BMC Medicine | All articles

Submit a manuscript Register Contact us Follow us on Twitter

Explore BMC Medicine

Advertisement

Articles

Display/download options Articles per page: 25 | 50 | 100

Display options

Editor's summary Citation

Download options

Send
To

	All
		Research article Sodium vanadate combined with L-ascorbic acid delays disease progression, enhances motor performance, and ameliorates muscle atrophy and weakness in mice with spinal muscular atrophy Huei-Chun Liu, Chen-Hung Ting, Hsin-Lan Wen, Li-Kai Tsai, Hsiu-Mei Hsieh-Li, Hung Li, Sue Lin-Chao BMC Medicine 2013, 11:38 (14 February 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Combined therapy of sodium vanadate with L-ascorbic acid delays disease progression and enhances motor performance in mice, as well as reducing toxicity, indicating an improved strategy for treating of late onset spinal muscular atrophy (SMA)
		Review Peri-operative interventions producing better functional outcomes and enhanced recovery following total hip and knee arthroplasty: an evidence-based review Mazin S Ibrahim, Muhammad A Khan, Ikram Nizam, Fares S Haddad BMC Medicine 2013, 11:37 (13 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Fares Haddad and colleagues review peri-operative interventions for improved patient outcomes after total knee and hip replacements, which aim to improve patient quality of life and lessen the economic burden by reducing length of hospital stay.
		Commentary A practical method to target individuals for outbreak detection and control Gerardo Chowell, Cécile Viboud BMC Medicine 2013, 11:36 (12 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Gerardo Chowell and Cécile Viboud comment on a novel method that identifies risk of influenza transmission and allows early detection of infection in schools, but caution that this promising method needs testing on outbreaks in different settings.
		Research article A low-cost method to assess the epidemiological importance of individuals in controlling infectious disease outbreaks Timo Smieszek, Marcel Salathé BMC Medicine 2013, 11:35 (12 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A low-cost ranking method for modeling the spread of influenza in schools identifies subpopulations at higher risk of early infection than randomly selected communities, which could be effective for predicting and preventing epidemics.
		Commentary Managing the risk of lithium-induced nephropathy in the long-term treatment of patients with recurrent affective disorders Emanuel Severus, Michael Bauer BMC Medicine 2013, 11:34 (11 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Emanuel Severus and Michael Bauer comment on recent research that showed kidney toxicity is associated with duration of lithium treatment and age, and discuss the importance of managing renal function in patients on long-term lithium therapy.
		Research article Duration of lithium treatment is a risk factor for reduced glomerular function: a cross-sectional study Alberto Bocchetta, Raffaella Ardau, Paolo Carta, Franca Ligas, Claudia Sardu, Antonello Pani, Maria Del Zompo BMC Medicine 2013, 11:33 (11 February 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In patients with affective disorders, the duration of lithium treatment and advanced age are risk factors for glomerular failure, suggesting that kidney toxicity should be weighed against the protective effects of lithium in these patients.
		Research article The effects of apoptosis vulnerability markers on the myocardium in depression after myocardial infarction Yiming Wang, Xingde Liu, Dongfeng Zhang, Jianhui Chen, Shuzheng Liu, Michael Berk BMC Medicine 2013, 11:32 (8 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Pro-apoptotic pathways in the heart are upregulated in rats that have suffered post-myocardial infarction (MI) depression, and these pathophysiological processes may underlie the increased incidence of depression in patients following MI.
		Review The sweet and sour of serological glycoprotein tumor biomarker quantification Uros Kuzmanov, Hari Kosanam, Eleftherios P Diamandis BMC Medicine 2013, 11:31 (7 February 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary As there has been limited success in the development of glycoprotein tumor markers, Eleftherios Diamandis and colleagues review the challenges, and discuss how new technology will facilitate quantification of these biomarkers for clinical use.
		Commentary Fat dads must not be blamed for their children's health problems Gudrun E Moore, Philip Stanier BMC Medicine 2013, 11:30 (6 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Gudrun Moore and Philip Stainer comment on a recent study showing that fathers’ obesity is related to gene methylation changes in offspring, but highlight that the results should not be over-emphasized and future studies should consider whole genomes.
		Research article Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort Adelheid Soubry, Joellen M Schildkraut, Amy Murtha, Frances Wang, Zhiqing Huang, Autumn Bernal, Joanne Kurtzberg, Randy L Jirtle, Susan K Murphy, Cathrine Hoyo BMC Medicine 2013, 11:29 (6 February 2013) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology \| Editor’s summary Obesity in fathers is associated with a decrease in methylation of the insulin-like growth factor 2 gene in their newborns, suggesting that paternal obesity may disrupt normal imprinting in germ cells and affect the health of their offspring.
		Review Depression pathogenesis and treatment: what can we learn from blood mRNA expression? Nilay Hepgul, Annamaria Cattaneo, Patricia A Zunszain, Carmine M Pariante BMC Medicine 2013, 11:28 (5 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Carmine Pariante and colleagues review the altered pattern of peripheral gene expression in patients with major depressive disorder, and comment on the clinical applicability of potential biomarkers to measure these reversible changes in patients.
		Commentary Multigenerational epigenetic effects of nicotine on lung function Frances M Leslie BMC Medicine 2013, 11:27 (4 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A recent study in rats showed nicotine exposure during pregnancy results in significant multigenerational effects; in light of these findings Frances Leslie discusses the importance of effective smoking cessation strategies during pregnancy.
		Minireview Epigenetic mechanisms in migraine: a promising avenue? Else Eising, Nicole A Datson, Arn MJM van den Maagdenberg, Michel D Ferrari BMC Medicine 2013, 11:26 (4 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Michel Ferrari and colleagues review the evidence for potential epigenetic mechanisms behind migraine pathology, which may provide therapeutic targets for novel prophylactic strategies.
		Research article Genetic discrimination and life insurance: a systematic review of the evidence Yann Joly, Ida Ngueng Feze, Jacques Simard BMC Medicine 2013, 11:25 (31 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Evidence from a systematic review of genetic discrimination studies shows that individual cases of discrimination exist in the context of life insurance, but policy action cannot be justified at present due to limitations of the studies.
		Research article The global burden of neonatal hypothermia: systematic review of a major challenge for newborn survival Karsten Lunze, David E Bloom, Dean T Jamison, Davidson H Hamer BMC Medicine 2013, 11:24 (31 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Evidence from a systematic review shows that neonatal hypothermia indirectly contributes to infant mortality, suggesting that hypothermia prevention measures should be employed to help reduce newborn deaths in resource-limited settings.
		Correspondence Economic analyses to support decisions about HPV vaccination in low- and middle-income countries: a consensus report and guide for analysts Mark Jit, Carol Levin, Marc Brisson, Ann Levin, Stephen Resch, Johannes Berkhof, Jane Kim, Raymond Hutubessy BMC Medicine 2013, 11:23 (30 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary An expert group from the World Health Organization provides advice on economic issues associated with human papillomavirus (HPV) vaccination in low- and middle-income countries (LMICs), recommending that analyses are thorough, but not overly complex.
		Commentary Meta-narrative and realist reviews: guidance, rules, publication standards and quality appraisal David Gough BMC Medicine 2013, 11:22 (29 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary David Gough comments on the release of the RAMESES publication reporting standards, and emphasizes the importance of applying rigorous research methods, whilst also maintaining quality appraisal and transparency.
		Guideline RAMESES publication standards: realist syntheses Geoff Wong, Trish Greenhalgh, Gill Westhorp, Jeanette Buckingham, Ray Pawson BMC Medicine 2013, 11:21 (29 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Geoff Wong, Trish Greenhalgh et al. propose new publication guidelines for realist synthesis and meta-narrative reviews. The ‘RAMESES’ (Realist and Meta-review Evidence Synthesis: Evolving Standards) statement provides researchers, institutes and journals with guidance on how to conduct these new forms of literature analysis, and adherence to the guidelines will lead to quality assurance and uniform reporting of studies.
		Guideline RAMESES publication standards: meta-narrative reviews Geoff Wong, Trish Greenhalgh, Gill Westhorp, Jeanette Buckingham, Ray Pawson BMC Medicine 2013, 11:20 (29 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Geoff Wong, Trish Greenhalgh et al. propose new publication guidelines for realist synthesis and meta-narrative reviews. The ‘RAMESES’ (Realist and Meta-review Evidence Synthesis: Evolving Standards) statement provides researchers, institutes and journals with guidance on how to conduct these new forms of literature analysis, and adherence to the guidelines will lead to quality assurance and uniform reporting of studies.
		Commentary Sleeping well Mithu Sen, G Bryan Young BMC Medicine 2013, 11:19 (24 January 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Mithu Sen and Bryan Young comment on recent findings that actigraphy can reliably measure Vegetative and Minimally Conscious state sleep-wake cycles, and discuss the importance of improved prognostic methods for this challenging group of patients.
		Research article Actigraphy assessments of circadian sleep-wake cycles in the Vegetative and Minimally Conscious States Damian Cruse, Aurore Thibaut, Athena Demertzi, Julia C Nantes, Marie-Aurélie Bruno, Olivia Gosseries, Audrey Vanhaudenhuyse, Tristan A Bekinschtein, Adrian M Owen, Steven Laureys BMC Medicine 2013, 11:18 (24 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Wrist actigraphy indicates that the sleep-wake cycles of patients in Vegetative states are more impaired than those in Minimally Conscious states indicating a need for improved guidelines in assessing the circadian rhythms of these patients.
		Review Old drugs, old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs? Vasco Romão, Helena Canhão, João Fonseca BMC Medicine 2013, 11:17 (23 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary João Fonseca and colleagues review genetic and non-genetic predictors of response to therapy in patients with rheumatoid arthritis, and discuss how predictive markers could be used to select individual patients for the most appropriate treatment.
		Commentary Smoking and HIV: time for a change? Nicola Petrosillo, Stefania Cicalini BMC Medicine 2013, 11:16 (22 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Nicola Petrosillo and Stefania Cicalini comment on a meta-analysis showing that smoking increases the risk of pneumonia in people with HIV, and discuss the importance of incorporating smoking cessation into HIV care programs.
		Research article Systematic review and meta-analysis: influence of smoking cessation on incidence of pneumonia in HIV Preeti De, Amanda Farley, Nicola Lindson, Paul Aveyard BMC Medicine 2013, 11:15 (22 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Evidence from a systematic review and meta-analysis suggests that smoking increases the risk of bacterial pneumonia in people with HIV, and the risk is reduced in former smokers, highlighting the importance of smoking cessation for these patients.
		Opinion The young osteoarthritic knee: dilemmas in management Paul M Sutton, Edward S Holloway BMC Medicine 2013, 11:14 (18 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The prevalence of osteoarthritis (OA) in the knees is increasing in younger patients due to modern lifestyles; Paul Sutton and Edward Holloway discuss the considerations orthopedic surgeons should take into account when treating this specific age group.

	All
		Research article Sodium vanadate combined with L-ascorbic acid delays disease progression, enhances motor performance, and ameliorates muscle atrophy and weakness in mice with spinal muscular atrophy Huei-Chun Liu, Chen-Hung Ting, Hsin-Lan Wen, Li-Kai Tsai, Hsiu-Mei Hsieh-Li, Hung Li, Sue Lin-Chao BMC Medicine 2013, 11:38 (14 February 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Combined therapy of sodium vanadate with L-ascorbic acid delays disease progression and enhances motor performance in mice, as well as reducing toxicity, indicating an improved strategy for treating of late onset spinal muscular atrophy (SMA)
		Review Peri-operative interventions producing better functional outcomes and enhanced recovery following total hip and knee arthroplasty: an evidence-based review Mazin S Ibrahim, Muhammad A Khan, Ikram Nizam, Fares S Haddad BMC Medicine 2013, 11:37 (13 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Fares Haddad and colleagues review peri-operative interventions for improved patient outcomes after total knee and hip replacements, which aim to improve patient quality of life and lessen the economic burden by reducing length of hospital stay.
		Commentary A practical method to target individuals for outbreak detection and control Gerardo Chowell, Cécile Viboud BMC Medicine 2013, 11:36 (12 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Gerardo Chowell and Cécile Viboud comment on a novel method that identifies risk of influenza transmission and allows early detection of infection in schools, but caution that this promising method needs testing on outbreaks in different settings.
		Research article A low-cost method to assess the epidemiological importance of individuals in controlling infectious disease outbreaks Timo Smieszek, Marcel Salathé BMC Medicine 2013, 11:35 (12 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A low-cost ranking method for modeling the spread of influenza in schools identifies subpopulations at higher risk of early infection than randomly selected communities, which could be effective for predicting and preventing epidemics.
		Commentary Managing the risk of lithium-induced nephropathy in the long-term treatment of patients with recurrent affective disorders Emanuel Severus, Michael Bauer BMC Medicine 2013, 11:34 (11 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Emanuel Severus and Michael Bauer comment on recent research that showed kidney toxicity is associated with duration of lithium treatment and age, and discuss the importance of managing renal function in patients on long-term lithium therapy.
		Research article Duration of lithium treatment is a risk factor for reduced glomerular function: a cross-sectional study Alberto Bocchetta, Raffaella Ardau, Paolo Carta, Franca Ligas, Claudia Sardu, Antonello Pani, Maria Del Zompo BMC Medicine 2013, 11:33 (11 February 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In patients with affective disorders, the duration of lithium treatment and advanced age are risk factors for glomerular failure, suggesting that kidney toxicity should be weighed against the protective effects of lithium in these patients.
		Research article The effects of apoptosis vulnerability markers on the myocardium in depression after myocardial infarction Yiming Wang, Xingde Liu, Dongfeng Zhang, Jianhui Chen, Shuzheng Liu, Michael Berk BMC Medicine 2013, 11:32 (8 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Pro-apoptotic pathways in the heart are upregulated in rats that have suffered post-myocardial infarction (MI) depression, and these pathophysiological processes may underlie the increased incidence of depression in patients following MI.
		Review The sweet and sour of serological glycoprotein tumor biomarker quantification Uros Kuzmanov, Hari Kosanam, Eleftherios P Diamandis BMC Medicine 2013, 11:31 (7 February 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary As there has been limited success in the development of glycoprotein tumor markers, Eleftherios Diamandis and colleagues review the challenges, and discuss how new technology will facilitate quantification of these biomarkers for clinical use.
		Commentary Fat dads must not be blamed for their children's health problems Gudrun E Moore, Philip Stanier BMC Medicine 2013, 11:30 (6 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Gudrun Moore and Philip Stainer comment on a recent study showing that fathers’ obesity is related to gene methylation changes in offspring, but highlight that the results should not be over-emphasized and future studies should consider whole genomes.
		Research article Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort Adelheid Soubry, Joellen M Schildkraut, Amy Murtha, Frances Wang, Zhiqing Huang, Autumn Bernal, Joanne Kurtzberg, Randy L Jirtle, Susan K Murphy, Cathrine Hoyo BMC Medicine 2013, 11:29 (6 February 2013) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology \| Editor’s summary Obesity in fathers is associated with a decrease in methylation of the insulin-like growth factor 2 gene in their newborns, suggesting that paternal obesity may disrupt normal imprinting in germ cells and affect the health of their offspring.
		Review Depression pathogenesis and treatment: what can we learn from blood mRNA expression? Nilay Hepgul, Annamaria Cattaneo, Patricia A Zunszain, Carmine M Pariante BMC Medicine 2013, 11:28 (5 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Carmine Pariante and colleagues review the altered pattern of peripheral gene expression in patients with major depressive disorder, and comment on the clinical applicability of potential biomarkers to measure these reversible changes in patients.
		Commentary Multigenerational epigenetic effects of nicotine on lung function Frances M Leslie BMC Medicine 2013, 11:27 (4 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A recent study in rats showed nicotine exposure during pregnancy results in significant multigenerational effects; in light of these findings Frances Leslie discusses the importance of effective smoking cessation strategies during pregnancy.
		Minireview Epigenetic mechanisms in migraine: a promising avenue? Else Eising, Nicole A Datson, Arn MJM van den Maagdenberg, Michel D Ferrari BMC Medicine 2013, 11:26 (4 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Michel Ferrari and colleagues review the evidence for potential epigenetic mechanisms behind migraine pathology, which may provide therapeutic targets for novel prophylactic strategies.
		Research article Genetic discrimination and life insurance: a systematic review of the evidence Yann Joly, Ida Ngueng Feze, Jacques Simard BMC Medicine 2013, 11:25 (31 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Evidence from a systematic review of genetic discrimination studies shows that individual cases of discrimination exist in the context of life insurance, but policy action cannot be justified at present due to limitations of the studies.
		Research article The global burden of neonatal hypothermia: systematic review of a major challenge for newborn survival Karsten Lunze, David E Bloom, Dean T Jamison, Davidson H Hamer BMC Medicine 2013, 11:24 (31 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Evidence from a systematic review shows that neonatal hypothermia indirectly contributes to infant mortality, suggesting that hypothermia prevention measures should be employed to help reduce newborn deaths in resource-limited settings.
		Correspondence Economic analyses to support decisions about HPV vaccination in low- and middle-income countries: a consensus report and guide for analysts Mark Jit, Carol Levin, Marc Brisson, Ann Levin, Stephen Resch, Johannes Berkhof, Jane Kim, Raymond Hutubessy BMC Medicine 2013, 11:23 (30 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary An expert group from the World Health Organization provides advice on economic issues associated with human papillomavirus (HPV) vaccination in low- and middle-income countries (LMICs), recommending that analyses are thorough, but not overly complex.
		Commentary Meta-narrative and realist reviews: guidance, rules, publication standards and quality appraisal David Gough BMC Medicine 2013, 11:22 (29 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary David Gough comments on the release of the RAMESES publication reporting standards, and emphasizes the importance of applying rigorous research methods, whilst also maintaining quality appraisal and transparency.
		Guideline RAMESES publication standards: realist syntheses Geoff Wong, Trish Greenhalgh, Gill Westhorp, Jeanette Buckingham, Ray Pawson BMC Medicine 2013, 11:21 (29 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Geoff Wong, Trish Greenhalgh et al. propose new publication guidelines for realist synthesis and meta-narrative reviews. The ‘RAMESES’ (Realist and Meta-review Evidence Synthesis: Evolving Standards) statement provides researchers, institutes and journals with guidance on how to conduct these new forms of literature analysis, and adherence to the guidelines will lead to quality assurance and uniform reporting of studies.
		Guideline RAMESES publication standards: meta-narrative reviews Geoff Wong, Trish Greenhalgh, Gill Westhorp, Jeanette Buckingham, Ray Pawson BMC Medicine 2013, 11:20 (29 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Geoff Wong, Trish Greenhalgh et al. propose new publication guidelines for realist synthesis and meta-narrative reviews. The ‘RAMESES’ (Realist and Meta-review Evidence Synthesis: Evolving Standards) statement provides researchers, institutes and journals with guidance on how to conduct these new forms of literature analysis, and adherence to the guidelines will lead to quality assurance and uniform reporting of studies.
		Commentary Sleeping well Mithu Sen, G Bryan Young BMC Medicine 2013, 11:19 (24 January 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Mithu Sen and Bryan Young comment on recent findings that actigraphy can reliably measure Vegetative and Minimally Conscious state sleep-wake cycles, and discuss the importance of improved prognostic methods for this challenging group of patients.
		Research article Actigraphy assessments of circadian sleep-wake cycles in the Vegetative and Minimally Conscious States Damian Cruse, Aurore Thibaut, Athena Demertzi, Julia C Nantes, Marie-Aurélie Bruno, Olivia Gosseries, Audrey Vanhaudenhuyse, Tristan A Bekinschtein, Adrian M Owen, Steven Laureys BMC Medicine 2013, 11:18 (24 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Wrist actigraphy indicates that the sleep-wake cycles of patients in Vegetative states are more impaired than those in Minimally Conscious states indicating a need for improved guidelines in assessing the circadian rhythms of these patients.
		Review Old drugs, old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs? Vasco Romão, Helena Canhão, João Fonseca BMC Medicine 2013, 11:17 (23 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary João Fonseca and colleagues review genetic and non-genetic predictors of response to therapy in patients with rheumatoid arthritis, and discuss how predictive markers could be used to select individual patients for the most appropriate treatment.
		Commentary Smoking and HIV: time for a change? Nicola Petrosillo, Stefania Cicalini BMC Medicine 2013, 11:16 (22 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Nicola Petrosillo and Stefania Cicalini comment on a meta-analysis showing that smoking increases the risk of pneumonia in people with HIV, and discuss the importance of incorporating smoking cessation into HIV care programs.
		Research article Systematic review and meta-analysis: influence of smoking cessation on incidence of pneumonia in HIV Preeti De, Amanda Farley, Nicola Lindson, Paul Aveyard BMC Medicine 2013, 11:15 (22 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Evidence from a systematic review and meta-analysis suggests that smoking increases the risk of bacterial pneumonia in people with HIV, and the risk is reduced in former smokers, highlighting the importance of smoking cessation for these patients.
		Opinion The young osteoarthritic knee: dilemmas in management Paul M Sutton, Edward S Holloway BMC Medicine 2013, 11:14 (18 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The prevalence of osteoarthritis (OA) in the knees is increasing in younger patients due to modern lifestyles; Paul Sutton and Edward Holloway discuss the considerations orthopedic surgeons should take into account when treating this specific age group.