Impact of statin therapy on mortality in patients with sepsis-associated acute respiratory distress syndrome (ARDS) depends on ARDS severity: a prospective observational cohort study
BMC Medicine 2015, 13:128 (1 June 2015)
Patients with sepsis-associated acute respiratory distress syndrome (ARDS) on continuous statin therapy have lower 28-day mortality risk than those not taking statins, suggesting a survival benefit of statin therapy in this patient group.
Do statins increase and Mediterranean diet decrease the risk of breast cancer?
BMC Medicine 2014, 12:94 (5 June 2014)
This article is part of collection:
Metabolism, diet and...
Spotlight on breast cancer...
High intake of omega-3 relative to omega-6 lowers breast cancer risk; Michel de Lorgeril and Patricia Salen explore the link between diet and cancer, and discuss how statins can increase breast cancer risk through their effects on fatty acids.
Unintended effects of statins from observational studies in the general population: systematic review and meta-analysis
BMC Medicine 2014, 12:51 (22 March 2014)
Reporting of statin side effects in trials is limited, so a review and meta-analysis of observational studies provides evidence of a small risk of myopathy, raised liver enzymes and type 2 diabetes for cardiovascular events, but conclude the benefits of statins outweigh these observed harms.
The effect of statins on testosterone in men and women, a systematic review and meta-analysis of randomized controlled trials
BMC Medicine 2013, 11:57 (28 February 2013)
According to a meta-analysis, treatment with statins, a drug commonly prescribed to patients at risk of cardiovascular disease, can reduce testosterone levels in both men and women, although the cause for this needs to be determined by further studies.
Recent findings on the health effects of omega-3 fatty acids and statins, and their interactions: do statins inhibit omega-3?
BMC Medicine 2013, 11:5 (4 January 2013)
This article is part of a collection on
Metabolism, diet and...
Michel de Lorgeril and colleagues review contrasting evidence on the health benefits of omega-3 fatty acids (n-3), and discuss how n-3 may be ineffective in statin users due to complex interactions between the two compounds.
The impact of statins on psychological wellbeing: a systematic review and meta-analysis
BMC Medicine 2012, 10:154 (3 December 2012)
Evidence from a systematic review and meta-analysis reveals mood-related benefits of statins, refuting previous data showing they have adverse effects, and suggests that future trials should examine this effect in patients with depression.