biomedcentral.com/bmcmedgenomics/article
Bottom,Top,Right1
  • Log on
  •   BioMed Central
  • Journals
  • Gateways
BMC Medical Genomics
official impact factor 3.69
Search for
Advanced search
  • Home
  • Articles
  • Authors
  • Reviewers
  • About this journal
  • My BMC Medical Genomics

Submit a manuscript Register Sign up for article alerts Contact us Follow us on Twitter

Explore BMC Medical Genomics

  •  Editorial Board
  •  Instructions for authors
  •  FAQ
Advertisement

Articles

  • All articles
  • Sections
  • Most viewed RSS
      • Last 30 days
      • Last year
      • All time
  • Archive
  • Supplements

Page 1 of 4

1 2 3 4  Next

 Display/download options Articles per page: 25 | 50 | 100

Display options
Download optionsHelp icon

1.

12976
Accesses

Review   Open Access Highly Accessed

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

Douglas B Kell BMC Medical Genomics 2009, 2:2 (8 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Douglas Kell reviews the role of iron-catalysed free radicals in disease, which underpin the behavior of many physiological and pathological processes, and considers the need for better understanding using an integrative, systems-level approach.

2.

5475
Accesses

Research article   Open Access Highly Accessed

PAM50 Breast Cancer Subtyping by RT-qPCR and Concordance with Standard Clinical Molecular Markers

Roy RL Bastien, Álvaro Rodríguez-Lescure, Mark TW Ebbert, Aleix Prat, Blanca Munárriz, Leslie Rowe, Patricia Miller, Manuel Ruiz-Borrego, Daniel Anderson, Bradley Lyons, Isabel Álvarez, Tracy Dowell, David Wall, Miguel Seguí, Lee Barley, Kenneth M Boucher, Emilio Alba, Lisa Pappas, Carole A Davis, Ignacio Aranda, Christiane Fauron, Inge J Stijleman, José Palacios, Antonio Antón, Eva Carrasco, Rosalía Caballero, Matthew J Ellis, Torsten O Nielsen, Charles M Perou, Mark Astill, Philip S Bernard, Miguel Martín et al. BMC Medical Genomics 2012, 5:44 (4 October 2012)

Abstract | Full text | PDF | PubMed

3.

4879
Accesses

Technical advance   Open Access Highly Accessed

Noninvasive Fetal Trisomy (NIFTY) test: an advanced noninvasive prenatal diagnosis methodology for fetal autosomal and sex chromosomal aneuploidies

Fuman Jiang, Jinghui Ren, Fang Chen, Yuqiu Zhou, Jiansheng Xie, Shan Dan, Yue Su, Jianhong Xie, Baomin Yin, Wen Su, Huakun Zhang, Wei Wang, Xianghua Chai, Linhua Lin, Hui Guo, Qiyun Li, Peipei Li, Yuying Yuan, Xiaoyu Pan, Yihan Li, Lifu Liu, Huifei Chen, Zhaoling Xuan, Shengpei Chen, Chunlei Zhang, Hongyun Zhang, Zhongming Tian, Zhengyu Zhang, Hui Jiang, Lijian Zhao, Weimou Zheng, Songgang Li, Yingrui Li, Jun Wang, Jian Wang, Xiuqing Zhang et al. BMC Medical Genomics 2012, 5:57 (1 December 2012)

Abstract | Full text | PDF | PubMed

4.

4842
Accesses

Research article   Open Access Highly Accessed

Global analysis of DNA methylation in early-stage liver fibrosis

Yoko Komatsu, Tsuyoshi Waku, Naoya Iwasaki, Wakana Ono, Chie Yamaguchi, Junn Yanagisawa BMC Medical Genomics 2012, 5:5 (27 January 2012)

Abstract | Full text | PDF | PubMed

5.

4088
Accesses

Research article   Open Access Highly Accessed

Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

Martin Kerick, Melanie Isau, Bernd Timmermann, Holger Sültmann, Ralf Herwig, Sylvia Krobitsch, Georg Schaefer, Irmgard Verdorfer, Georg Bartsch, Helmut Klocker, Hans Lehrach, Michal R Schweiger BMC Medical Genomics 2011, 4:68 (29 September 2011)

Abstract | Full text | PDF | PubMed

6.

3686
Accesses

Research article   Open Access Highly Accessed

A systematic comparison and evaluation of high density exon arrays and RNA-seq technology used to unravel the peripheral blood transcriptome of sickle cell disease

Nalini Raghavachari, Jennifer Barb, Yanqin Yang, Poching Liu, Kimberly Woodhouse, Daniel Levy, Christopher J O‘Donnell, Peter J Munson, Gregory J Kato BMC Medical Genomics 2012, 5:28 (29 June 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology

7.

3667
Accesses

Research article   Open Access Highly Accessed

A target based approach identifies genomic predictors of breast cancer patient response to chemotherapy

Robin M Hallett, Gregory Pond, John A Hassell BMC Medical Genomics 2012, 5:16 (11 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Two new gene expression signatures can predict how breast cancer tumors will respond to two of the common kinds of chemotherapy, highlighting the potential of target-based gene expression indices to predict patient response to drug therapy.

8.

3467
Accesses

Research article   Open Access Highly Accessed

The effects of MicroRNA transfections on global patterns of gene expression in ovarian cancer cells are functionally coordinated

Shubin W Shahab, Lilya V Matyunina, Christopher G Hill, Lijuan Wang, Roman Mezencev, L Walker, John F McDonald BMC Medical Genomics 2012, 5:33 (1 August 2012)

Abstract | Full text | PDF | PubMed

9.

3455
Accesses

Research article   Open Access Highly Accessed

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors

Andrey Loboda, Michael Nebozhyn, Rich Klinghoffer, Jason Frazier, Michael Chastain, William Arthur, Brian Roberts, Theresa Zhang, Melissa Chenard, Brian Haines, Jannik Andersen, Kumiko Nagashima, Cloud Paweletz, Bethany Lynch, Igor Feldman, Hongyue Dai, Pearl Huang, James Watters BMC Medical Genomics 2010, 3:26 (30 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

3345
Accesses

Research article   Open Access Highly Accessed

DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?

Nahid Turan, Mohamed F Ghalwash, Sunita Katari, Christos Coutifaris, Zoran Obradovic, Carmen Sapienza BMC Medical Genomics 2012, 5:10 (12 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Profiling of inter-individual DNA methylation differences in neonates has identified 23 genes that account for 70-87% of variance in birth weight, whilst traditional gene expression profiling identified a far smaller proportion.

11.

3193
Accesses

Research article   Open Access Highly Accessed

Batch effect correction for genome-wide methylation data with Illumina Infinium platform

Zhifu Sun, High Chai, Yanhong Wu, Wendy M White, Krishna V Donkena, Christopher J Klein, Vesna D Garovic, Terry M Therneau, Jean-Pierre A Kocher BMC Medical Genomics 2011, 4:84 (16 December 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

12.

3041
Accesses

Research article   Open Access Highly Accessed

Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities

Reinhold J Medina, Christina L O'Neill, Mark Sweeney, Jasenka Guduric-Fuchs, Tom A Gardiner, David A Simpson, Alan W Stitt BMC Medical Genomics 2010, 3:18 (13 May 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000

13.

2996
Accesses

Research article   Open Access Highly Accessed

MicroRNA profiling of diverse endothelial cell types

Matthew N McCall, Oliver A Kent, Jianshi Yu, Karen Fox-Talbot, Ari L Zaiman, Marc K Halushka BMC Medical Genomics 2011, 4:78 (2 November 2011)

Abstract | Full text | PDF | PubMed

14.

2861
Accesses

Research article   Open Access Highly Accessed

An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma

Zhaohui Luo, Liyang Zhang, Zheng Li, Xiayu Li, Gang Li, Haibo Yu, Chen Jiang, Yafei Dai, Xiaofang Guo, Juanjuan Xiang, Guiyuan Li BMC Medical Genomics 2012, 5:3 (19 January 2012)

Abstract | Full text | PDF | PubMed

15.

2701
Accesses

Research article   Open Access Highly Accessed

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

Christopher G Bell, Andrew E Teschendorff, Vardhman K Rakyan, Alexander P Maxwell, Stephan Beck, David A Savage BMC Medical Genomics 2010, 3:33 (5 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

16.

2701
Accesses

Correspondence   Open Access Highly Accessed

The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies

Catherine A McCarty, Rex L Chisholm, Christopher G Chute, Iftikhar J Kullo, Gail P Jarvik, Eric B Larson, Rongling Li, Daniel R Masys, Marylyn D Ritchie, Dan M Roden, Jeffery P Struewing, Wendy A Wolf, the eMERGE Team BMC Medical Genomics 2011, 4:13 (26 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

17.

2695
Accesses

Research article   Open Access Highly Accessed

Impact of RNA degradation on gene expression profiling

Lennart Opitz, Gabriela Salinas-Riester, Marian Grade, Klaus Jung, Peter Jo, Georg Emons, B Michael Ghadimi, Tim Beißbarth, Jochen Gaedcke BMC Medical Genomics 2010, 3:36 (9 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

2643
Accesses

Research article   Open Access Highly Accessed

Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping

Jean E Abraham, Mel J Maranian, Inmaculada Spiteri, Roslin Russell, Susan Ingle, Craig Luccarini, Helena M Earl, Paul PD Pharoah, Alison M Dunning, Carlos Caldas BMC Medical Genomics 2012, 5:19 (30 May 2012)

Abstract | Full text | PDF | PubMed

19.

2572
Accesses

Review   Open Access Highly Accessed

Completion of the swine genome will simplify the production of swine as a large animal biomedical model

Eric M Walters, Eckhard Wolf, Jeffery J Whyte, Jiude Mao, Simone Renner, Hiroshi Nagashima, Eiji Kobayashi, Jianguo Zhao, Kevin D Wells, John K Critser, Lela K Riley, Randall S Prather BMC Medical Genomics 2012, 5:55 (15 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Eric M Walters and colleagues review the pig as a large animal biomedical model and how the publication of the swine genome sequence will further advance its utility for understanding human disease, transgenesis and xenotransplantation.

20.

2388
Accesses

Research article   Open Access

Identification of genes with a correlation between copy number and expression in gastric cancer

Lei Cheng, Ping Wang, Sheng Yang, Yanqing Yang, Qing Zhang, Wen Zhang, Huasheng Xiao, Hengjun Gao, Qinghua Zhang BMC Medical Genomics 2012, 5:14 (4 May 2012)

Abstract | Full text | PDF | PubMed

21.

2386
Accesses

Research article   Open Access Highly Accessed

MicroRNA expression signature in human abdominal aortic aneurysms

Matthew C Pahl, Kimberly Derr, Gabor Gäbel, Irene Hinterseher, James R Elmore, Charles M Schworer, Thomas C Peeler, David P Franklin, John L Gray, David J Carey, Gerard Tromp, Helena Kuivaniemi BMC Medical Genomics 2012, 5:25 (15 June 2012)

Abstract | Full text | PDF | PubMed

22.

2371
Accesses

Research article   Open Access Highly Accessed

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles

Julia Tchou, Andrew V Kossenkov, Lisa Chang, Celine Satija, Meenhard Herlyn, Louise C Showe, Ellen Puré BMC Medical Genomics 2012, 5:39 (6 September 2012)

Abstract | Full text | PDF | PubMed

23.

2353
Accesses

Research article   Open Access Highly Accessed

Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival

Nicola VL Serão, Kristin R Delfino, Bruce R Southey, Jonathan E Beever, Sandra L Rodriguez-Zas BMC Medical Genomics 2011, 4:49 (7 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

24.

2324
Accesses

Research article   Open Access Highly Accessed

Exploring the oral microbiota of children at various developmental stages of their dentition in the relation to their oral health

Wim Crielaard, Egija Zaura, Annemarie A Schuller, Susan M Huse, Roy C Montijn, Bart JF Keijser BMC Medical Genomics 2011, 4:22 (4 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

2314
Accesses

Research article   Open Access Highly Accessed

Modeling microRNA-mRNA Interactions Using PLS Regression in Human Colon Cancer

Xiaohong Li, Ryan Gill, Nigel GF Cooper, Jae Yoo, Susmita Datta BMC Medical Genomics 2011, 4:44 (19 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Page 1 of 4

1 2 3 4  Next


  • Terms and Conditions
  • Privacy statement
  • Press
  • Information for advertisers
  • Jobs at BMC
  • Support
  • Contact us

© 2013 BioMed Central Ltd unless otherwise stated. Part of Springer Science+Business Media.