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Toll-like receptor 4 (TLR4) expression in human and murine pancreatic beta-cells affects cell viability and insulin homeostasis
Humberto M Garay-Malpartida, Roberta F Mourão, Marluce Mantovani, Icaro A Santos, Mari C Sogayar, Anna C Goldberg BMC Immunology 2011, 12:18 (28 February 2011)
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T cells fail to develop in the human skin-cell explants system; an inconvenient truth
Bob Meek, Catharina HMJ Van Elssen, Mirelle JAJ Huijskens, Sjoukje JC van der Stegen, Siebe Tonnaer, Stijn BJ Lumeij, Joris Vanderlocht, Mark A Kirkland, Reinout Hesselink, Wilfred TV Germeraad, Gerard MJ Bos BMC Immunology 2011, 12:17 (18 February 2011)
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Down-regulation of granulocyte-macrophage colony-stimulating factor by 3C-like proteinase in transfected A549 human lung carcinoma cells
Hsien-Hua Liao, Yao-Chen Wang, Miles Chen, Hsien-Yu Tsai, Johnson Lin, Shui-Tein Chen, Gregory Tsay, Sun-Long Cheng BMC Immunology 2011, 12:16 (17 February 2011)
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Differential utilization of NF-kappaB RELA and RELB in response to extracellular versus intracellular polyIC stimulation in HT1080 cells
James J Yun, Ming-Sound Tsao, Sandy D Der BMC Immunology 2011, 12:15 (10 February 2011)
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Increased susceptibility of 129SvEvBrd mice to IgE-Mast cell mediated anaphylaxis
Muthuvel Arumugam, Richard Ahrens, Heather Osterfeld, Leah C Kottyan, Xun Shang, John A Maclennan, Nives Zimmermann, Yi Zheng, Fred D Finkelman, Simon P Hogan BMC Immunology 2011, 12:14 (3 February 2011)
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Editor’s summary
Substantial strain-dependent differences between the mast cells of 129SvEvBrd and BALB/c mice increase the susceptibility of the 129SvEvBrd mouse strain to anaphylaxis and caution should be taken when interpreting results from embryonic stem cells from this strain.
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Babassu aqueous extract (BAE) as an adjuvant for T helper (Th)1-dependent immune responses in mice of a Th2 immune response-prone strain
Rosane NM Guerra, Virgínia MG Silva, Luciana S Aragão-França, Pablo R Oliveira, Rodrigo Feitosa, Flavia RF Nascimento, Lain C Pontes-de-Carvalho BMC Immunology 2011, 12:13 (29 January 2011)
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Editor’s summary
Babassu aqueous extract (BAE) preferentially promotes a Th1-dependent immune response in mice of a Th2 immune response-prone strain, which may prove useful in the control of diseases mediated by Th2 immune responses, such as allergic asthma and rhinitis.
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TNFA deletion alters apoptosis as well as caspase 3 and 4 expression during otitis media
Joerg Ebmeyer, Anke Leichtle, Michelle Hernandez, Umay Ebmeyer, Jacob Husseman, Kwang Pak, Holger Sudhoff, David Broide, Stephen I Wasserman, Allen F Ryan BMC Immunology 2011, 12:12 (26 January 2011)
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Ketamine inhibits tumor necrosis factor secretion by RAW264.7 murine macrophages stimulated with antibiotic-exposed strains of community-associated, methicillin-resistant Staphylococcus aureus
Thomas Spentzas, Rebekah KH Shapley, Carlos Aguirre, Elizabeth Meals, Lauren Lazar, Mark S Rayburn, Brett S Walker, B Keith English BMC Immunology 2011, 12:11 (25 January 2011)
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Human neutrophil migration and activation by BJcuL, a galactose binding lectin purified from Bothrops jararacussu venom
Selene Elifio-Esposito, Luciane Tomazeli, Carolina Schwartz, Ana Gimenez, Gabriel M Fugii, Luiz Fernandes, Luciana FM Zishler, Patrícia M Stuelp-Campelo, Andréa N Moreno BMC Immunology 2011, 12:10 (25 January 2011)
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Editor’s summary
BJcuL, a galactose binding lectin purified from snake venom, can recognize glycoligands on the neutrophil surface and can promote in vitro polarization, migration and adhesion to extracellular matrix proteins.
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Caries induced cytokine network in the odontoblast layer of human teeth
Orapin V Horst, Jeremy A Horst, Ram Samudrala, Beverly A Dale BMC Immunology 2011, 12:9 (24 January 2011)
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Editor’s summary
The odontoplast layer of the tooth amplifies bacterial signals by self-feedback cytokine-chemokine signal-receptor cycling, increasing the defensive capacity of the tooth and thereby restricting the battle against carious bacteria within the dentin.
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Evaluation of signal transduction pathways after transient cutaneous adenoviral gene delivery
Lars Steinstraesser, Michael Sorkin, Frank Jacobsen, Sammy Al-Benna, Marco Kesting, Andreas Niederbichler, Jan-Michel Otte, Tobias Hirsch, Jadwiga Stupka, Hans-Ulrich Steinau, Matthias Schulte BMC Immunology 2011, 12:8 (21 January 2011)
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Autoreactive marginal zone B cells enter the follicles and interact with CD4+ T cells in lupus-prone mice
Zhenhai Zhou, Haitao Niu, Ying-Yi Zheng, Laurence Morel BMC Immunology 2011, 12:7 (20 January 2011)
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Persistence of virus-specific immune responses in the central nervous system of mice after West Nile virus infection
Barbara S Stewart, Valerie L Demarest, Susan J Wong, Sharone Green, Kristen A Bernard BMC Immunology 2011, 12:6 (20 January 2011)
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Prevalent de novo somatic mutations in superantigen genes of mouse mammary tumor viruses in the genome of C57BL/6J mice and its potential implication in the immune system
Young-Kwan Lee, Sophia Chiu, Alex Chew, David G Greenhalgh, Kiho Cho BMC Immunology 2011, 12:5 (18 January 2011)
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Immunoregulatory effects of AFP domains on monocyte-derived dendritic cell function
Agus Setiyono, Akterono D Budiyati, Sigit Purwantomo, Madonna R Anggelia, Ismail Fanany, Gunawan A Wibowo, Indra Bachtiar, Andi Utama, Susan Tai BMC Immunology 2011, 12:4 (17 January 2011)
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Shb deficient mice display an augmented TH2 response in peripheral CD4+ T cells
Karin Gustafsson, Gabriela Calounova, Fredrik Hjelm, Vitezslav Kriz, Birgitta Heyman, Kjell-Olov Grönvik, Gustavo Mostoslavsky, Michael Welsh BMC Immunology 2011, 12:3 (11 January 2011)
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Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses
Arnt-Ove Hovden, Marie Karlsen, Roland Jonsson, Hans Aarstad, Silke Appel BMC Immunology 2011, 12:2 (5 January 2011)
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Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide
Mingyong Wang, Yani Zhang, Yue Chen, Liyun Zhang, Xiao Lu, Zhengliang Chen BMC Immunology 2011, 12:1 (1 January 2011)
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Intranasal immunization with plasmid DNA encoding spike protein of SARS-coronavirus/polyethylenimine nanoparticles elicits antigen-specific humoral and cellular immune responses
Byoung-Shik Shim, Sung-Moo Park, Ji-Shan Quan, Dhananjay Jere, Hyuk Chu, Man Song, Dong Kim, Yong-Suk Jang, Moon-Sik Yang, Seung Han, Yong-Ho Park, Chong-Su Cho, Cheol-Heui Yun BMC Immunology 2010, 11:65 (31 December 2010)
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Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection
Wei-Chuan Chang, Mitchell R White, Patience Moyo, Sheree McClear, Steffen Thiel, Kevan L Hartshorn, Kazue Takahashi BMC Immunology 2010, 11:64 (23 December 2010)
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Bifidobacterium animalis AHC7 protects against pathogen-induced NF-κB activation in vivo
David O'Mahony, Sharon Murphy, Thomas Boileau, JeanSoon Park, Frances O'Brien, David Groeger, Patrycja Konieczna, Mario Ziegler, Paul Scully, Fergus Shanahan, Barry Kiely, Liam O'Mahony BMC Immunology 2010, 11:63 (22 December 2010)
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Iloprost modulates the immune response in systemic sclerosis
Patrizia D'Amelio, Maria A Cristofaro, Lucia D'Amico, Luciana Veneziano, Ilaria Roato, Francesca Sassi, Giuseppina Bisignano, Marta Saracco, Raffaele Pellerito, Salvatore Patanè, Riccardo Ferracini, Gian P Pescarmona, Giovanni C Isaia BMC Immunology 2010, 11:62 (15 December 2010)
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Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease
Sara Bogaert, Debby Laukens, Harald Peeters, Lode Melis, Kim Olievier, Nico Boon, Gust Verbruggen, Jo Vandesompele, Dirk Elewaut, Martine De Vos BMC Immunology 2010, 11:61 (13 December 2010)
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In vivo trafficking and immunostimulatory potential of an intranasally-administered primary dendritic cell-based vaccine
Prachi Vilekar, Vibhudutta Awasthi, Pallavi Lagisetty, Catherine King, Nathan Shankar, Shanjana Awasthi BMC Immunology 2010, 11:60 (10 December 2010)
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Editor’s summary
An intranasally-administered primary dendritic cell (DC)-based vaccine for the fungal disease Coccidioidomycosis, prepared by nonviral genetic-transfection, migrates to both lymphoid and non-lymphoid organs and is capable of inducing an antigen-specific T cell response.
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Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array
András Szarka, János Rigó, Levente Lázár, Gabriella Bekő, Attila Molvarec BMC Immunology 2010, 11:59 (2 December 2010)
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CD8+ T cell activation predominate early immune responses to hypercholesterolemia in Apoe-/- mice
Daniel Kolbus, Ornélia H Ramos, Katarina E Berg, Josefin Persson, Maria Wigren, Harry Björkbacka, Gunilla Fredrikson, Jan Nilsson BMC Immunology 2010, 11:58 (2 December 2010)
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TGF-β-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPK
Maren Bakkebø, Kanutte Huse, Vera I Hilden, Erlend B Smeland, Morten P Oksvold BMC Immunology 2010, 11:57 (23 November 2010)
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Rapid induction of IgE responses to a worm cysteine protease during murine pre-patent schistosome infection
Lucia A de Oliveira Fraga, Erika W Lamb, Elizabeth C Moreno, Mitali Chatterjee, Jan Dvořák, Melaine Delcroix, Mohammed Sajid, Conor R Caffrey, Stephen J Davies BMC Immunology 2010, 11:56 (15 November 2010)
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Novel Method of Monitoring Trace Cytokines and Activated STAT Molecules in the Paws of Arthritic Mice using Multiplex Bead Technology
Lily D Lu, Kristine L Stump, Matthew M Seavey BMC Immunology 2010, 11:55 (12 November 2010)
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Editor’s summary
A novel method for extracting joint fluid from the paws of mice with rheumatoid arthritis (RA) enables multiple potential biomarkers to be monitored simultaneously directly ex vivo and is applicable to multiple autoimmunity model types.
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Phenotype, functions and fate of adoptively transferred tumor draining lymphocytes activated ex vivo in mice with an aggressive weakly immunogenic mammary carcinoma
Catriona HT Miller, Laura Graham, Harry D Bear BMC Immunology 2010, 11:54 (4 November 2010)
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PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes
Maryam G Rohani, Dennis H DiJulio, Jonathan Y An, Beth M Hacker, Beverly A Dale, Whasun O Chung BMC Immunology 2010, 11:53 (28 October 2010)
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Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages
Amrita D Joshi, Sameer R Oak, Adam J Hartigan, William G Finn, Steven L Kunkel, Karen E Duffy, Anuk Das, Cory M Hogaboam BMC Immunology 2010, 11:52 (19 October 2010)
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The gastrointestinal nematode Trichostrongylus colubriformis down-regulates immune gene expression in migratory cells in afferent lymph
Jacqueline S Knight, David B Baird, Wayne R Hein, Anton Pernthaner BMC Immunology 2010, 11:51 (17 October 2010)
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Macrophage migration inhibitory factor regulates interleukin-6 production by facilitating nuclear factor-kappa B activation during Vibrio vulnificus infection
Chia-Chang Chuang, Yin-Ching Chuang, Wen-Teng Chang, Chi-Chung Chen, Lien-I Hor, A-Ming Huang, Pui-Ching Choi, Chi-Yun Wang, Po-Chin Tseng, Chiou-Feng Lin BMC Immunology 2010, 11:50 (12 October 2010)
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Natural killer cells are crucial for the efficacy of Icon (factor VII/human IgG1 Fc) immunotherapy in human tongue cancer
Zhiwei Hu, Jing Li BMC Immunology 2010, 11:49 (12 October 2010)
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Associations between SNPs in candidate immune-relevant genes and rubella antibody levels: a multigenic assessment
V Shane Pankratz, Robert A Vierkant, Megan M O'Byrne, Inna G Ovsyannikova, Gregory A Poland BMC Immunology 2010, 11:48 (5 October 2010)
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Bystander T cells in human immune responses to dengue antigens
Duangchan Suwannasaen, Arunrat Romphruk, Chanvit Leelayuwat, Ganjana Lertmemongkolchai BMC Immunology 2010, 11:47 (20 September 2010)
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Serum lipoproteins attenuate macrophage activation and Toll-Like Receptor stimulation by bacterial lipoproteins
Sylvette Bas, Richard W James, Cem Gabay BMC Immunology 2010, 11:46 (16 September 2010)
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Tumor vaccine composed of C-class CpG oligodeoxynucleotides and irradiated tumor cells induces long-term antitumor immunity
Petra Cerkovnik, Barbara Novakovic, Vida Stegel, Srdjan Novakovic BMC Immunology 2010, 11:45 (13 September 2010)
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Effects of F/G-actin ratio and actin turn-over rate on NADPH oxidase activity in microglia
Izabela Rasmussen, Line H Pedersen, Luise Byg, Kazuhiro Suzuki, Hideki Sumimoto, Frederik Vilhardt BMC Immunology 2010, 11:44 (8 September 2010)
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Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases
Paolo GV Martini, Lynette C Cook, Scott Alderucci, Angela W Norton, Dianna M Lundberg, Susan M Fish, Knut Langsetmo, Göran Jönsson, Christian Lood, Birgitta Gullstrand, Kate J Zaleski, Nancy Savioli, Jason Lottherand, Charles Bedard, John Gill, Michael F Concino, Michael W Heartlein, Lennart Truedsson, Jan L Powell, Arthur O Tzianabos BMC Immunology 2010, 11:43 (20 August 2010)
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Ultrastructural localization of extracellular matrix proteins of the lymph node cortex: evidence supporting the reticular network as a pathway for lymphocyte migration
Gregg P Sobocinski, Katherine Toy, Walter F Bobrowski, Stephen Shaw, Arthur O Anderson, Eric P Kaldjian BMC Immunology 2010, 11:42 (17 August 2010)
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Dynamics of dendritic cell maturation are identified through a novel filtering strategy applied to biological time-course microarray replicates
Amy L Olex, Elizabeth M Hiltbold, Xiaoyan Leng, Jacquelyn S Fetrow BMC Immunology 2010, 11:41 (3 August 2010)
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Peripheral blood T Regulatory cell counts may not predict transplant rejection
Yuchuan Huang, Juan Shan, Chuntao Zhang, Jie Zhang, Li Feng, Shengfu Li, Youping Li BMC Immunology 2010, 11:40 (15 July 2010)
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Changes in colon gene expression associated with increased colon inflammation in interleukin-10 gene-deficient mice inoculated with Enterococcus species
Matthew PG Barnett, Warren C McNabb, Adrian L Cookson, Shuotun Zhu, Marcus Davy, Bianca Knoch, Katia Nones, Alison J Hodgkinson, Nicole C Roy BMC Immunology 2010, 11:39 (15 July 2010)
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Editor’s summary
Gene expression patterns in the colon of IL-10 deficient mice, fed with Enterococcus or complex intestinal flora, are similar to those observed in human Inflammatory Bowel Disease (IBD), providing molecular confirmation of this IBD mouse model.
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Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREG cells
Elisabeth Ersvaer, Knut Liseth, Jørn Skavland, Bjørn Gjertsen, Øystein Bruserud BMC Immunology 2010, 11:38 (9 July 2010)
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Differential and coordinated expression of defensins and cytokines by gingival epithelial cells and dendritic cells in response to oral bacteria
Lei Yin, Takahiro Chino, Orapin V Horst, Beth M Hacker, Edward A Clark, Beverly A Dale, Whasun O Chung BMC Immunology 2010, 11:37 (9 July 2010)
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Adenovirus F protein as a delivery vehicle for botulinum B
Beata Clapp, Sarah Golden, Massimo Maddaloni, Herman F Staats, David W Pascual BMC Immunology 2010, 11:36 (7 July 2010)
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Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining
Steven G Smith, Maeve K Lalor, Patricia Gorak-Stolinska, Rose Blitz, Natalie ER Beveridge, Andrew Worth, Helen McShane, Hazel M Dockrell BMC Immunology 2010, 11:35 (7 July 2010)
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The antigen presentation function of bone marrow-derived mast cells is spatiotemporally restricted to a subset expressing high levels of cell surface FcεRI and MHC II
Jian Gong, Ning-Sun Yang, Michael Croft, I-Chun Weng, Liangwu Sun, Fu-Tong Liu, Swey-Shen Chen BMC Immunology 2010, 11:34 (30 June 2010)
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