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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Tim Sands PhD
Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents.
BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus and Google Scholar.
BMC Pharmacology 2009, 9 :15
The neuromuscular blocker rapacuronium decreases the affinity of acetylcholine for all muscarinic receptor subtypes under equilibrium conditions, but increases the rate of acetylcholine binding to muscarinic receptors 1, 3 and 5 at lower concentrations.
BMC Pharmacology 2009, 9 :13
The psychotropic drug spiperone is a novel Wnt inhibitor that blocks canonical Wnt signaling by increasing intracellular calcium levels and is a candidate for use in the management of cancers that have aberrant Wnt signaling.
BMC Pharmacology 2009, 9 :12
A drug delivery vehicle that uses the non-toxic heavy chain of botulinum neurotoxin-A to gain entry to neurons via endocytosis could rescue synapses poisoned by botox, once an effective antidote is found.
Latest supplements published in BMC Pharmacology
Volume 9 Suppl 2
Meeting abstracts
Graz, Austria. 19-21 November 2009
Latest articles published in BMC Pharmacology [more info ]
Database
BIAdb: A curated database of benzylisoquinoline alkaloids Deepak Singla, Arun Sharma, Jasjit Kaur, Bharat Panwar, Gajendra P S Raghava BMC Pharmacology 2010, 10 :4 (5 March 2010) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Hypothesis
Targeting ligand-gated ion channels in Neurology and Psychiatry: is pharmacological promiscuity an obstacle or an opportunity?
Matt T Bianchi, Emmanuel J Botzolakis BMC Pharmacology 2010, 10 :3 (2 March 2010) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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Mitochondria-targeted antioxidant effects of S(-) and R(+) pramipexole Giulia Ferrari-Toninelli, Giuseppina Maccarinelli, Daniela Uberti, Erich Buerger, Maurizio Memo BMC Pharmacology 2010, 10 :2 (5 February 2010) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Antinociceptive effect of geranylgeraniol and 6 ,7 -dihydroxyvouacapan-17 -oate methyl ester isolated from Pterodon pubescens Benth Humberto M Spindola, Leila Servat, Carina Denny, Rodney AF Rodrigues, Marcos N Eberlin, Elaine Cabral, Ilza MO Sousa, Jorge Y Tamashiro, Jo o E Carvalho, Mary A Foglio BMC Pharmacology 2010, 10 :1 (7 January 2010) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors Jan Jakub k, Alena Rand kov , Esam E El-Fakahany, Vladim r Dole al BMC Pharmacology 2009, 9 :15 (28 December 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Differential regulation of muscarinic M1 receptors by orthosteric and allosteric ligands Christopher N Davis, Stefania Risso Bradley, Hans H Schiffer, Mikael Friberg, Kristian Koch, Bo-Ragnar Tolf, Douglas W Bonhaus, Jelveh Lameh BMC Pharmacology 2009, 9 :14 (2 December 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Spiperone enhances intracellular calcium level and inhibits the Wnt signaling pathway Desheng Lu, Dennis A Carson BMC Pharmacology 2009, 9 :13 (30 November 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
An efficient drug delivery vehicle for botulism countermeasure Peng Zhang, Radharaman Ray, Bal Ram Singh, Dan Li, Michael Adler, Prabhati Ray BMC Pharmacology 2009, 9 :12 (27 October 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Evaluation of molecular descriptors for antitumor drugs with respect to noncovalent binding to DNA and antiproliferative activity Jos Portugal BMC Pharmacology 2009, 9 :11 (16 September 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells Audun O Vik-Mo, Johan Fern , Silje Skrede, Vidar M Steen BMC Pharmacology 2009, 9 :10 (29 August 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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