Section Editors
- Debashis Ghosh, Pennsylvania State University
- Struan Grant, Children's Hospital of Philadelphia
- Patrice Morin, National Institute on Aging, NIH
- Patrick Tan, Graduate Medical School Singapore
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- Tim Sands , BioMed Central
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Articles
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BMC Medical Genomics 2012, 5:16Predicting chemotherapy response
Two new gene expression signatures can predict how breast cancer tumors will respond to two of the common kinds of chemotherapy, highlighting the potential of target-based gene expression indices to predict patient response to drug therapy.
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BMC Medical Genomics 2012, 5:10Identification of birth weight-related genes
Profiling of inter-individual DNA methylation differences in neonates has identified 23 genes that account for 70-87% of variance in birth weight, whilst traditional gene expression profiling identified a far smaller proportion.
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BMC Medical Genomics 2012, 5:8BPL method detects ovarian cancer biomarkers
Aberrant patterns of methylation are found in samples from patients with ovarian cancer using the new bisulphate PCR-Luminex (BPL) method, highlighting H19 and PEG1 as potential biomarkers for the disease.
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BMC Medical Genomics 2012, 5:2Predicting early atherosclerosis
An new set of 56 gene expression biomarkers could be used to predict early atherosclerosis from leukocytes before the symptoms of heart disease have developed, and this test can be further refined to identify very high risk patients.
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BMC Medical Genomics is an open access, peer-reviewed journal that considers articles on all aspects of functional genomics, genome structure, genome-scale population genetics, epigenomics, proteomics, systems analysis, and pharmacogenomics in relation to human health and disease.
It is journal policy to publish work deemed by peer reviewers to be a coherent and sound addition to scientific knowledge and to put less emphasis on interest levels, provided that the research constitutes a useful contribution to the field.
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Semel Institute for Neuroscience & Human Behavior,
UCLA David Geffen School of Medicine, USA
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