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Volume 9 (2009) - January 2009

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Research article   Open Access

A glycosylated recombinant human granulocyte colony stimulating factor produced in a novel protein production system (AVI-014) in healthy subjects: a first-in human, single dose, controlled study

Roslyn Varki, Ed Pequignot, Mark C Leavitt, Andres Ferber, Walter K Kraft BMC Clinical Pharmacology 2009, 9:2 (28 January 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A new, egg white-derived, recombinant glycosylated colony stimulating factor is equally safe and has similar pharmacokinetic and pharmacological properties to the first commercially available colony stimulating factor when tested on healthy individuals.

Research article   Open Access Highly Accessed

Application of microbiological assay to determine pharmaceutical equivalence of generic intravenous antibiotics

Andres F Zuluaga, Maria Agudelo, Carlos A Rodriguez, Omar Vesga BMC Clinical Pharmacology 2009, 9:1 (16 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Pharmaceutical equivalence of generic intravenous antibiotics can be assessed prior to their clinical use by providing information about potency and efficacy using a new microbiological assay with reference bacteria