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	1. 2381 Accesses	Research article Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews Beverley J Shea, Jeremy M Grimshaw, George A Wells, Maarten Boers, Neil Andersson, Candyce Hamel, Ashley C Porter, Peter Tugwell, David Moher, Lex M Bouter BMC Medical Research Methodology 2007, 7:10 (15 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	2. 2312 Accesses	Commentary A tutorial on pilot studies: the what, why and how Lehana Thabane, Jinhui Ma, Rong Chu, Ji Cheng, Afisi Ismaila, Lorena P Rios, Reid Robson, Marroon Thabane, Lora Giangregorio, Charles H Goldsmith BMC Medical Research Methodology 2010, 10:1 (6 January 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	3. 1597 Accesses	Research article What about N? A methodological study of sample-size reporting in focus group studies Benedicte Carlsen, Claire Glenton BMC Medical Research Methodology 2011, 11:26 (11 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	4. 1491 Accesses	Research article When is it rational to participate in a clinical trial? A game theory approach incorporating trust, regret and guilt Benjamin Djulbegovic, Iztok Hozo BMC Medical Research Methodology 2012, 12:85 (22 June 2012) Abstract \| Full text \| PDF \| PubMed
	5. 1416 Accesses	Research article The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews Penny Whiting, Anne WS Rutjes, Johannes B Reitsma, Patrick MM Bossuyt, Jos Kleijnen BMC Medical Research Methodology 2003, 3:25 (10 November 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	6. 1380 Accesses	Commentary The case study approach Sarah Crowe, Kathrin Cresswell, Ann Robertson, Guro Huby, Anthony Avery, Aziz Sheikh BMC Medical Research Methodology 2011, 11:100 (27 June 2011) Abstract \| Full text \| PDF \| PubMed
	7. 1312 Accesses	Correspondence What is a pilot or feasibility study? A review of current practice and editorial policy Mubashir Arain, Michael J Campbell, Cindy L Cooper, Gillian A Lancaster BMC Medical Research Methodology 2010, 10:67 (16 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	8. 1289 Accesses	Correspondence How to do a grounded theory study: a worked example of a study of dental practices Alexandra Sbaraini, Stacy M Carter, R Evans, Anthony Blinkhorn BMC Medical Research Methodology 2011, 11:128 (9 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	9. 1230 Accesses	Research article Effectiveness of Pilates exercise in treating people with chronic low back pain: a systematic review of systematic reviews Cherie Wells, Gregory S Kolt, Paul Marshall, Bridget Hill, Andrea Bialocerkowski BMC Medical Research Methodology 2013, 13:7 (19 January 2013) Abstract \| Full text \| PDF \| PubMed
	10. 1168 Accesses	Research article Methods for the thematic synthesis of qualitative research in systematic reviews James Thomas, Angela Harden BMC Medical Research Methodology 2008, 8:45 (10 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	11. 1082 Accesses	Research article The stepped wedge trial design: a systematic review Celia A Brown, Richard J Lilford BMC Medical Research Methodology 2006, 6:54 (8 November 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	12. 1042 Accesses	Debate Methods for the synthesis of qualitative research: a critical review Elaine Barnett-Page, James Thomas BMC Medical Research Methodology 2009, 9:59 (11 August 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	13. 1011 Accesses	Research article A systematic review of the content of critical appraisal tools Persis Katrak, Andrea E Bialocerkowski, Nicola Massy-Westropp, VS Saravana Kumar, Karen A Grimmer BMC Medical Research Methodology 2004, 4:22 (16 September 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Tools for the critical appraisal of research reports often lack information on their development and there is no gold standard for any type of study design.
	14. 968 Accesses	Research article Meta-analysis: Neither quick nor easy Nancy G Berman, Robert A Parker BMC Medical Research Methodology 2002, 2:10 (9 August 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	15. 968 Accesses	Research article Parametric versus non-parametric statistics in the analysis of randomized trials with non-normally distributed data Andrew J Vickers BMC Medical Research Methodology 2005, 5:35 (3 November 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary Analysis of simulated data reveals that ANCOVA should be the preferred method for analyzing randomized trials with pre-test and post-test measures and non-normally distributed data, but in cases with extreme skew, Mann-Whitney was preferred.
	16. 919 Accesses	Research article Estimating the mean and variance from the median, range, and the size of a sample Stela Hozo, Benjamin Djulbegovic, Iztok Hozo BMC Medical Research Methodology 2005, 5:13 (20 April 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Distribution free estimation of mean and variance for trials where the median, range and size are all that is reported should enable inclusion of more trials in meta-analysis.
	17. 845 Accesses	Research article Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio Aluísio JD Barros, Vânia N Hirakata BMC Medical Research Methodology 2003, 3:21 (20 October 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	18. 838 Accesses	Research article Methodology in conducting a systematic review of systematic reviews of healthcare interventions Valerie Smith, Declan Devane, Cecily M Begley, Mike Clarke BMC Medical Research Methodology 2011, 11:15 (3 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Locating and retrieving relevant literature when conducting a systematic review is challenging but a number of possible solutions are available which may help clinicians appraise published reviews systematically and aid evidence-based clinical decision-making.
	19. 799 Accesses	Debate Qualitative description – the poor cousin of health research? Mette Neergaard, Frede Olesen, Rikke Andersen, Jens Sondergaard BMC Medical Research Methodology 2009, 9:52 (16 July 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	20. 727 Accesses	Correspondence Reducing bias through directed acyclic graphs Ian Shrier, Robert W Platt BMC Medical Research Methodology 2008, 8:70 (30 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A simple 6-step approach to applying direct acyclic graphs in biomedical research may aid researchers to more accurately identify and adjust for multiple confounding effects and reduce the degree of bias better than traditional methods.
	21. 726 Accesses	Commentary Sample size calculations for cluster randomised controlled trials with a fixed number of clusters Karla Hemming, Alan J Girling, Alice J Sitch, Jennifer Marsh, Richard J Lilford BMC Medical Research Methodology 2011, 11:102 (30 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	22. 704 Accesses	Research article The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials David Moher, Kenneth F Schulz, Douglas G Altman BMC Medical Research Methodology 2001, 1:2 (20 April 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23. 656 Accesses	Debate Conducting a meta-ethnography of qualitative literature: Lessons learnt Salla Atkins, Simon Lewin, Helen Smith, Mark Engel, Atle Fretheim, Jimmy Volmink BMC Medical Research Methodology 2008, 8:21 (16 April 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Although meta-ethnography offers a useful methodology for the synthesis of qualitative research, its application to the study of adherence to tuberculosis treatment highlights a number of methodological and epistemological challenges which must still be addressed.
	24. 595 Accesses	Research article The Hawthorne Effect: a randomised, controlled trial Rob McCarney, James Warner, Steve Iliffe, Robbert van Haselen, Mark Griffin, Peter Fisher BMC Medical Research Methodology 2007, 7:30 (3 July 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	25. 557 Accesses	Debate Pragmatic controlled clinical trials in primary care: the struggle between external and internal validity Marshall Godwin, Lucia Ruhland, Ian Casson, Susan MacDonald, Dianne Delva, Richard Birtwhistle, Miu Lam, Rachelle Seguin BMC Medical Research Methodology 2003, 3:28 (22 December 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central