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	1. 13767 Accesses	Research article Alcohol intake, wine consumption and the development of depression: the PREDIMED study Alfredo Gea, Juan J Beunza, Ramón Estruch, Almudena Sánchez-Villegas, Jordi Salas-Salvadó, Pilar Buil-Cosiales, Enrique Gómez-Gracia, María-Isabel Covas, Dolores Corella, Miquel Fiol, Fernando Arós, José Lapetra, Rosa-María Lamuela-Raventós, Julia Wärnberg, Xavier Pintó, Lluis Serra-Majem, Miguel A Martínez-González, for the PREDIMED GROUP BMC Medicine 2013, 11:192 (30 August 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Moderate consumption of alcohol, specifically wine, is associated with lower incidence of depression in a Mediterranean population, suggesting that those who drink two to seven drinks per week may be less likely to be depressed in comparison to abstainers.
	2. 7908 Accesses	Opinion Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics Gerwyn Morris, Michael Maes BMC Medicine 2013, 11:205 (17 September 2013) Abstract \| Full text \| PDF \| 1 comment \| Editor’s summary As multiple sclerosis (MS) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) share many symptoms and neuro-immune characteristics, Gerwyn Morris and Michael Maes suggest that CFS should be considered as a neuro-immune disease and that MS patients may be susceptible to develop CFS symptoms.
	3. 4447 Accesses	Opinion So depression is an inflammatory disease, but where does the inflammation come from? Michael Berk, Lana J Williams, Felice N Jacka, Adrienne O’Neil, Julie A Pasco, Steven Moylan, Nicholas B Allen, Amanda L Stuart, Amie C Hayley, Michelle L Byrne, Michael Maes BMC Medicine 2013, 11:200 (12 September 2013) Abstract \| Full text \| PDF \| Editor’s summary Depression is associated with a low-grade inflammatory response; Michael Berk and colleagues discuss the sources of inflammation, oxidative and nitrosative stress in depression and emphasize that these factors can be treated or prevented.
	4. 3893 Accesses	Opinion Spectrum of gluten-related disorders: consensus on new nomenclature and classification Anna Sapone, Julio C Bai, Carolina Ciacci, Jernej Dolinsek, Peter HR Green, Marios Hadjivassiliou, Katri Kaukinen, Kamran Rostami, David S Sanders, Michael Schumann, Reiner Ullrich, Danilo Villalta, Umberto Volta, Carlo Catassi, Alessio Fasano BMC Medicine 2012, 10:13 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Fasano and colleagues propose new nomenclature and classifications within the spectrum of gluten-related disorders (GRDs), prompted by indications from the past decade that reactions to gluten may be caused by conditions other than celiac disease.
	5. 3307 Accesses	Research article A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways Robert P Anderson, Margaret J Henry, Roberta Taylor, Emma L Duncan, Patrick Danoy, Marylia J Costa, Kathryn Addison, Jason A Tye-Din, Mark A Kotowicz, Ross E Knight, Wendy Pollock, Geoffrey C Nicholson, Ban-Hock Toh, Matthew A Brown, Julie A Pasco BMC Medicine 2013, 11:188 (28 August 2013) Abstract \| Full text \| PDF \| Editor’s summary A novel screening approach involving human leukocyte antigen (HLA)-DQ gene testing and confirmatory serology accurately estimates the prevalence of celiac disease (CD), and could help to reduce the number of unnecessary gastroscopies.
	6. 3241 Accesses	Forum DSM-5: a collection of psychiatrist views on the changes, controversies, and future directions Charles B Nemeroff, Daniel Weinberger, Michael Rutter, Harriet L MacMillan, Richard A Bryant, Simon Wessely, Dan J Stein, Carmine M Pariante, Florian Seemüller, Michael Berk, Gin S Malhi, Martin Preisig, Martin Brüne, Paul Lysaker BMC Medicine 2013, 11:202 (12 September 2013) Abstract \| Full text \| PDF \| Editor’s summary Our Editorial Board Members and their colleagues discuss their personal views on the newly released fifth version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), specifically with regard to how it may, or may not, affect their specific areas of psychiatric medicine.
	7. 3168 Accesses	Minireview What is next after the genes for autoimmunity? John Castiblanco, Mauricio Arcos-Burgos, Juan-Manuel Anaya BMC Medicine 2013, 11:197 (4 September 2013) Abstract \| Full text \| PDF \| Editor’s summary Autoimmune diseases have complex etiology and are known to aggregate in families; Juan-Manuel Anaya and colleagues review the genetic components of autoimmunity and discuss the challenges associated with genetic analysis and disease prediction.
	8. 2275 Accesses	Research article Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition Sabine Rohrmann, Kim Overvad, H Bueno-de-Mesquita, Marianne U Jakobsen, Rikke Egeberg, Anne Tjønneland, Laura Nailler, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Vittorio Krogh, Domenico Palli, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Manuela M Bergmann, Heiner Boeing, Kuanrong Li, Rudolf Kaaks, Kay-Tee Khaw, Nicholas J Wareham, Francesca L Crowe, Timothy J Key, Androniki Naska, Antonia Trichopoulou, Dimitirios Trichopoulos, Max Leenders, Petra HM Peeters, Dagrun Engeset, Christine L Parr, Guri Skeie et al. BMC Medicine 2013, 11:63 (7 March 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary A large study finds a positive association between processed meat consumption and mortality due to cardiovascular disease and cancer, indicating that reducing the amount of processed meat in the diet could reduce mortality risk.
	9. 2249 Accesses	Research article Mental illness related disparities in diabetes prevalence, quality of care and outcomes: a population-based longitudinal study Qun Mai, C D'Arcy J Holman, Frank M Sanfilippo, Jonathan D Emery, David B Preen BMC Medicine 2011, 9:118 (1 November 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Disparities in diabetes prevalence and the quality and outcome of diabetic care of those with mental illness and those without in Australia highlights the need for better, more integrated care for this population.
	10. 2087 Accesses	Research article Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III Xinqing Deng, Yiqing Song, JoAnn E Manson, Lisa B Signorello, Shumin M Zhang, Martha J Shrubsole, Reid M Ness, Douglas L Seidner, Qi Dai BMC Medicine 2013, 11:187 (27 August 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Evidence from the National Health and Nutrition Examination Surveys shows high intake of magnesium is inversely associated with vitamin D insufficiency, and may protect against mortality, although confirmation from clinical trials is needed.
	11. 1994 Accesses	Research article Effect of the Mediterranean diet on blood pressure in the PREDIMED trial: results from a randomized controlled trial Estefania Toledo, Frank B Hu, Ramon Estruch, Pilar Buil-Cosiales, Dolores Corella, Jordi Salas-Salvadó, M Covas, Fernando Arós, Enrique Gómez-Gracia, Miquel Fiol, Jose Lapetra, Luis Serra-Majem, Xavier Pinto, Rosa M Lamuela-Raventós, Guillermo Saez, Mònica Bulló, Valentina Ruiz-Gutiérrez, Emilio Ros, José V Sorli, Miguel Martinez-Gonzalez BMC Medicine 2013, 11:207 (19 September 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary In individuals with high cardiovascular disease risk, eating a Mediterranean diet supplemented with olive oil or nuts reduces diastolic blood pressure (BP) more than a low-fat diet, suggesting the Mediterranean diet could be beneficial for BP control.
	12. 1877 Accesses	Research article Associations between smoking, components of metabolic syndrome and lipoprotein particle size Sandra N Slagter, Jana Vliet-Ostaptchouk, Judith M Vonk, H Boezen, Robin PF Dullaart, Anneke C Muller Kobold, Edith J Feskens, André Beek, Melanie Klauw, Bruce HR Wolffenbuttel BMC Medicine 2013, 11:195 (3 September 2013) Abstract \| Full text \| PDF \| Editor’s summary Smoking is associated with increased prevalence of metabolic syndrome irrespective of sex or body mass index, and the association is related to lipid changes, providing a mechanism linking smoking to increased risk of cardiovascular disease.
	13. 1762 Accesses	Research article Cross-national epidemiology of DSM-IV major depressive episode Evelyn Bromet, Laura Andrade, Irving Hwang, Nancy A Sampson, Jordi Alonso, Giovanni de Girolamo, Ron de Graaf, Koen Demyttenaere, Chiyi Hu, Noboru Iwata, Aimee N Karam, Jagdish Kaur, Stanislav Kostyuchenko, Jean-Pierre Lépine, Daphna Levinson, Herbert Matschinger, Maria Mora, Mark Browne, Jose Posada-Villa, Maria Viana, David R Williams, Ronald C Kessler BMC Medicine 2011, 9:90 (26 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Major depression is a significant public health problem around the globe which affects women twice as commonly as men and is most strongly correlated with being separated, divorced or widowed.
	14. 1757 Accesses	Review Rapid diagnostics of tuberculosis and drug resistance in the industrialized world: clinical and public health benefits and barriers to implementation Francis Drobniewski, Vladyslav Nikolayevskyy, Horst Maxeiner, Yanina Balabanova, Nicola Casali, Irina Kontsevaya, Olga Ignatyeva BMC Medicine 2013, 11:190 (29 August 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Francis Drobniewski and colleagues review new technologies for the diagnosis of tuberculosis (TB) and drug resistance of immunocompetent patients in the industrialized world, and consider cost-effectiveness, implementation and impact on public health.
	15. 1728 Accesses	Review Pharmacological treatments in ARDS; a state-of-the-art update Andrew Boyle, Rob Sweeney, Daniel McAuley BMC Medicine 2013, 11:166 (20 August 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Current treatment of acute respiratory distress syndrome (ARDS) is limited to minimizing potentially harmful ventilation; Daniel McAuley and colleagues review clinical trials of new agents for ARDS and discuss emerging pharmacological therapies.
	16. 1607 Accesses	Research article Mediterranean dietary pattern and depression: the PREDIMED randomized trial Almudena Sánchez-Villegas, Miguel Martínez-González, Ramón Estruch, Jordi Salas-Salvadó, Dolores Corella, Maria Covas, Fernando Arós, Dora Romaguera, Enrique Gómez-Gracia, José Lapetra, Xavier Pintó, Jose Martínez, Rosa Lamuela-Raventós, Emilio Ros, Alfredo Gea, Julia Wärnberg, Lluis Serra-Majem BMC Medicine 2013, 11:208 (20 September 2013) Abstract \| Full text \| PDF \| Editor’s summary Patients with high cardiovascular disease risk and type 2 diabetes on a Mediterranean diet supplemented with nuts have lower risk of depression than those on a low-fat diet, suggesting nuts have a beneficial effect on mental health in this population.
	17. 1517 Accesses	Research article Systematic review of clinical practice guidelines in the diagnosis and management of thyroid nodules and cancer Tsai-Wei Huang, Jun-Hung Lai, Mei-Yi Wu, Shiah-Lian Chen, Chih-Hsiung Wu, Ka-Wai Tam BMC Medicine 2013, 11:191 (29 August 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Although clinical practice guidelines (CPGs) are used to diagnose and manage thyroid nodules and cancer, a systematic review finds that recommendations across international CPGs vary in methodological quality, highlighting the need for improvement in the quality of these guidelines.
	18. 1460 Accesses	Research article Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial Marta Guasch-Ferré, Mònica Bulló, Miguel Martínez-González, Emilio Ros, Dolores Corella, Ramon Estruch, Montserrat Fitó, Fernando Arós, Julia Wärnberg, Miquel Fiol, José Lapetra, Ernest Vinyoles, Rosa Lamuela-Raventós, Lluís Serra-Majem, Xavier Pintó, Valentina Ruiz-Gutiérrez, Josep Basora, Jordi Salas-Salvadó, on behalf of the PREDIMED study group BMC Medicine 2013, 11:164 (16 July 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A large trial in a Mediterranean population finds an inverse trend between regular nut consumption and mortality in individuals with high cardiovascular risk, and suggests that nuts but not olive oil, may also have a protective effect on premature mortality in individuals.
	19. 1456 Accesses	Commentary Is it smoking or related lifestyle variables that increase metabolic syndrome risk? Mikael Rabaeus, Patricia Salen, Michel de Lorgeril BMC Medicine 2013, 11:196 (3 September 2013) Abstract \| Full text \| PDF \| Editor’s summary Michel de Lorgeril and colleagues comment on a study showing that smoking is associated with metabolic syndrome (MetS), and discuss how other lifestyle factors such as physical inactivity and alcohol consumption could explain the link.
	20. 1453 Accesses	Research article Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study Mora Murri, Isabel Leiva, Juan Miguel Gomez-Zumaquero, Francisco J Tinahones, Fernando Cardona, Federico Soriguer, María Isabel Queipo-Ortuño BMC Medicine 2013, 11:46 (21 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Gut microbiota are present at lower quantity and have different composition in children with type 1 diabetes compared with healthy children, possibly due to altered gut permeability, and modification of these bacteria could control diabetes development.
	21. 1444 Accesses	Research article α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation Masa-Aki Shibata, Munekazu Iinuma, Junji Morimoto, Hitomi Kurose, Kanako Akamatsu, Yasushi Okuno, Yukihiro Akao, Yoshinori Otsuki BMC Medicine 2011, 9:69 (3 June 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Alpha-mangostin, an extract from the mangosteen fruit, demonstrates antitumor growth and antimetastatic activities by decreasing Akt phosphorylation levels in a mouse model of breast cancer and therefore may have clinical applications.
	22. 1285 Accesses	Research article The relationship of Asperger’s syndrome to autism: a preliminary EEG coherence study Frank H Duffy, Aditi Shankardass, Gloria B McAnulty, Heidelise Als BMC Medicine 2013, 11:175 (31 July 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary EEG-derived measures of brain connectivity show that Asperger's syndrome and autism in children are closely related, but there are neurophysiological differences between the groups, suggesting that Asperger’s should be considered a separate entity.
	23. 1237 Accesses	Research article Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity Anna Sapone, Karen M Lammers, Vincenzo Casolaro, Marcella Cammarota, Maria Giuliano, Mario De Rosa, Rosita Stefanile, Giuseppe Mazzarella, Carlo Tolone, Maria Russo, Pasquale Esposito, Franca Ferraraccio, Maria Cartenì, Gabriele Riegler, Laura de Magistris, Alessio Fasano BMC Medicine 2011, 9:23 (9 March 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Celiac disease and gluten sensitivity sufferers have similar pathologies triggered by gluten ingestion, but have different mucosal immune profiles and gut permeabilities, which may explain the less severe pathology of gluten sensitivity as compared to celiac disease.
	24. 1210 Accesses	Question and Answer DSM-5 and ADHD – an interview with Eric Taylor Eric Taylor BMC Medicine 2013, 11:204 (12 September 2013) Abstract \| Full text \| PDF \| Editor’s summary In this Q&A audio podcast, we interview child and adolescent psychiatrist Eric Taylor about the revisions to the diagnosis of attention deficit hyperactivity disorder (ADHD) in DSM-5, and explore how these changes will affect clinical practice.
	25. 1198 Accesses	Research article Comparing sociocultural features of cholera in three endemic African settings Christian Schaetti, Neisha Sundaram, Sonja Merten, Said M Ali, Erick O Nyambedha, Bruno Lapika, Claire-Lise Chaignat, Raymond Hutubessy, Mitchell G Weiss BMC Medicine 2013, 11:206 (18 September 2013) Abstract \| Provisional PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Investigation into sociocultural features of endemic cholera in three African countries finds both common and distinct health-seeking and knowledge patterns, which could be used to guide planning for future cholera control and elimination.