragment of the OX117 antibody reveals conservation of binding domains between members of the SIRP family and dimerization specific to the crystal structure.
		Research article The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the β-clamp processivity factor Atif A Patoli, Jody A Winter, Karen A Bunting BMC Structural Biology 2013, 13:12 (4 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article Crystal structure of the C-terminal globular domain of the third paralog of the Archaeoglobus fulgidus oligosaccharyltransferases Shunsuke Matsumoto, Atsushi Shimada, Daisuke Kohda BMC Structural Biology 2013, 13:11 (1 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article Crystal structure of putative CbiT from Methanocaldococcus jannaschii: an intermediate enzyme activity in cobalamin (vitamin B₁₂) biosynthesis Balasundaram Padmanabhan, Shigeyuki Yokoyama, Yoshitaka Bessho BMC Structural Biology 2013, 13:10 (20 May 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Helical ambivalency induced by point mutations Nicholus Bhattacharjee, Parbati Biswas BMC Structural Biology 2013, 13:9 (15 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article A structural role for the PHP domain in E. coli DNA polymerase III Tiago Barros, Joel Guenther, Brian Kelch, Jordan Anaya, Arjun Prabhakar, Mike O’Donnell, John Kuriyan, Meindert H Lamers BMC Structural Biology 2013, 13:8 (14 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Metal binding can be restored to E. coli polymerase III PHP domain with only three point mutations, demonstrating that the domain structure is highly conserved and is a major structural element of this bacterial replicative polymerase.
		Research article Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2′-deoxyuridine-5′-monophosphate on ABCC11 in silico models Mylène Honorat, Raphaël Terreux, Pierre Falson, Attilio Di Pietro, Charles Dumontet, Lea Payen BMC Structural Biology 2013, 13:7 (6 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article Structural and functional studies of S-adenosyl-L-methionine binding proteins: a ligand-centric approach Rajaram Gana, Shruti Rao, Hongzhan Huang, Cathy Wu, Sona Vasudevan BMC Structural Biology 2013, 13:6 (25 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary A new systematic approach for grouping protein structures based upon the type and conformation of the ligand they bind to reveals some unexpected findings and extends the existing structural classification of S-adenosyl-L-13 methionine (SAM) binding proteins
		Research article Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC Jungwook Kim, Steven C Almo BMC Structural Biology 2013, 13:5 (24 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article Disturbance of DNA conformation by the binding of testosterone-based platinum drugs via groove-face and intercalative interactions: a molecular dynamics simulation study Shanshan Cui, Yan Wang, Guangju Chen BMC Structural Biology 2013, 13:4 (22 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
		Research article The role of Cysteine 6.47 in class A GPCRs Mireia Olivella, Gianluigi Caltabiano, Arnau Cordomí BMC Structural Biology 2013, 13:3 (15 March 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Analysis of G protein-coupled receptor (GPCR) crystal structures and molecular dynamics simulations of model peptides suggests Cys6.47 is the gate keeper of a hydrogen bond network involving residues known to be crucial to receptor activation.
		Research article Designing and benchmarking the MULTICOM protein structure prediction system Jilong Li, Xin Deng, Jesse Eickholt, Jianlin Cheng BMC Structural Biology 2013, 13:2 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
		Reviewer acknowledgement Annual acknowledgement of manuscript reviewers Simon Harold BMC Structural Biology 2013, 13:1 (19 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them Volodymyr O Kitam, Oksana V Maksymchuk, Mykola O Chashchyn BMC Structural Biology 2012, 12:33 (17 December 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme’s active site closure Jaeok Park, Yih-Shyan Lin, Joris W De Schutter, Youla S Tsantrizos, Albert M Berghuis BMC Structural Biology 2012, 12:32 (12 December 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Three crystal structures of human farnesyl pyrophosphate synthase (FPPS) in ternary complex with a novel bisphosphonate inhibitor reveal mechanistic insight of the conformational change in the C-terminal tail closure that is essential for catalysis.
		Software Protein Nano-Object Integrator (ProNOI) for generating atomic style objects for molecular modeling Nicholas Smith, Brandon Campbell, Lin Li, Chuan Li, Emil Alexov BMC Structural Biology 2012, 12:31 (5 December 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Protein Nano-Object Integrator (ProNOI) is a novel software tool for generating atomic-style nano shapes in conjunction with biological macromolecules, allowing users to manipulate shape, dimension and position, and charge objects with user-specified charge density.
		Research article Theoretical investigation on structural, functional and epitope of a 12 kDa excretory-secretory protein from Toxoplasma gondii Yap Boon Wooi Tommy, Theam Soon Lim, Rahmah Noordin, Geita Saadatnia, Yee Siew Choong BMC Structural Biology 2012, 12:30 (27 November 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The 3D structure of the 12 kDa excretory-secretory protein of Toxoplasma gondii reveals a thioredoxin-like backbone and three potential epitopes functioning as a single antibody binding site, aiding the development of an antigen detection test for toxoplasmosis.
		Methodology article MTMDAT-HADDOCK: High-throughput, protein complex structure modeling based on limited proteolysis and mass spectrometry Janosch Hennig, Sjoerd J de Vries, Klaus DM Hennig, Leah Randles, Kylie J Walters, Maria Sunnerhagen, Alexandre MJJ Bonvin BMC Structural Biology 2012, 12:29 (15 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Structural and molecular basis of interaction of HCV non-structural protein 5A with human casein kinase 1α and PKR Govindarajan Sudha, Subburaj Yamunadevi, Nidhi Tyagi, Saumitra Das, Narayanaswamy Srinivasan BMC Structural Biology 2012, 12:28 (13 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Evolutionarily consistent families in SCOP: sequence, structure and function Ralph B Pethica, Michael Levitt, Julian Gough BMC Structural Biology 2012, 12:27 (18 October 2012) Abstract \| Full text \| PDF \| PubMed
		Software Structure Motivator: A tool for exploring small three-dimensional elements in proteins David P Leader, E Milner-White BMC Structural Biology 2012, 12:26 (16 October 2012) Abstract \| Full text \| PDF \| PubMed