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Basic Pharmacology

This section considers submissions that focus on receptor pharmacology, signal transduction, pharmacokinetics and pharmacogenomics relating to all organ systems.

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1.

Research article   Open Access

Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells

Monica Pallis, Francis Burrows, Abigail Whittall, Nicholas Boddy, Claire Seedhouse, Nigel Russell BMC Pharmacology and Toxicology 2013, 14:32 (15 June 2013)

Abstract | Full text | PDF

2.

Research article   Open Access

Anvirzel™ in combination with cisplatin in breast, colon, lung, prostate, melanoma and pancreatic cancer cell lines

Panagiotis Apostolou, Maria Toloudi, Marina Chatziioannou, Eleni Ioannou, Dennis R Knocke, Joe Nester, Dimitrios Komiotis, Ioannis Papasotiriou BMC Pharmacology and Toxicology 2013, 14:18 (25 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

3.

Research article   Open Access

R- and S-Equol have equivalent cytoprotective effects in Friedreich’s Ataxia

Timothy E Richardson, James W Simpkins BMC Pharmacology and Toxicology 2012, 13:12 (22 October 2012)

Abstract | Full text | PDF | PubMed

4.

Research article   Open Access

Nitric oxide and histone deacetylases modulate cocaine-induced mu-opioid receptor levels in PC12 cells

Warren Winick-Ng, Francesco Leri, Bettina E Kalisch BMC Pharmacology and Toxicology 2012, 13:11 (18 October 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Nitric oxide and histone deacetylase activity regulate cocaine-induced Mu-opioid receptor (MOR) expression at both transcriptional and post-transcriptional levels in PC12 cells, suggesting that epigenetic mechanisms modulate cocaine's action on MOR expression in vivo.

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