Most Recent Articles: BMC Pharmacology and Toxicologyhttps://bmcpharmacoltoxicol.biomedcentral.comMost Recent Articles: BMC Pharmacology and ToxicologyImmuno-oncological effects of standard anticancer agents and commonly used concomitant drugs: an in vitro assessmenthttps://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-024-00746-6It has become evident in the field of oncology that the outcome of medical treatment is influenced by the combined effect exerted on both cancer- and immune cells. Therefore, we evaluated potential immunologic...ResearchTue, 05 Mar 2024 00:00:00 GMThttps://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-024-00746-6Tove Selvin, Malin Berglund, Lena Lenhammar, Magnus Lindskog, Malin Jarvius, Rolf Larsson, Peter Nygren, Mårten Fryknäs and Claes R Andersson2024-03-05T00:00:00ZRisk of CKD among patients with DM taking diuretics or SGLT2i: a retrospective cohort study in Taiwanhttps://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-024-00745-7This study aimed to evaluate the long-term risk of CKD and renal function declines using a combination of diuretics and SGLT2i.ResearchTue, 05 Mar 2024 00:00:00 GMThttps://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-024-00745-7Han-Jie Lin, Pin-Yang Shih, Stella Chin-Shaw Tsai, Wu-Lung Chuang, Tsai-Ling Hsieh, Heng-Jun Lin, Teng-Shun Yu, Fuu-Jen Tsai, Chiu-Ying Chen and Kuang-Hsi Chang2024-03-05T00:00:00ZPharmacokinetics and bioequivalence evaluation of two oral formulations of cotrimoxazole tablets in healthy Chinese volunteers under fasting conditionshttps://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-024-00743-9This bioequivalence study was conducted to evaluate two oral formulations of cotrimoxazole tablets in healthy Chinese subjects. All 26 subjects recruited to this study were randomly and evenly classified into ...ResearchTue, 27 Feb 2024 00:00:00 GMThttps://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-024-00743-9Xu Zuo, Xin Zhao, Jinjin Shi and Tiandong Zhang2024-02-27T00:00:00ZIron overload induced submandibular glands toxicity in gamma irradiated rats with possible mitigation by hesperidin and rutinhttps://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-024-00744-8Radiation triggers salivary gland damage and excess iron accumulates in tissues induces cell injury. Flavonoids are found in some fruits and are utilized as potent antioxidants and radioprotective agents. This...ResearchTue, 27 Feb 2024 00:00:00 GMThttps://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-024-00744-8Salwa Farid Ahmed, Eman M. F. El-Maghraby, Maha M. Rashad and Dina W. Bashir2024-02-27T00:00:00ZPreparation and evaluation of transdermal permeation of Huperzine A ethosomes gel in vitrohttps://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-024-00742-wThis study aimed to design and evaluate the transdermal permeation of Huperzine A ethosomes gel in vitro. Huperzine A ethosomes were prepared using the injection method, and their physical and chemical propert...ResearchMon, 26 Feb 2024 00:00:00 GMThttps://bmcpharmacoltoxicol.biomedcentral.com/articles/10.1186/s40360-024-00742-wJiyu Wu, Renai Xu, Xiaowei Xu, Shiyuan Ye and Aifang Huang2024-02-26T00:00:00Z