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Mechanisms of pressure-diuresis and pressure-natriuresis in Dahl salt-resistant and Dahl salt-sensitive rats
Daniel A Beard, Muriel Mescam BMC Physiology 2012, 12:6 (14 May 2012)
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Contractile Properties and Movement Behaviour in Neonatal Rats with Axotomy, treated with the NMDA Antagonist DAP5
Konstantinos Petsanis, Athanasios Chatzisotiriou, Dorothea Kapoukranidou, Constantina Simeonidou, Dimitrios Kouvelas, Maria Albani BMC Physiology 2012, 12:5 (2 May 2012)
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Editor’s summary
Systemic administration of the NMDA antagonist DAP5 has positive effects on recovery of muscle contractile properties and motor behavior after sciatic nerve crush in neonatal rats and may have therapeutic potential in other models of excitotoxic injury.
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Obesity-associated insulin resistance is correlated to adipose tissue vascular endothelial growth factors and metalloproteinase levels
Francisco JOSE Tinahones, Leticia Coin-Araguez, Maria DOLORES Mayas, Eduardo Garcia-Fuentes, Carmen HURTADO Del Pozo, Joan Vendrell, Fernando Cardona, Rosa MARIA Calvo, Maria JESUS Obregon, Rajaa El Bekay BMC Physiology 2012, 12:4 (2 April 2012)
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Small molecule screening platform for assessment of cardiovascular toxicity on adult zebrafish heart
Satish Kitambi, Erik S Nilsson, Petra Sekyrova, Cristian Ibarra, Gilbert Tekeoh, Michael Andäng, Patrik Ernfors, Per Uhlén BMC Physiology 2012, 12:3 (26 March 2012)
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Editor’s summary
Zebrafish hearts can be used for screening the cardiovascular toxicity of small molecules in a new sensitive and reliable method that allows a variety of readouts, such as expression of biomarkers.
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Matrix metalloproteinases 2 and 9 increase permeability of sheep pleura in vitro
Eleni Apostolidou, Efrosyni Paraskeva, Konstantinos Gourgoulianis, Paschalis-Adam Molyvdas, Chrissi Hatzoglou BMC Physiology 2012, 12:2 (16 March 2012)
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Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion
Jennifer A Sanders, Christoph Schorl, Ajay Patel, John M Sedivy, Philip A Gruppuso BMC Physiology 2012, 12:1 (7 March 2012)
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HOXA4 protein levels and localization in the aorta and in human abdominal aortic aneurysms
Christian Klausen, Nelly Auersperg BMC Physiology 2011, 11:18 (14 December 2011)
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Effect of prolonged standardized bed rest on cystatin C and other markers of cardiovascular risk
Karin Arinell, Kjeld Christensen, Stéphane Blanc, Anders Larsson, Ole Fröbert BMC Physiology 2011, 11:17 (9 December 2011)
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VEGF signaling mediates bladder neuroplasticity and inflammation in response to BCG
Marcia R Saban, Carole A Davis, Antonio Avelino, Francisco Cruz, Julie Maier, Dale E Bjorling, Thomas J Sferra, Robert E Hurst, Ricardo Saban BMC Physiology 2011, 11:16 (7 November 2011)
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Editor’s summary
Instilling Bacillus Calmette-Guerin into the mouse bladder promotes increased peripheral nerve density mimicked by vascular endothelial growth factor (VEGF) and abolished with neutralizing VEGF antibody, implicating the VEGF pathway as a key modulator of inflammation and nerve plasticity.
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Calcium sparks in the intact gerbil spiral modiolar artery
Gayathri Krishnamoorthy, Keil Regehr, Samantha Berge, Elias Q Scherer, Philine Wangemann BMC Physiology 2011, 11:15 (26 August 2011)
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Metabolomic phenotyping of a cloned pig model
Morten R Clausen, Kirstine L Christensen, Mette S Hedemann, Ying Liu, Stig Purup, Mette Schmidt, Henrik Callesen, Jan Stagsted, Hanne C Bertram BMC Physiology 2011, 11:14 (22 August 2011)
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Editor’s summary
The metabolite profile of pigs differs between cloned and normal outbred animals, however cloning does not appear to reduce variability as no significant difference in inter-individual variation is seen.
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Monitoring the wild black bear's reaction to human and environmental stressors
Timothy G Laske, David L Garshelis, Paul A Iaizzo BMC Physiology 2011, 11:13 (17 August 2011)
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Editor’s summary
Yearlong monitoring of the heart rates of wild black bears shows that during hibernation they are ready to respond to danger, and that a female bear returns to hibernation after giving birth to her cubs.
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Receptors and effects of gut hormones in three osteoblastic cell lines
Elda L Pacheco-Pantoja, Lakshminarayan R Ranganath, James A Gallagher, Peter JM Wilson, William D Fraser BMC Physiology 2011, 11:12 (29 July 2011)
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Editor’s summary
The expression of gut hormone receptors, biochemical bone markers and viability in three osteosarcoma cell lines in response to gut hormones varies depending on the stage of osteoblastic development represented by each cell line.
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Regulation of Caenorhabditis elegans vitellogenesis by DAF-2/IIS through separable transcriptional and posttranscriptional mechanisms
Ana S DePina, Wendy B Iser, Sung-Soo Park, Stuart Maudsley, Mark A Wilson, Catherine A Wolkow BMC Physiology 2011, 11:11 (12 July 2011)
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Editor’s summary
The daf-2 pathway suppresses vitellogenesis through distinct transcriptional and posttranscriptional mechanisms, revealing that the pleiotropic effects of insulin-like signaling pathway mutations can converge on a common downstream target to modulate longevity.
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The actions of exogenous leucine on mTOR signalling and amino acid transporters in human myotubes
Petra Gran, David Cameron-Smith BMC Physiology 2011, 11:10 (25 June 2011)
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Regional expression of HOXA4 along the aorta and its potential role in human abdominal aortic aneurysms
John H Lillvis, Robert Erdman, Charles M Schworer, Alicia Golden, Kimberly Derr, Zoran Gatalica, Laura A Cox, Jianbin Shen, Richard S Vander Heide, Guy M Lenk, Leigh Hlavaty, Li Li, James R Elmore, David P Franklin, John L Gray, Robert P Garvin, David J Carey, Wayne D Lancaster, Gerard Tromp, Helena Kuivaniemi BMC Physiology 2011, 11:9 (31 May 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
HOXA4 is important for maintaining spatial identity in the adult aorta and the down-regulation of HOXA4 gene expression may increase susceptibility to aortic diseases such as abdominal aortic aneurysms (AAAs).
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Non-endothelial endothelin counteracts hypoxic vasodilation in porcine large coronary arteries
Elise R Hedegaard, Edgaras Stankevicius, Ulf Simonsen, Ole Fröbert BMC Physiology 2011, 11:8 (15 May 2011)
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Nitric oxide contributes to hypoxic vasodilation in porcine coronary arteries, probably through K channel opening, which is reversed by addition of endothelin-1 enhanced by endothelin receptor antagonism, indicating that endothelin receptor activation counteracts hypoxic vasodilation.
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Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakness
Chul Kim, Sapeckshita Srivastava, Marian Rice, Tanja A Godenschwege, Brooke Bentley, Saranya Ravi, Shuang Shao, Craig T Woodard, Lawrence M Schwartz BMC Physiology 2011, 11:7 (25 April 2011)
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Editor’s summary
Ectopic expression of human amyloid precursor protein (hAPP) in fruit flies leads to age- and activity-dependent behavioral defects but does not compromise muscle development or animal longevity.
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JAK/STAT signaling and human in vitro myogenesis
Marissa K Trenerry, Paul Gatta, David Cameron-Smith BMC Physiology 2011, 11:6 (9 March 2011)
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Fatigue-inducing stimulation resolves myotonia in a drug-induced model
Erik van Lunteren, Sarah E Spiegler, Michelle Moyer BMC Physiology 2011, 11:5 (28 February 2011)
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Sodium selectivity of Reissner's membrane epithelial cells
Muneharu Yamazaki, Kyunghee X Kim, Daniel C Marcus BMC Physiology 2011, 11:4 (1 February 2011)
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Editor’s summary
The benzamil-sensitive current in epithelial cells within the Reissner’s membrane of the cochlea is highly selective for Na+ but not K+, suggesting the membrane maintains low Na+ concentration in normal endolymph but is not involved in K+ homeostasis.
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Athletic humans and horses: Comparative analysis of interleukin-6 (IL-6) and IL-6 receptor (IL-6R) expression in peripheral blood mononuclear cells in trained and untrained subjects at rest
Stefano Capomaccio, Katia Cappelli, Giacomo Spinsanti, Marzia Mencarelli, Michela Muscettola, Michela Felicetti, Andrea Supplizi, Marco Bonifazi BMC Physiology 2011, 11:3 (21 January 2011)
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Study of multiparameter respiratory pattern complexity in surgical critically ill patients during weaning trials
Vasilios E Papaioannou, Ioanna G Chouvarda, Nikos K Maglaveras, Ioannis A Pneumatikos BMC Physiology 2011, 11:2 (21 January 2011)
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Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps
Yong Qi, Kenneth A Longo, Derek J Giuliana, Samantha Gagne, Tom McDonagh, Elizabeth Govek, Anna Nolan, Chaoseng Zou, Kristen Morgan, Jeffrey Hixon, Jeffrey O Saunders, Peter S DiStefano, Brad J Geddes BMC Physiology 2011, 11:1 (6 January 2011)
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Intestinal barrier function of Atlantic salmon (Salmo salar L.) post smolts is reduced by common sea cage environments and suggested as a possible physiological welfare indicator
Henrik Sundh, Bjørn Kvamme, Frode Fridell, Rolf Olsen, Tim Ellis, Geir Taranger, Kristina Sundell BMC Physiology 2010, 10:22 (9 November 2010)
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