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1.
1843 Accesses
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Molecular prediction for atherogenic risks across different cell types of leukocytes
Feng Cheng, Ellen C Keeley, Jae K Lee BMC Medical Genomics 2012, 5:2 (13 January 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
An new set of 56 gene expression biomarkers could be used to predict early atherosclerosis from leukocytes before the symptoms of heart disease have developed, and this test can be further refined to identify very high risk patients.
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2.
897 Accesses
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The role of disease characteristics in the ethical debate on personal genome testing
Eline M Bunnik, Maartje HN Schermer, A CECILE JW Janssens BMC Medical Genomics 2012, 5:4 (19 January 2012)
Abstract | Provisional PDF
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3.
887 Accesses
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Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
Douglas B Kell BMC Medical Genomics 2009, 2:2 (8 January 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Douglas Kell reviews the role of iron-catalysed free radicals in disease, which underpin the behavior of many physiological and pathological processes, and considers the need for better understanding using an integrative, systems-level approach.
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4.
623 Accesses
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An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma
Zhaohui Luo, Liyang Zhang, Zheng Li, Xiayu Li, Gang Li, Haibo Yu, Chen Jiang, Yafei Dai, Xiaofang Guo, Juanjuan Xiang, Guiyuan Li BMC Medical Genomics 2012, 5:3 (19 January 2012)
Abstract | Provisional PDF
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5.
621 Accesses
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Global analysis of DNA methylation in early-stage liver fibrosis
Yoko Komatsu, Tsuyoshi Waku, Naoya Iwasaki, Wakana Ono, Chie Yamaguchi, Junn Yanagisawa BMC Medical Genomics 2012, 5:5 (27 January 2012)
Abstract | Provisional PDF
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6.
476 Accesses
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miRNA signature associated with outcome of gastric cancer patients following chemotherapy
Chang Hee Kim, Hark K Kim, R. Luke Rettig, Joseph Kim, Eunbyul T Lee, Olga Aprelikova, Il J Choi, David J Munroe, Jeffrey E Green BMC Medical Genomics 2011, 4:79 (23 November 2011)
Abstract | Provisional PDF
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7.
412 Accesses
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Visualization and identification of health space, based on personalized molecular phenotype and treatment response to relevant underlying biological processes
Jildau Bouwman, Jack TWE Vogels, Suzan Wopereis, Carina M Rubingh, Sabina Bijlsma, Ben van Ommen BMC Medical Genomics 2012, 5:1 (6 January 2012)
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8.
375 Accesses
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Routine use of microarray-based gene expression profiling to identify patients with low cytogenetic risk acute myeloid leukemia: accurate results can be obtained even with suboptimal samples
Diane Raingeard de la Bletiere, Odile Blanchet, Pascale Cornillet-Lefebvre, Anne Coutolleau, Laurence Baranger, Franck Genevieve, Isabelle Luquet, Mathilde Hunault-Berger, Annaelle Beucher, Aline Schmidt-Tanguy, Marc Zandecki, Yves Delneste, Norbert Ifrah, Philippe Guardiola BMC Medical Genomics 2012, 5:6 (30 January 2012)
Abstract | Provisional PDF
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9.
363 Accesses
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Identification of DNA methylation changes associated with human gastric cancer
Jung-Hoon Park, Jinah Park, Jung Kyoon Choi, Jaemyun Lyu, Min-Gyun Bae, Young-Gun Lee, Jae-Bum Bae, Dong Yoon Park, Han-Kwang Yang, Tae-You Kim, Young-Joon Kim BMC Medical Genomics 2011, 4:82 (2 December 2011)
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10.
359 Accesses
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Batch effect correction for genome-wide methylation data with Illumina Infinium platform
Zhifu Sun, High Chai, Yanhong Wu, Wendy M White, Krishna V Donkena, Christopher J Klein, Vesna D Garovic, Terry M Therneau, Jean-Pierre A Kocher BMC Medical Genomics 2011, 4:84 (16 December 2011)
Abstract | Full text | PDF | PubMed
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11.
305 Accesses
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Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus
Christopher G Bell, Andrew E Teschendorff, Vardhman K Rakyan, Alexander P Maxwell, Stephan Beck, David A Savage BMC Medical Genomics 2010, 3:33 (5 August 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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12.
291 Accesses
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Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity
Martin Kerick, Melanie Isau, Bernd Timmermann, Holger Sültmann, Ralf Herwig, Sylvia Krobitsch, Georg Schaefer, Irmgard Verdorfer, Georg Bartsch, Helmut Klocker, Hans Lehrach, Michal R Schweiger BMC Medical Genomics 2011, 4:68 (29 September 2011)
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13.
273 Accesses
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Early Peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass
Yurena Vivas, Cristina Martinez-Garcia, Adriana Izquierdo, Francisco Garcia-Garcia, Sergio Callejas, Ismael Velasco, Mark Campbell, Manuel Ros, Ana Dopazo, Joaquin Dopazo, Antonio Vidal-Puig, Gema Medina-Gomez BMC Medical Genomics 2011, 4:86 (30 December 2011)
Abstract | Provisional PDF
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14.
246 Accesses
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The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies
Catherine A McCarty, Rex L Chisholm, Christopher G Chute, Iftikhar J Kullo, Gail P Jarvik, Eric B Larson, Rongling Li, Daniel R Masys, Marylyn D Ritchie, Dan M Roden, Jeffery P Struewing, Wendy A Wolf, the eMERGE Team BMC Medical Genomics 2011, 4:13 (26 January 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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15.
239 Accesses
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Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities
Reinhold J Medina, Christina L O'Neill, Mark Sweeney, Jasenka Guduric-Fuchs, Tom A Gardiner, David A Simpson, Alan W Stitt BMC Medical Genomics 2010, 3:18 (13 May 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Medicine
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16.
237 Accesses
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MicroRNA profiling of diverse endothelial cell types
Matthew N McCall, Oliver A Kent, Jianshi Yu, Karen Fox-Talbot, Ari L Zaiman, Marc K Halushka BMC Medical Genomics 2011, 4:78 (2 November 2011)
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17.
233 Accesses
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A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors
Andrey Loboda, Michael Nebozhyn, Rich Klinghoffer, Jason Frazier, Michael Chastain, William Arthur, Brian Roberts, Theresa Zhang, Melissa Chenard, Brian Haines, Jannik Andersen, Kumiko Nagashima, Cloud Paweletz, Bethany Lynch, Igor Feldman, Hongyue Dai, Pearl Huang, James Watters BMC Medical Genomics 2010, 3:26 (30 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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18.
230 Accesses
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Identification of candidate genes linking systemic inflammation to atherosclerosis; results of a human in vivo LPS infusion study
Suthesh Sivapalaratnam, Rosienne Farrugia, Max Nieuwdorp, Cordelia F Langford, Rachel T van Beem, Stephanie Maiwald, Jaap Zwaginga, Arief Gusnanto, Nicholas A Watkins, Mieke D Trip, Willem H Ouwehand BMC Medical Genomics 2011, 4:64 (10 August 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Changes in gene expression of circulating monocytes among healthy volunteers, following stimulation of an inflammatory response by infusion of lipopolysaccharide, is able to identify candidate genes linking systemic inflammation and atherosclerosis.
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19.
208 Accesses
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"Who owns your poop?": insights regarding the intersection of human microbiome research and the ELSI aspects of biobanking and related studies
Alice K Hawkins, Kieran C O'Doherty BMC Medical Genomics 2011, 4:72 (7 October 2011)
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20.
182 Accesses
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Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer
Meng Li, Curt Balch, John S Montgomery, Mikyoung Jeong, Jae Chung, Pearlly Yan, Tim HM Huang, Sun Kim, Kenneth P Nephew BMC Medical Genomics 2009, 2:34 (8 June 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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21.
178 Accesses
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Impact of RNA degradation on gene expression profiling
Lennart Opitz, Gabriela Salinas-Riester, Marian Grade, Klaus Jung, Peter Jo, Georg Emons, B Michael Ghadimi, Tim Beißbarth, Jochen Gaedcke BMC Medical Genomics 2010, 3:36 (9 August 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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22.
177 Accesses
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Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors
Christopher A Miller, Stephen H Settle, Erik P Sulman, Kenneth D Aldape, Aleksandar Milosavljevic BMC Medical Genomics 2011, 4:34 (14 April 2011)
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23.
170 Accesses
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Deep RNA sequencing analysis of readthrough gene fusions in human prostate adenocarcinoma and reference samples
Serban Nacu, Wenlin Yuan, Zhengyan Kan, Deepali Bhatt, Celina Rivers, Jeremy Stinson, Brock A Peters, Zora Modrusan, Kenneth Jung, Somasekar Seshagiri, Thomas D Wu BMC Medical Genomics 2011, 4:11 (24 January 2011)
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24.
168 Accesses
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Gene expression in cardiac tissues from infants with idiopathic conotruncal defects
Douglas C Bittel, Merlin G Butler, Nataliya Kibiryeva, Jennifer A Marshall, Jie Chen, Gary K Lofland, James E O'Brien BMC Medical Genomics 2011, 4:1 (5 January 2011)
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25.
168 Accesses
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Gene expression during normal and FSHD myogenesis
Koji Tsumagari, Shao-Chi Chang, Michelle Lacey, Carl Baribault, Sridar V Chittur, Janet Sowden, Rabi Tawil, Gregory E Crawford, Melanie Ehrlich BMC Medical Genomics 2011, 4:67 (27 September 2011)
Abstract | Full text | PDF | PubMed
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