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Editor-in-Chief Melissa Norton, MD
Medical Editor Jigisha Patel, MRCP PhD
In-house Editor Scott Edmunds
Welcome to BMC Medical Genomics published by BioMed Central
BMC Medical Genomics is an open access journal publishing original peer-reviewed research articles in all aspects of functional genomics, genome structure, genome-scale population genetics, epigenomics, proteomics, systems analysis, and pharmacogenomics in relation to human health and disease.
BMC Medical Genomics (ISSN 1755-8794) is indexed/tracked/covered by PubMed, BIOSIS, CAS and Google Scholar.
BMC Medical Genomics 2008, 1 :6
Midkine, a heparin-binding growth factor expressed in human cancers, is induced in prostate cancer cells by cytokines and other growth factors, particularly TNFalpha, correlating with the high levels of this cytokine observed in advanced prostate tumors
BMC Medical Genomics 2008, 1 :3
Detailed mapping of chromosomal aberrations in urothelial carcinoma using array-CGH and expression profiling identifies candidate cancer-associated genes in three amplified regions in high-grade tumors, including two 14-3-3 genes.
BMC Medical Genomics 2008, 1 :2
Genomic and transcription network analysis of siblings with and without MS defines two intersecting clusters of transcription factors, the larger of which is governed by upregulation of TCF2, a gene previously linked to diabetes.
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Research article
Investigating the complex genetic architecture of ankle-brachial index, a measure of peripheral arterial disease, in non-Hispanic whites Sharon LR Kardia, M Todd Greene, Eric Boerwinkle, Stephen T Turner, Iftikhar J Kullo BMC Medical Genomics 2008, 1 :16 (15 [Abstract ] [Provisional PDF ]
Research article
Classification of human cancers based on DNA copy number amplification modeling Samuel Myllykangas, Jarkko Tikka, Tom Bohling, Sakari Knuutila, Jaakko Hollmen BMC Medical Genomics 2008, 1 :15 (14 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice Nicole JW de Wit, Hanneke Bosch-Vermeulen, Philip J de Groot, Guido JEJ Hooiveld, Mechteld M Grootte Bromhaar, Jenny Jansen, Michael Muller, Roelof van der Meer BMC Medical Genomics 2008, 1 :14 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis Adam I Riker, Steven A Enkemann, Oystein Fodstad, Suhu Liu, Suping Ren, Christopher Morris, Yaguang Xi, Paul Howell, Brandon Metge, Rajeev S Samant, Lalita A Shevde, Wenbin Li, Steven Eschrich, Adil Daud, Jingfang Ju, Jaime Matta BMC Medical Genomics 2008, 1 :13 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Database
HIP2: An Online Database of Human Plasma Proteins from Healthy Individuals Sudipto Saha, Scott H Harrison, Changyu Shen, Haixu Tang, Predrag Radivojac, Randy J Arnold, Xiang Zhang, Jake Y Chen BMC Medical Genomics 2008, 1 :12 (25 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Cell cycle correlated genes dictate the prognostic power of breast cancer gene lists
Jonathan D Mosley, Ruth A Keri BMC Medical Genomics 2008, 1 :11 (25 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren's Contracture Latha Satish, William A LaFramboise, David B O'Gorman, Sandra Johnson, Benjamin Janto, Bing Siang Gan, Mark E Baratz, Fen Z Hu, J Christopher Post, Garth D Ehrlich, Sandeep Kathju BMC Medical Genomics 2008, 1 :10 (23 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Technical advance
Expression profiling with RNA from formalin-fixed, paraffin-embedded material Andrea Oberli, Vlad Popovici, Mauro Delorenzi, Anna Baltzer, Janine Antonov, Sybille Matthey, Stefan Aebi, Hans J BMC Medical Genomics 2008, 1 :9 (19 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Technical advance
Predictive gene lists for breast cancer prognosis: A topographic visualisation study Mingmanas Sivaraksa, David Lowe BMC Medical Genomics 2008, 1 :8 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of molecular pathways affected by pterostilbene, a natural dimethylether analog of resveratrol Zhiqiang Pan, Ameeta K Agarwal, Tao Xu, Qin Feng, Scott R Baerson, Stephen O Duke, Agnes M Rimando BMC Medical Genomics 2008, 1 :7 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Short Report
Detection of the transforming AKT1 mutation E17K in non-small cell lung cancer by high resolution melting Hongdo Do, Benjamin Solomon, Paul L Mitchell, Stephen B Fox, Alexander Dobrovic BMC Research Notes 2008, 1 :14 (16 [Abstract ] [Provisional PDF ]
Research article
Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays Hannah C Cheung, Keith A Baggerly, Spiridon Tsavachidis, Linda L Bachinski, Valerie L Neubauer, Tamara J Nixon, Kenneth D Aldape, Gilbert J Cote, Ralf Krahe BMC Genomics 2008, 9 :216 (12 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Identification of heterogeneity among soft tissue sarcomas by gene expression profiles from different tumors Keith M. Skubitz, Stefan Pambuccian, J. Carlos Manivel, Amy P. N. Skubitz Journal of Translational Medicine 2008, 6 :23 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Identification of novel vascular markers through gene expression profiling of tumor-derived endothelium Carmen Ghilardi, Giovanna Chiorino, Romina Dossi, Zsuzsanna Nagy, Raffaella Giavazzi, MariaRosa Bani BMC Genomics 2008, 9 :201 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Association between single nucleotide polymorphisms in the mu opioid receptor gene (OPRM1 ) and self-reported responses to alcohol in American Indians Cindy L Ehlers, Penelope A Lind, Kirk C Wilhelmsen BMC Medical Genetics 2008, 9 :35 (23 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Technical advance
Application of microarray outlier detection methodology to psychiatric research Carl Ernst, Alexandre Bureau, Gustavo Turecki BMC Psychiatry 2008, 8 :29 (23 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Conserved co-expression for candidate disease gene prioritization Martin Oti, Jeroen van Reeuwijk, Martijn A Huynen, Han G Brunner BMC Bioinformatics 2008, 9 :208 (23 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Unexpected structural complexity of supernumerary marker chromosomes characterized by microarray comparative genomic hybridization Karen D Tsuchiya, Kent E Opheim, Mark C Hannibal, Anne V Hing, Ian A Glass, Michael L Raff, Thomas Norwood, Beth A Torchia Molecular Cytogenetics 2008, 1 :7 (21 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
A gene sets approach for identifying prognostic gene signatures for outcome prediction Seon-Young Kim, Yong Sung Kim BMC Genomics 2008, 9 :177 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: Absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism Anne-Marie Cleton-Jansen, Ronald van Eijk, Marcel Lombaerts, Marjanka K Schmidt, Laura J Van't Veer, Katja Philippo, Rhyenne ME Zimmerman, Johannes L Peterse, Vincent TBHM Smit, Tom van Wezel, Cees J Cornelisse BMC Cancer 2008, 8 :105 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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