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Research article   Open Access

Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells

Hongjuan Zhao, Vincent Flamand, Donna M Peehl BMC Medical Genomics 2009, 2:55 (20 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes

Blanca M Herrera, Helen E Lockstone, Jennifer M Taylor, Quin F Wills, Pamela J Kaisaki, Amy Barrett, Carme Camps, Christina Fernandez, Jiannis Ragoussis, Dominique Gauguier, Mark I McCarthy, Cecilia M Lindgren BMC Medical Genomics 2009, 2:54 (18 August 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Combining global microRNA and mRNA expression data indicates MiR-125a is over-expressed in the liver of hyperglycaemic rats and is a putative modulator of glucose and lipid metabolism in a rat model of type 2 diabetes.

Research article   Open Access Highly Accessed

Verification of genes differentially expressed in neuroblastoma tumours: a study of potential tumour suppressor genes

Kaisa Thorell, Annika Bergman, Helena Carén, Staffan Nilsson, Per Kogner, Tommy Martinsson, Frida Abel BMC Medical Genomics 2009, 2:53 (17 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

A gene expression profile for detection of sufficient tumour cells in breast tumour tissue: microarray diagnosis eligibility

Paul Roepman, Arenda Schuurman, Leonie JMJ Delahaye, Anke T Witteveen, Arno N Floore, Annuska M Glas BMC Medical Genomics 2009, 2:52 (12 August 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Hepatic inflammation mediated by hepatitis C virus core protein is ameliorated by blocking complement activation

Ming-Ling Chang, Chau-Ting Yeh, Deng-Yn Lin, Yu-Pin Ho, Chen-Ming Hsu, D Montgomery Bissell BMC Medical Genomics 2009, 2:51 (8 August 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Integrated microarray and multiplex cytokine analyses of Kaposi's Sarcoma Associated Herpesvirus viral FLICE Inhibitory Protein K13 affected genes and cytokines in human blood vascular endothelial cells

Vasu Punj, Hittu Matta, Sandra Schamus, Preet M Chaudhary BMC Medical Genomics 2009, 2:50 (6 August 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood

Boryana S Stamova, Michelle Apperson, Wynn L Walker, Yingfang Tian, Huichun Xu, Peter Adamczy, Xinhua Zhan, Da-Zhi Liu, Bradley P Ander, Isaac H Liao, Jeffrey P Gregg, Renee J Turner, Glen Jickling, Lisa Lit, Frank R Sharp BMC Medical Genomics 2009, 2:49 (5 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Candidate pathways and genes for prostate cancer: a meta-analysis of gene expression data

Ivan P Gorlov, Jinyoung Byun, Olga Y Gorlova, Ana M Aparicio, Eleni Efstathiou, Christopher J Logothetis BMC Medical Genomics 2009, 2:48 (4 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Host sequence motifs shared by HIV predict response to antiretroviral therapy

William Dampier, Perry Evans, Lyle Ungar, Aydin Tozeren BMC Medical Genomics 2009, 2:47 (23 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Prediction of acute multiple sclerosis relapses by transcription levels of peripheral blood cells

Michael Gurevich, Tamir Tuller, Udi Rubinstein, Rotem Or-Bach, Anat Achiron BMC Medical Genomics 2009, 2:46 (22 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

An assessment of the portability of ancestry informative markers between human populations

Sean Myles, Mark Stoneking, Nic Timpson BMC Medical Genomics 2009, 2:45 (20 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Novel transcriptional profile in wrist muscles from cerebral palsy patients

Lucas R Smith, Eva Pontén, Yvette Hedström, Samuel R Ward, Henry G Chambers, Shankar Subramaniam, Richard L Lieber BMC Medical Genomics 2009, 2:44 (14 July 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Finding exclusively deleted or amplified genomic areas in lung adenocarcinomas using a novel chromosomal pattern analysis

Philippe Broët, Patrick Tan, Marco Alifano, Sophie Camilleri-Broët, Sylvia Richardson BMC Medical Genomics 2009, 2:43 (14 July 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Genomic profiling distinguishes familial multiple and sporadic multiple meningiomas

Yiping Shen, Fabio Nunes, Anat Stemmer-Rachamimov, Marianne James, Gayatry Mohapatra, Scott Plotkin, Rebecca A Betensky, David A Engler, Jennifer Roy, Vijaya Ramesh, James F Gusella BMC Medical Genomics 2009, 2:42 (9 July 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus

Yaomin Hu, Pamela J Kaisaki, Karène Argoud, Steven P Wilder, Karin J Wallace, Peng Y Woon, Christine Blancher, Lise Tarnow, Per-Henrik Groop, Samy Hadjadj, Michel Marre, Hans-Henrik Parving, Martin Farrall, Roger D Cox, Mark Lathrop, Nathalie Vionnet, Marie-Thérèse Bihoreau, Dominique Gauguier BMC Medical Genomics 2009, 2:41 (9 July 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

The Gene expression Grade Index: a potential predictor of relapse for endocrine-treated breast cancer patients in the BIG 1–98 trial

Christine Desmedt, Anita Giobbie-Hurder, Patrick Neven, Robert Paridaens, Marie-Rose Christiaens, Ann Smeets, Françoise Lallemand, Benjamin Haibe-Kains, Giuseppe Viale, Richard D Gelber, Martine Piccart, Christos Sotiriou BMC Medical Genomics 2009, 2:40 (2 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

NMD inhibition fails to identify tumour suppressor genes in microsatellite stable gastric cancer cell lines

Tineke E Buffart, Marianne Tijssen, Jamila El-Bchiri, Alex Duval, Mark Wiel, Bauke Ylstra, Gerrit A Meijer, Beatriz Carvalho BMC Medical Genomics 2009, 2:39 (29 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

Research article   Open Access Highly Accessed

A gene signature for post-infectious chronic fatigue syndrome

John W Gow, Suzanne Hagan, Pawel Herzyk, Celia Cannon, Peter O Behan, Abhijit Chaudhuri BMC Medical Genomics 2009, 2:38 (25 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer

Sherene Loi, Christos Sotiriou, Benjamin Haibe-Kains, Francoise Lallemand, Nelly M Conus, Martine J Piccart, Terence P Speed, Grant A McArthur BMC Medical Genomics 2009, 2:37 (24 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Activation of growth factor (GF) signalling contributes to the tamoxifen-insensitive estrogen receptor-positive breast cancer phenotype independent of human epidermal growth factor receptor (HER2) gene expression, suggesting an alternative therapeutic target for this aggressive disease.

Research article   Open Access

MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures

Andrea Zangrando, Marta Dell'Orto, Geertruy te Kronnie, Giuseppe Basso BMC Medical Genomics 2009, 2:36 (23 June 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Identification and analysis of miRNAs in human breast cancer and teratoma samples using deep sequencing

Sanne Nygaard, Anders Jacobsen, Morten Lindow, Jens Eriksen, Eva Balslev, Henrik Flyger, Niels Tolstrup, Søren Møller, Anders Krogh, Thomas Litman BMC Medical Genomics 2009, 2:35 (9 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Analysis of breast cancer and adjacent tissue using deep-sequencing technology and a novel computational pipeline identifies 5 new microRNAs, and indicates that sequence end variability may be used as a discriminatory feature to aid future microRNA discovery.

Research article   Open Access Highly Accessed

Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer

Meng Li, Curt Balch, John S Montgomery, Mikyoung Jeong, Jae Chung, Pearlly Yan, Tim HM Huang, Sun Kim, Kenneth P Nephew BMC Medical Genomics 2009, 2:34 (8 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

A longitudinal study of gene expression in healthy individuals

Chris Karlovich, Guillemette Duchateau-Nguyen, Andrea Johnson, Patricia McLoughlin, Mercidita Navarro, Carole Fleurbaey, Lori Steiner, Michel Tessier, Tracy Nguyen, Monika Wilhelm-Seiler, John P Caulfield BMC Medical Genomics 2009, 2:33 (7 June 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Genomic profiling identifies common HPV-associated chromosomal alterations in squamous cell carcinomas of cervix and head and neck

Saskia M Wilting, Serge J Smeets, Peter JF Snijders, Wessel N van Wieringen, Mark A van de Wiel, Gerrit A Meijer, Bauke Ylstra, C René Leemans, Chris JLM Meijer, Ruud H Brakenhoff, Boudewijn JM Braakhuis, Renske DM Steenbergen BMC Medical Genomics 2009, 2:32 (1 June 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Identification of gene co-regulatory modules and associated cis-elements involved in degenerative heart disease

Charles G Danko, Arkady M Pertsov BMC Medical Genomics 2009, 2:31 (28 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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