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		Research article Detailed transcriptome atlas of the pancreatic beta cell Burak Kutlu, David Burdick, David Baxter, Joanne Rasschaert, Daisy Flamez, Decio L Eizirik, Nils Welsh, Nathan Goodman, Leroy Hood BMC Medical Genomics 2009, 2:3 (15 January 2009) Abstract \| Full text \| PDF \| PubMed
		Review Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases Douglas B Kell BMC Medical Genomics 2009, 2:2 (8 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Douglas Kell reviews the role of iron-catalysed free radicals in disease, which underpin the behavior of many physiological and pathological processes, and considers the need for better understanding using an integrative, systems-level approach.
		Research article Complex nature of SNP genotype effects on gene expression in primary human leucocytes Graham A Heap, Gosia Trynka, Ritsert C Jansen, Marcel Bruinenberg, Morris A Swertz, Lotte C Dinesen, Karen A Hunt, Cisca Wijmenga, David A vanHeel, Lude Franke BMC Medical Genomics 2009, 2:1 (7 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Genomic selection of reference genes for real-time PCR in human myocardium Anna P Pilbrow, Leigh J Ellmers, Michael A Black, Christine S Moravec, Wendy E Sweet, Richard W Troughton, A Mark Richards, Chris M Frampton, Vicky A Cameron BMC Medical Genomics 2008, 1:64 (29 December 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Global gene expression analyses of bystander and alpha particle irradiated normal human lung fibroblasts: Synchronous and differential responses Shanaz A Ghandhi, Benjamin Yaghoubian, Sally A Amundson BMC Medical Genomics 2008, 1:63 (24 December 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Biological processes, properties and molecular wiring diagrams of candidate low-penetrance breast cancer susceptibility genes Núria Bonifaci, Antoni Berenguer, Javier Díez, Oscar Reina, Ignacio Medina, Joaquín Dopazo, Víctor Moreno, Miguel Pujana BMC Medical Genomics 2008, 1:62 (18 December 2008) Abstract \| Full text \| PDF \| PubMed
		Research article An expression meta-analysis of predicted microRNA targets identifies a diagnostic signature for lung cancer Yu Liang BMC Medical Genomics 2008, 1:61 (16 December 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism Sandy Mosig, Knut Rennert, Petra Büttner, Siegfried Krause, Dieter Lütjohann, Muhidien Soufi, Regine Heller, Harald Funke BMC Medical Genomics 2008, 1:60 (28 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Carboplatin-induced gene expression changes in vitro are prognostic of survival in epithelial ovarian cancer Panagiotis A Konstantinopoulos, Elena Fountzilas, Kamana Pillay, Luiz F Zerbini, Towia A Libermann, Stephen A Cannistra, Dimitrios Spentzos BMC Medical Genomics 2008, 1:59 (28 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Database New Jersey Center for Tourette Syndrome Sharing Repository: methods and sample description Gary A Heiman, Robert A King, Jay A Tischfield BMC Medical Genomics 2008, 1:58 (26 November 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Discovery of DNA methylation markers in cervical cancer using relaxation ranking Maté Ongenaert, G Bea A Wisman, Haukeline H Volders, Alice J Koning, Ate Zee, Wim van Criekinge, Ed Schuuring BMC Medical Genomics 2008, 1:57 (24 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Searching for molecular markers in head and neck squamous cell carcinomas (HNSCC) by statistical and bioinformatic analysis of larynx-derived SAGE libraries Nelson JF Silveira, Leonardo Varuzza, Ariane Machado-Lima, Marcelo S Lauretto, Daniel G Pinheiro, Rodrigo V Rodrigues, Patrícia Severino, Francisco G Nobrega, Head and Neck Genome Project GENCAPO, Wilson A Silva, Carlos A de B Pereira, Eloiza H Tajara BMC Medical Genomics 2008, 1:56 (11 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients Salla Ruosaari, Tuija Hienonen-Kempas, Anne Puustinen, Virinder K Sarhadi, Jaakko Hollmén, Sakari Knuutila, Juha Saharinen, Harriet Wikman, Sisko Anttila BMC Medical Genomics 2008, 1:55 (11 November 2008) Abstract \| Full text \| PDF \| PubMed
		Research article The distinctive gastric fluid proteome in gastric cancer reveals a multi-biomarker diagnostic profile Oi Kon, Tai-Tung Yip, Meng Ho, Weng Chan, Wai Wong, Soo Tan, Wai Ng, Siok Kam, Alvin KH Eng, Patrick Ho, Rosa Viner, Hock Ong, M Priyanthi Kumarasinghe BMC Medical Genomics 2008, 1:54 (25 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article A global transcriptional view of apoptosis in human T-cell activation Min Wang, Dirk Windgassen, Eleftherios T Papoutsakis BMC Medical Genomics 2008, 1:53 (23 October 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age Yohan Lee, Adrienne C Scheck, Timothy F Cloughesy, Albert Lai, Jun Dong, Haumith K Farooqi, Linda M Liau, Steve Horvath, Paul S Mischel, Stanley F Nelson BMC Medical Genomics 2008, 1:52 (21 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Younger patients with the most serious grade of brain tumor, glioblastoma multiforme, may survive longer because they are more likely to present with the gene signature of the proneural subtype relative to more common and aggressive forms.
		Technical advance Expression-based Pathway Signature Analysis (EPSA): Mining publicly available microarray data for insight into human disease Jessica D Tenenbaum, Michael G Walker, Paul J Utz, Atul J Butte BMC Medical Genomics 2008, 1:51 (20 October 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Multiplex ligation-dependent probe amplification for genetic screening in autism spectrum disorders: Efficient identification of known microduplications and identification of a novel microduplication in ASMT Guiqing Cai, Lisa Edelmann, Juliet E Goldsmith, Ninette Cohen, Alisa Nakamine, Jennifer G Reichert, Ellen J Hoffman, Danielle M Zurawiecki, Jeremy M Silverman, Eric Hollander, Latha Soorya, Evdokia Anagnostou, Catalina Betancur, Joseph D Buxbaum BMC Medical Genomics 2008, 1:50 (16 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Multiplex ligation-dependent probe amplification (MPLA) identifies known and novel chromosomal abnormalities in children with autism spectrum disorders and associated cognitive impairment, suggesting that MPLA has the potential to be an effective screening method for these conditions.
		Research article The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines Christian RA Regenbrecht, Marc Jung, Hans Lehrach, James Adjaye BMC Medical Genomics 2008, 1:49 (10 October 2008) Abstract \| Full text \| PDF \| PubMed
		Research article The Comparative Toxicogenomics Database facilitates identification and understanding of chemical-gene-disease associations: arsenic as a case study Allan P Davis, Cynthia G Murphy, Michael C Rosenstein, Thomas C Wiegers, Carolyn J Mattingly BMC Medical Genomics 2008, 1:48 (9 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage George S Watts, Bernard W Futscher, Nicholas Holtan, Koen DeGeest, Frederick E Domann, Stephen L Rose BMC Medical Genomics 2008, 1:47 (30 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A reliable predictor for ovarian cancer progression based on microarray analysis of methylation changes reveals that Alu and satellite repeats are hypomethylated whereas promoter CpG islands are hypermethylated with more advanced disease.
		Research article A systems biology approach to construct the gene regulatory network of systemic inflammation via microarray and databases mining Bor-Sen Chen, Shih-Kuang Yang, Chung-Yu Lan, Yung-Jen Chuang BMC Medical Genomics 2008, 1:46 (30 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Gene expression in BMPR2 mutation carriers with and without evidence of Pulmonary Arterial Hypertension suggests pathways relevant to disease penetrance James West, Joy Cogan, Mark Geraci, Linda Robinson, John Newman, John A Phillips, Kirk Lane, Barbara Meyrick, Jim Loyd BMC Medical Genomics 2008, 1:45 (29 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article A genome-wide association study for late-onset Alzheimer's disease using DNA pooling Richard Abraham, Valentina Moskvina, Rebecca Sims, Paul Hollingworth, Angharad Morgan, Lyudmila Georgieva, Kimberley Dowzell, Sven Cichon, Axel M Hillmer, Michael C O'Donovan, Julie Williams, Michael J Owen, George Kirov BMC Medical Genomics 2008, 1:44 (29 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Regulatory subunits of PKA define an axis of cellular proliferation/differentiation in ovarian cancer cells Chris Cheadle, Maria Nesterova, Tonya Watkins, Kathleen C Barnes, John C Hall, Antony Rosen, Kevin G Becker, Yoon S Cho-Chung BMC Medical Genomics 2008, 1:43 (26 September 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Overexpression of the regulatory subunit of cAMP-dependent protein kinase (PKA) in ovarian cancer cells causes hyperproliferation for the RI isoform and differentiation for RII, suggesting that PKA may be pivotal in disease progression.

	All
		Research article Detailed transcriptome atlas of the pancreatic beta cell Burak Kutlu, David Burdick, David Baxter, Joanne Rasschaert, Daisy Flamez, Decio L Eizirik, Nils Welsh, Nathan Goodman, Leroy Hood BMC Medical Genomics 2009, 2:3 (15 January 2009) Abstract \| Full text \| PDF \| PubMed
		Review Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases Douglas B Kell BMC Medical Genomics 2009, 2:2 (8 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Douglas Kell reviews the role of iron-catalysed free radicals in disease, which underpin the behavior of many physiological and pathological processes, and considers the need for better understanding using an integrative, systems-level approach.
		Research article Complex nature of SNP genotype effects on gene expression in primary human leucocytes Graham A Heap, Gosia Trynka, Ritsert C Jansen, Marcel Bruinenberg, Morris A Swertz, Lotte C Dinesen, Karen A Hunt, Cisca Wijmenga, David A vanHeel, Lude Franke BMC Medical Genomics 2009, 2:1 (7 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Genomic selection of reference genes for real-time PCR in human myocardium Anna P Pilbrow, Leigh J Ellmers, Michael A Black, Christine S Moravec, Wendy E Sweet, Richard W Troughton, A Mark Richards, Chris M Frampton, Vicky A Cameron BMC Medical Genomics 2008, 1:64 (29 December 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Global gene expression analyses of bystander and alpha particle irradiated normal human lung fibroblasts: Synchronous and differential responses Shanaz A Ghandhi, Benjamin Yaghoubian, Sally A Amundson BMC Medical Genomics 2008, 1:63 (24 December 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Biological processes, properties and molecular wiring diagrams of candidate low-penetrance breast cancer susceptibility genes Núria Bonifaci, Antoni Berenguer, Javier Díez, Oscar Reina, Ignacio Medina, Joaquín Dopazo, Víctor Moreno, Miguel Pujana BMC Medical Genomics 2008, 1:62 (18 December 2008) Abstract \| Full text \| PDF \| PubMed
		Research article An expression meta-analysis of predicted microRNA targets identifies a diagnostic signature for lung cancer Yu Liang BMC Medical Genomics 2008, 1:61 (16 December 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism Sandy Mosig, Knut Rennert, Petra Büttner, Siegfried Krause, Dieter Lütjohann, Muhidien Soufi, Regine Heller, Harald Funke BMC Medical Genomics 2008, 1:60 (28 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Carboplatin-induced gene expression changes in vitro are prognostic of survival in epithelial ovarian cancer Panagiotis A Konstantinopoulos, Elena Fountzilas, Kamana Pillay, Luiz F Zerbini, Towia A Libermann, Stephen A Cannistra, Dimitrios Spentzos BMC Medical Genomics 2008, 1:59 (28 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Database New Jersey Center for Tourette Syndrome Sharing Repository: methods and sample description Gary A Heiman, Robert A King, Jay A Tischfield BMC Medical Genomics 2008, 1:58 (26 November 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Discovery of DNA methylation markers in cervical cancer using relaxation ranking Maté Ongenaert, G Bea A Wisman, Haukeline H Volders, Alice J Koning, Ate Zee, Wim van Criekinge, Ed Schuuring BMC Medical Genomics 2008, 1:57 (24 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Searching for molecular markers in head and neck squamous cell carcinomas (HNSCC) by statistical and bioinformatic analysis of larynx-derived SAGE libraries Nelson JF Silveira, Leonardo Varuzza, Ariane Machado-Lima, Marcelo S Lauretto, Daniel G Pinheiro, Rodrigo V Rodrigues, Patrícia Severino, Francisco G Nobrega, Head and Neck Genome Project GENCAPO, Wilson A Silva, Carlos A de B Pereira, Eloiza H Tajara BMC Medical Genomics 2008, 1:56 (11 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients Salla Ruosaari, Tuija Hienonen-Kempas, Anne Puustinen, Virinder K Sarhadi, Jaakko Hollmén, Sakari Knuutila, Juha Saharinen, Harriet Wikman, Sisko Anttila BMC Medical Genomics 2008, 1:55 (11 November 2008) Abstract \| Full text \| PDF \| PubMed
		Research article The distinctive gastric fluid proteome in gastric cancer reveals a multi-biomarker diagnostic profile Oi Kon, Tai-Tung Yip, Meng Ho, Weng Chan, Wai Wong, Soo Tan, Wai Ng, Siok Kam, Alvin KH Eng, Patrick Ho, Rosa Viner, Hock Ong, M Priyanthi Kumarasinghe BMC Medical Genomics 2008, 1:54 (25 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article A global transcriptional view of apoptosis in human T-cell activation Min Wang, Dirk Windgassen, Eleftherios T Papoutsakis BMC Medical Genomics 2008, 1:53 (23 October 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age Yohan Lee, Adrienne C Scheck, Timothy F Cloughesy, Albert Lai, Jun Dong, Haumith K Farooqi, Linda M Liau, Steve Horvath, Paul S Mischel, Stanley F Nelson BMC Medical Genomics 2008, 1:52 (21 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Younger patients with the most serious grade of brain tumor, glioblastoma multiforme, may survive longer because they are more likely to present with the gene signature of the proneural subtype relative to more common and aggressive forms.
		Technical advance Expression-based Pathway Signature Analysis (EPSA): Mining publicly available microarray data for insight into human disease Jessica D Tenenbaum, Michael G Walker, Paul J Utz, Atul J Butte BMC Medical Genomics 2008, 1:51 (20 October 2008) Abstract \| Full text \| PDF \| PubMed
		Research article Multiplex ligation-dependent probe amplification for genetic screening in autism spectrum disorders: Efficient identification of known microduplications and identification of a novel microduplication in ASMT Guiqing Cai, Lisa Edelmann, Juliet E Goldsmith, Ninette Cohen, Alisa Nakamine, Jennifer G Reichert, Ellen J Hoffman, Danielle M Zurawiecki, Jeremy M Silverman, Eric Hollander, Latha Soorya, Evdokia Anagnostou, Catalina Betancur, Joseph D Buxbaum BMC Medical Genomics 2008, 1:50 (16 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Multiplex ligation-dependent probe amplification (MPLA) identifies known and novel chromosomal abnormalities in children with autism spectrum disorders and associated cognitive impairment, suggesting that MPLA has the potential to be an effective screening method for these conditions.
		Research article The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines Christian RA Regenbrecht, Marc Jung, Hans Lehrach, James Adjaye BMC Medical Genomics 2008, 1:49 (10 October 2008) Abstract \| Full text \| PDF \| PubMed
		Research article The Comparative Toxicogenomics Database facilitates identification and understanding of chemical-gene-disease associations: arsenic as a case study Allan P Davis, Cynthia G Murphy, Michael C Rosenstein, Thomas C Wiegers, Carolyn J Mattingly BMC Medical Genomics 2008, 1:48 (9 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage George S Watts, Bernard W Futscher, Nicholas Holtan, Koen DeGeest, Frederick E Domann, Stephen L Rose BMC Medical Genomics 2008, 1:47 (30 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A reliable predictor for ovarian cancer progression based on microarray analysis of methylation changes reveals that Alu and satellite repeats are hypomethylated whereas promoter CpG islands are hypermethylated with more advanced disease.
		Research article A systems biology approach to construct the gene regulatory network of systemic inflammation via microarray and databases mining Bor-Sen Chen, Shih-Kuang Yang, Chung-Yu Lan, Yung-Jen Chuang BMC Medical Genomics 2008, 1:46 (30 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Gene expression in BMPR2 mutation carriers with and without evidence of Pulmonary Arterial Hypertension suggests pathways relevant to disease penetrance James West, Joy Cogan, Mark Geraci, Linda Robinson, John Newman, John A Phillips, Kirk Lane, Barbara Meyrick, Jim Loyd BMC Medical Genomics 2008, 1:45 (29 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article A genome-wide association study for late-onset Alzheimer's disease using DNA pooling Richard Abraham, Valentina Moskvina, Rebecca Sims, Paul Hollingworth, Angharad Morgan, Lyudmila Georgieva, Kimberley Dowzell, Sven Cichon, Axel M Hillmer, Michael C O'Donovan, Julie Williams, Michael J Owen, George Kirov BMC Medical Genomics 2008, 1:44 (29 September 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Regulatory subunits of PKA define an axis of cellular proliferation/differentiation in ovarian cancer cells Chris Cheadle, Maria Nesterova, Tonya Watkins, Kathleen C Barnes, John C Hall, Antony Rosen, Kevin G Becker, Yoon S Cho-Chung BMC Medical Genomics 2008, 1:43 (26 September 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Overexpression of the regulatory subunit of cAMP-dependent protein kinase (PKA) in ovarian cancer cells causes hyperproliferation for the RI isoform and differentiation for RII, suggesting that PKA may be pivotal in disease progression.