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Volume 11 (2011) - April 2011

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Research article   Open Access Highly Accessed

Altered 5-HT2C receptor agonist-induced responses and 5-HT2C receptor RNA editing in the amygdala of serotonin transporter knockout mice

Pablo R Moya, Meredith A Fox, Catherine L Jensen, Justin L Laporte, Helen T French, Jens R Wendland, Dennis L Murphy BMC Pharmacology 2011, 11:3 (7 April 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Knock-out mice for the serotonin transporter (SERT) are impaired in the anxiogenic response induced by serotonin receptor agonists and display an increased editing of the serotonin 5-HT2C receptor RNA compared to wild-type.