BMC Pharmacology | Vol 11 | 2011

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Volume 11 (2011) - September 2011

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Protection of protease-activated receptor 2 mediated vasodilatation against angiotensin II-induced vascular dysfunction in mice

Elizabeth Chia, Satomi Kagota, Enoka P Wijekoon, John J McGuire BMC Pharmacology 2011, 11:10 (28 September 2011)

Abstract | Full text | PDF | PubMed | Editor’s summary

Vasodilatation mediated by protease-activated receptor 2 (PAR2) is retained in a mouse model of Angiotensin-II induced hypertension and mesenteric arterial vascular dysfunction, through a mechanism dependent on the calcium-activated potassium channel SK3.1.