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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good PhD
Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of chromatin, replication, recombination, mutation, repair, transcription, translation and RNA processing and function.
BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Molecular Biology 2009, 10 :103
A putative regulatory sequence has been characterized within exon 6A of the vascular endothelial growth factor (VEGF) mRNA, which is involved in alternative splicing of this exon and regulates the expression levels of the isoforms of VEGF.
BMC Molecular Biology 2009, 10 :101
The hypoxia-tolerant grass carp has two CITED3 genes whose promoters bind HIF-1 as they are induced by hypoxia in the liver and kidneys, and whose products are co-transcriptional regulators that interact with p300 and affect HIF-1 activity.
BMC Molecular Biology 2009, 10 :89
Monomers of the transcriptional regulator C-terminal binding protein 2 (CtBP2) bind competitively to the PLDLS-motif cofactor zinc-finger E-box binding homeobox (ZEB) and the histone deacetylase HDAC2, but do not mediate transcriptional repression, while dimers which bind both are functional.
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Research article
Sequence-dependent DNA helical rise and nucleosome stability Francesco Pedone, Daniele Santoni BMC Molecular Biology 2009, 10 :105 (27 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Arsenic transport by zebrafish aquaglyceroporins Mohamad Hamdi, Marco A Sanchez, Lauren C Beene, Qianyong Liu, Scott M Landfear, Barry P Rosen, Zijuan Liu BMC Molecular Biology 2009, 10 :104 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of an exonic splicing silencer in exon 6A of the human VEGF gene Rui Wang, Ronald G Crystal, Neil R Hackett BMC Molecular Biology 2009, 10 :103 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The sterol carrier protein 2/3-oxoacyl-CoA thiolase (SCPx) is involved in cholesterol uptake in the midgut of Spodoptera litura : gene cloning, expression, localization and functional analyses Xing-Rong Guo, Si-Chun Zheng, Lin Liu, Qi-Li Feng BMC Molecular Biology 2009, 10 :102 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Functional characterization of two CITED3 homologs (gcCITED3a and gcCITED3b) in the hypoxia-tolerant grass carp, Ctenopharyngodon idellus Patrick KS Ng, Sung-Kay Chiu, Theresa FN Kwong, Richard MK Yu, Minnie ML Wong, Richard YC Kong BMC Molecular Biology 2009, 10 :101 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Evaluation of real-time PCR endogenous control genes for analysis of gene expression in bovine endometrium Caroline G Walker, Susanne Meier, Murray D Mitchell, John R Roche, Mathew Littlejohn BMC Molecular Biology 2009, 10 :100 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae Marie-Ange Teste, Manon Duquenne, Jean M Fran BMC Molecular Biology 2009, 10 :99 (30 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
RAD51 paralogs promote homology-directed repair at diversifying immunoglobulin V regions Ellen C Ordinario, Munehisa Yabuki, Priya Handa, W Jason Cummings, Nancy Maizels BMC Molecular Biology 2009, 10 :98 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Preliminary molecular characterization of the human pathogen Angiostrongylus cantonensis Hualiang He, Mei Cheng, Xiao Yang, Jinxiu Meng, Ai He, Xiaoying Zheng, Zhuoya Li, Pengjuan Guo, Zhihua Pan, Ximei Zhan BMC Molecular Biology 2009, 10 :97 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Dual effect of a single nucleotide polymorphism in the first intron of the porcine Secreted phosphoprotein 1 gene: allele-specific binding of C/EBP beta and activation of aberrant splicing Eduard Mur BMC Molecular Biology 2009, 10 :96 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
A panel of microsatellites to individually identify leopards and its application to leopard monitoring in human dominated landscapes Samrat Mondol, Navya R., Vidya Athreya, Kartik Sunagar, Velu MANI Selvaraj, Uma Ramakrishnan BMC Genetics 2009, 10 :79 (4 [Abstract ] [Provisional PDF ]
Research article
Signalling with retinoids in the human lung: validation of new tools for the expression study of retinoid receptors Stephane Poulain, Stephanie Lacomme, Shyue-Fang Battaglia-Hsu, Stanislas du Manoir, Lydia Brochin, Jean-Michel Vignaud, Nadine Martinet BMC Cancer 2009, 9 :423 (4 [Abstract ] [Provisional PDF ]
Research article
Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs Song Li, Edward A Mead, Shaohui Liang, Zhijian Tu BMC Genomics 2009, 10 :581 (4 [Abstract ] [Provisional PDF ]
Review
Role of host genetics in fibrosis Georgina L Hold, Paraskevi Untiveros, Karin A Saunders, Emad M El-Omar Fibrogenesis & Tissue Repair 2009, 2 :6 (4 [Abstract ] [Provisional PDF ]
Methodology article
Simultaneous mutation detection of three homoeologous genes in wheat by High Resolution Melting analysis and Mutation Surveyor Chongmei Dong, Kate Vincent, Peter Sharp BMC Plant Biology 2009, 9 :143 (4 [Abstract ] [Provisional PDF ]
Methodology article
Temperature Switch PCR (TSP): Robust assay design for reliable amplification and genotyping of SNPs Tania Tabone, Diane E Mather, Matthew J Hayden BMC Genomics 2009, 10 :580 (3 [Abstract ] [Provisional PDF ]
Research article
Efficacy of plasma vascular endothelial growth factor in monitoring first-line chemotherapy in patients with advanced non-small cell lung cancer Sachin Kumar, Randeep Guleria, Vikas Singh, Alok C Bharti, Anant Mohan, Bhudev C Das BMC Cancer 2009, 9 :421 (3 [Abstract ] [Provisional PDF ]
Research
The Universal Plausibility Metric (UPM) & Principle (UPP) David L. Abel Theoretical Biology and Medical Modelling 2009, 6 :27 (3 [Abstract ] [Provisional PDF ]
Research
Non-imprinted allele-specific DNA methylation on human autosomes Yingying Zhang, Christian Rohde, Richard Reinhardt, Claudia Voelcker-Rehage, Albert Jeltsch Genome Biology 2009, 10 :R138 (3 [Abstract ] [Provisional PDF ]
Research
Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice Koustav Ganguly, Swapna Upadhyay, Martin Irmler, Shinji Takenaka, Katrin Pukelsheim, Johannes Beckers, Eckard Hamelmann, Holger Schulz, Tobias Stoeger Particle and Fibre Toxicology 2009, 6 :31 (2 [Abstract ] [Provisional PDF ]
Featured articles 
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