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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Danielle Burgess PhD
Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents.
BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.
BMC Pharmacology 2009, 9 :12
A drug delivery vehicle that uses the non-toxic heavy chain of botulinum neurotoxin-A to gain entry to neurons via endocytosis could rescue synapses poisoned by botox, once an effective antidote is found.
BMC Pharmacology 2009, 9 :10
Amphiphilic psychotropic drugs stimulate cellular lipid biosynthesis and concomitantly upregulate mRNA levels of key genes in reverse cholesterol transport and lipid efflux in cultured human central nervous system and liver cells.
BMC Pharmacology 2009, 9 :9
A peptide selected for its ability to inhibit regulator of G protein signalling 4 (RGS4) binds covalently to cysteines through disuphide bridges, showing some selectivity for RGS4 and blocking the interaction with its Galpha subunit target
Volume 9 Suppl 1
Meeting abstracts
Regensburg, Germany. 19
more info ]
Research article
An efficient drug delivery vehicle for botulism countermeasure Peng Zhang, Radharaman Ray, Bal Ram Singh, Dan Li, Michael Adler, Prabhati Ray BMC Pharmacology 2009, 9 :12 (27 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Evaluation of molecular descriptors for antitumor drugs with respect to noncovalent binding to DNA and antiproliferative activity Jos BMC Pharmacology 2009, 9 :11 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells Audun O Vik-Mo, Johan Fern BMC Pharmacology 2009, 9 :10 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen Rebecca A Roof, David L Roman, Samuel T Clements, Katarzyna Sobczyk-Kojiro, Levi L Blazer, Shodai Ota, Henry I Mosberg, Richard R Neubig BMC Pharmacology 2009, 9 :9 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models Nancy Lee, Chelsey L Woodrum, Alison M Nobil, Aubrey E Rauktys, Michael P Messina, Sandra L Dabora BMC Pharmacology 2009, 9 :8 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes Rong Shi, Chuan-Chin Huang, Robert S Aronstam, Nuran Ercal, Adam Martin, Yue-Wern Huang BMC Pharmacology 2009, 9 :7 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Haloperidol changes mRNA expression of a QKI splice variant in human astrocytoma cells Lin Jiang, Peter Saetre, Elena Jazin, Eva Lindholm Carlstr BMC Pharmacology 2009, 9 :6 (31 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Preferential uptake of the non steroid anti-inflammatory drug diclofenac into inflamed tissues after a single oral dose in rats A Schweitzer, N Hasler-Nguyen, J Zijlstra BMC Pharmacology 2009, 9 :5 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Bioinformatic characterizations and prediction of K+ and Na+ ion channels effector toxins Rima Soli, Belhassen Kaabi, Mourad Barhoumi, Mohamed El-Ayeb, Najet Srairi-Abid BMC Pharmacology 2009, 9 :4 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The mode of action of dimeticone 4% lotion against head lice, Pediculus capitis Ian F Burgess BMC Pharmacology 2009, 9 :3 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
The ischemic preconditioning effect of adenosine in patients with ischemic heart disease Bita Sadigh, Miguel Quintana, Christer Sylven, Margareta Berglund, Lars Ake Brodin Cardiovascular Ultrasound 2009, 7 :52 (5 [Abstract ] [Provisional PDF ]
Research
Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact Mushfiquddin Khan, Yeong-Bin Im, Anadakumar Shunmugavel, Anne G Gilg, Ramanpreet KAUR Dhindsa, Avtar K Singh, Inderjit Singh Journal of Neuroinflammation 2009, 6 :32 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Dose dependent effect of statins on postoperative atrial fibrillation after cardiac surgery among patients treated with beta blockers Salima Mithani, Muhammad S. Akbar, Deborah J Johnson, Michael Kuskowski, Katherine K Apple, Jana Bonawitz-Conlin, Herbert B Ward, Rosemary F Kelly, Edward O McFalls, Hanna E Bloomfield, Jian-Ming Li, Selcuk Adabag Journal of Cardiothoracic Surgery 2009, 4 :61 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Short Report
An analysis of abstracts presented to the College on Problems of Drug Dependence meeting and subsequent publication in peer review journals Juan Carlos Valderrama-Zurian, Maxima Bolanos-Pizarro, Francisco Jesus Bueno-Canigral, F. Javier Alvarez, Jose Antonio Ontalba-Ruiperez, Rafael Aleixandre-Benavent Substance Abuse Treatment, Prevention, and Policy 2009, 4 :19 (4 [Abstract ] [Provisional PDF ]
Research
Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels Annika Malkia, Maria Pertusa, Gregorio Fernandez-Ballester, Antonio Ferrer-Montiel, Felix Viana Molecular Pain 2009, 5 :62 (3 [Abstract ] [Provisional PDF ]
Research article
ACR70-disease activity score remission achievement from switches between all the available biological agents in rheumatoid arthritis: a systematic review of the literature Stefano Alivernini, Antonella Laria, Elisa Gremese, Angelo Zoli, Gianfranco Ferraccioli Arthritis Research & Therapy 2009, 11 :R163 (3 [Abstract ] [Provisional PDF ]
Case report
Radiation recall dermatitis with soft tissue necrosis following pemetrexed therapy: a case report Christian Spirig, Aurelius Omlin, Giannicola D'Addario, Klaus-Dieter Loske, Philipp Esenwein, Jan HENNING Geismar, Thomas Ruhstaller Journal of Medical Case Reports 2009, 3 :93 (2 [Abstract ] [Provisional PDF ]
Research
The bioavailability and airway clearance of the steroid component of budesonide/formoterol and salmeterol/fluticasone after inhaled administration in patients with COPD and healthy subjects: A randomized controlled trial Chris Dalby, Thomasz Powlanowski, Thomas Larsson, Lars Borgstrom, Staffan Edsbacker, Tim W Harrison Respiratory Research 2009, 10 :104 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
EM011 activates a survivin-dependent apoptotic program in human non-small cell lung cancer cells Prasanthi Karna, Star Sharp, Clayton Yates, Satya Prakash, Ritu Aneja Molecular Cancer 2009, 8 :93 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
eCAT: Online electronic lab notebook for scientific research Nigel H Goddard, Rory Macneil, Jonathan Ritchie Automated Experimentation 2009, 1 :4 (29 [Abstract ] [Provisional PDF ]
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