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	1. 80866 Accesses	Research article Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition Sabine Rohrmann, Kim Overvad, H Bueno-de-Mesquita, Marianne U Jakobsen, Rikke Egeberg, Anne Tjønneland, Laura Nailler, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Vittorio Krogh, Domenico Palli, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Manuela M Bergmann, Heiner Boeing, Kuanrong Li, Rudolf Kaaks, Kay-Tee Khaw, Nicholas J Wareham, Francesca L Crowe, Timothy J Key, Androniki Naska, Antonia Trichopoulou, Dimitirios Trichopoulos, Max Leenders, Petra HM Peeters, Dagrun Engeset, Christine L Parr, Guri Skeie et al. BMC Medicine 2013, 11:63 (7 March 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary A large study finds a positive association between processed meat consumption and mortality due to cardiovascular disease and cancer, indicating that reducing the amount of processed meat in the diet could reduce mortality risk.
	2. 41076 Accesses	Opinion Spectrum of gluten-related disorders: consensus on new nomenclature and classification Anna Sapone, Julio C Bai, Carolina Ciacci, Jernej Dolinsek, Peter HR Green, Marios Hadjivassiliou, Katri Kaukinen, Kamran Rostami, David S Sanders, Michael Schumann, Reiner Ullrich, Danilo Villalta, Umberto Volta, Carlo Catassi, Alessio Fasano BMC Medicine 2012, 10:13 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Fasano and colleagues propose new nomenclature and classifications within the spectrum of gluten-related disorders (GRDs), prompted by indications from the past decade that reactions to gluten may be caused by conditions other than celiac disease.
	3. 32301 Accesses	Research article Mental illness related disparities in diabetes prevalence, quality of care and outcomes: a population-based longitudinal study Qun Mai, C D'Arcy J Holman, Frank M Sanfilippo, Jonathan D Emery, David B Preen BMC Medicine 2011, 9:118 (1 November 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Disparities in diabetes prevalence and the quality and outcome of diabetic care of those with mental illness and those without in Australia highlights the need for better, more integrated care for this population.
	4. 21567 Accesses	Research article Anatomy of open access publishing: a study of longitudinal development and internal structure Mikael Laakso, Bo-Christer Björk BMC Medicine 2012, 10:124 (22 October 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The landscape of scientific publishing has changed during the last decade due to steady growth of open access (OA) journals, as the volume of scientific articles published between 2000-2011 in full immediate OA journals has grown rapidly in relative annual share of published journal articles.
	5. 21065 Accesses	Research article Cross-national epidemiology of DSM-IV major depressive episode Evelyn Bromet, Laura Andrade, Irving Hwang, Nancy A Sampson, Jordi Alonso, Giovanni de Girolamo, Ron de Graaf, Koen Demyttenaere, Chiyi Hu, Noboru Iwata, Aimee N Karam, Jagdish Kaur, Stanislav Kostyuchenko, Jean-Pierre Lépine, Daphna Levinson, Herbert Matschinger, Maria Mora, Mark Browne, Jose Posada-Villa, Maria Viana, David R Williams, Ronald C Kessler BMC Medicine 2011, 9:90 (26 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Major depression is a significant public health problem around the globe which affects women twice as commonly as men and is most strongly correlated with being separated, divorced or widowed.
	6. 17387 Accesses	Review Procalcitonin for diagnosis of infection and guide to antibiotic decisions: past, present and future Philipp Schuetz, Werner Albrich, Beat Mueller BMC Medicine 2011, 9:107 (22 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mueller and colleagues kick off our new thematic series on Clinical Biomarkers with a review on the utility of procalcitonin in the diagnosis of bacterial infection and decisions about antibiotic treatment in different clinical settings.
	7. 16242 Accesses	Research article Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity Anna Sapone, Karen M Lammers, Vincenzo Casolaro, Marcella Cammarota, Maria Giuliano, Mario De Rosa, Rosita Stefanile, Giuseppe Mazzarella, Carlo Tolone, Maria Russo, Pasquale Esposito, Franca Ferraraccio, Maria Cartenì, Gabriele Riegler, Laura de Magistris, Alessio Fasano BMC Medicine 2011, 9:23 (9 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Celiac disease and gluten sensitivity sufferers have similar pathologies triggered by gluten ingestion, but have different mucosal immune profiles and gut permeabilities, which may explain the less severe pathology of gluten sensitivity as compared to celiac disease.
	8. 15728 Accesses	Research article Perinatal nicotine exposure induces asthma in second generation offspring Virender K Rehan, Jie Liu, Erum Naeem, Jia Tian, Reiko Sakurai, Kenny Kwong, Omid Akbari, John S Torday BMC Medicine 2012, 10:129 (30 October 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Smoking during pregnancy induces asthma in offspring, and the effects are permanently transmitted to subsequent generations via epigenetic changes in germ cells, providing a breakthrough in studying transgenerational effects of toxins.
	9. 14938 Accesses	Research article Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study Verena Sengpiel, Elisabeth Elind, Jonas Bacelis, Staffan Nilsson, Jakob Grove, Ronny Myhre, Margaretha Haugen, Helle Meltzer, Jan Alexander, Bo Jacobsson, Anne-Lise Brantsæter BMC Medicine 2013, 11:42 (19 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Caffeine intake from various sources during pregnancy is associated with increased risk of the baby being small for gestational age and decreased birth weight, which may have implications for the recommended consumption of caffeine.
	10. 14180 Accesses	Minireview Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis Niels Høiby BMC Medicine 2011, 9:32 (4 April 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Hoiby reviews recent advances in treatment of chronic Pseudomonas aeruginosa lung infection due to biofilm formation in cystic fibrosis patients, with a focus on inhalation therapy targeted towards prophylaxis and chronic suppressive therapy.
	11. 14040 Accesses	Research article Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells Yong Zhao, Zhaoshun Jiang, Tingbao Zhao, Mingliang Ye, Chengjin Hu, Zhaohui Yin, Heng Li, Ye Zhang, Yalin Diao, Yunxiang Li, Yingjian Chen, Xiaoming Sun, Mary Fisk, Randal Skidgel, Mark Holterman, Bellur Prabhakar, Theodore Mazzone BMC Medicine 2012, 10:3 (10 January 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The safe reversal of Type 1 diabetes is possible with Stem Cell Educator therapy which uses stem cells from cord blood to re-educate a diabetic's own T cells, restarts pancreatic function, and reduces the need for insulin.
	12. 13935 Accesses	Research article Open access versus subscription journals: a comparison of scientific impact Bo-Christer Björk, David Solomon BMC Medicine 2012, 10:73 (17 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| f1000 \| Editor’s summary The scientific impact of articles published in open access (OA) and subscription journals are similar when journal discipline, location of publisher and age of publication are compared, which is particularly true in medicine and health, where OA journals founded in the last 10 years receive on average as many citations as subscription journals launched during the same time.
	13. 13924 Accesses	Minireview Understanding the benefit of metformin use in cancer treatment Ryan JO Dowling, Pamela J Goodwin, Vuk Stambolic BMC Medicine 2011, 9:33 (6 April 2011) Abstract \| Full text \| PDF \| PubMed \| 1 comment \| Editor’s summary Metformin has long been known to combat diabetes, but its mechanisms of action are now known to also provide potent anti-tumor action, reviewed here by Stambolic and colleagues.
	14. 12064 Accesses	Correspondence CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials Kenneth F Schulz, Douglas G Altman, David Moher, the CONSORT Group BMC Medicine 2010, 8:18 (24 March 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The latest version of the CONSORT statement, used worldwide to help improve the reporting of randomized controlled trials, updates the reporting guidelines based on new methodological evidence and amassed experience.
	15. 13767 Accesses	Research article Alcohol intake, wine consumption and the development of depression: the PREDIMED study Alfredo Gea, Juan J Beunza, Ramón Estruch, Almudena Sánchez-Villegas, Jordi Salas-Salvadó, Pilar Buil-Cosiales, Enrique Gómez-Gracia, María-Isabel Covas, Dolores Corella, Miquel Fiol, Fernando Arós, José Lapetra, Rosa-María Lamuela-Raventós, Julia Wärnberg, Xavier Pintó, Lluis Serra-Majem, Miguel A Martínez-González, for the PREDIMED GROUP BMC Medicine 2013, 11:192 (30 August 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Moderate consumption of alcohol, specifically wine, is associated with lower incidence of depression in a Mediterranean population, suggesting that those who drink two to seven drinks per week may be less likely to be depressed in comparison to abstainers.
	16. 11560 Accesses	Minireview Advances in understanding and treating ADHD Kevin M Antshel, Teresa M Hargrave, Mihai Simonescu, Prashant Kaul, Kaitlin Hendricks, Stephen V Faraone BMC Medicine 2011, 9:72 (10 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Antshel and colleagues review the advances over the past decade in the understanding and treatment of Attention Deficit Hyperactivity Disorder (ADHD), which comprise both tailored stimulant formulations and cognitive behavioral interventions.
	17. 11441 Accesses	Research article The Alvarado score for predicting acute appendicitis: a systematic review Robert Ohle, Fran O'Reilly, Kirsty K O'Brien, Tom Fahey, Borislav D Dimitrov BMC Medicine 2011, 9:139 (28 December 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The Alvarado score is a ten-point clinical scoring system used to stratify patients with suspected appendicitis, and a systematic review shows that in all patient groups, the score is useful in ruling out appendicitis at a cut point of 5 five or below.
	18. 11322 Accesses	Review Clinical trials for stem cell therapies Alan Trounson, Rahul G Thakar, Geoff Lomax, Don Gibbons BMC Medicine 2011, 9:52 (10 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Trounson and colleagues review recent developments and future prospects of clinical trials for stem cell therapies, highlighting usage of mesenchymal and neural stem cells, and reporting on the start of trials involving lines derived from pluripotent cells.
	19. 10379 Accesses	Review Bone regeneration: current concepts and future directions Rozalia Dimitriou, Elena Jones, Dennis McGonagle, Peter V Giannoudis BMC Medicine 2011, 9:66 (31 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Peter Giannoudis and colleagues review current strategies used to enhance bone regeneration in cases of extensive trauma and abnormalities , and predict that tissue engineering and gene therapy that may overcome limitations to current treatments.
	20. 10087 Accesses	Research article Depression, antidepressant medications, and risk of Clostridium difficile infection Mary A M Rogers, M Todd Greene, Vincent B Young, Sanjay Saint, Kenneth M Langa, John Y Kao, David M Aronoff BMC Medicine 2013, 11:121 (7 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The risk of Clostridium difficile infection is increased in adults with depression and in those taking antidepressants during hospitalization, indicating that physicians should be aware of the elevated infection risk in these patients.
	21. 10084 Accesses	Review Metabolic syndrome: definitions and controversies Eva Kassi, Panagiota Pervanidou, Gregory Kaltsas, George Chrousos BMC Medicine 2011, 9:48 (5 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary George Chrousos and colleagues provide a critical review of the definitions of Metabolic Syndrome (MetS), discussing the controversies surrounding this complex disorder, particularly how child and adulthood MetS differ.
	22. 9330 Accesses	Commentary Medicine, morality and health care social media Farris K Timimi BMC Medicine 2012, 10:83 (2 August 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Farris Timimi comments on the growing popularity of social media, and discusses how this can be used as an effective tool for physicians to help patients gain better understanding about clinical research.
	23. 9007 Accesses	Review Managing hyperemesis gravidarum: a multimodal challenge JK Jueckstock, R Kaestner, I Mylonas BMC Medicine 2010, 8:46 (15 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Better understanding by medical personnel of the etiology and diagnosis of hyperemesis gravidarum, a severe or prolonged form of the nausea and vomiting experienced by pregnant women, would help management and treatment of this condition.
	24. 8919 Accesses	Research article A stable pattern of EEG spectral coherence distinguishes children with autism from neuro-typical controls - a large case control study Frank H Duffy, Heidelise Als BMC Medicine 2012, 10:64 (26 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A large scale study assessing electroencephalography (EEG) patterns in children diagnosed with autism and matched controls identifies differences between these groups, which could be used to provide an EEG signature for autism diagnosis.
	25. 8758 Accesses	Opinion Tackling overweight and obesity: does the public health message match the science? Katherine Hafekost, David Lawrence, Francis Mitrou, Therese A O'Sullivan, Stephen R Zubrick BMC Medicine 2013, 11:41 (18 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Many weight-loss interventions based on a simple model of energy balance fail to achieve long-term results; Stephen R Zubrick and colleagues recommend that multiple factors affecting energy regulation should be considered in order to tackle obesity.