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Prognostics and diagnostics/biomarkers Section edited by Patrick Tan

This section considers studies on the use of genomic markers to diagnose, classify, or predict the risk or prognosis of human disease.

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1.

Research article   Open Access

An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer

Jinping Jia, Hemang Parikh, Wenming Xiao, Jason W Hoskins, Holger Pflicke, Xuelu Liu, Irene Collins, Weiyin Zhou, Zhaoming Wang, John Powell, Snorri S Thorgeirsson, Udo Rudloff, Gloria M Petersen, Laufey T Amundadottir BMC Medical Genomics 2013, 6:33 (22 September 2013)

Abstract | Full text | PDF | PubMed

2.

Case report   Open Access

De novo frameshift mutation in ASXL3 in a patient with global developmental delay, microcephaly, and craniofacial anomalies

Darrell L Dinwiddie, Sarah E Soden, Carol J Saunders, Neil A Miller, Emily G Farrow, Laurie D Smith, Stephen F Kingsmore BMC Medical Genomics 2013, 6:32 (17 September 2013)

Abstract | Provisional PDF | PubMed

3.

Research article   Open Access

Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia

Domenica Ronchetti, Laura Mosca, Giovanna Cutrona, Giacomo Tuana, Massimo Gentile, Sonia Fabris, Luca Agnelli, Gabriella Ciceri, Serena Matis, Carlotta Massucco, Monica Colombo, Daniele Reverberi, Anna Recchia, Sabrina Bossio, Massimo Negrini, Pierfrancesco Tassone, Fortunato Morabito, Manlio Ferrarini, Antonino Neri BMC Medical Genomics 2013, 6:27 (3 September 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

Research article   Open Access

Genetic lineages of undifferentiated-type gastric carcinomas analysed by unsupervised clustering of genomic DNA microarray data

Ayano Sonoda, Ken-ichi Mukaisho, Takahisa Nakayama, Vo Thi Diem, Takanori Hattori, Akira Andoh, Yoshihide Fujiyama, Hiroyuki Sugihara BMC Medical Genomics 2013, 6:25 (19 July 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

Research article   Open Access

Serum microRNAs profile from genome-wide serves as a fingerprint for diagnosis of acute myocardial infarction and angina pectoris

Chunjian Li, Zhijuan Fang, Ting Jiang, Qiu Zhang, Chao Liu, Chenyu Zhang, Yang Xiang BMC Medical Genomics 2013, 6:16 (4 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

6.

Research article   Open Access

Analysis of a gene co-expression network establishes robust association between Col5a2 and ischemic heart disease

Francisco Azuaje, Lu Zhang, Céline Jeanty, Sarah-Lena Puhl, Sophie Rodius, Daniel R Wagner BMC Medical Genomics 2013, 6:13 (10 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

7.

Research article   Open Access

Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines

Andreas Schlicker, Garry Beran, Christine M Chresta, Gael McWalter, Alison Pritchard, Susie Weston, Sarah Runswick, Sara Davenport, Kerry Heathcote, Denis Alferez Castro, George Orphanides, Tim French, Lodewyk FA Wessels BMC Medical Genomics 2012, 5:66 (31 December 2012)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access

Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case–control study

Yi Guo, Yi Gong, Chunming Pan, Yanrong Qian, Guochao Shi, Qijian Cheng, Qingyun Li, Lei Ren, Qiuling Weng, Yi Chen, Ting Cheng, Liang Fan, Zhihong Jiang, Huanying Wan BMC Medical Genomics 2012, 5:64 (26 December 2012)

Abstract | Full text | PDF | PubMed

9.

Research article   Open Access

A whole blood gene expression-based signature for smoking status

Philip Beineke, Karen Fitch, Heng Tao, Michael R Elashoff, Steven Rosenberg, William E Kraus, James A Wingrove, PREDICT Investigators BMC Medical Genomics 2012, 5:58 (3 December 2012)

Abstract | Full text | PDF | PubMed

10.

Research article   Open Access

An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node involvement but with poor prognosis

Françoise Bonnet, Mickael Guedj, Natalie Jones, Sana Sfar, Véronique Brouste, Nabila Elarouci, Guillaume Banneau, Béatrice Orsetti, Charlotte Primois, Christine Tunon de Lara, Marc Debled, Isabelle de Mascarel, Charles Theillet, Nicolas Sévenet, Aurélien de Reynies, Gaëtan MacGrogan, Michel Longy BMC Medical Genomics 2012, 5:54 (27 November 2012)

Abstract | Full text | PDF | PubMed

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