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1.

1479
Accesses

Research article   Open Access Highly Accessed

Comparison of static immersion and intravenous injection systems for exposure of zebrafish embryos to the natural pathogen Edwardsiella tarda

Joost J van Soest, Oliver W Stockhammer, Anita Ordas, Guido V Bloemberg, Herman P Spaink, Annemarie H Meijer BMC Immunology 2011, 12:58 (17 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

2.

1275
Accesses

Methodology article   Open Access Highly Accessed

Expression profiling of lymph node cells from deer mice infected with Andes virus

Tony Schountz, Timothy I Shaw, Travis C Glenn, Heinz Feldmann, Joseph Prescott BMC Immunology 2013, 14:18 (9 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Novel methodology for designing real-time PCR arrays in deer mice indicates that lymph node T cells from those infected with ANDV express mostly genes of the Th2 phenotype but fewer genes of Th1 and Treg phenotypes.

3.

870
Accesses

Research article   Open Access Highly Accessed

Characterization of murine macrophages from bone marrow, spleen and peritoneum

Changqi Wang, Xiao Yu, Qi Cao, Ya Wang, Guoping Zheng, Thian Kui Tan, Hong Zhao, Ye Zhao, Yiping Wang, David CH Harris BMC Immunology 2013, 14:6 (5 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A comparison study of mouse macrophages derived from spleen, bone marrow and peritoneum demonstrates their distinct characteristics which may be relevant to their respective roles in the immune response.

4.

842
Accesses

Research article   Open Access Highly Accessed

Revisiting the white blood cell count: immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis - a prospective, observational study

Axel Nierhaus, Stefanie Klatte, Jo Linssen, Nina M Eismann, Dominic Wichmann, Jörg Hedke, Stephan A Braune, Stefan Kluge BMC Immunology 2013, 14:8 (12 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Immature granulocyte (IG) count in peripheral blood is an effective marker for identifying infected patients during the early onset of systemic inflammatory response syndrome (SIRS), suggesting routine measurement could offer new potential for rapid screening.

5.

709
Accesses

Research article   Open Access Highly Accessed

Interleukin-10 production by tumor infiltrating macrophages plays a role in Human Papillomavirus 16 tumor growth

Aline Bolpetti, João S Silva, Luisa L Villa, Ana Lepique BMC Immunology 2010, 11:27 (7 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

In the human papillomavirus 16 (HPV16) associated tumor mouse model, interleukin 10 (IL-10) from tumor macrophages induces the infiltration of regulatory T cells, and inhibits anti-tumor activity thereby facilitating tumor growth, while blocking IL-10 signaling reduces tumor growth.

6.

709
Accesses

Research article   Open Access Highly Accessed

Cytokine expression during early and late phase of acute Puumala hantavirus infection

Mahmoud Sadeghi, Isabella Eckerle, Volker Daniel, Ulrich Burkhardt, Gerhard Opelz, Paul Schnitzler BMC Immunology 2011, 12:65 (16 November 2011)

Abstract | Full text | PDF | PubMed

7.

673
Accesses

Research article   Open Access Highly Accessed

The inhibitory effect against collagen-induced arthritis by Schistosoma japonicum infection is infection stage-dependent

YunKun He, Jia Li, WenJia Zhuang, Lan Yin, ChunXia Chen, Jun Li, FengLi Chi, YanShuang Bai, Xiao-Ping Chen BMC Immunology 2010, 11:28 (10 June 2010)

Abstract | Full text | PDF | PubMed

8.

673
Accesses

Research article   Open Access Highly Accessed

The absence of MyD88 has no effect on the induction of alternatively activated macrophage during Fasciola hepatica infection

HongLin Luo, Weiyi Huang, Dongying Wang, Haoju Wang, Kui Nie BMC Immunology 2011, 12:63 (11 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

9.

642
Accesses

Research article   Open Access Highly Accessed

Immune responses of Helicoverpa armigera to different kinds of pathogens

Qian Wang, Yang Liu, Hong-Juan He, Xiao-Fan Zhao, Jin-Xing Wang BMC Immunology 2010, 11:9 (3 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

640
Accesses

Research article   Open Access Highly Accessed

A comparison of sex-specific immune signatures in Gulf War illness and chronic fatigue syndrome

Anne Smylie, Gordon Broderick, Henrique Fernandes, Shirin Razdan, Zachary Barnes, Fanny Collado, Connie Sol, Mary Fletcher, Nancy Klimas BMC Immunology 2013, 14:29 (25 June 2013)

Abstract | Full text | PDF | ePUB | PubMed

11.

607
Accesses

Research article   Open Access

Impact of acute stress on antimicrobial polypeptides mRNA copy number in several tissues of marine sea bass (Dicentrarchus labrax)

Genciana Terova, Anna G Cattaneo, Elena Preziosa, Giovanni Bernardini, Marco Saroglia BMC Immunology 2011, 12:69 (28 December 2011)

Abstract | Full text | PDF | PubMed

12.

515
Accesses

Research article   Open Access Highly Accessed

Bacillus anthracis’ lethal toxin induces broad transcriptional responses in human peripheral monocytes

Kassidy M Chauncey, M Lopez, Gurjit Sidhu, Sarah E Szarowicz, Henry V Baker, Conrad Quinn, Frederick S Southwick BMC Immunology 2012, 13:33 (2 July 2012)

Abstract | Full text | PDF | PubMed

13.

472
Accesses

Review   Open Access Highly Accessed

Revisiting the B-cell compartment in mouse and humans: more than one B-cell subset exists in the marginal zone and beyond

Olivier Garraud, Gwenoline Borhis, Gamal Badr, Séverine Degrelle, Bruno Pozzetto, Fabrice Cognasse, Yolande Richard BMC Immunology 2012, 13:63 (29 November 2012)

Abstract | Full text | PDF | PubMed

14.

466
Accesses

Research article   Open Access Highly Accessed

MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS)

Margareta Jernås, Clas Malmeström, Markus Axelsson, Intawat Nookaew, Hans Wadenvik, Jan Lycke, Bob Olsson BMC Immunology 2013, 14:32 (29 July 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Genome-wide expression analyses in T-cells from multiple sclerosis (MS) patients identifies multiple differentially expressed microRNAs that affect the expression of target genes associated with the immune system, suggesting a important regulatory role for microRNA in MS.

15.

446
Accesses

Research article   Open Access Highly Accessed

Significantly reduced CCR5-tropic HIV-1 replication in vitro in cells from subjects previously immunized with Vaccinia Virus

Raymond S Weinstein, Michael M Weinstein, Kenneth Alibek, Michael I Bukrinsky, Beda Brichacek BMC Immunology 2010, 11:23 (18 May 2010)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

HIV replicates slower in cells from individuals previously vaccinated against smallpox than in cells from unvaccinated subjects, suggesting a potential link between the end of smallpox vaccination programs and the exponential spread of HIV.

16.

423
Accesses

Research article   Open Access Highly Accessed

DNA vaccines targeting the encoded antigens to dendritic cells induce potent antitumor immunity in mice

Jun Cao, Yiqi Jin, Wei Li, Bin Zhang, Yang He, Hongqiang Liu, Ning Xia, Huafeng Wei, Jian Yan BMC Immunology 2013, 14:39 (14 August 2013)

Abstract | Full text | PDF | ePUB | PubMed

17.

421
Accesses

Research article   Open Access Highly Accessed

CTLA4-Ig (abatacept) therapy modulates T cell effector functions in autoantibody-positive rheumatoid arthritis patients

Jennifer Pieper, Jessica Herrath, Sukanya Raghavan, Khalid Muhammad, Ronald van Vollenhoven, Vivianne Malmström BMC Immunology 2013, 14:34 (5 August 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Immunological study of T cell functionality in rheumatoid arthritis patients, both ACPA-positive and ACPA-negative, starting biological therapy with the co-stimulation blockade abatacept (CTLA4-Ig), supports the recently published registry study implicating ACPA seropositivity as an independent predictive factor to treatment response.

18.

394
Accesses

Research article   Open Access Highly Accessed

Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays

Wilco de Jager, Katarzyna Bourcier, Ger T Rijkers, Berent J Prakken, Vicki Seyfert-Margolis BMC Immunology 2009, 10:52 (28 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

19.

389
Accesses

Research article   Open Access

Alveolar macrophages of GM-CSF knockout mice exhibit mixed M1 and M2 phenotypes

Heidi Dalrymple, Barbara P Barna, Anagha Malur, Achut G Malur, Mani S Kavuru, Mary Thomassen BMC Immunology 2013, 14:41 (17 September 2013)

Abstract | Full text | PDF | PubMed

20.

375
Accesses

Research article   Open Access

The timing of TGF-β inhibition affects the generation of antigen-specific CD8+ T Cells

Jon G Quatromoni, Eiji Suzuki, Olugbenga Okusanya, Brendan F Judy, Pratik Bhojnagarwala, Ollin Venegas, Evgeniy Eruslanov, Jarrod D Predina, Steven M Albelda, Sunil Singhal BMC Immunology 2013, 14:30 (17 July 2013)

Abstract | Full text | PDF | PubMed

21.

373
Accesses

Research article   Open Access Highly Accessed

Toll-like receptor 4 (TLR4) expression in human and murine pancreatic beta-cells affects cell viability and insulin homeostasis

Humberto M Garay-Malpartida, Roberta F Mourão, Marluce Mantovani, Icaro A Santos, Mari C Sogayar, Anna C Goldberg BMC Immunology 2011, 12:18 (28 February 2011)

Abstract | Full text | PDF | PubMed

22.

361
Accesses

Proceedings   Open Access

Second international congress on immunopharmacology: delivery systems and current strategies for drug design

Reinaldo Acevedo, Mario Landys, Armando Acosta, Herve Bercovier, Mohd Nor Norazmi, Valerie Ferro, Maria Elena Sarmiento BMC Immunology 2013, 14(Suppl 1):S1 (25 February 2013)

Full text | PDF | PubMed

23.

355
Accesses

Research article   Open Access Highly Accessed

Transcriptional profiling of the LPS induced NF-κB response in macrophages

Omar Sharif, Viacheslav N Bolshakov, Stephanie Raines, Peter Newham, Neil D Perkins BMC Immunology 2007, 8:1 (12 January 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

346
Accesses

Research article   Open Access

Nasally administered Lactobacillus rhamnosus strains differentially modulate respiratory antiviral immune responses and induce protection against respiratory syncytial virus infection

Yohsuke Tomosada, Eriko Chiba, Hortensia Zelaya, Takuya Takahashi, Kohichiro Tsukida, Haruki Kitazawa, Susana Alvarez, Julio Villena BMC Immunology 2013, 14:40 (15 August 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Comparative studies using two Lactobacillus rhamnosus strains demonstrate that nasal administration of immunobiotics beneficially modulate immune responses in the respiratory tract and increase resistance to Respiratory Syncytial Virus challenge in mice.

25.

321
Accesses

Research article   Open Access Highly Accessed

CD11b+Ly6C++Ly6G- cells show distinct function in mice with chronic inflammation or tumor burden

Eva Källberg, Martin Stenström, David Liberg, Fredrik Ivars, Tomas Leanderson BMC Immunology 2012, 13:69 (12 December 2012)

Abstract | Full text | PDF | PubMed

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