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51.
145
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Long-term platinum retention after treatment with cisplatin and oxaliplatin
Elke EM Brouwers, Alwin DR Huitema, Jos H Beijnen, Jan HM Schellens BMC Clinical Pharmacology 2008, 8:7 (17 September 2008)
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Editor’s summary
Chemotherapy with platinum compounds results in retention of the metal in plasma, partly in a reactive form, but it remains unclear what long term consequences this has for the patient.
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52.
143
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A cost effectiveness analysis of the preferred antidotes for acute paracetamol poisoning patients in Sri Lanka
S M D K Ganga Senarathna, Shalini Ranganathan, Nick Buckley, Rohini Fernandopulle BMC Clinical Pharmacology 2012, 12:6 (22 February 2012)
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| PubMed | Cited on BioMed Central
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High sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection
Anders Andersen, David J Warren, Paal F Brunsvig, Steinar Aamdal, Gunnar B Kristensen, Harald Olsen BMC Clinical Pharmacology 2006, 6:2 (13 January 2006)
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Editor’s summary
A high performance liquid chromatography method which uses UV detection is capable of quantifying nM concentrations of taxanes in human plasma samples, making it suitable for the sensitive monitoring of taxane levels in people receiving low dose therapy for cancer treatment.
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Methadone vs. buprenorphine/naloxone during early opioid substitution treatment: a naturalistic comparison of cognitive performance relative to healthy controls
Pekka Rapeli, Carola Fabritius, Hannu Alho, Mikko Salaspuro, Kristian Wahlbeck, Hely Kalska BMC Clinical Pharmacology 2007, 7:5 (12 June 2007)
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Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study
Anthony Cahn, Simon Hodgson, Robert Wilson, Jonathan Robertson, Joanna Watson, Misba Beerahee, Steve C Hughes, Graeme Young, Rebecca Graves, David Hall, Sjoerd van Marle, Roberto Solari BMC Pharmacology and Toxicology 2013, 14:14 (28 February 2013)
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Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998–2005
Hitesh Patel, Derek Bell, Mariam Molokhia, Janakan Srishanmuganathan, Mitesh Patel, Josip Car, Azeem Majeed BMC Clinical Pharmacology 2007, 7:9 (25 September 2007)
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Pharmacokinetics of recombinant human growth hormone administered by cool.click™ 2, a new needle-free device, compared with subcutaneous administration using a conventional syringe and needle
Chris Brearley, Anthony Priestley, James Leighton-Scott, Michel Christen BMC Clinical Pharmacology 2007, 7:10 (8 October 2007)
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Risk of upper gastrointestinal bleeding and perforation associated
with low-dose aspirin as plain and enteric-coated formulations
Francisco J de Abajo, Luis A García Rodríguez BMC Clinical Pharmacology 2001, 1:1-1 (13 February 2001)
Abstract | Full text | PDF
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Editor’s summary
Low-dose aspirin doubles the risk of upper GI bleeding or perforation, and enteric coating makes no difference, according to a population-based case-control study.
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59.
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Comparative in vitro study of the antimicrobial activities of different commercial antibiotic products for intravenous administration
Edelberto Silva, Jorge A Díaz, María J Arias, Angela P Hernández, Andrés de la Torre BMC Clinical Pharmacology 2010, 10:3 (29 January 2010)
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Perceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria
Kazeem A Oshikoya, Jacob O Awobusuyi BMC Clinical Pharmacology 2009, 9:14 (11 August 2009)
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| PubMed | Cited on BioMed Central
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Editor’s summary
Knowledge of adverse drug reactions and the Yellow Card reporting scheme is inadequate among doctors at a teaching hospital in Lagos, Nigeria, and education and training were recognised as the best ways of improving reporting.
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61.
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The Clinical Pharmacology of Intranasal l-Methamphetamine
John E Mendelson, Dana McGlothlin, Debra S Harris, Elyse Foster, Tom Everhart, Peyton Jacob, Reese T Jones BMC Clinical Pharmacology 2008, 8:4 (21 July 2008)
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Editor’s summary
Over-the-counter nasal sprays containing l-methamphetamine, an isomer of the highly addictive drug d-methamphetamine, do not produce major dose-dependent psychological effects, and produce only minor changes in blood pressure.
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Bioequivalence of HX575 (recombinant human epoetin alfa) and a comparator epoetin alfa after multiple intravenous administrations: an open-label randomised controlled trial
Fritz Sörgel, Ursula Thyroff-Friesinger, Andrea Vetter, Bernhard Vens-Cappell, Martina Kinzig BMC Clinical Pharmacology 2009, 9:10 (22 May 2009)
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Drug safety of rosiglitazone and pioglitazone in France: a study using the French PharmacoVigilance database
Stephanie Berthet, Pascale Olivier, Jean-Louis Montastruc, Maryse Lapeyre-Mestre BMC Clinical Pharmacology 2011, 11:5 (24 May 2011)
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Editor’s summary
Treatment with Thiazolidinediones (TZDs) is associated with an increased risk of edema and heart failure in patients with type 2 diabetes, but presents a similar risk of myocardial infarction and hepatitis as with other hypoglycemic agents.
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64.
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Gastrointestinal adverse effects of varenicline at maintenance dose: a meta-analysis
Lawrence K Leung, Francis M Patafio, Walter W Rosser BMC Clinical Pharmacology 2011, 11:15 (28 September 2011)
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| PubMed | Cited on BioMed Central
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Editor’s summary
Evidence from published randomized controlled trials indicates that the smoking cessation aid varenicline is associated with major gastrointestinal adverse effects at maintenance dose of 1 mg twice a day for longer than 6 weeks.
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Assessment of single-dose benzodiazepines on insulin secretion, insulin sensitivity and glucose effectiveness in healthy volunteers: a double-blind, placebo-controlled, randomized cross-over trial [ISRCTN08745124]
Hugues Chevassus, Isabelle Mourand, Nathalie Molinier, Bruno Lacarelle, Jean-Frédéric Brun, Pierre Petit BMC Clinical Pharmacology 2004, 4:3 (4 March 2004)
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Allosteric transition: a comparison of two models
Niels Bindslev BMC Pharmacology and Toxicology 2013, 14:4 (8 January 2013)
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Pharmacokinetic comparability of Prolastin®-C to Prolastin® in alpha1-antitrypsin deficiency: a randomized study
James M Stocks, Mark L Brantly, Laurene Wang-Smith, Michael A Campos, Kenneth R Chapman, Friedrich Kueppers, Robert A Sandhaus, Charlie Strange, Gerard Turino BMC Clinical Pharmacology 2010, 10:13 (30 September 2010)
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Cognitive functioning in opioid-dependent patients treated with buprenorphine, methadone, and other psychoactive medications: stability and correlates
Pekka Rapeli, Carola Fabritius, Hely Kalska, Hannu Alho BMC Clinical Pharmacology 2011, 11:13 (21 August 2011)
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| PubMed | Cited on BioMed Central
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The future of pharmaceutical care in France: a survey of final-year pharmacy students' opinions
Clémence Perraudin, Françoise Brion, Olivier Bourdon, Nathalie Pelletier-Fleury BMC Clinical Pharmacology 2011, 11:6 (25 May 2011)
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Editor’s summary
Despite the potential barriers, final-year pharmacy students in France are keen to develop their professional skills beyond the traditional role of dispensing and to develop new practices that are more focused on the patient.
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An international survey of patients with thalassemia major and their views about sustaining life-long desferrioxamine use
Alexandra Ward, J Jaime Caro, Traci Green, Krista Huybrechts, Alejandro Arana, Suzanne Wait, Androulla Eleftheriou BMC Clinical Pharmacology 2002, 2:3 (23 April 2002)
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Errors and omissions in hospital prescriptions: a survey of prescription writing in a hospital
Laura Calligaris, Angela Panzera, Luca Arnoldo, Carla Londero, Rosanna Quattrin, Maria G Troncon, Silvio Brusaferro BMC Clinical Pharmacology 2009, 9:9 (13 May 2009)
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Editor’s summary
Illegible or incomplete prescriptions for antibiotics are common in hospitals particularly in the medical and surgical sections, suggesting urgent action to increase awareness among medical staff of potential consequent medication errors is needed.
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72.
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An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration
Almath M Spooner, Catherine Deegan, Deirdre M D'Arcy, Caitriona M Gowing, Maria B Donnelly, Owen I Corrigan BMC Clinical Pharmacology 2011, 11:11 (4 August 2011)
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Immunogenicity of panitumumab in combination chemotherapy clinical trials
Dohan Weeraratne, Alin Chen, Jason J Pennucci, Chi-Yuan Wu, Kathy Zhang, Jacqueline Wright, Juan Pérez-Ruixo, Bing-Bing Yang, Arunan Kaliyaperumal, Shalini Gupta, Steven J Swanson, Narendra Chirmule, Marta Starcevic BMC Clinical Pharmacology 2011, 11:17 (9 November 2011)
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Mechanisms for an effect of acetylcysteine on renal function after exposure to radio-graphic contrast material: study protocol
Euan A Sandilands, Sharon Cameron, Frances Paterson, Sam Donaldson, Lesley Briody, Jane Crowe, Julie Donnelly, Adrian Thompson, Neil R Johnston, Ivor Mackenzie, Neal Uren, Jane Goddard, David J Webb, Ian L Megson, Nicholas Bateman, Michael Eddleston BMC Clinical Pharmacology 2012, 12:3 (3 February 2012)
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Pharmacokinetics of isoflavones, daidzein and genistein, after ingestion of soy beverage compared with soy extract capsules in postmenopausal Thai women
Ekasin Anupongsanugool, Supanimit Teekachunhatean, Noppamas Rojanasthien, Saipin Pongsatha, Chaichan Sangdee BMC Clinical Pharmacology 2005, 5:2 (3 March 2005)
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