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	1. 34120 Accesses	Review Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases Douglas B Kell BMC Medical Genomics 2009, 2:2 (8 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Douglas Kell reviews the role of iron-catalysed free radicals in disease, which underpin the behavior of many physiological and pathological processes, and considers the need for better understanding using an integrative, systems-level approach.
	2. 8582 Accesses	Research article Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes Jac C Charlesworth, Joanne E Curran, Matthew P Johnson, Harald HH Göring, Thomas D Dyer, Vincent P Diego, Jack W Kent, Michael C Mahaney, Laura Almasy, Jean W MacCluer, Eric K Moses, John Blangero BMC Medical Genomics 2010, 3:29 (15 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Cigarette smoking influences the expression of large networks of genes within a range of functional categories including immune response, cell death, cancer, natural killer cell signaling and xenobiotic metabolism, offering insights into induced system-wide pathological processes.
	3. 7834 Accesses	Research article Multiplex ligation-dependent probe amplification for genetic screening in autism spectrum disorders: Efficient identification of known microduplications and identification of a novel microduplication in ASMT Guiqing Cai, Lisa Edelmann, Juliet E Goldsmith, Ninette Cohen, Alisa Nakamine, Jennifer G Reichert, Ellen J Hoffman, Danielle M Zurawiecki, Jeremy M Silverman, Eric Hollander, Latha Soorya, Evdokia Anagnostou, Catalina Betancur, Joseph D Buxbaum BMC Medical Genomics 2008, 1:50 (16 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Multiplex ligation-dependent probe amplification (MPLA) identifies known and novel chromosomal abnormalities in children with autism spectrum disorders and associated cognitive impairment, suggesting that MPLA has the potential to be an effective screening method for these conditions.
	4. 7230 Accesses	Research article Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus Christopher G Bell, Andrew E Teschendorff, Vardhman K Rakyan, Alexander P Maxwell, Stephan Beck, David A Savage BMC Medical Genomics 2010, 3:33 (5 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	5. 7136 Accesses	Research article The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice Nicole JW de Wit, Hanneke Bosch-Vermeulen, Philip J de Groot, Guido JEJ Hooiveld, Mechteld Bromhaar, Jenny Jansen, Michael Müller, Roelof van der Meer BMC Medical Genomics 2008, 1:14 (6 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	6. 6849 Accesses	Research article The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis Adam I Riker, Steven A Enkemann, Oystein Fodstad, Suhu Liu, Suping Ren, Christopher Morris, Yaguang Xi, Paul Howell, Brandon Metge, Rajeev S Samant, Lalita A Shevde, Wenbin Li, Steven Eschrich, Adil Daud, Jingfang Ju, Jaime Matta BMC Medical Genomics 2008, 1:13 (28 April 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	7. 6842 Accesses	Research article Biomarker expression patterns that correlate with high grade features in treatment naive, organ-confined prostate cancer Timothy J McDonnell, Nikhil S Chari, Jeong Cho-Vega, Patricia Troncoso, Xuemei Wang, Carlos E Bueso-Ramos, Kevin Coombes, Shawn Brisbay, Remigio Lopez, George Prendergast, Christopher Logothetis, Kim-Anh Do BMC Medical Genomics 2008, 1:1 (31 January 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Tissue microarray analysis of prostate cancer demonstrates strong correlations between the expression of several apoptotic or cell cycle proteins and tumor grade, which may allow the prediction of clinically aggressive behavior.
	8. 6813 Accesses	Technical advance Genotyping panel for assessing response to cancer chemotherapy Zunyan Dai, Audrey C Papp, Danxin Wang, Heather Hampel, Wolfgang Sadee BMC Medical Genomics 2008, 1:24 (11 June 2008) Abstract \| Full text \| PDF \| PubMed
	9. 6761 Accesses	Research article Whole genome identification of Mycobacterium tuberculosis vaccine candidates by comprehensive data mining and bioinformatic analyses Anat Zvi, Naomi Ariel, John Fulkerson, Jerald C Sadoff, Avigdor Shafferman BMC Medical Genomics 2008, 1:18 (28 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	10. 6479 Accesses	Research article Worldwide population differentiation at disease-associated SNPs Sean Myles, Dan Davison, Jeffrey Barrett, Mark Stoneking, Nic Timpson BMC Medical Genomics 2008, 1:22 (4 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	11. 6298 Accesses	Research article A gene signature for post-infectious chronic fatigue syndrome John W Gow, Suzanne Hagan, Pawel Herzyk, Celia Cannon, Peter O Behan, Abhijit Chaudhuri BMC Medical Genomics 2009, 2:38 (25 June 2009) Abstract \| Full text \| PDF \| PubMed
	12. 6217 Accesses	Research article A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors Andrey Loboda, Michael Nebozhyn, Rich Klinghoffer, Jason Frazier, Michael Chastain, William Arthur, Brian Roberts, Theresa Zhang, Melissa Chenard, Brian Haines, Jannik Andersen, Kumiko Nagashima, Cloud Paweletz, Bethany Lynch, Igor Feldman, Hongyue Dai, Pearl Huang, James Watters BMC Medical Genomics 2010, 3:26 (30 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	13. 6048 Accesses	Research article Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities Reinhold J Medina, Christina L O'Neill, Mark Sweeney, Jasenka Guduric-Fuchs, Tom A Gardiner, David A Simpson, Alan W Stitt BMC Medical Genomics 2010, 3:18 (13 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	14. 5924 Accesses	Research article Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer Meng Li, Curt Balch, John S Montgomery, Mikyoung Jeong, Jae Chung, Pearlly Yan, Tim HM Huang, Sun Kim, Kenneth P Nephew BMC Medical Genomics 2009, 2:34 (8 June 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	15. 5637 Accesses	Research article MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes Blanca M Herrera, Helen E Lockstone, Jennifer M Taylor, Quin F Wills, Pamela J Kaisaki, Amy Barrett, Carme Camps, Christina Fernandez, Jiannis Ragoussis, Dominique Gauguier, Mark I McCarthy, Cecilia M Lindgren BMC Medical Genomics 2009, 2:54 (18 August 2009) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Combining global microRNA and mRNA expression data indicates MiR-125a is over-expressed in the liver of hyperglycaemic rats and is a putative modulator of glucose and lipid metabolism in a rat model of type 2 diabetes.
	16. 5532 Accesses	Research article A high confidence, manually validated human blood plasma protein reference set Susann Schenk, Gary J Schoenhals, Gustavo de Souza, Matthias Mann BMC Medical Genomics 2008, 1:41 (15 September 2008) Abstract \| Full text \| PDF \| PubMed
	17. 5510 Accesses	Research article Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis Jennifer S Guimbellot, Stephen W Erickson, Tapan Mehta, Hui Wen, Grier P Page, Eric J Sorscher, Jeong S Hong BMC Medical Genomics 2009, 2:15 (25 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	18. 5442 Accesses	Research article Detailed transcriptome atlas of the pancreatic beta cell Burak Kutlu, David Burdick, David Baxter, Joanne Rasschaert, Daisy Flamez, Decio L Eizirik, Nils Welsh, Nathan Goodman, Leroy Hood BMC Medical Genomics 2009, 2:3 (15 January 2009) Abstract \| Full text \| PDF \| PubMed
	19. 5155 Accesses	Research article Prediction of HIV-1 virus-host protein interactions using virus and host sequence motifs Perry Evans, William Dampier, Lyle Ungar, Aydin Tozeren BMC Medical Genomics 2009, 2:27 (18 May 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	20. 5084 Accesses	Research article Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer Sherene Loi, Christos Sotiriou, Benjamin Haibe-Kains, Francoise Lallemand, Nelly M Conus, Martine J Piccart, Terence P Speed, Grant A McArthur BMC Medical Genomics 2009, 2:37 (24 June 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Activation of growth factor (GF) signalling contributes to the tamoxifen-insensitive estrogen receptor-positive breast cancer phenotype independent of human epidermal growth factor receptor (HER2) gene expression, suggesting an alternative therapeutic target for this aggressive disease.
	21. 4977 Accesses	Research article Robust SNP genotyping by multiplex PCR and arrayed primer extension Mohua Podder, Jian Ruan, Ben W Tripp, Zane E Chu, Scott J Tebbutt BMC Medical Genomics 2008, 1:5 (31 January 2008) Abstract \| Full text \| PDF \| PubMed
	22. 4931 Accesses	Technical advance Expression profiling with RNA from formalin-fixed, paraffin-embedded material Andrea Oberli, Vlad Popovici, Mauro Delorenzi, Anna Baltzer, Janine Antonov, Sybille Matthey, Stefan Aebi, Hans Altermatt, Rolf Jaggi BMC Medical Genomics 2008, 1:9 (19 April 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23. 4930 Accesses	Research article Deep RNA sequencing analysis of readthrough gene fusions in human prostate adenocarcinoma and reference samples Serban Nacu, Wenlin Yuan, Zhengyan Kan, Deepali Bhatt, Celina Rivers, Jeremy Stinson, Brock A Peters, Zora Modrusan, Kenneth Jung, Somasekar Seshagiri, Thomas D Wu BMC Medical Genomics 2011, 4:11 (24 January 2011) Abstract \| Full text \| PDF \| PubMed
	24. 4863 Accesses	Research article Identification of molecular pathways affected by pterostilbene, a natural dimethylether analog of resveratrol Zhiqiang Pan, Ameeta K Agarwal, Tao Xu, Qin Feng, Scott R Baerson, Stephen O Duke, Agnes M Rimando BMC Medical Genomics 2008, 1:7 (20 March 2008) Abstract \| Full text \| PDF \| PubMed
	25. 4808 Accesses	Research article The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma Cinzia Di Pietro, Marco Ragusa, Davide Barbagallo, Laura R Duro, Maria R Guglielmino, Alessandra Majorana, Rosario Angelica, Marina Scalia, Luisa Statello, Loredana Salito, Luisa Tomasello, Salvo Pernagallo, Salvo Valenti, Vito D'Agostino, Patrizio Triberio, Igor Tandurella, Giuseppe A Palumbo, Piera La Cava, Viviana Cafiso, Taschia Bertuccio, Maria Santagati, Giovanni Li Destri, Salvatore Lanzafame, Francesco Di Raimondo, Stefania Stefani, Bud Mishra, Michele Purrello BMC Medical Genomics 2009, 2:20 (30 April 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central