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Volume 7 (2006) - April 2006

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Research article   Open Access Highly Accessed

Serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients

Dietrich E Lorke, Gang Lu, Eric Cho, David T Yew BMC Neuroscience 2006, 7:36 (27 April 2006)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Alzheimer's disease patients have the same pattern of 5-HT2A and 5-HT6 receptor expression in the prefrontal cortex as in normally ageing subjects, but the density of receptor-positive cells is reduced by over a third.

Research article   Open Access Highly Accessed

Neuroprotection from NMDA excitotoxic lesion by Cu/Zn superoxide dismutase gene delivery to the postnatal rat brain by a modular protein vector

Hugo Peluffo, Laia Acarin, Anna Arís, Pau González, Antoni Villaverde, Bernardo Castellano, Berta González BMC Neuroscience 2006, 7:35 (25 April 2006)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Transient expression of the antioxidant enzyme Cu/Zn superoxide dismutase (SOD), using a non-viral gene vector injected into postnatal rat brain, following excitotoxic brain injury improves functional outcome and reduces lesion volume.

Research article   Open Access

The photocurrent response of human cones is fast and monophasic

JH van Hateren, TD Lamb BMC Neuroscience 2006, 7:34 (20 April 2006)

Abstract | Full text | PDF | PubMed |  Editor’s summary

An accurate estimate of the cone photoresponse in the living human eye may be achieved using both predictions from a model of transduction or a paired-flash electroretinogram method; the photoresponse is fast and monophasic.

Research article   Open Access

Prenatal cocaine exposure alters alpha2 receptor expression in adolescent rats

Rosemarie M Booze, David R Wallace, Janelle M Silvers, Barbara J Strupp, Diane M Snow, Charles F Mactutus BMC Neuroscience 2006, 7:33 (18 April 2006)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Convulsant bicuculline modifies CNS muscarinic receptor affinity

Patricia G Schneider, Georgina Rodríguez de Lores Arnaiz BMC Neuroscience 2006, 7:32 (17 April 2006)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Crossmodal attention effects on brain responses to different stimulus classes

Wido Nager, Kaija Estorf, Thomas F Münte BMC Neuroscience 2006, 7:31 (11 April 2006)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

The role of the AFD neuron in C. elegans thermotaxis analyzed using femtosecond laser ablation

Samuel H Chung, Damon A Clark, Christopher V Gabel, Eric Mazur, Aravinthan DT Samuel BMC Neuroscience 2006, 7:30 (6 April 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Ablating individual dendrites or cell bodies of C. elegans AFD neurons by using focused femtosecond laser pulses allows discrimination between alternative models of cryophilic and thermophilic navigation.

Research article   Open Access Highly Accessed

A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis

Zhong Zhao, Dale J Lange, Andrei Voustianiouk, Donal MacGrogan, Lap Ho, Jason Suh, Nelson Humala, Meenakshisundaram Thiyagarajan, Jun Wang, Giulio M Pasinetti BMC Neuroscience 2006, 7:29 (3 April 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

In SOD1-G93A mouse models of amyotrophic lateral sclerosis, a ketogenic diet may prolong motor function through increased ATP production and protection of motor neurons from certain mitochondrial toxins.


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