BMC Pharmacology and Toxicology

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		Research article Use of and attitudes towards the prescribing guidelines booklet in primary health care doctors Magnus AB Axelsson, Malin Spetz, Anders Mellén, Susanna M Wallerstedt BMC Clinical Pharmacology 2008, 8:8 (22 September 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Long-term platinum retention after treatment with cisplatin and oxaliplatin Elke EM Brouwers, Alwin DR Huitema, Jos H Beijnen, Jan HM Schellens BMC Clinical Pharmacology 2008, 8:7 (17 September 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Chemotherapy with platinum compounds results in retention of the metal in plasma, partly in a reactive form, but it remains unclear what long term consequences this has for the patient.
		Research article Antihypertensive drug class and impaired fasting glucose: a risk association study among Chinese patients with uncomplicated hypertension Martin CS Wong, Johnny Y Jiang, H Fung, Sian Griffiths, Stewart Mercer BMC Clinical Pharmacology 2008, 8:6 (10 September 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Optimizing bioavailability of oral administration of small peptides through pharmacokinetic and pharmacodynamic parameters: The effect of water and timing of meal intake on oral delivery of Salmon Calcitonin Morten A Karsdal, Inger Byrjalsen, Bente J Riis, Claus Christiansen BMC Clinical Pharmacology 2008, 8:5 (9 September 2008) Abstract \| Full text \| PDF \| PubMed
		Research article The Clinical Pharmacology of Intranasal l-Methamphetamine John E Mendelson, Dana McGlothlin, Debra S Harris, Elyse Foster, Tom Everhart, Peyton Jacob, Reese T Jones BMC Clinical Pharmacology 2008, 8:4 (21 July 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Over-the-counter nasal sprays containing l-methamphetamine, an isomer of the highly addictive drug d-methamphetamine, do not produce major dose-dependent psychological effects, and produce only minor changes in blood pressure.
		Research article Evaluation of safe and effective administration of nitrous oxide after a postgraduate training course Valérie Collado, Emmanuel Nicolas, Denise Faulks, Corinne Tardieu, Marie-Cécile Manière, Dominique Droz, Peter Onody, Martine Hennequin BMC Clinical Pharmacology 2008, 8:3 (11 June 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Training dentists in conscious sedation enables safe and effective administration of a 50% nitrous oxide in oxygen premix, but additional training in behavior management is needed to sedate patients with intellectual disability.
		Research article Renal safety of zoledronic acid with thalidomide in patients with myeloma: a pharmacokinetic and safety sub-study Andrew Spencer, Andrew Roberts, Nola Kennedy, Christina Ravera, Serge Cremers, Sanela Bilic, Terry Neeman, Michael Copeman, Horst Schran, Kevin Lynch BMC Clinical Pharmacology 2008, 8:2 (31 March 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Individual case safety reports in children in commonly used drug groups – signal detection Gertrud Brunlöf, Carina Tukukino, Susanna M Wallerstedt BMC Clinical Pharmacology 2008, 8:1 (17 March 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Aspects of statin prescribing in Norwegian counties with high, average and low statin consumption – an individual-level prescription database study Ingeborg Hartz, Solveig Sakshaug, Kari Furu, Anders Engeland, Anne Eggen, Inger Njølstad, Svetlana Skurtveit BMC Clinical Pharmacology 2007, 7:14 (5 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Antimalarial activity of the anticancer and proteasome inhibitor bortezomib and its analog ZL₃B Jennifer M Reynolds, Kamal El Bissati, Jens Brandenburg, Arthur Günzl, Choukri Mamoun BMC Clinical Pharmacology 2007, 7:13 (23 October 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Influence of an e-mail with a drug information attachment on sales of prescribed drugs: a randomized controlled study Christina Edward, Anders Himmelmann, Susanna M Wallerstedt BMC Clinical Pharmacology 2007, 7:12 (18 October 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Pharmacokinetics, safety and efficacy from randomized controlled trials of 1 and 2 mg nicotine bitartrate lozenges (Nicotinell^®) Bertrand Dautzenberg, Mitchell Nides, Jean-Luc Kienzler, Anne Callens BMC Clinical Pharmacology 2007, 7:11 (8 October 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Pharmacokinetics of recombinant human growth hormone administered by cool.click™ 2, a new needle-free device, compared with subcutaneous administration using a conventional syringe and needle Chris Brearley, Anthony Priestley, James Leighton-Scott, Michel Christen BMC Clinical Pharmacology 2007, 7:10 (8 October 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998–2005 Hitesh Patel, Derek Bell, Mariam Molokhia, Janakan Srishanmuganathan, Mitesh Patel, Josip Car, Azeem Majeed BMC Clinical Pharmacology 2007, 7:9 (25 September 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Evaluation of the prevalence and economic burden of adverse drug reactions presenting to the medical emergency department of a tertiary referral centre: a prospective study KJ Patel, MS Kedia, D Bajpai, SS Mehta, NA Kshirsagar, NJ Gogtay BMC Clinical Pharmacology 2007, 7:8 (28 July 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Expression of thymidine phosphorylase in peripheral blood cells of breast cancer patients is not increased by paclitaxel Rupert Bartsch, Guenther G Steger, Birgit Forstner, Catharina Wenzel, Ursula Pluschnig, Blanka Rizovski, Gabriela Altorjai, Christoph C Zielinski, Robert M Mader BMC Clinical Pharmacology 2007, 7:7 (18 July 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Phenotype-genotype analysis of CYP2C19 in Colombian mestizo individuals Carlos Isaza, Julieta Henao, José Martínez, Juan Arias, Leonardo Beltrán BMC Clinical Pharmacology 2007, 7:6 (11 July 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Methadone vs. buprenorphine/naloxone during early opioid substitution treatment: a naturalistic comparison of cognitive performance relative to healthy controls Pekka Rapeli, Carola Fabritius, Hannu Alho, Mikko Salaspuro, Kristian Wahlbeck, Hely Kalska BMC Clinical Pharmacology 2007, 7:5 (12 June 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Correspondence Does atenolol differ from other β-adrenergic blockers? Ivar Aursnes, Jan-Bjørn Osnes, Ingunn Tvete, Jørund Gåsemyr, Bent Natvig BMC Clinical Pharmacology 2007, 7:4 (8 May 2007) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Hypertensive people taking non-atenolol beta blockers have a significantly lower risk of myocardial infarction than those taking atenolol, suggesting that atenolol is not a typical member of the beta blocker class of drugs.
		Research article Pharmacokinetic investigation of dose proportionality with a 24-hour controlled-release formulation of hydromorphone Gayatri Sathyan, Emily Xu, John Thipphawong, Suneel K Gupta BMC Clinical Pharmacology 2007, 7:3 (2 February 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Pharmacokinetic profile of a 24-hour controlled-release OROS^®formulation of hydromorphone in the presence and absence of food Gayatri Sathyan, Emily Xu, John Thipphawong, Suneel K Gupta BMC Clinical Pharmacology 2007, 7:2 (2 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Heterogeneity of human adipose blood flow David G Levitt BMC Clinical Pharmacology 2007, 7:1 (20 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Evaluation of the activity of CYP2C19 in Gujrati and Marwadi subjects living in Mumbai (Bombay) Tanmay S Panchabhai, Shaun F Noronha, Sanish Davis, Vishal M Shinde, Nilima A Kshirsagar, Nithya J Gogtay BMC Clinical Pharmacology 2006, 6:8 (24 October 2006) Abstract \| Full text \| PDF \| PubMed
		Research article Finasteride induced depression: a prospective study Babak Rahimi-Ardabili, Ramin Pourandarjani, Peiman Habibollahi, Amir Mualeki BMC Clinical Pharmacology 2006, 6:7 (7 October 2006) Abstract \| Full text \| PDF \| PubMed \| 1 comment
		Research article Accumulation of the solvent vehicle sulphobutylether beta cyclodextrin sodium in critically ill patients treated with intravenous voriconazole under renal replacement therapy Marc A von Mach, Jürgen Burhenne, Ludwig S Weilemann BMC Clinical Pharmacology 2006, 6:6 (18 September 2006) Abstract \| Full text \| PDF \| PubMed \| 1 comment

	All
		Research article Use of and attitudes towards the prescribing guidelines booklet in primary health care doctors Magnus AB Axelsson, Malin Spetz, Anders Mellén, Susanna M Wallerstedt BMC Clinical Pharmacology 2008, 8:8 (22 September 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Long-term platinum retention after treatment with cisplatin and oxaliplatin Elke EM Brouwers, Alwin DR Huitema, Jos H Beijnen, Jan HM Schellens BMC Clinical Pharmacology 2008, 8:7 (17 September 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Chemotherapy with platinum compounds results in retention of the metal in plasma, partly in a reactive form, but it remains unclear what long term consequences this has for the patient.
		Research article Antihypertensive drug class and impaired fasting glucose: a risk association study among Chinese patients with uncomplicated hypertension Martin CS Wong, Johnny Y Jiang, H Fung, Sian Griffiths, Stewart Mercer BMC Clinical Pharmacology 2008, 8:6 (10 September 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Optimizing bioavailability of oral administration of small peptides through pharmacokinetic and pharmacodynamic parameters: The effect of water and timing of meal intake on oral delivery of Salmon Calcitonin Morten A Karsdal, Inger Byrjalsen, Bente J Riis, Claus Christiansen BMC Clinical Pharmacology 2008, 8:5 (9 September 2008) Abstract \| Full text \| PDF \| PubMed
		Research article The Clinical Pharmacology of Intranasal l-Methamphetamine John E Mendelson, Dana McGlothlin, Debra S Harris, Elyse Foster, Tom Everhart, Peyton Jacob, Reese T Jones BMC Clinical Pharmacology 2008, 8:4 (21 July 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Over-the-counter nasal sprays containing l-methamphetamine, an isomer of the highly addictive drug d-methamphetamine, do not produce major dose-dependent psychological effects, and produce only minor changes in blood pressure.
		Research article Evaluation of safe and effective administration of nitrous oxide after a postgraduate training course Valérie Collado, Emmanuel Nicolas, Denise Faulks, Corinne Tardieu, Marie-Cécile Manière, Dominique Droz, Peter Onody, Martine Hennequin BMC Clinical Pharmacology 2008, 8:3 (11 June 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Training dentists in conscious sedation enables safe and effective administration of a 50% nitrous oxide in oxygen premix, but additional training in behavior management is needed to sedate patients with intellectual disability.
		Research article Renal safety of zoledronic acid with thalidomide in patients with myeloma: a pharmacokinetic and safety sub-study Andrew Spencer, Andrew Roberts, Nola Kennedy, Christina Ravera, Serge Cremers, Sanela Bilic, Terry Neeman, Michael Copeman, Horst Schran, Kevin Lynch BMC Clinical Pharmacology 2008, 8:2 (31 March 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Individual case safety reports in children in commonly used drug groups – signal detection Gertrud Brunlöf, Carina Tukukino, Susanna M Wallerstedt BMC Clinical Pharmacology 2008, 8:1 (17 March 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Aspects of statin prescribing in Norwegian counties with high, average and low statin consumption – an individual-level prescription database study Ingeborg Hartz, Solveig Sakshaug, Kari Furu, Anders Engeland, Anne Eggen, Inger Njølstad, Svetlana Skurtveit BMC Clinical Pharmacology 2007, 7:14 (5 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Antimalarial activity of the anticancer and proteasome inhibitor bortezomib and its analog ZL₃B Jennifer M Reynolds, Kamal El Bissati, Jens Brandenburg, Arthur Günzl, Choukri Mamoun BMC Clinical Pharmacology 2007, 7:13 (23 October 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Influence of an e-mail with a drug information attachment on sales of prescribed drugs: a randomized controlled study Christina Edward, Anders Himmelmann, Susanna M Wallerstedt BMC Clinical Pharmacology 2007, 7:12 (18 October 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Pharmacokinetics, safety and efficacy from randomized controlled trials of 1 and 2 mg nicotine bitartrate lozenges (Nicotinell^®) Bertrand Dautzenberg, Mitchell Nides, Jean-Luc Kienzler, Anne Callens BMC Clinical Pharmacology 2007, 7:11 (8 October 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Pharmacokinetics of recombinant human growth hormone administered by cool.click™ 2, a new needle-free device, compared with subcutaneous administration using a conventional syringe and needle Chris Brearley, Anthony Priestley, James Leighton-Scott, Michel Christen BMC Clinical Pharmacology 2007, 7:10 (8 October 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Trends in hospital admissions for adverse drug reactions in England: analysis of national hospital episode statistics 1998–2005 Hitesh Patel, Derek Bell, Mariam Molokhia, Janakan Srishanmuganathan, Mitesh Patel, Josip Car, Azeem Majeed BMC Clinical Pharmacology 2007, 7:9 (25 September 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Evaluation of the prevalence and economic burden of adverse drug reactions presenting to the medical emergency department of a tertiary referral centre: a prospective study KJ Patel, MS Kedia, D Bajpai, SS Mehta, NA Kshirsagar, NJ Gogtay BMC Clinical Pharmacology 2007, 7:8 (28 July 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Expression of thymidine phosphorylase in peripheral blood cells of breast cancer patients is not increased by paclitaxel Rupert Bartsch, Guenther G Steger, Birgit Forstner, Catharina Wenzel, Ursula Pluschnig, Blanka Rizovski, Gabriela Altorjai, Christoph C Zielinski, Robert M Mader BMC Clinical Pharmacology 2007, 7:7 (18 July 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Phenotype-genotype analysis of CYP2C19 in Colombian mestizo individuals Carlos Isaza, Julieta Henao, José Martínez, Juan Arias, Leonardo Beltrán BMC Clinical Pharmacology 2007, 7:6 (11 July 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Methadone vs. buprenorphine/naloxone during early opioid substitution treatment: a naturalistic comparison of cognitive performance relative to healthy controls Pekka Rapeli, Carola Fabritius, Hannu Alho, Mikko Salaspuro, Kristian Wahlbeck, Hely Kalska BMC Clinical Pharmacology 2007, 7:5 (12 June 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Correspondence Does atenolol differ from other β-adrenergic blockers? Ivar Aursnes, Jan-Bjørn Osnes, Ingunn Tvete, Jørund Gåsemyr, Bent Natvig BMC Clinical Pharmacology 2007, 7:4 (8 May 2007) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Hypertensive people taking non-atenolol beta blockers have a significantly lower risk of myocardial infarction than those taking atenolol, suggesting that atenolol is not a typical member of the beta blocker class of drugs.
		Research article Pharmacokinetic investigation of dose proportionality with a 24-hour controlled-release formulation of hydromorphone Gayatri Sathyan, Emily Xu, John Thipphawong, Suneel K Gupta BMC Clinical Pharmacology 2007, 7:3 (2 February 2007) Abstract \| Full text \| PDF \| PubMed
		Research article Pharmacokinetic profile of a 24-hour controlled-release OROS^®formulation of hydromorphone in the presence and absence of food Gayatri Sathyan, Emily Xu, John Thipphawong, Suneel K Gupta BMC Clinical Pharmacology 2007, 7:2 (2 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Heterogeneity of human adipose blood flow David G Levitt BMC Clinical Pharmacology 2007, 7:1 (20 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Evaluation of the activity of CYP2C19 in Gujrati and Marwadi subjects living in Mumbai (Bombay) Tanmay S Panchabhai, Shaun F Noronha, Sanish Davis, Vishal M Shinde, Nilima A Kshirsagar, Nithya J Gogtay BMC Clinical Pharmacology 2006, 6:8 (24 October 2006) Abstract \| Full text \| PDF \| PubMed
		Research article Finasteride induced depression: a prospective study Babak Rahimi-Ardabili, Ramin Pourandarjani, Peiman Habibollahi, Amir Mualeki BMC Clinical Pharmacology 2006, 6:7 (7 October 2006) Abstract \| Full text \| PDF \| PubMed \| 1 comment
		Research article Accumulation of the solvent vehicle sulphobutylether beta cyclodextrin sodium in critically ill patients treated with intravenous voriconazole under renal replacement therapy Marc A von Mach, Jürgen Burhenne, Ludwig S Weilemann BMC Clinical Pharmacology 2006, 6:6 (18 September 2006) Abstract \| Full text \| PDF \| PubMed \| 1 comment