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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Scott Edmunds, PhD


Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents. BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.



BMC  Featured articles   

Credit: Nathan S. Ivey, Creative Commons 3.0
BMC Pharmacology 2009, 9:6
Human astrocytoma cells treated with the antipsychotic drug haloperidol show increased mRNA expression of QK1, a gene previously identified as a candidate gene for schizophrenia.
Louse untreated thoracic spiracle. Fig 3 by Burgess IF
BMC Pharmacology 2009, 9:3
Treatment with dimeticone blocks the spiracles of headlice but does not cause instant asphyxiation - instead the lice die slowly as water loss through the spiracles is impeded, causing physiological stress and occasionally osmotic rupture of the gut.


BMC  Related content published in BMC Neurology


Washington, DC, USA. 2-3 February 2009
BMC Neurology 2009, 9(Suppl 1)
[Content]



BMC  Latest articles published in BMC Pharmacology        [more info]


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A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen
Rebecca A Roof, David L Roman, Samuel T Clements, Katarzyna Sobczyk-Kojiro, Levi L Blazer, Shodai Ota, Henry I Mosberg, Richard R Neubig
BMC Pharmacology 2009, 9:9 (22May2009)
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Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models
Nancy Lee, Chelsey L Woodrum, Alison M Nobil, Aubrey E Rauktys, Michael P Messina, Sandra L Dabora
BMC Pharmacology 2009, 9:8 (15April2009)
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N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes
Rong Shi, Chuan-Chin Huang, Robert S Aronstam, Nuran Ercal, Adam Martin, Yue-Wern Huang
BMC Pharmacology 2009, 9:7 (15April2009)
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Haloperidol changes mRNA expression of a QKI splice variant in human astrocytoma cells
Lin Jiang, Peter Saetre, Elena Jazin, Eva Lindholm Carlstrm
BMC Pharmacology 2009, 9:6 (31March2009)
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Preferential uptake of the non steroid anti-inflammatory drug diclofenac into inflamed tissues after a single oral dose in rats
A Schweitzer, N Hasler-Nguyen, J Zijlstra
BMC Pharmacology 2009, 9:5 (16March2009)
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Bioinformatic characterizations and prediction of K+ and Na+ ion channels effector toxins
Rima Soli, Belhassen Kaabi, Mourad Barhoumi, Mohamed El-Ayeb, Najet Srairi-Abid
BMC Pharmacology 2009, 9:4 (10March2009)
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Research article
The mode of action of dimeticone 4% lotion against head lice, Pediculus capitis
Ian F Burgess
BMC Pharmacology 2009, 9:3 (20February2009)
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AICAR activates the pluripotency transcriptional network in embryonic stem cells and induces KLF4 and KLF2 expression in fibroblasts
Luigi Adamo, Yuzhi Zhang, Guillermo Garca-Cardea
BMC Pharmacology 2009, 9:2 (12February2009)
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Conformational changes in 7 acetylcholine receptors underlying allosteric modulation by divalent cations
James T McLaughlin, Sean C Barron, Jennifer A See, Robert L Rosenberg
BMC Pharmacology 2009, 9:1 (13January2009)
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Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000
Zhan-Guo Gao, Kai Ye, Anik Gblys, Adriaan P IJzerman, Kenneth A Jacobson
BMC Pharmacology 2008, 8:20 (12December2008)
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Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells
Qing-Wen Chen, Lars Edvinsson, Cang-Bao Xu
BMC Cell Biology 2009, 10:52 (3July2009)
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Research
Effects of triptolide from Radix Tripterygium wilfordii (Leigongteng) on cartilage cytokines and transcription factor NF-kappaB: a study on induced arthritis in rats
Cheng Xiao, Jing Zhou, Yinghui He, Hongwei Jia, Linhua Zhao, Ning Zhao, Aiping Lu
Chinese Medicine 2009, 4:13 (2July2009)
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Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes
Haijun Zhang, Wenjun Xin, Patrick M Dougherty
Molecular Pain 2009, 5:36 (1July2009)
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Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain
Leonardo Guasti, Denise Richardson, Maulik Jhaveri, Khalil Eldeeb, David A Barrett, Maurice R Elphick, Stephen PH Alexander, David A Kendall, Gregory J Michael, Victoria Chapman
Molecular Pain 2009, 5:35 (1July2009)
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Research article
Anti-tumor effect of Liqi, a traditional Chinese medicine prescription, in tumor bearing mice
Deng-Bo Ji, Jia Ye, Yi-Min Jiang, Bo-Wen Qian
BMC Complementary and Alternative Medicine 2009, 9:20 (1July2009)
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Research article
A retrospective study on the impact of comorbid depression or anxiety on healthcare resource use and costs among diabetic neuropathy patients
Luke Boulanger, Yang Zhao, Yanjun Bao, Mason W Russell
BMC Health Services Research 2009, 9:111 (30June2009)
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The prosurvival role of autophagy in Resveratrol-induced cytotoxicity in human U251 glioma cells
Jun Li, Zhenghong Qin, Zhongqin Liang
BMC Cancer 2009, 9:215 (30June2009)
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Role of Accelerated Segment Switch in Exons to Alter Targeting (ASSET) in the Molecular Evolution of Snake Venom Proteins
Robin Doley, Stephen P Mackessy, R Manjunatha Kini
BMC Evolutionary Biology 2009, 9:146 (30June2009)
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Effect of questionnaire structure on recall of drug utilization in a population of university students
Helena Gama, Sofia Correia, Nuno Lunet
BMC Medical Research Methodology 2009, 9:45 (29June2009)
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Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer
Glen A Doherty, Sinead M Byrne, Eamonn S Molloy, Vikrum Malhotra, Sandra C Austin, Elaine W Kay, Frank E Murray, Desmond J Fitzgerald
BMC Cancer 2009, 9:207 (26June2009)
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