BMC Medical Genomics | Most Viewed

Submit a manuscript Register Contact us Follow us on

Explore BMC Medical Genomics

Articles

Display/download options Articles per page: 25 | 50 | 100

Display options

Editor's summary Citation

Download options

Send
To

	All
	1. 1235 Accesses	Research article A target based approach identifies genomic predictors of breast cancer patient response to chemotherapy Robin M Hallett, Gregory Pond, John A Hassell BMC Medical Genomics 2012, 5:16 (11 May 2012) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Two new gene expression signatures can predict how breast cancer tumors will respond to two of the common kinds of chemotherapy, highlighting the potential of target-based gene expression indices to predict patient response to drug therapy.
	2. 682 Accesses	Review Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases Douglas B Kell BMC Medical Genomics 2009, 2:2 (8 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Douglas Kell reviews the role of iron-catalysed free radicals in disease, which underpin the behavior of many physiological and pathological processes, and considers the need for better understanding using an integrative, systems-level approach.
	3. 551 Accesses	Research article Identification of genes with a correlation between copy number and expression in gastric cancer Lei Cheng, Ping Wang, Sheng Yang, Yanqing Yang, Qing Zhang, Wen Zhang, Huasheng Xiao, Hengjun Gao, Qinghua Zhang BMC Medical Genomics 2012, 5:14 (4 May 2012) Abstract \| Provisional PDF \| PubMed
	4. 544 Accesses	Research article DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease? Nahid Turan, Mohamed F Ghalwash, Sunita Katari, Christos Coutifaris, Zoran Obradovic, Carmen Sapienza BMC Medical Genomics 2012, 5:10 (12 April 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Profiling of inter-individual DNA methylation differences in neonates has identified 23 genes that account for 70-87% of variance in birth weight, whilst traditional gene expression profiling identified a far smaller proportion.
	5. 370 Accesses	Research article Fibroblasts from phenotypically normal palmar fascia exhibit molecular profiles highly similar to fibroblasts from active disease in Dupuytren's Contracture Latha Satish, William A LaFramboise, Sandra Johnson, Linda Vi, Anna Njarlangattil, Christina Raykha, Michael J Krill-Burger, Phillip H Gallo, David B O'Gorman, Bing SIANG Gan, Mark E Baratz, Garth D Ehrlich, Sandeep H Kathju BMC Medical Genomics 2012, 5:15 (4 May 2012) Abstract \| Provisional PDF \| PubMed
	6. 359 Accesses	Research article Interaction among apoptosis-associated sequence variants and joint effects on aggressive prostate cancer Nicole A Lavender, Erica N Rogers, Susan Yeyeodu, James Rudd, Ting Hu, Jie Zhang, Guy N Brock, Kevin S Kimbro, Jason H Moore, David W Hein, La Creis R Kidd BMC Medical Genomics 2012, 5:11 (30 April 2012) Abstract \| Full text \| PDF \| PubMed
	7. 355 Accesses	Research article Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform Sarah De Keulenaer, Jan Hellemans, Steve Lefever, Jean-Pierre Renard, Joachim De Schrijver, Hendrik Van de Voorde, Mohammad Amin Tabatabaiefar, Filip Van Nieuwerburgh, Daisy Flamez, Filip Pattyn, Bieke Scharlaken, Dieter Deforce, Sofie Bekaert, Wim Van Criekinge, Jo Vandesompele, Guy Van Camp, Paul Coucke BMC Medical Genomics 2012, 5:17 (18 May 2012) Abstract \| Provisional PDF \| PubMed
	8. 320 Accesses	Research article Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children Adam D Irwin, Fiona Marriage, Limangeni A Mankhambo, IPD Study Group, Graham Jeffers, Ruwanthi Kolamunnage-Dona, Malcolm Guiver, Brigitte Denis, Elizabeth M Molyneux, Malcolm E Molyneux, Philip J Day, Enitan D Carrol BMC Medical Genomics 2012, 5:13 (4 May 2012) Abstract \| Provisional PDF \| PubMed
	9. 294 Accesses	Research article Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects Jarkko Soronen, Pirkka-Pekka P Laurila, Jussi Naukkarinen, Ida Surakka, Samuli Ripatti, Matti Jauhiainen, Vesa M Olkkonen, Hannele Yki-Jarvinen BMC Medical Genomics 2012, 5:9 (3 April 2012) Abstract \| Provisional PDF \| PubMed
	10. 284 Accesses	Research article Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus Christopher G Bell, Andrew E Teschendorff, Vardhman K Rakyan, Alexander P Maxwell, Stephan Beck, David A Savage BMC Medical Genomics 2010, 3:33 (5 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	11. 285 Accesses	Research article Batch effect correction for genome-wide methylation data with Illumina Infinium platform Zhifu Sun, High Chai, Yanhong Wu, Wendy M White, Krishna V Donkena, Christopher J Klein, Vesna D Garovic, Terry M Therneau, Jean-Pierre A Kocher BMC Medical Genomics 2011, 4:84 (16 December 2011) Abstract \| Full text \| PDF \| PubMed
	12. 276 Accesses	Research article Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity Martin Kerick, Melanie Isau, Bernd Timmermann, Holger Sültmann, Ralf Herwig, Sylvia Krobitsch, Georg Schaefer, Irmgard Verdorfer, Georg Bartsch, Helmut Klocker, Hans Lehrach, Michal R Schweiger BMC Medical Genomics 2011, 4:68 (29 September 2011) Abstract \| Full text \| PDF \| PubMed
	13. 254 Accesses	Research article Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities Reinhold J Medina, Christina L O'Neill, Mark Sweeney, Jasenka Guduric-Fuchs, Tom A Gardiner, David A Simpson, Alan W Stitt BMC Medical Genomics 2010, 3:18 (13 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Medicine \| F1000 Biology
	14. 242 Accesses	Correspondence The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies Catherine A McCarty, Rex L Chisholm, Christopher G Chute, Iftikhar J Kullo, Gail P Jarvik, Eric B Larson, Rongling Li, Daniel R Masys, Marylyn D Ritchie, Dan M Roden, Jeffery P Struewing, Wendy A Wolf, the eMERGE Team BMC Medical Genomics 2011, 4:13 (26 January 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	15. 235 Accesses	Research article High-throughput detection of aberrant imprint methylation in the ovarian cancer by the bisulphite PCR-Luminex method Hitoshi Hiura, Hiroaki Okae, Hisato Kobayash, Naoko Miyauchi, Fumi Sato, Akiko Sato, Fumihiko Suzuki, Satoru Nagase, Junichi Sugawara, Kunihiko Nakai, Nobuo Yaegashi, Takahiro Arima BMC Medical Genomics 2012, 5:8 (26 March 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Aberrant patterns of methylation are found in samples from patients with ovarian cancer using the new bisulphate PCR-Luminex (BPL) method, highlighting H19 and PEG1 as potential biomarkers for the disease.
	16. 229 Accesses	Research article An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma Zhaohui Luo, Liyang Zhang, Zheng Li, Xiayu Li, Gang Li, Haibo Yu, Chen Jiang, Yafei Dai, Xiaofang Guo, Juanjuan Xiang, Guiyuan Li BMC Medical Genomics 2012, 5:3 (19 January 2012) Abstract \| Full text \| PDF \| PubMed
	17. 228 Accesses	Research article A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors Andrey Loboda, Michael Nebozhyn, Rich Klinghoffer, Jason Frazier, Michael Chastain, William Arthur, Brian Roberts, Theresa Zhang, Melissa Chenard, Brian Haines, Jannik Andersen, Kumiko Nagashima, Cloud Paweletz, Bethany Lynch, Igor Feldman, Hongyue Dai, Pearl Huang, James Watters BMC Medical Genomics 2010, 3:26 (30 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	18. 226 Accesses	Research article Evaluation of the imputation performance of the program IMPUTE in an admixed sample from Mexico City using several model designs S Krithika, Adán Valladares-Salgado, Jesus Peralta, Jorge Escobedo-de La Peña, Jesus Kumate-Rodríguez, Miguel Cruz, Esteban J Parra BMC Medical Genomics 2012, 5:12 (1 May 2012) Abstract \| Provisional PDF \| PubMed
	19. 225 Accesses	Research article Modeling microRNA-mRNA Interactions Using PLS Regression in Human Colon Cancer Xiaohong Li, Ryan Gill, Nigel GF Cooper, Jae Yoo, Susmita Datta BMC Medical Genomics 2011, 4:44 (19 May 2011) Abstract \| Full text \| PDF \| PubMed
	20. 206 Accesses	Research article Impact of RNA degradation on gene expression profiling Lennart Opitz, Gabriela Salinas-Riester, Marian Grade, Klaus Jung, Peter Jo, Georg Emons, B Michael Ghadimi, Tim Beißbarth, Jochen Gaedcke BMC Medical Genomics 2010, 3:36 (9 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	21. 195 Accesses	Research article MicroRNA profiling of diverse endothelial cell types Matthew N McCall, Oliver A Kent, Jianshi Yu, Karen Fox-Talbot, Ari L Zaiman, Marc K Halushka BMC Medical Genomics 2011, 4:78 (2 November 2011) Abstract \| Full text \| PDF \| PubMed
	22. 196 Accesses	Research article Exploring the oral microbiota of children at various developmental stages of their dentition in the relation to their oral health Wim Crielaard, Egija Zaura, Annemarie A Schuller, Susan M Huse, Roy C Montijn, Bart JF Keijser BMC Medical Genomics 2011, 4:22 (4 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23. 192 Accesses	Research article Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping Jean E Abraham, Mel J Maranian, Inmaculada Spiteri, Roslin Russell, Susan Ingle, Craig Luccarini, Helena M Earl, Paul DP Pharoah, Alison M Dunning, Carlos Caldas BMC Medical Genomics 2012, 5:19 (30 May 2012) Abstract \| Provisional PDF
	24. 191 Accesses	Research article Integrative analysis of next generation sequencing for small non-coding RNAs and transcriptional regulation in Myelodysplastic Syndromes Dominik Beck, Steve Ayers, Jianguo Wen, Miriam B Brandl, Tuan D Pham, Paul Webb, Chung-Che Chang, Xiaobo Zhou BMC Medical Genomics 2011, 4:19 (23 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	25. 180 Accesses	Research article EMT is the dominant program in human colon cancer Andre Loboda, Michael V Nebozhyn, James W Watters, Carolyne A Buser, Peter Shaw, Pearl S Huang, Laura Van't Veer, Rob AEM Tollenaar, David B Jackson, Deepak Agrawal, Hongyue Dai, Timothy J Yeatman BMC Medical Genomics 2011, 4:9 (20 January 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The intrinsic first principal component (PC1) signature, tightly correlated with epithelial-mesenchymal transition (EMT), is highly prognostic for colon cancer recurrence and may also aid in sub classifying multiple types of cancer and their novel therapeutics.