A diagnostic window for the treatment of acute graft-versus-host disease prior to visible clinical symptoms in a murine model
BMC Medicine 2013, 11:134 (21 May 2013)
Alloreactive T cells are present in the blood 2 weeks before the onset of acute graft-versus-host disease (GVHD) symptoms in a mouse model, suggesting these cells could be measured to allow early diagnosis and timely therapeutic intervention.
Toward the future of psychiatric diagnosis: the seven pillars of RDoC
BMC Medicine 2013, 11:126 (14 May 2013)
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Bruce Cuthbert and Thomas Insel argue that future psychiatric nosologies will be informed by the Research Domain Criteria (RDoC) that is based on genetics, neuroscience and behavioural science, which will help achieve precision medicine for mental disorders.
Shifting from glucose diagnosis to the new HbA1c diagnosis reduces the capability of the Finnish Diabetes Risk Score (FINDRISC) to screen for glucose abnormalities within a real-life primary healthcare preventive strategy
BMC Medicine 2013, 11:45 (21 February 2013)
The predictive ability of a screening tool for diabetes is reduced when the proposed new hemoglobin-based criteria are used for diagnosis instead of glucose, suggesting that glucose should be measured to assess diabetes risk using this score.