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Physiological genomics Section edited by Ricardo Saban

This section aims to publish studies looking at the relationship of genes to complex physiological functions in both human and model systems. The section encourages the submission of experimental and computational studies linking genes and pathways to physiological functions including systems biology approaches.

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Research article   Open Access Highly Accessed

Dynamically regulated miRNA-mRNA networks revealed by exercise

Alexander G Tonevitsky, Diana V Maltseva, Asghar Abbasi, Timur R Samatov, Dmitry A Sakharov, Maxim U Shkurnikov, Alexey E Lebedev, Vladimir V Galatenko, Anatoly I Grigoriev, Hinnak Northoff BMC Physiology 2013, 13:9 (7 June 2013)

Abstract | Full text | PDF | ePUB |  Editor’s summary

Transcriptional changes of mRNAs in athletes undergoing moderate exercise, followed by a recovery period, reveals miRNA-mRNA networks dynamically regulated during this process and provides insight into the regulatory role of these molecules in stress adaptation.

2.

Research article   Open Access

Genomic homeostasis is dysregulated in favour of apoptosis in the colonic epithelium of the azoxymethane treated rat

Caroline A Kerr, Barney M Hines, Janet M Shaw, Robert Dunne, Lauren M Bragg, Julie Clarke, Trevor Lockett, Richard Head BMC Physiology 2013, 13:2 (23 January 2013)

Abstract | Full text | PDF | PubMed

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