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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Danielle Burgess PhD


Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents. BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus and Google Scholar.



BMC  Featured articles   

BMC Pharmacology 2009, 9:12
A drug delivery vehicle that uses the non-toxic heavy chain of botulinum neurotoxin-A to gain entry to neurons via endocytosis could rescue synapses poisoned by botox, once an effective antidote is found.
BMC Pharmacology 2009, 9:10
Amphiphilic psychotropic drugs stimulate cellular lipid biosynthesis and concomitantly upregulate mRNA levels of key genes in reverse cholesterol transport and lipid efflux in cultured human central nervous system and liver cells.


BMC  Latest supplements published in BMC Pharmacology


Volume 9 Suppl 2
Meeting abstracts
Graz, Austria. 19-21 November 2009

Volume 9 Suppl 1
Meeting abstracts
Regensburg, Germany. 1921 June 2009





BMC  Latest articles published in BMC Pharmacology        [more info]


Research article
An efficient drug delivery vehicle for botulism countermeasure
Peng Zhang, Radharaman Ray, Bal Ram Singh, Dan Li, Michael Adler, Prabhati Ray
BMC Pharmacology 2009, 9:12 (27October2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Evaluation of molecular descriptors for antitumor drugs with respect to noncovalent binding to DNA and antiproliferative activity
Jos Portugal
BMC Pharmacology 2009, 9:11 (16September2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells
Audun O Vik-Mo, Johan Fern, Silje Skrede, Vidar M Steen
BMC Pharmacology 2009, 9:10 (29August2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen
Rebecca A Roof, David L Roman, Samuel T Clements, Katarzyna Sobczyk-Kojiro, Levi L Blazer, Shodai Ota, Henry I Mosberg, Richard R Neubig
BMC Pharmacology 2009, 9:9 (22May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models
Nancy Lee, Chelsey L Woodrum, Alison M Nobil, Aubrey E Rauktys, Michael P Messina, Sandra L Dabora
BMC Pharmacology 2009, 9:8 (15April2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes
Rong Shi, Chuan-Chin Huang, Robert S Aronstam, Nuran Ercal, Adam Martin, Yue-Wern Huang
BMC Pharmacology 2009, 9:7 (15April2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Haloperidol changes mRNA expression of a QKI splice variant in human astrocytoma cells
Lin Jiang, Peter Saetre, Elena Jazin, Eva Lindholm Carlstrm
BMC Pharmacology 2009, 9:6 (31March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Preferential uptake of the non steroid anti-inflammatory drug diclofenac into inflamed tissues after a single oral dose in rats
A Schweitzer, N Hasler-Nguyen, J Zijlstra
BMC Pharmacology 2009, 9:5 (16March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Bioinformatic characterizations and prediction of K+ and Na+ ion channels effector toxins
Rima Soli, Belhassen Kaabi, Mourad Barhoumi, Mohamed El-Ayeb, Najet Srairi-Abid
BMC Pharmacology 2009, 9:4 (10March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
The mode of action of dimeticone 4% lotion against head lice, Pediculus capitis
Ian F Burgess
BMC Pharmacology 2009, 9:3 (20February2009)
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BMC  Latest relevant articles from other journals in BioMed Central


Case Report
Fluconazole induced toxic epidermal necrolysis: a case report
Uchenna R Ofoma, Edward K Chapnick
Cases Journal 2009, 2:9071 (20November2009)
[Abstract] [Provisional PDF]

Research article
Topical recombinant thrombin at a concentration of 1000 IU/mL reliably shortens in vivo TTH and delivers durable hemostasis in the presence of heparin anticoagulation and clopidogrel platelet inhibition in a rabbit model of vascular bleeding
Steven D Hughes, Paul D Bishop, Richard Garcia, Tracy Zhang, W. Allan Alexander
Annals of Surgical Innovation and Research 2009, 3:14 (19November2009)
[Abstract] [Provisional PDF]

Research
Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo
Vijayan Gangadharan, Nitin Agarwal, Stefan Brugger, Imgard Tegeder, Bernhard Bettler, Rohini Kuner, Martina Kurejova
Molecular Pain 2009, 5:68 (19November2009)
[Abstract] [Provisional PDF]

Case Report
Acitretin-associated erectile dysfunction: a case report
Marco Rossi, Michele Pellegrino
Cases Journal 2009, 2:210 (19November2009)
[Abstract] [Provisional PDF]

Review
Hypothesis of snake and insect venoms against Human Immunodeficiency Virus: a review
Ramachandran Meenakshisundaram, Shah Sweni, Ponniah Thirumalaikolundusubramanian
AIDS Research and Therapy 2009, 6:25 (19November2009)
[Abstract] [Provisional PDF]

Debate
Enhanced ERbeta immunoexpression and apoptosis in the germ cells of cimetidine-treated rats
Estela Sasso-Cerri
Reproductive Biology and Endocrinology 2009, 7:127 (18November2009)
[Abstract] [Provisional PDF]

Case Report
The usefulness of chelation therapy for the remission of symptoms caused by previous treatment with mercury-containing pharmaceuticals: a case report
Serafina Corsello, Alessandro Fulgenzi, Daniele Vietti, Maria Elena Ferrero
Cases Journal 2009, 2:199 (18November2009)
[Abstract] [Provisional PDF]

Research article
Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells
Hiroshi Izuta, Masamitsu Shimazawa, Kazuhiro Tsuruma, Yoko Araki, Satoshi Mishima, Hideaki Hara
BMC Complementary and Alternative Medicine 2009, 9:45 (17November2009)
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Research
CD10 expression in urothelial carcinoma of the bladder
Burak Bahadir, Kemal Behzatoglu, Sibel Bektas, Erol R Bozkurt, Sukru O Ozdamar
Diagnostic Pathology 2009, 4:38 (16November2009)
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Research
The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres
James W Crane, Gilang P Baiquni, Robert KP Sullivan, John D Lee, Pankaj Sah, Stephen M Taylor, Peter G Noakes, Trent M Woodruff
Journal of Neuroinflammation 2009, 6:34 (16November2009)
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