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	1. 745 Accesses	Review A review of the differences and similarities between generic drugs and their originator counterparts, including economic benefits associated with usage of generic medicines, using Ireland as a case study Suzanne Dunne, Bill Shannon, Colum Dunne, Walter Cullen BMC Pharmacology and Toxicology 2013, 14:1 (5 January 2013) Abstract \| Full text \| PDF \| PubMed
	2. 714 Accesses	Research article Clinical outcomes and kinetics of propanil following acute self-poisoning: a prospective case series Darren M Roberts, Renate Heilmair, Nick A Buckley, Andrew H Dawson, Mohamed Fahim, Michael Eddleston, Peter Eyer BMC Clinical Pharmacology 2009, 9:3 (16 February 2009) Abstract \| Full text \| PDF \| PubMed
	3. 695 Accesses	Research article Quantitative relationship between the octanol/water partition coefficient and the diffusion limitation of the exchange between adipose and blood David G Levitt BMC Clinical Pharmacology 2010, 10:1 (7 January 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The limited diffusion of highly fat soluble persistent organic chemicals between adipose tissue and blood can be explained because as the blood/water partition coefficient increases the adipose perfusion rate decreases.
	4. 578 Accesses	Case report Intrathecal baclofen withdrawal syndrome- a life-threatening complication of baclofen pump: A case report Imran Mohammed, Asif Hussain BMC Clinical Pharmacology 2004, 4:6 (9 August 2004) Abstract \| Full text \| PDF \| PubMed
	5. 522 Accesses	Research article Active post-marketing surveillance of the intralesional administration of human recombinant epidermal growth factor in diabetic foot ulcers Isis B Yera-Alos, Liuba Alonso-Carbonell, Carmen M Valenzuela-Silva, Angela D Tuero-Iglesias, Martha Moreira-Martínez, Ivonne Marrero-Rodríguez, Ernesto López-Mola, Pedro A López-Saura BMC Pharmacology and Toxicology 2013, 14:44 (3 September 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	6. 520 Accesses	Editorial An interview with David H Farb, Section Editor for Basic Pharmacology David H Farb BMC Pharmacology and Toxicology 2013, 14:42 (30 August 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Section Editor David Farb provides his insights on recent developments in the field of pharmacology and discusses his future aspirations for BMC Pharmacology and Toxicology.
	7. 520 Accesses	Research article Finasteride induced depression: a prospective study Babak Rahimi-Ardabili, Ramin Pourandarjani, Peiman Habibollahi, Amir Mualeki BMC Clinical Pharmacology 2006, 6:7 (7 October 2006) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	8. 482 Accesses	Research article Effects of simvastatin 40 mg daily on muscle and liver adverse effects in a 5-year randomized placebo-controlled trial in 20,536 high-risk people MRC/BHF Heart Protection Study Collaborative Group BMC Clinical Pharmacology 2009, 9:6 (31 March 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Simvastatin treatment for patients at high risk of cardiovascular events or with diabetes results in only a minor increase in the risk of myopathy and hepatobiliary diseases over 5 years of use.
	9. 472 Accesses	Research article Assessing the translatability of In vivo cardiotoxicity mechanisms to In vitro models using causal reasoning Ahmed E Enayetallah, Dinesh Puppala, Daniel Ziemek, James E Fischer, Sheila Kantesaria, Mathew T Pletcher BMC Pharmacology and Toxicology 2013, 14:46 (6 September 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	10. 435 Accesses	Research article Application of microbiological assay to determine pharmaceutical equivalence of generic intravenous antibiotics Andres F Zuluaga, Maria Agudelo, Carlos A Rodriguez, Omar Vesga BMC Clinical Pharmacology 2009, 9:1 (16 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Pharmaceutical equivalence of generic intravenous antibiotics can be assessed prior to their clinical use by providing information about potency and efficacy using a new microbiological assay with reference bacteria
	11. 434 Accesses	Debate Promiscuous drugs compared to selective drugs (promiscuity can be a virtue) Simon K Mencher, Long G Wang BMC Clinical Pharmacology 2005, 5:3 (26 April 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Truly selective drugs may be less desirable than more 'promiscuous' drugs which correct the imbalance of several molecules involved in a disease process; this viewpoint has implications for current research trends focused on drug selectivity.
	12. 414 Accesses	Case report Rifampicin-warfarin interaction leading to macroscopic hematuria: a case report and review of the literature Maria AP Martins, Adriano MM Reis, Mariana F Sales, Vandack Nobre, Daniel D Ribeiro, Manoel OC Rocha, Antônio LP Ribeiro BMC Pharmacology and Toxicology 2013, 14:27 (4 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	13. 421 Accesses	Research article Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects Howard A Smithline, Michael Donnino, David J Greenblatt BMC Clinical Pharmacology 2012, 12:4 (4 February 2012) Abstract \| Full text \| PDF \| PubMed
	14. 412 Accesses	Research article Perceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria Kazeem A Oshikoya, Jacob O Awobusuyi BMC Clinical Pharmacology 2009, 9:14 (11 August 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Knowledge of adverse drug reactions and the Yellow Card reporting scheme is inadequate among doctors at a teaching hospital in Lagos, Nigeria, and education and training were recognised as the best ways of improving reporting.
	15. 409 Accesses	Research article Bioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers Peter M Dewland, Sandie Reader, Phillip Berry BMC Clinical Pharmacology 2009, 9:19 (4 December 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The time to maximum blood concentration of ibuprofen is cut from 90 minutes to just 35 minutes if ibuprofen sodium dihydrate is taken rather than the standard formulation, but adding poloxamer makes no significant difference to bioavailability.
	16. 397 Accesses	Case report Tissue concentration of paraquat on day 32 after intoxication and failed bridge to transplantation by extracorporeal membrane oxygenation therapy Anna Bertram, Sascha Sebastian Haenel, Johannes Hadem, Marius M Hoeper, Jens Gottlieb, Gregor Warnecke, Stanislav Kaschinski, Carsten Hafer, W Nikolaus Kühn-Velten, Detlef Günther, Jan T Kielstein BMC Pharmacology and Toxicology 2013, 14:45 (6 September 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	17. 358 Accesses	Research article Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part A - Medical results James B Adams, Matthew Baral, Elizabeth Geis, Jessica Mitchell, Julie Ingram, Andrea Hensley, Irene Zappia, Sanford Newmark, Eva Gehn, Robert A Rubin, Ken Mitchell, Jeff Bradstreet, Jane El-Dahr BMC Clinical Pharmacology 2009, 9:16 (23 October 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	18. 351 Accesses	Research article Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats Nagesh Gowda, Anilkumar Dandu, Jaideep Singh, Sanghamitra Biswas, Vijaya Raghav, Mudigere N Lakshmi, Pavagada C Shilpa, Venkategowda Sunil, Ashokkumar Reddy, Manojkumar Sadasivuni, Kumaraswamy Aparna, Mahesh Verma, Yoganand Moolemath, Mammen O Anup, Marikunte V Venkataranganna, Baggavalli P Somesh, Madanahalli R Jagannath BMC Pharmacology and Toxicology 2013, 14:28 (21 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Rats treated with CNX-011-67 demonstrate improved glucose mediated insulin secretion and insulin gene transcription, enhanced glucose oxidation in the form of increased islet ATP content and overall improvement in beta cell health.
	19. 343 Accesses	Research article Polycomblike protein PHF1b: a transcriptional sensor for GABA receptor activity Shamol Saha, Yinghui Hu, Stella C Martin, Sabita Bandyopadhyay, Shelley J Russek, David H Farb BMC Pharmacology and Toxicology 2013, 14:37 (23 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Polycomblike protein PHF1b stimulates GABRB1 promoter activity in primary cultured neurons and chronic GABA exposure regulates PHF1 binding to endogenous Gabrb1 indicating its role as a molecular transducer of GABA-mediated neurotransmission.
	20. 316 Accesses	Research article Tocopheryl acetate 20% spray for elimination of head louse infestation: a randomised controlled trial comparing with 1% permethrin creme rinse Ian F Burgess, Nazma A Burgess, Elizabeth R Brunton BMC Pharmacology and Toxicology 2013, 14:43 (3 September 2013) Abstract \| Full text \| PDF \| PubMed
	21. 310 Accesses	Research article Adherence to medication for the treatment of psychosis: rates and risk factors in an Ethiopian population Menna Alene, Michael D Wiese, Mulugeta T Angamo, Beata V Bajorek, Elias A Yesuf, Nasir Wabe BMC Clinical Pharmacology 2012, 12:10 (18 June 2012) Abstract \| Full text \| PDF \| PubMed
	22. 307 Accesses	Research article The pharmacokinetic profile of a novel fixed-dose combination tablet of ibuprofen and paracetamol Trevor Tanner, Sue Aspley, Andrew Munn, Tracy Thomas BMC Clinical Pharmacology 2010, 10:10 (5 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Paracetemol is absorbed significantly faster when taken in a combination dose with ibuprofen compared to when taken in isolation, with greater blood plasma concentrations of both being reached earlier, offering potentially enhanced pain relief.
	23. 292 Accesses	Research article Coumestrol from the national cancer Institute’s natural product library is a novel inhibitor of protein kinase CK2 Shu Liu, David Hsieh, Yi-Lin Yang, Zhidong Xu, Csaba Peto, David M Jablons, Liang You BMC Pharmacology and Toxicology 2013, 14:36 (11 July 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed \| Editor’s summary Cell-free, in vitro and molecular docking studies indicate that the phytoestrogen coumestrol is a novel ATP competitive and cell permeable Casein kinase 2 (CK2) inhibitor with a submicromolar IC₅₀.
	24. 288 Accesses	Review Role of astrocytes in manganese mediated neurotoxicity Marta Sidoryk-Wegrzynowicz, Michael Aschner BMC Pharmacology and Toxicology 2013, 14:23 (18 April 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	25. 288 Accesses	Technical advance Validation of an LC-MS/MS method to determine five immunosuppressants with deuterated internal standards including MPA Armin Buchwald, Karl Winkler, Thomas Epting BMC Clinical Pharmacology 2012, 12:2 (11 January 2012) Abstract \| Full text \| PDF \| PubMed