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Functional and epigenetics Section edited by George Ebers

This section considers studies of the expression and regulation of genes by genetic and epigenetic mechanisms, in relation to human health and disease.

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1.

Research article   Open Access

DNA methylation within the I.4 promoter region correlates with CYPl19A1 gene expression in human ex vivo mature omental and subcutaneous adipocytes

Joshua R Lewis, Tegan J McNab, Lawrence J Liew, Jeremy Tan, Phillip Hudson, Jenny Z Wang, Richard L Prince BMC Medical Genetics 2013, 14:87 (30 August 2013)

Abstract | Full text | PDF | ePUB

2.

Research article   Open Access Highly Accessed

DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets

Elin Hall, Tasnim Dayeh, Clare L Kirkpatrick, Claes B Wollheim, Marloes Dekker Nitert, Charlotte Ling BMC Medical Genetics 2013, 14:76 (23 July 2013)

Abstract | Full text | PDF | PubMed

3.

Research article   Open Access Highly Accessed

The promoter of miR-663 is hypermethylated in Chinese pediatric acute myeloid leukemia (AML)

Tao Yan-Fang, Ni Jian, Lu Jun, Wang Na, Xiao Pei-Fang, Zhao Wen-Li, Wu Dong, Pang Li, Wang Jian, Feng Xing, Pan Jian BMC Medical Genetics 2013, 14:74 (19 July 2013)

Abstract | Full text | PDF | PubMed

4.

Research article   Open Access Highly Accessed

Genetic interaction of GSH metabolic pathway genes in cystic fibrosis

Fernando Augusto Marson, Carmen Bertuzzo, Rodrigo Secolin, Antônio Ribeiro, José Ribeiro BMC Medical Genetics 2013, 14:60 (10 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

Research article   Open Access

Parent of origin influences the cardiac expression of vascular endothelial growth factor (Vegfa)

Christine L Chiu, Chloe T Morgan, Samantha J Lupton, Joanne M Lind BMC Medical Genetics 2013, 14:43 (5 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

6.

Research article   Open Access

Genome-wide methylation profiling of the bronchial mucosa of asthmatics: relationship to atopy

Yoon-Jeong Kim, Sung-Woo Park, Tae-Hoon Kim, Jong-Sook Park, Hyun Sub Cheong, Hyoung Doo Shin, Choon-Sik Park BMC Medical Genetics 2013, 14:39 (24 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

7.

Research article   Open Access Highly Accessed

Genome-wide analysis validates aberrant methylation in fragile X syndrome is specific to the FMR1 locus

Reid S Alisch, Tao Wang, Pankaj Chopra, Jeannie Visootsak, Karen N Conneely, Stephen T Warren BMC Medical Genetics 2013, 14:18 (29 January 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

Research article   Open Access

In-vitro characterization of novel and functional regulatory SNPs in the promoter region of IL2 and IL2R alpha in a Gabonese population

Xiangsheng Huang, Vera Kühne, Jürgen F J Kun, Peter T Soboslay, Bertrand Lell, Velavan TP BMC Medical Genetics 2012, 13:117 (7 December 2012)

Abstract | Full text | PDF | PubMed

9.

Research article   Open Access Highly Accessed

MAOA promoter methylation and susceptibility to carotid atherosclerosis: role of familial factors in a monozygotic twin sample

Jinying Zhao, Christopher W Forsberg, Jack Goldberg, Nicholas L Smith, Viola Vaccarino BMC Medical Genetics 2012, 13:100 (2 November 2012)

Abstract | Full text | PDF | PubMed

10.

Case report   Open Access

Beckwith Wiedemann imprinting defect found in leucocyte but not buccal DNA in a child born small for gestational age

Rinki Murphy, Deborah Mackay, Ed A Mitchell BMC Medical Genetics 2012, 13:99 (1 November 2012)

Abstract | Full text | PDF | PubMed

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