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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Tim Sands PhD
Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents.
BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus and Google Scholar.
Featured articles
BMC Pharmacology 2009, 9 :15
The neuromuscular blocker rapacuronium decreases the affinity of acetylcholine for all muscarinic receptor subtypes under equilibrium conditions, but increases the rate of acetylcholine binding to muscarinic receptors 1, 3 and 5 at lower concentrations.
BMC Pharmacology 2009, 9 :13
The psychotropic drug spiperone is a novel Wnt inhibitor that blocks canonical Wnt signaling by increasing intracellular calcium levels and is a candidate for use in the management of cancers that have aberrant Wnt signaling.
BMC Pharmacology 2009, 9 :12
A drug delivery vehicle that uses the non-toxic heavy chain of botulinum neurotoxin-A to gain entry to neurons via endocytosis could rescue synapses poisoned by botox, once an effective antidote is found.
Volume 9 Suppl 2
Meeting abstracts
Graz, Austria. 19-21 November 2009
Volume 9 Suppl 1
Meeting abstracts
Regensburg, Germany. 19
more info ]
Research article
Mitochondria-targeted antioxidant effects of S(-) and R(+) pramipexole Giulia Ferrari-Toninelli, Giuseppina Maccarinelli, Daniela Uberti, Erich Buerger, Maurizio Memo BMC Pharmacology 2010, 10 :2 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Antinociceptive effect of geranylgeraniol and 6Pterodon pubescens Benth Humberto M Spindola, Leila Servat, Carina Denny, Rodney AF Rodrigues, Marcos N Eberlin, Elaine Cabral, Ilza MO Sousa, Jorge Y Tamashiro, Jo BMC Pharmacology 2010, 10 :1 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors Jan Jakub BMC Pharmacology 2009, 9 :15 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Differential regulation of muscarinic M1 receptors by orthosteric and allosteric ligands Christopher N Davis, Stefania Risso Bradley, Hans H Schiffer, Mikael Friberg, Kristian Koch, Bo-Ragnar Tolf, Douglas W Bonhaus, Jelveh Lameh BMC Pharmacology 2009, 9 :14 (2 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Spiperone enhances intracellular calcium level and inhibits the Wnt signaling pathway Desheng Lu, Dennis A Carson BMC Pharmacology 2009, 9 :13 (30 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
An efficient drug delivery vehicle for botulism countermeasure Peng Zhang, Radharaman Ray, Bal Ram Singh, Dan Li, Michael Adler, Prabhati Ray BMC Pharmacology 2009, 9 :12 (27 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Evaluation of molecular descriptors for antitumor drugs with respect to noncovalent binding to DNA and antiproliferative activity Jos BMC Pharmacology 2009, 9 :11 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells Audun O Vik-Mo, Johan Fern BMC Pharmacology 2009, 9 :10 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen Rebecca A Roof, David L Roman, Samuel T Clements, Katarzyna Sobczyk-Kojiro, Levi L Blazer, Shodai Ota, Henry I Mosberg, Richard R Neubig BMC Pharmacology 2009, 9 :9 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models Nancy Lee, Chelsey L Woodrum, Alison M Nobil, Aubrey E Rauktys, Michael P Messina, Sandra L Dabora BMC Pharmacology 2009, 9 :8 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Comparative transfection of DNA into primary and transformed mammalian cells from different lineages Rosalie Maurisse, David De Semir, Hamid Emamekhoo, Babak Bedayat, Alireza Abdolmohammadi, Hooman Parsi, Dieter C Gruenert BMC Biotechnology 2010, 10 :9 (8 [Abstract ] [Provisional PDF ]
Research
Facilitation of synaptic transmission and pain responses
by CGRP in the amygdala of normal rats Jeong S Han, Hita Adwanikar, Zhen Li, Guangchen Ji, Volker Neugebauer Molecular Pain 2010, 6 :10 (8 [Abstract ] [Provisional PDF ]
Research article
Food seeking in spite of harmful consequences is under prefrontal cortical noradrenergic control Emanuele Claudio Latagliata, Enrico Patrono, Stefano Puglisi-Allegra, Rossella Ventura BMC Neuroscience 2010, 11 :15 (8 [Abstract ] [Provisional PDF ]
Research
Hypoglycemia induced changes in cholinergic receptor expression in the cerebellum of diabetic rats Sherin Antony, Peeyush T Kumar, Jobin Mathew, Anju T R, C S Paulose Journal of Biomedical Science 2010, 17 :7 (5 [Abstract ] [Provisional PDF ]
Short report
CpG oligodeoxyribonucleotides protect mice from Burkholderia pseudomallei but not Francisella tularensis Schu S4 aerosols. David A. Rozak, Herbert C. Gelhaus, Mark Smith, Mojgan Zadeh, Louis Huzella, David Waag, Jeffrey J. Adamovicz Journal of Immune Based Therapies and Vaccines 2010, 8 :2 (5 [Abstract ] [Provisional PDF ]
Review
Ceramide and ceramide 1-phosphate in health and disease Lide Arana, Patricia Gangoiti, Alberto Ouro, Miguel Trueba, Antonio Gomez-Munoz Lipids in Health and Disease 2010, 9 :15 (5 [Abstract ] [Provisional PDF ]
Research
Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils Hannu Kankaanranta, Mirkka Janka-Junttila, Pinja Ilmarinen-Salo, Kazuhiro Ito, Ulla Jalonen, Misako Ito, Ian M Adcock, Eeva Moilanen, Xianzhi Zhang Journal of Inflammation 2010, 7 :9 (4 [Abstract ] [Provisional PDF ]
Research
Nonsteroidal Anti-Inflammatory Drugs: A survey of practices and concerns of pediatric medical and surgical specialists and a summary of available safety data Deborah M Levy, Lisa F Imundo Pediatric Rheumatology 2010, 8 :7 (4 [Abstract ] [Provisional PDF ]
Research
Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa Noemie Resseguier, Vanessa Machault, Lenaick Ollivier, Eve Orlandi-Pradines, Gaetan Texier, Bruno Pradines, Jean Gaudart, Alain Buguet, Catherine Tourette-Turgis, Christophe Rogier Malaria Journal 2010, 9 :41 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Unchanged triclabendazole kinetics after co-administration with ivermectin and methimazole: failure of its therapeutic activity against triclabendazole-resistant liver flukes Laura Ceballos, Laura Moreno, Luis Alvarez, Laura Shaw, Ian Fairweather, Carlos Lanusse BMC Veterinary Research 2010, 6 :8 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Featured articles 
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